Search Result

Results for "

anti-inflammatory

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (6) 5 alpha Reductase (1) 5-HT Receptor (27) Acetyl-CoA Carboxylase (1) Acyltransferase (1) ADAMTS (1) ADC Payload (9) Adenosine Deaminase (3) Adenosine Kinase (1) Adenosine Receptor (26) Adenylate Cyclase (1) Adiponectin Receptor (2) Adrenergic Receptor (20) Akt (125) Aldehyde Dehydrogenase (ALDH) (2) Aldose Reductase (7) Amino Acid Derivatives (6) Aminoacyl-tRNA Synthetase (1) Aminopeptidase (8) Aminotransferases (Transaminases) (1) AMPK (37) Amylases (3) Amyloid-β (54) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (8) Angiotensin Receptor (6) Angiotensin-converting Enzyme (ACE) (12) Annexin A (2) Antibiotic (151) Antifolate (1) AP-1 (20) Apolipoprotein (5) Apoptosis (760) Aquaporin (1) Arginase (2) Aryl Hydrocarbon Receptor (8) ASK1 (2) Atg8/LC3 (2) ATM/ATR (2) ATP Synthase (1) ATP-binding cassette (ABC) transporters (1) Aurora Kinase (12) Autophagy (274) Bacterial (463) Bcl-2 Family (33) Bcr-Abl (2) BCRP (1) Beta-lactamase (1) Beta-secretase (2) Biochemical Assay Reagents (73) BMX Kinase (1) Bombesin Receptor (2) Bradykinin Receptor (4) Btk (7) c-Fms (3) c-Kit (1) c-Myc (3) C-type Lectin-like Receptors (CTLRs) (1) Calcineurin (1) Calcium Channel (84) Calmodulin (3) CaMK (3) Cannabinoid Receptor (23) Carbamoyl Phosphate Synthetase (CPS) (1) Carbonic Anhydrase (13) Carboxylesterase (CES) (4) Casein Kinase (6) Caspase (81) CaSR (1) Cathepsin (15) CCR (12) CD28 (1) CDK (22) Ceramidase (3) CFTR (4) Chemerin Receptor (2) Chloride Channel (10) Cholecystokinin Receptor (1) Cholinesterase (ChE) (41) Claudin (1) ClpP (3) CMV (3) Collagen (1) Complement System (6) COX (622) CRAC Channel (1) CRFR (2) Cryptochrome (2) CX3CR1 (1) CXCR (22) Cyclic GMP-AMP Synthase (6) Cyclin G-associated Kinase (GAK) (1) Cytochrome P450 (46) Dengue Virus (5) Deubiquitinase (4) Dihydroorotate Dehydrogenase (8) Dipeptidyl Peptidase (2) Discoidin Domain Receptor (2) DNA Alkylator/Crosslinker (2) DNA Methyltransferase (1) DNA/RNA Synthesis (51) Dopamine Receptor (7) Drug Derivative (30) Drug Intermediate (20) Drug Isomer (8) Drug Metabolite (58) Drug-Linker Conjugates for ADC (2) Dynamin (2) DYRK (4) E-Selectin (1) E1/E2/E3 Enzyme (7) E3 Ligase Ligand-Linker Conjugates (2) EBI2/GPR183 (1) EBV (6) EGFR (9) Elastase (7) Endogenous Metabolite (413) Endoplasmic Reticulum Oxidoreductase 1 (ERO1) (4) Enterovirus (12) Epigenetic Reader Domain (18) Epoxide Hydrolase (14) ERK (96) Estrogen Receptor/ERR (14) Eukaryotic Initiation Factor (eIF) (1) FAAH (10) FABP (5) Factor Xa (4) FAK (10) Farnesyl Transferase (3) Fat Mass and Obesity-associated Protein (FTO) (5) Ferroptosis (43) FGFR (4) Filovirus (2) FLAP (5) Flavivirus (3) FLT3 (8) Fluorescent Dye (10) Formyl Peptide Receptor (FPR) (6) FOXO (4) Free Fatty Acid Receptor (12) Fungal (138) FXR (9) G protein-coupled Bile Acid Receptor 1 (6) GABA Receptor (26) Galectin (1) Gap Junction Protein (8) GHR (1) GHSR (2) GLP Receptor (1) Glucocorticoid Receptor (140) GLUT (12) Glutathione Peroxidase (13) Glutathione S-transferase (8) Glycosidase (17) GlyT (2) GnRH Receptor (1) GPR109A (1) GPR35 (3) GPR4 (1) GPR55 (3) GPR68 (1) GPR84 (5) GSK-3 (30) Guanylate Cyclase (6) HBV (14) HCV (9) HCV Protease (1) HDAC (25) Hedgehog (4) Heme Oxygenase (HO) (13) Herbicide (3) HIF/HIF Prolyl-Hydroxylase (24) Histamine Receptor (66) Histone Acetyltransferase (10) Histone Demethylase (2) Histone Methyltransferase (13) HIV (68) HIV Integrase (1) HIV Protease (9) HMG-CoA Reductase (HMGCR) (5) HPV (1) HSP (14) HSV (14) Huntingtin (2) Hydroxycarboxylic Acid Receptor (HCAR) (4) IAP (2) IFNAR (6) IGF-1R (3) iGluR (9) IKK (38) Imidazoline Receptor (3) Indoleamine 2,3-Dioxygenase (IDO) (6) Influenza Virus (43) Insecticide (4) Insulin Receptor (6) Integrin (22) Interleukin Related (277) IRAK (21) Isotope-Labeled Compounds (286) JAK (48) JNK (79) Keap1-Nrf2 (107) KMO (2) L-Selectin (1) Lactate Dehydrogenase (6) LDLR (2) Leukotriene Receptor (35) Ligands for E3 Ligase (5) Ligands for Target Protein for PROTAC (2) LIM Kinase (LIMK) (1) Lipase (1) Liposome (5) Lipoxygenase (62) LOX-1 (2) LPL Receptor (5) LRRK2 (2) LXR (9) mAChR (12) MAGL (5) MALT1 (1) MAP3K (12) MAP4K (1) MAPKAPK2 (MK2) (7) MARK (1) Mas-related G-protein-coupled Receptor (MRGPR) (2) MDM-2/p53 (25) MEK (9) Melanocortin Receptor (16) Melatonin Receptor (5) mGluR (1) MicroRNA (3) Microtubule/Tubulin (12) Mineralocorticoid Receptor (6) Mitochondrial Metabolism (14) Mitophagy (28) Mixed Lineage Kinase (4) MMP (40) Molecular Glues (3) Monoamine Oxidase (15) mTOR (31) MyD88 (13) Myosin (2) Na+/H+ Exchanger (NHE) (1) Na+/K+ ATPase (2) nAChR (20) NADPH Oxidase (9) NAMPT (1) Necroptosis (5) NEKs (1) Neurokinin Receptor (5) Neuromedin U Receptor (NMUR) (1) NF-κB (522) NO Synthase (243) NOD-like Receptor (NLR) (74) Notch (10) Nuclear Factor of activated T Cells (NFAT) (7) Nuclear Hormone Receptor 4A/NR4A (10) Nucleoside Antimetabolite/Analog (11) OAT (1) Oct3/4 (1) Opioid Receptor (25) Organoid (3) Ornithine decarboxylase (ODC) (1) Orphan Receptor (1) Oxidative Phosphorylation (5) Oxytocin Receptor (3) P-glycoprotein (14) P-selectin (3) P2X Receptor (13) P2Y Receptor (14) p38 MAPK (212) p62 (3) PAI-1 (1) Pantetheinase (1) Parasite (149) PARP (27) PCSK9 (2) PD-1/PD-L1 (6) PDGFR (2) PERK (22) PGC-1α (4) PGE synthase (42) Phosphatase (25) Phosphodiesterase (PDE) (87) Phospholipase (29) Phytohormone (2) PI3K (72) Pim (5) PKA (13) PKC (23) PKD (3) Platelet-activating Factor Receptor (PAFR) (5) Polo-like Kinase (PLK) (1) Potassium Channel (44) PPAR (74) Procollagen C Proteinase (1) Progesterone Receptor (2) Prolyl Endopeptidase (PREP) (2) Prostaglandin Receptor (59) PROTACs (8) Protease Activated Receptor (PAR) (3) Proteasome (8) Protein Arginine Deiminase (1) Proton Pump (5) PTEN (3) Pyroptosis (20) Pyruvate Kinase (2) Quinone Reductase (2) RAD51 (2) Raf (1) RANKL/RANK (7) RAR/RXR (10) Ras (7) Reactive Oxygen Species (ROS) (297) Reference Standards (788) Renin (1) Reverse Transcriptase (4) Ribosomal S6 Kinase (RSK) (4) RIP kinase (8) ROCK (6) ROR (8) ROS Kinase (11) RSV (4) RXFP Receptor (1) S100 Protein (2) Salt-inducible Kinase (SIK) (3) SARS-CoV (54) Ser/Thr Protease (10) Serotonin Transporter (1) Sex Pheromone (3) SGK (2) SGLT (3) Sigma Receptor (9) Sirtuin (14) Small Interfering RNA (siRNA) (2) Smo (2) SOD (36) Sodium Channel (16) Somatostatin Receptor (6) SphK (4) Src (9) STAT (68) Stearoyl-CoA Desaturase (SCD) (3) STING (12) Succinate Dehydrogenase (2) Survivin (3) Syk (8) TAM Receptor (2) Taste Receptor (4) Tau Protein (9) Telomerase (2) TGF-beta/Smad (29) TGF-β Receptor (10) Thrombin (4) Thrombopoietin Receptor (3) Thyroid Hormone Receptor (2) Tim3 (2) TNF Receptor (202) Toll-like Receptor (TLR) (78) Topoisomerase (18) Transmembrane Glycoprotein (5) Transthyretin (TTR) (2) TREM receptor (2) Trk Receptor (5) TRP Channel (31) Tyrosinase (19) UGT (2) URAT1 (1) Urea Transporter (1) Urotensin Receptor (1) VAP-1 (2) Vasopressin Receptor (4) VD/VDR (4) VEGFR (11) Virus Protease (27) Wnt (20) Xanthine Oxidase (20) α-synuclein (6) β-catenin (13) β-glucuronidase (4) γ-secretase (2)
By Research Areas:	Cancer (1518) Cardiovascular Disease (430) Endocrinology (195) Infection (774) Inflammation/Immunology (3810) Metabolic Disease (467) Neurological Disease (785)
Click Chemistry:	Azide (4) Alkynes (14)
Oligonucleotides:	Solvents (2) Preservatives (1) Nucleosides and their Analogs (5) Decoy ODNs (1) Nucleoside Phosphoramidites (2) saRNAs (2) I (6) Solubilizing Agents (1) Phospholipids (4) siRNA drugs (2) Antisense Oligonucleotides (3) Cholesterol (2) siRNAs (2) Antioxidants (2) Emulsifiers (3) Polymers (1) Chelating Agents (2)

