Puxitatug samrotecan drug-linker  (Synonyms: AZD8205 drug-linker)

Puxitatug samrotecan drug-linker (AZD8205 drug-linker) is a drug-linker conjugate for ADC, which comprises a topoisomerase I inhibitor and a linker. Puxitatug samrotecan drug-linker can be used to synthesis antibody-drug conjugate (ADC), Puxitatug samrotecan (HY-171689)^[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1269.42

C₆₀H₈₄N₈O₂₀S

3025787-81-6

O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(C(CC6=O)SC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=CC7=C1COC([C@]7(O)CC)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Conilh L, et al. Payload diversification: a key step in the development of antibody–drug conjugates[J]. Journal of Hematology & Oncology, 2023, 16(1): 3.  [Content Brief]