2. Cell Cycle/DNA Damage Epigenetics PROTAC
  3. Aurora Kinase Ligands for Target Protein for PROTAC
  4. MK-5108-NH-PEG2-alkyne

MK-5108-NH-PEG2-alkyne is a Aurora kinase A (AURKA) inhibitor. MK-5108-NH-PEG2-alkyne can be used for synthesis of PROTAC AURKA degrader 1 (HY-175830).

For research use only. We do not sell to patients.

MK-5108-NH-PEG2-alkyne

MK-5108-NH-PEG2-alkyne Chemical Structure

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MK-5108-NH-PEG2-alkyne Related Antibodies

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Description

MK-5108-NH-PEG2-alkyne is a Aurora kinase A (AURKA) inhibitor. MK-5108-NH-PEG2-alkyne can be used for synthesis of PROTAC AURKA degrader 1 (HY-175830)[1].

IC50 & Target[1]

Aurora A

 

Molecular Weight

587.11

Formula

C29H32ClFN4O4S
SMILES

FC(C(Cl)=CC=C1)=C1OC(CC2)CCC2(C(NCCOCCOCC#C)=O)CC3=CC=CC(NC4=NC=CS4)=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MK-5108-NH-PEG2-alkyne Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MK-5108-NH-PEG2-alkyneAurora KinaseLigands for Target Protein for PROTACTarget Protein-binding MoietyAurora kinase AAURKAInhibitorinhibitorinhibit

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MK-5108-NH-PEG2-alkyne
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HY-175827
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