2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Ac-EEVC-OH

Ac-EEVC-OH is the linker, that can be used for synthesis of ADC molecule.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-EEVC-OH Chemical Structure

Ac-EEVC-OH Chemical Structure

CAS No. : 2921734-44-1

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Based on 1 publication(s) in Google Scholar

Ac-EEVC-OH Related Antibodies

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Description

Ac-EEVC-OH is the linker, that can be used for synthesis of ADC molecule[1].

Molecular Weight

686.79

Formula

C31H54N6O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ac-Glu(t-Bu)-Glu(t-Bu)-Val-citrulline
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (145.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4560 mL 7.2802 mL 14.5605 mL
5 mM 0.2912 mL 1.4560 mL 2.9121 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4560 mL 7.2802 mL 14.5605 mL 36.4012 mL
5 mM 0.2912 mL 1.4560 mL 2.9121 mL 7.2802 mL
10 mM 0.1456 mL 0.7280 mL 1.4560 mL 3.6401 mL
15 mM 0.0971 mL 0.4853 mL 0.9707 mL 2.4267 mL
20 mM 0.0728 mL 0.3640 mL 0.7280 mL 1.8201 mL
25 mM 0.0582 mL 0.2912 mL 0.5824 mL 1.4560 mL
30 mM 0.0485 mL 0.2427 mL 0.4853 mL 1.2134 mL
40 mM 0.0364 mL 0.1820 mL 0.3640 mL 0.9100 mL
50 mM 0.0291 mL 0.1456 mL 0.2912 mL 0.7280 mL
60 mM 0.0243 mL 0.1213 mL 0.2427 mL 0.6067 mL
80 mM 0.0182 mL 0.0910 mL 0.1820 mL 0.4550 mL
100 mM 0.0146 mL 0.0728 mL 0.1456 mL 0.3640 mL
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Ac-EEVC-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-EEVC-OH2921734-44-1ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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