2. Immunology/Inflammation Apoptosis
  3. Interleukin Related Apoptosis
  4. Bizaxofusp

Bizaxofusp  (Synonyms: MDNA55; NBI-3001; PRX-321)

Cat. No.: HY-P990708
Technical Support

Bizaxofusp (MDNA55) is a fusion protein formed by the linkage of IL-4 and a truncated Pseudomonas exotoxin. Bizaxofusp can bind to IL-4 receptors on the surface of tumor cells and be internalized, and its exotoxin moiety can inhibit protein synthesis and induce tumor cell apoptosis. Bizaxofusp can be used in the study of cancer.

For research use only. We do not sell to patients.

CAS No. : 1236019-35-4

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Bizaxofusp Related Antibodies

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Description

Bizaxofusp (MDNA55) is a fusion protein formed by the linkage of IL-4 and a truncated Pseudomonas exotoxin. Bizaxofusp can bind to IL-4 receptors on the surface of tumor cells and be internalized, and its exotoxin moiety can inhibit protein synthesis and induce tumor cell apoptosis. Bizaxofusp can be used in the study of cancer[1].

IC50 & Target

IL4R
Clinical Trial
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
CAS No.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • TOXIN_BIG-PROTEIN
Purity & Documentation
References
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Bizaxofusp Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bizaxofusp1236019-35-4MDNA55 NBI-3001 PRX-321MDNA 55MDNA-55NBI3001NBI 3001NBI-3001PRX321PRX 321PRX-321Interleukin RelatedApoptosisILfusion proteinIL-4Inhibitorinhibitorinhibit

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