Benzophenonetetracarboxylic dianhydride (Synonyms: BTDA)

Cat. No.: HY-W009169 Purity: 99.51%: Data Sheet
SDS

COA
Handling Instructions
FAQs
Technical Support

Benzophenonetetracarboxylic dianhydride is widely used in the synthesis of high-performance polyimides and other polymer materials. Benzophenonetetracarboxylic dianhydride reacts with various diamine compounds to form oligoimide chains. These oligimide chains can modify graphene oxide (Go) and enhance its properties.

For research use only. We do not sell to patients.

Benzophenonetetracarboxylic dianhydride Chemical Structure

CAS No. : 2421-28-5

Size	Stock	Quantity

Free Sample (0.1 - 0.5 mg)	Apply Now
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Description

Molecular Weight

322.23

Formula

C₁₇H₆O₇

CAS No.

2421-28-5

Appearance

Solid

Color

White to light yellow

SMILES

O=C(C1=CC2=C(C(OC2=O)=O)C=C1)C3=CC4=C(C(OC4=O)=O)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (310.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1034 mL	15.5170 mL	31.0339 mL
5 mM	0.6207 mL	3.1034 mL	6.2068 mL
10 mM	0.3103 mL	1.5517 mL	3.1034 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (15.52 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (15.52 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 5 mg/mL (15.52 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.51%

Select Batch:

Data Sheet (275 KB) SDS (393 KB)

COA (253 KB) HNMR (115 KB) RP-HPLC (225 KB)

Handling Instructions (2659 KB)

References

[1]. Khan MI, et al. ligoimide-Mediated Graphene Oxide-Epoxy Nanocomposites with Enhanced Thermal Conductivity and Mechanical Properties. Micromachines (Basel). 2022 Aug 24;13(9):1379.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.1034 mL	15.5170 mL	31.0339 mL	77.5848 mL
	5 mM	0.6207 mL	3.1034 mL	6.2068 mL	15.5170 mL
	10 mM	0.3103 mL	1.5517 mL	3.1034 mL	7.7585 mL
	15 mM	0.2069 mL	1.0345 mL	2.0689 mL	5.1723 mL
	20 mM	0.1552 mL	0.7758 mL	1.5517 mL	3.8792 mL
	25 mM	0.1241 mL	0.6207 mL	1.2414 mL	3.1034 mL
	30 mM	0.1034 mL	0.5172 mL	1.0345 mL	2.5862 mL
	40 mM	0.0776 mL	0.3879 mL	0.7758 mL	1.9396 mL
	50 mM	0.0621 mL	0.3103 mL	0.6207 mL	1.5517 mL
	60 mM	0.0517 mL	0.2586 mL	0.5172 mL	1.2931 mL
	80 mM	0.0388 mL	0.1940 mL	0.3879 mL	0.9698 mL
	100 mM	0.0310 mL	0.1552 mL	0.3103 mL	0.7758 mL

Benzophenonetetracarboxylic dianhydride Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Benzophenonetetracarboxylic dianhydride2421-28-5BTDADrug IntermediateDrug IintermediateHigh-performance polymersPolyimide synthesisChemical intermediateAdvanced adhesivesInhibitorinhibitorinhibit

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Benzophenonetetracarboxylic dianhydride (Synonyms: BTDA)

Benzophenonetetracarboxylic dianhydride Related Antibodies

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