4515

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

134

Peptides

Inhibitory Antibodies

1900

Natural
Products

377

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148553

Anti-inflammatory agent 36	Others	Inflammation/Immunology
Anti-inflammatory agent 36 is an anti-inflammatory agent. Anti-inflammatory agent 36 inhibits LPS-induced macrophage activation .

HY-150156

Anti-inflammatory agent 32	Others	Inflammation/Immunology
Anti-inflammatory agent 32 (compound C3) has anti-oxidative and anti-inflammatory activity. Anti-inflammatory agent 32 can be used for skin care products research and development .

HY-147769

Anti-inflammatory agent 23	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 23 (Compound 4m) is an anti-inflammatory agent. Anti-inflammatory agent 23 inhibits the production of NO activated by LPS with an IC₅₀ of 0.449 μM. Anti-inflammatory agent 23 has a good affinity for p65 protein .

HY-156340

Anti-inflammatory agent 58	Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 58 is an anti-inflammatory agent. Anti-inflammatory agent 58 inhibits IL-1β with an IC₅₀ of 1.08 μM. Anti-inflammatory agent 58 decreases pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation .

HY-156342

Anti-inflammatory agent 59	Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 59 is an anti-inflammatory agent. Anti-inflammatory agent 58 inhibits IL-1β with an IC₅₀ of 2.28 μM. Anti-inflammatory agent 58 decreases pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation .

HY-N8862

Anti-inflammatory agent 69	Others	Inflammation/Immunology
Anti-inflammatory agent 69 (compound 12), sesquiterpenoid, is an anti-inflammatory agent isolated from the dried flower buds of Tussilago farfara. Anti-inflammatory agent 69 can inhibit the NO production with IC₅₀ value of 24 μM .

HY-143410

Anti-inflammatory agent 16	TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 16 (compound 14), a peptidomimetic, shows potent anti-inflammatory activity. Anti-inflammatory agent 16 reduces TNFα, NO, CD40 and CD86 expression level .

HY-146435

Anti-inflammatory agent 22	TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC₅₀ value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice .

HY-146547

Anti-inflammatory agent 17	Interleukin Related TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 17 is a potent and orally active anti-inflammatory agent. Anti-inflammatory agent 17 inhibits the release of IL-6 and TNF-α in vitro experiments without cytotoxicity. Anti-inflammatory agent 17 exhibits anti-inflammatory activity in vivo. Anti-inflammatory agent 17 has the potential for the research of Acute lung injury (ALI) .

HY-N15335

Anti-inflammatory agent 98	Drug Derivative	Inflammation/Immunology
Anti-inflammatory agent 98 (Compound 8) is a potent NO production inhibitor with an IC₅₀ value of 14.79 μM. Anti-inflammatory agent 98 is a benzofuran with anti-inflammatory activities, which is found in the roots of Paeonia lactiflora Pall .

HY-N12101

Anti-inflammatory agent 57	Others	Inflammation/Immunology
Anti-inflammatory agent 57 (Compound 13), pyranocoumarin, is a nature product. Anti-inflammatory agent 57 can be isolated from the roots of Peucedanum praeruptorum. Anti-inflammatory agent 57 has multidrug-resistance (MDR) reversal and anti-inflammatory effect .

HY-162425

Anti-inflammatory agent 78	PGE synthase COX	Inflammation/Immunology Cancer
Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. Anti-inflammatory agent 78 has significant potency on PGE2, PGE1, COX-2 and COX-1 inhibition. Anti-inflammatory agent 78 can inhibits NO release in LPS-stimulated RAW 264.7 cell line .

HY-156431

Anti-inflammatory agent 61	TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 61 (Compound 5b) is a potent anti-inflammatory agent. Anti-inflammatory agent 61 reduces TNF-α expression in LPS-induced inflammation in RAW 264.7 cells. Anti-inflammatory agent 61 alleviates APAP-induced inflammation in HepG2 cells .

HY-155997

Anti-inflammatory agent 56	COX	Inflammation/Immunology
Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor (IC₅₀: 0.54 μM). Anti-inflammatory agent 56 has anti-oxidant and anti-inflammatory effects. Anti-inflammatory agent 56 inhibits oxidative stress induced cell death. Anti-inflammatory agent 56 inhibits oxidative stress and neuroinflammation by inhibiting Keap1, COX-2 and iNOS. Anti-inflammatory agent 56 has low acute toxicity in mice (LD₅₀: 1000 mg/kg) .

HY-146971

Anti-inflammatory agent 38	NO Synthase Reactive Oxygen Species (ROS)	Inflammation/Immunology
Anti-inflammatory agent 38 (compound 23d) is a potent Nrf2/HO-1 pathway inhibitor, with an IC₅₀ value of 0.38 μM for NO. Anti-inflammatory agent 38 can significantly reduce the level of ROS in cells. Anti-inflammatory agent 38 can be used for researching anti-inflammatory .

HY-162170

Anti-inflammatory agent 72	NF-κB Keap1-Nrf2 p38 MAPK	Inflammation/Immunology
Anti-inflammatory agent 72 (compound 5) is a novel resveratrol derivative hybrid with benzoylhydrazine. Anti-inflammatory agent 72 shows anti-inflammatory and antioxidant activities by activating Nrf2 and inhibiting NF-κB p65/iNOS and MAPKs signaling pathways .

HY-149961

Anti-inflammatory agent 40	Parasite	Infection Inflammation/Immunology
Anti-inflammatory agent 40 is a potential and orally active anti-malarial and anti-inflammatory agent. Anti-inflammatory agent 40 inhibits carrageenan induced paw swelling in vivo.

HY-161757

Anti-inflammatory agent 86	Drug Derivative	Inflammation/Immunology
Anti-inflammatory agent 86 is a Chrysin (HY-14589) derivative with anti-inflammatory effects. Anti-inflammatory agent 86 inhibits monocyte adhesion to colon epithelium induced by TNF-α, with an IC₅₀ of 4.71 μM. Anti-inflammatory agent 86 has the potential for the inflammatory bowel disease (IBD) research .

HY-155551

Anti-inflammatory agent 46	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 46 (compound 7h) is an anti-inflammatory agent with nitric oxide (NO) inhibitory effect. Anti-inflammatory agent 46 binds to iNOS with low energies, inhibits swelling in mice (at dose of 10 mg/kg) .

HY-148456

Anti-inflammatory agent 34	Others	Inflammation/Immunology
Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent .

HY-149724

Anti-inflammatory agent 65	STING NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 65 (compound 29) is a Hederagonic acid derivative with potent anti-inflammatory activity. Anti-inflammatory agent 65 inhibits nitric oxide (NO) release. Anti-inflammatory agent 65 inhibits the nuclear translocation of IRF3 and p65, and disrupts the STING/IRF3/NF-κB signaling pathway, thereby attenuating the inflammatory response .

