2. Peptides
  3. Peptide and Derivatives
  4. Peptides for Drug Delivery
  5. Peptide Linkers

Peptide Linkers

Custom Peptide Synthesis

Peptide linkers are short peptides used to connect functional molecules, and are often used to design fused proteins and conjugates such as ADCs and PDCs.

Peptide Linkers (24):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1449
    Boc-Gly-Gly-Phe-Gly-OH 187794-49-6 99.62%
    Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
    Boc-Gly-Gly-Phe-Gly-OH
  • HY-P10069
    Ac-pSar12-OH 2313534-24-4 99.52%
    Ac-pSar12-OH, as a linker, can be used for preparation of Ligand-Drug-Conjugate (LDC).
    Ac-pSar12-OH
  • HY-P10736A
    AMG133 peptide payload TFA 99.70%
    AMG133 peptide payload TFA is the TFA salt form of AMG133 peptide payload (HY-P10736). AMG133 peptide payload TFA is a GLP-1 agonist that can be used for synthesis of Maridebart cafraglutide (AMG133) (HY-164535) as a peptide linker conjugate.
    AMG133 peptide payload TFA
  • HY-P4192
    Fomc-Gly-Gly-Phe-Gly-OH 1817857-75-2 99.66%
    Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit.
    Fomc-Gly-Gly-Phe-Gly-OH
  • HY-136432
    Mc-Gly-Gly-Phe-Gly-PAB-OH 2632342-05-1 98.81%
    Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
    Mc-Gly-Gly-Phe-Gly-PAB-OH
  • HY-P11016
    PLGLAG 726172-45-8 99.63%
    PLGLAG is a peptide chain that serves as a linker in activatable cell-penetrating peptides (ACPPs). ACPPs containing the linker PLGLAG are primarily responsive to MMP-2 and MMP-9 in vivo. PLGLAG can be used in cancer research.
    PLGLAG
  • HY-P4166
    Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar 2857963-60-9 99.53%
    Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar is a decapeptide. Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar can be used to preparation of antibody-drug conjugate.
    Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar
  • HY-W142467
    Tetraglycine 637-84-3 98.09%
    Tetraglycine is a oligopeptide composed of four glycine monomers.
    Tetraglycine
  • HY-P3438A
    PRRVRLK acetate 98.18%
    PRRVRLK acetate is a peptide linker. PRRVRLK acetate can be used to make fusion protein.
    PRRVRLK acetate
  • HY-170534
    Ac-EEVC-OH 2921734-44-1 99.11%
    Ac-EEVC-OH is the linker, that can be used for synthesis of ADC molecule.
    Ac-EEVC-OH
  • HY-P3497
    Fmoc-Cys-Asp10 2407782-70-9
    Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.
    Fmoc-Cys-Asp10
  • HY-P3497A
    Fmoc-Cys-Asp10 TFA
    Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.
    Fmoc-Cys-Asp10 TFA
  • HY-136432A
    Mc-Gly-Gly-Phe-Gly-PAB-OH TFA
    Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
    Mc-Gly-Gly-Phe-Gly-PAB-OH TFA
  • HY-P3438
    PRRVRLK 2088834-66-4
    PRRVRLK is a peptide linker. PRRVRLK can be used to make fusion protein.
    PRRVRLK
  • HY-148031
    MC-Ala-Ala-Asn-PAB-PNP 1638970-45-2
    MC-Ala-Ala-Asn-PAB-PNP is a peptide, can be used to synthesize specifically activated micromolecular target coupling body.
    MC-Ala-Ala-Asn-PAB-PNP
  • HY-W142467A
    Tetraglycine hydrochloride 38126-71-5 99.19%
    Tetraglycine hydrochloride is a oligopeptide composed of four glycine monomers.
    Tetraglycine hydrochloride
  • HY-P4565
    Phe-Arg-Arg-Gly 642080-61-3
    Phe-Arg-Arg-Gly is a polypeptide that can be used for agent coupling.
    Phe-Arg-Arg-Gly
  • HY-P1449A
    Boc-Gly-Gly-Phe-Gly-OH TFA 2450273-39-7 98.27%
    Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
    Boc-Gly-Gly-Phe-Gly-OH TFA
  • HY-P10070
    Ac-pSar16-OH
    Ac-pSar16-OH is a polysarcosine which can replace PEG for therapeutic protein conjugation.
    Ac-pSar16-OH
  • HY-P3669
    Gly-Gly-Phe-Gly 200427-88-9 98.90%
    Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates.
    Gly-Gly-Phe-Gly