2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. HET0016 (Standard)

HET0016 (Standard) is the analytical standard of HET0016. This product is intended for research and analytical applications. HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid (20-HETE) synthase inhibitor, with IC50 values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth.

For research use only. We do not sell to patients.

HET0016 (Standard) Chemical Structure

HET0016 (Standard) Chemical Structure

CAS No. : 339068-25-6

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HET0016 (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HET0016 (Standard)339068-25-6Cytochrome P450CYPs20-HETE20-hydroxyeicosatetraenoicacid,CYP450CYP4A1CYP4A2CYP4A3Inhibitorinhibitorinhibit

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