HY-155405

Anti-inflammatory agent 64	ROS Kinase Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 64 (compound 4b) inhibits the secretion of IL-6 and TNF-α. Anti-inflammatory agent 64 has antioxidant and anti-inflammatory activity in vitro and in vivo. Anti-inflammatory agent 64 can effectively reduce paw edema .

HY-149671

Anti-inflammatory agent 63	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 63 is an anti-inflammatory agent that shows optimal inhibitory activity (EC₅₀ = 5.33±0.57 μM) against the production of nitric oxide (NO) induced by lipopolysaccharide (LPS) in RAW264.7 cells .

HY-155646

Anti-inflammatory agent 48	NF-κB	Inflammation/Immunology
Anti-inflammatory agent 48 is an anti-inflammatory agent based on its role in inhibiting the NF-κB signaling pathway and activating HO-1 expression .

HY-162168

Anti-inflammatory agent 71	COX	Inflammation/Immunology
Anti-inflammatory agent 71 (Compound 3.2) is an anti-inflammatory agent that can reduce the levels of neutrophils, COX-2, nitrotyrosine, IL-1b, and C-reactive protein, while increasing the level of eNOS .

HY-155753

Anti-inflammatory agent 50	NF-κB COX	Inflammation/Immunology
Anti-inflammatory agent 50 (compound a1) is a Fusidic acid derivative with anti-inflammatory effects. Anti-inflammatory agent 50 inhibits inflammatory factor NO, IL-6 and TNF-α. Anti-inflammatory agent 50 alleviates acute lung injury by regulating inflammatory mediators and suppressing the MAPK, NF-κB and NLRP3 inflammasome signaling pathways .

HY-173416

Anti-inflammatory agent 100	NF-κB p38 MAPK ERK JNK	Inflammation/Immunology
Anti-inflammatory agent 100 (Compound (+)-4S-23) is an anti-inflammatory agent. Anti-inflammatory agent 100 inhibits MAPK and NF-κB signaling, and also inhibits NF-κB pathway by suppressing the phosphorylation of IκB-α and blocking nuclear translocation of phosphorylated p65. Anti-inflammatory agent 100 inhibits NO production (IC₅₀: 0.5 μM) and TNF-α, IL-6, IL-1β secretion .

HY-155765

Anti-inflammatory agent 51	NF-κB	Inflammation/Immunology
Anti-inflammatory agent 51 (compound 11d) is an amide/sulfonamide derivative with anti-inflammatory activities. Anti-inflammatory agent 51 inhibits NF-κB activation, has the potential for acute lung injury and ulcerative colitis research .

HY-150587

Anti-inflammatory agent 31	ERK NF-κB	Inflammation/Immunology
Anti-inflammatory agent 31 (enone 17) is a kind of andrographolide derivatives, is a *anti-inflammatory* agent. Anti-inflammatory agent 31 inhibits NF-κB activation by upstream blockade of PI3K/Akt and ERK1/2 MAPK activation. Anti-inflammatory agent 31 shows recovery effective of the intracellular GSH levels and protective effect on liver .

HY-163116

Anti-inflammatory agent 67	COX Carbonic Anhydrase	Neurological Disease Inflammation/Immunology
Anti-inflammatory agent 67 (compound 7a) is a dual inhibitor of carbonic anhydrase and COX-2, a sulfonamide derivative of Polmacoxib (HY-16726), and has anti-inflammatory properties and analgesic activity. Anti-inflammatory agent 67 has IC₅₀s of 10.4 μM and 50 nM for COX-1 and COX-2, respectively. The Ki of anti-inflammatory agent 67 binding to different isoforms of carbonic anhydrase are 48.3 nM (CA I), 42.2 nM (CA II), 52.3 nM (CA IX), and 13.3 nM (CA XII) .

HY-163117

Anti-inflammatory agent 68	COX Carbonic Anhydrase	Neurological Disease Inflammation/Immunology
Anti-inflammatory agent 68 (compound 7b) is a dual inhibitor of carbonic anhydrase and COX-2, a sulfonamide derivative of Polmacoxib (HY-16726), with anti-inflammatory properties and analgesic activity. Anti-inflammatory agent 68 has IC₅₀s of 12.6 μM and 60 nM for COX-1 and COX-2, respectively. The Ki of anti-inflammatory agent 68 binding to different isoforms of carbonic anhydrase are 52.6 nM (CA I), 79.1 nM (CA II), 58.1 nM (CA IX), and 17.2 nM (CA XII) .

HY-146421

Anti-inflammatory agent 21	NO Synthase NF-κB Reactive Oxygen Species (ROS)	Inflammation/Immunology
Anti-inflammatory agent 21 (compound 9o) is an orally active and low cytotoxic anti-inflammatory agent, with an IC₅₀ value of 0.76 μM for NO. Anti-inflammatory agent 21 acts via accumulation ROS and blocks the NF-κB/MAPK signaling pathway. Anti-inflammatory agent 21 can ameliorate cartilage destruction and inflammatory cell infiltration in arthritis rats model .

HY-155821

Anti-inflammatory agent 55	NF-κB NO Synthase TNF Receptor Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 55 (compound 9j) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC₅₀: 0.8 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model .

HY-155820

Anti-inflammatory agent 54	NF-κB NO Synthase TNF Receptor Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 54 (compound 9c) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC₅₀: 2.4 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model .

HY-146419

Anti-inflammatory agent 20	NF-κB COX TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 20 (compound 5a) is a potent inhibitor of NO activity. Anti-inflammatory agent 20 shows anti-inflammatory activity. Anti-inflammatory agent 20 suppresses LPS-induced inflammation via inhibiting the activation of NF-κB and MAPK signaling and thereby reducing IL-6, TNF-α, iNOS, and COX-2 upregulation .

