2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. VP-U-6

VP-U-6 is a nucleoside analog that can be used in oligonucleotide synthesis.

For research use only. We do not sell to patients.

VP-U-6 Chemical Structure

VP-U-6 Chemical Structure

CAS No. : 2361324-80-1

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Based on 1 publication(s) in Google Scholar

VP-U-6 Related Antibodies

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Description

VP-U-6 is a nucleoside analog that can be used in oligonucleotide synthesis[1].

Molecular Weight

590.54

Formula

C24H40N4O9P2
CAS No.
Appearance

Oil

Color

Light yellow to yellow

SMILES

O=C(C=C1)NC(N1[C@@H]2O[C@H](/C=C/P(OCC)(OCC)=O)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H]2OC)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : ≥ 100 mg/mL (169.34 mM)

DMSO : 25 mg/mL (42.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6934 mL 8.4668 mL 16.9337 mL
5 mM 0.3387 mL 1.6934 mL 3.3867 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMF 1 mM 1.6934 mL 8.4668 mL 16.9337 mL 42.3341 mL
5 mM 0.3387 mL 1.6934 mL 3.3867 mL 8.4668 mL
10 mM 0.1693 mL 0.8467 mL 1.6934 mL 4.2334 mL
15 mM 0.1129 mL 0.5645 mL 1.1289 mL 2.8223 mL
20 mM 0.0847 mL 0.4233 mL 0.8467 mL 2.1167 mL
25 mM 0.0677 mL 0.3387 mL 0.6773 mL 1.6934 mL
30 mM 0.0564 mL 0.2822 mL 0.5645 mL 1.4111 mL
40 mM 0.0423 mL 0.2117 mL 0.4233 mL 1.0584 mL
DMF 50 mM 0.0339 mL 0.1693 mL 0.3387 mL 0.8467 mL
60 mM 0.0282 mL 0.1411 mL 0.2822 mL 0.7056 mL
80 mM 0.0212 mL 0.1058 mL 0.2117 mL 0.5292 mL
100 mM 0.0169 mL 0.0847 mL 0.1693 mL 0.4233 mL
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VP-U-6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VP-U-62361324-80-1Nucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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