HY-168369

Anti-inflammatory agent 94	Cannabinoid Receptor	Neurological Disease Inflammation/Immunology
Anti-inflammatory agent 94 (compound 4b) is a potent cannabinoid ligand with K_is of 29 nM and 8 nM against CB2 and CB1. Anti-inflammatory agent 94 can be utilized in inflammation rersearch .

HY-144737

Anti-inflammatory agent 15	Bacterial TNF Receptor	Infection Inflammation/Immunology
Anti-inflammatory agent 15 (compound 29) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 15 inhibits Mtb H37Rv and M299 growth, with MIC₅₀ (minimum inhibitory concentration 50%) of 2.3 and 7.8 μM, respectively. Anti-inflammatory agent 15 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 15 can be used for tuberculosis (TB) research .

HY-144727

Anti-inflammatory agent 11	Bacterial TNF Receptor	Infection Inflammation/Immunology
Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 11 inhibits Mtb H37Rv and M299 growth, with MIC₅₀ (minimum inhibitory concentration 50%) of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 11 can be used for tuberculosis (TB) research .

HY-163775

Anti-inflammatory agent 88	MyD88 NF-κB	Inflammation/Immunology
Anti-inflammatory agent 88 (compound 6) is a carbazole derivative with anti-inflammatory activity found in marine Streptomyces. It exerts its anti-inflammatory effect by inhibiting pro-inflammatory factors and enhancing the expression of anti-inflammatory factors in the Myd88/Nf-κB pathway. Anti-inflammatory agent 88 can be used for the development of anti-inflammatory drugs .

HY-155780

Anti-inflammatory agent 52	COX	Inflammation/Immunology
Anti-inflammatory agent 52 (compound 7j) is an orally active selective COX-2 inhibitor. Anti-inflammatory agent 52 has anti-HT29 transfer activity, which leads to periodic arrest in G2/M phase. Anti-inflammatory agent 52 has safety, moderate ability to suppress inflammation. Anti-inflammatory agent 52 has a rare property of suppressing the development of tumor in mouse model, showing anti-cancer activity .

HY-173504

Anti-inflammatory agent 101	Others	Inflammation/Immunology
Anti-inflammatory agent 101 (Compound C04) is an orally active anti-inflammatory agent. Anti-inflammatory agent 101 has significant anti-lipid accumulation, anti-inflammatory and anti-fibrotic activities. Anti-inflammatory agent 101 works by reducing fatty acid uptake, stimulating fatty acid oxidation and alleviating inflammation. Anti-inflammatory agent 101 can be used in the study of NASH and its related liver fibrosis .

HY-155781

Anti-inflammatory agent 53	COX	Inflammation/Immunology
Anti-inflammatory agent 53 (compound 7c) is an orally active selective COX-2 inhibitor. Anti-inflammatory agent 52 has anti-HT29 transfer activity, which leads to periodic arrest in S phase and G2/M phase. Anti-inflammatory agent 52 has safety, moderate ability to suppress inflammation. Anti-inflammatory agent 52 has a rare property of suppressing the development of tumor in mouse model, showing anti-cancer activity .

HY-151921

Anti-inflammatory agent 33	p38 MAPK	Inflammation/Immunology
Anti-inflammatory agent 33 is a potent p38α inhibitor. Anti-inflammatory agent 33 inhibits NO production. Anti-inflammatory agent 33 inhibits LPS-induced iNOS, COX-2, p-p38α, p-MK2 protein expression. Anti-inflammatory agent 33 shows anti-inflammatory activity .

HY-159157

Anti-inflammatory agent 92	STAT	Inflammation/Immunology
Anti-inflammatory agent 92 (compound LD4) is a porphyrin derivative. Anti-inflammatory agent 92 has anti-inflammatory properties. Anti-inflammatory agent 92 can alleviate ulcerative colitis by inhibiting the STAT3-EPHX2 axis .

HY-156436

Anti-inflammatory agent 62	Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 62 is an anti-inflammatory agent. Anti-inflammatory agent 62 alleviate Acetaminophen-induced hepatotoxicity in HepG2 by the regulation of inflammatory and oxidative stress pathways .

HY-172871

Anti-inflammatory agent 102	MAP3K p38 MAPK NF-κB Reactive Oxygen Species (ROS) NO Synthase Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 102 (Compound 11a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 102 exerts its anti-inflammatory effect by blocking the activation of the ASK1/p38 MAPKs/NF-κB signaling pathway. Anti-inflammatory agent 102 has significant anti-inflammatory activity and can inhibit the release of NO, ROS, and inflammatory factors (such as IL-6, TNF-α, IL-1β). Anti-inflammatory agent 102 can be used in the study of inflammatory diseases such as ulcerative colitis (UC) .

HY-111473

Anti-inflammatory agent 82	Others	Inflammation/Immunology
Anti-inflammatory agent 82 has potential analgesic and anti-inflammatory effects .

HY-143456

Anti-inflammatory agent 18	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 18 (compound 3b) shows NO inhibitory activity, with an IC₅₀ of 15.94 μM. Anti-inflammatory agent 18 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 18 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .

HY-143457

Anti-inflammatory agent 19	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 19 (compound 2b) shows NO inhibitory activity, with an IC₅₀ of 36.00 μM. Anti-inflammatory agent 19 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 19 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .

HY-N10436

Anti-inflammatory agent 30	Others	Metabolic Disease Inflammation/Immunology
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8862

Anti-inflammatory agent 69	Structural Classification Terpenoids Sesquiterpenes Source classification Dracocephalum tanguticum Maxim. Plants Compositae	Others
Anti-inflammatory agent 69 (compound 12), sesquiterpenoid, is an anti-inflammatory agent isolated from the dried flower buds of Tussilago farfara. Anti-inflammatory agent 69 can inhibit the NO production with IC₅₀ value of 24 μM .

HY-N15335

Anti-inflammatory agent 98	Structural Classification Natural Products Paeonia lactiflora Pall. Source classification Plants Paeoniaceae	Drug Derivative
Anti-inflammatory agent 98 (Compound 8) is a potent NO production inhibitor with an IC₅₀ value of 14.79 μM. Anti-inflammatory agent 98 is a benzofuran with anti-inflammatory activities, which is found in the roots of Paeonia lactiflora Pall .

HY-N12101

Anti-inflammatory agent 57	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Anti-inflammatory agent 57 (Compound 13), pyranocoumarin, is a nature product. Anti-inflammatory agent 57 can be isolated from the roots of Peucedanum praeruptorum. Anti-inflammatory agent 57 has multidrug-resistance (MDR) reversal and anti-inflammatory effect .

HY-N10436

Anti-inflammatory agent 30	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 30 (Compound 5) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10435

Anti-inflammatory agent 29	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 29 (Compound 7) is an anti-inflammatory agent with hepatoprotective activity .

HY-N10434

Anti-inflammatory agent 28	Source classification Phenols Dicerothamnus rhinocerotis Plants Umbelliferae	Others
Anti-inflammatory agent 28 (Compound 9) is an anti-inflammatory agent with hepatoprotective activity .

HY-N11796

Anti-inflammatory agent 44	Structural Classification Flavonoids Flavones Source classification Phenols Polyphenols Aizoaceae Plants Tetragonia tetragonioides (Pall.) Kuntze	Biochemical Assay Reagents
Anti-inflammatory agent 44 (compound 1) is a 6-methoxyflavonol glycoside, with anti-inflammatory activity. Anti-inflammatory agent 44 can be isolated from the aerial parts of Tetragonia tetragonoides .

HY-N11788

Anti-inflammatory agent 43	Structural Classification Flavonoids Flavones Source classification Aizoaceae Plants Tetragonia tetragonioides (Pall.) Kuntze	Biochemical Assay Reagents
Anti-inflammatory agent 43 (compound 3) is a 6-methoxyflavonol glycoside, with anti-inflammatory activity. Anti-inflammatory agent 44 can be isolated from the aerial parts of Tetragonia tetragonoides .

HY-N12817

Anti-inflammatory agent 80	Apocynaceae Structural Classification Cardiacglycosides Source classification Vincetoxicum forrestii (Schltr.) C. Y. Wu & D. Z. Li Plants Steroids	NO Synthase
Anti-inflammatory agent 80 (Compound 2/2f) is an anti-inflammatory agent and has anti-tumor activity. Anti-inflammatory agent 80 can be isolated fromCynanchum limprichtiiSchltr .

HY-N10066

Anti-inflammatory agent 5	Structural Classification Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Inflammation/Immunology Disease Research Fields	NO Synthase
Anti-inflammatory agent 5 displays potent inhibition of NO generation in lipopolysaccharide-induced BV-2 microglial cells.

HY-N12615

Anti-inflammatory agent 75	Structural Classification Ketones, Aldehydes, Acids Source classification Hypericaceae Plants Hypericum henryi H. Lév. & Vaniot	Others

HY-N9971

Hentriacontane	Structural Classification Natural Products Ficus benghalensis L. Source classification Plants Moraceae	NF-κB Bacterial
Hentriacontane is a long-chain alkane. Hentriacontane exerts anti-inflammatory effects by inhibiting the NF-κB pathway. Hentriacontane has anti-inflammatory, antitumor and antibacterial activities .

HY-N0948A

(+)-Rhododendrol (S)-(+)-Rhododendrol; (+)-Betuligenol	Structural Classification Monophenols Source classification Sapindaceae Phenols Plants Acer nikoense Maxim.	NO Synthase
(+)-Rhododendrol ((S)-(+)-Rhododendrol) is an anti-inflammatory agent that can suppress NO production .

HY-119627

Cajucarinolide	Structural Classification Terpenoids Source classification Croton cajucara Benth. Diterpenoids Euphorbiaceae Plants	Others
Cajucarinolide is anti-Inflammatory diterpene that can be isolated from Croton cajucara .

HY-14579

(+)-Isolariciresinol (+)-Cyclolariciresinol	other families Classification of Application Fields Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology	Others
(+)-Isolariciresinol ((+)-Cyclolariciresinol) can be used for the research of rheumatitis. Anti-inflammatory activity .

HY-N2516

Ginsenoside Rd2	Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Inflammation/Immunology Araliaceae	Others
Ginsenoside Rd2 is a saponin found in Panax japonicus with anti-inflammatory actions .

HY-N8534

Neophytadiene	Cardiovascular Disease other families Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields	Others
Neophytadiene is a diterpene found in Turbinaria ornate, with anti-inflammatory antioxidant and cardioprotective properties .

HY-N7903

Complanatoside B	Flavonols Structural Classification Monophenols Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Plants Astragalus complanatus Bunge var. eutrichus Hand.-Mazz. Inflammation/Immunology Disease Research Fields	Others
Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects .

HY-17463

Prednisolone 5+ Cited Publications	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Glucocorticoid Receptor Endogenous Metabolite
Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research .

HY-N0559

Kirenol	Structural Classification Terpenoids Source classification Bituminaria morisiana (Pignatti & Metlesics) Greuter Diterpenoids Plants Compositae	Others
Kirenol is isolated from Siegesbeckia orientalis with anti-inflammatory and analgesic activity .

HY-N8415

Hispanone	Structural Classification Erythrophleum fordii Oliv. Terpenoids Labiatae Source classification Diterpenoids Plants	Others
Hispanone, a diterpenoidcan, has anti-inflammatory activity. Hispanone can be isolated from Leonurus heterophyllus .

HY-N9971R

Hentriacontane (Standard)	Structural Classification Natural Products Ficus benghalensis L. Source classification Plants Moraceae	Reference Standards NF-κB Bacterial
Hentriacontane (Standard) is the analytical standard of Hentriacontane. This product is intended for research and analytical applications. Hentriacontane is a long-chain alkane. Hentriacontane exerts anti-inflammatory effects by inhibiting the NF-κB pathway. Hentriacontane has anti-inflammatory, antitumor and antibacterial activities .

HY-N7976

Quercetin 3-O-neohesperidoside	Flavonols Flavonoids Classification of Application Fields Verbenaceae Callicarpa bodinieri Levl. Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
Quercetin 3-O-neohesperidoside, a flavonoid glycoside, has anti-inflammatory activity .

HY-N9503

Carvacryl acetate	Structural Classification Natural Products Labiatae Source classification Launaea mucronata (Forssk.) Muschl. Plants	Others
Carvacryl acetate is a leaf oil with anti-inflammatory and antioxidant activity .

HY-N11969

Aquilarone B	Structural Classification Natural Products Thymelaeaceae Source classification Plants Aquilaria sinensis (Lour.) Spreng.	Others
Aquilarone B is a chromone derivative with anti-inflammatory effects .

HY-N1965

Gaultherin	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Gaultheria yunnanensis Ericaceae Plants Inflammation/Immunology Disease Research Fields	Others
Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin .

HY-N9493

Chrysanthemol Chrysanthemyl alcohol	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Compositae Crotalaria juncea L.	Others
Chrysanthemol is a eudesmane type sesquiterpene that can be isolated from Chrysanthemum indicum. Chrysanthemol has anti-inflammatory activity .

HY-N9694

Essential oils, Melaleuca alternifolia	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	Bacterial
Essential oils, Melaleuca alternifolia is extracted from the leaves of Melaleuca alternifolia, has bactericidal and anti-inflammatory activies .

HY-122267A

cis-Clovamide	Structural Classification other families Classification of Application Fields Other Alkaloids Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Apoptosis
cis-Clovamide, a natural phenolic compound with antioxidant, anti-inflammatory and antiapoptotic activities .

HY-N2854

α-Viniferin (+)-α-Viniferin	other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Endogenous Metabolite
α-Viniferin is an anti-inflammatory compound from Caragana chamlagu root .

HY-N15639

Patrinoside	Structural Classification Sambucus ebulus L. Viburnaceae Source classification Plants Saccharides Monosaccharides	Others
Patrinoside is an iridoid glucoside. Patrinoside has choleretic, anti-inflammatory and antispasmodic activities .

HY-135164

Lonchocarpic acid	Structural Classification Leguminosae Derris scandens Source classification Coumarins Phenylpropanoids Plants	Insecticide
Lonchocarpic acid has an anti-inflammatory mechanism of lonchocarpine in LPS- or poly(I:C)-induced neuroinflammation .

HY-N10210

Saccharothrixin F	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Bacterial
Saccharothrixin F is a highly oxygenated saccharothrixin, with antibacterial and anti-inflammatory activities .

HY-N2035

Moslosooflavone	Structural Classification Andrographis paniculata (Burm. F.) Nees Classification of Application Fields Flavones Source classification Plants Medicago × varia Martyn Monophenols Flavonoids Acanthaceae Labiatae Phenols Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species (ROS)
Moslosooflavone is a flavonoid isolated from Andrographis paniculata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities .

HY-N9834

Aureusidin	Cyperus glomeratus L. Flavonoids Classification of Application Fields Source classification Cyperaceae Phenols Polyphenols Plants Other Flavonoids Disease Research Fields Inflammation/Immunology	Lipoxygenase Reactive Oxygen Species (ROS)
Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects .

HY-N1089

Vincosamide	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Classification of Application Fields Source classification Rubiaceae Plants Disease Research Fields Inflammation/Immunology Indole Alkaloids	Cholinesterase (ChE)
Vincosamide, an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity .

HY-116015

Dihomo-γ-Linolenic acid methyl ester	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Dihomo-γ-Linolenic acid methyl ester is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects .

HY-B1320

Meclofenamic acid sodium 5+ Cited Publications Meclofenamate sodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	Gap Junction Protein Endogenous Metabolite Fat Mass and Obesity-associated Protein (FTO)
Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities .

HY-N0940

Batatasin I	Structural Classification Natural Products Monophenols other families Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Bacterial
Batatasin I is a natural product that can be isolated from tuberous roots of Dioscorea batatas, with antifungal activity and anti-inflammatory effects .

HY-137583

Peltatoside	Structural Classification Flavonoids Flavones Source classification Plants Caryophyllaceae Dianthus caryophyllus L.	Others
Peltatoside is a flavone which can be extracted from Annona crassilfora Mart, with an anti-inflammatory activity and can be used for relative research .

HY-N1246

Savinin (-)-Savinin	Structural Classification Natural Products Cupressaceae Juniperus chinensis L. Source classification Plants	Others
Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect .

HY-N15512

Harzianol L	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	NO Synthase
Harzianol L is found in Trichoderma sp. SCSIOW21. Harzianol L can inhibit the production of NO and exhibit anti-inflammatory activity .

HY-N15511

Harzianol A	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	NO Synthase
Harzianol A is found in Trichoderma sp. SCSIOW21. Harzianol A can inhibit the production of NO and exhibit anti-inflammatory activity .

HY-125670

Lanceolarin	Structural Classification Flavonoids Leguminosae Andira inermis (W.Wright) DC. Source classification Plants Isoflavones	Reactive Oxygen Species (ROS)
Lanceolarin is an isoflavone compound isolated from the Andira inermis plant with anti-inflammatory, antioxidant and anti-tumor activities .

HY-N10454

Sinulatumolin C	Other Terpenoids Animals Source classification	TNF Receptor
Sinulatumolin C (compound 3) is an anti-inflammatory agent. Sinulatumolin C has significant TNF-α inhibitory activity with an IC₅₀ value of 2.6 μM .

HY-N10453

Sinulatumolin D	Other Terpenoids Animals Source classification	TNF Receptor
Sinulatumolin D (compound 4) is an anti-inflammatory agent. Sinulatumolin D has significant TNF-α inhibitory activity with an IC₅₀ value of 5.5 μM .

HY-N7643

Comanthoside B	Flavonoids Monophenols other families Classification of Application Fields Flavones Source classification Phenols Plants Disease Research Fields Inflammation/Immunology	Bacterial
Comanthoside B is a flavonoid glycoside isolated from the aerial portions of Ruellia tuberosa L. Comanthoside B has anti-inflammatory and antiseptic activities .

HY-N1253

Scoparinol Scopadiol	Structural Classification Terpenoids Source classification Scrophulariaceae Diterpenoids Scoparia dulcis L Plants	Others
Scoparinol (Scopadiol) is a diterpene isolated from Scoparia dulcis that has significant analgesic and anti-inflammatory activities .

HY-N12525

Bartsioside	Structural Classification Iridoids Terpenoids Source classification Cistanche deserticola Ma Orobanchaceae Plants	Others
Bartsioside is an anti-inflammatory agent which can be extracted from C. deserticola. Bartsioside exerts no significant cytotoxicity under 40 μM to BV-2 cells .

HY-N3693

De-4′-O-methylyangambin	Structural Classification Source classification Lignans Rutaceae Phenylpropanoids Plants Zanthoxylum armatum DC.	Others
De-4’-O-methylyangambin is a lignan that can be isolated from Z. armatum. lignans are reported to has anti-inflammatory activity .

Cat. No.	Product Name	Chemical Structure

HY-B0580S

Ketorolac-d5
Ketorolac-d₅ is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC₅₀s of 20 nM for COX-1 and 120 nM for COX-2 .

HY-B0289S2

Erdosteine-d4
Erdosteine-d₄ is a deuterium labeled Erdosteine (HY-B0289). Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects .

HY-144024S

5-PAHSA-d9
5-PAHSA-d9 is the deuterium labeled 5-PAHSA (HY-116193). 5-PAHSA is a kind of anti-inflammatory and antidiabetic lipokines that connect glucose and lipid metabolism .

HY-B1137S

Ramifenazone-d7
Ramifenazone-d₇ is the deuterium labeled Ramifenazone. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .

HY-B0214S2

Prednisone-d4
Prednisone-d₄ is deuterated labeled Prednisone (HY-B0214). Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus .

HY-B0634S

Aceclofenac-d4
Aceclofenac-d₄ is the deuterium labeled Aceclofenac. Aceclofenac is an orally active nonsteroidal anti-inflammatory agent (NSAID), with analgesic and anti-inflammatory properties. Aceclofenac is used for the research of osteoarthritis, ankylosing spondylitis, rheumatoid arthritis .

HY-153701S

Envudeucitinibum
Envudeucitinibum (Envudeucitinib) is a Janus kinase inhibitor, with anti-inflammatory effect .

HY-10448S4

Capsaicin-d7
Capsaicin-d₇ is deuterated labeled Capsaicin (HY-10448). Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects .

HY-17463S

Prednisolone-d8
Prednisolone-d₈ is the deuterium labeled Prednisolone. Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research .

HY-17361S

Etofenamate-d4
Etofenamate-d₄ is the deuterium labeled Etofenamate. Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases .

HY-B1203S

Fludrocortisone-d5
Fludrocortisone-d₅ is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

HY-B1203S1

Fludrocortisone-d2
Fludrocortisone-d₂ is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

HY-B0808S

Oxaprozin-d4
Oxaprozin-d₄ is the deuterium labeled Oxaprozin, which is a non-steroidal anti-inflammatory agent (NSAID).

HY-W756637

Ibufenac-13C6
Ibufenac- ¹³C₆ (Dytransin- ¹³C₆) is the ¹³C-labeled Ibufenac (HY-W040672). Ibufenac (Dytransin) is an orally active nonsteroidal anti-inflammatory agent. Ibufenac exerts anti-inflammatory, analgesic and antipyretic effects. Ibufenac is being studied for the treatment of rheumatic diseases such as rheumatoid arthritis .

HY-B0363S

Nimesulide-d5
Nimesulide-d₅ is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC₅₀s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC₅₀ >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties .

HY-15029S

(±)-Naproxen-d3
(±)-Naproxen-d₃ is the deuterium labeled (±)-Naproxen. (±)-Naproxen is a non-steroidal anti-inflammatory drug (NSAID) .

HY-13571S

Betamethasone dipropionate-d10
Betamethasone dipropionate-d₁₀ is the deuterium labeled Betamethasone dipropionate. Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.

HY-132405S

Desmethyl Naproxen-d3
Desmethyl Naproxen-d₃ is deuterium labeled Desmethyl Naproxen. Desmethyl Naproxen is the metabolite of anti-inflammatory agent Naproxen .

HY-14658S

Thalidomide-d4
Thalidomide-d₄ is a deuterium labeled Thalidomide. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties .

HY-105028S

Tenidap-d3
Tenidap-d₃ is the deuterium labeled Tenidap. Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC₅₀ values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties . Tenidap is also a specific SLC26A3 inhibitor .

HY-N0006S1

Demethoxycurcumin-d4
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties .

HY-Y0189S

Methyl Salicylate-d4

Methyl Salicylate-d₄ is the deuterium labeled Methyl Salicylate . Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products . A systemic acquired resistance (SAR) signal in tobacco . A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor .

HY-17589AS

Chloroquine-d5 1 Publications Verification
Chloroquine-d₅ is deuterium labeled Chloroquine (HY-17589A). Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

HY-W768057

Acetamide-13C2,15N

Acetamide- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled Acetamide (HY-Y0946). Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .

HY-B0673S

Pirfenidone-d5
Pirfenidone-d₅ is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .

HY-W740773

Betamethasone-d10 Dipropionate
Betamethasone-d₁₀ Dipropionate is the deuterium labeled Betamethasone dipropionate (HY-13571). Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.

HY-106579S

Tiaprofenic acid-d3
Tiaprofenic acid-d₃ is a deuterium labeled Tiaprofenic acid. Tiaprofenic acid is a nonsteroidal anti-inflammatory agent (NSAID) mainly used in the treatment of rheumatic diseases .

HY-100977S

Dimethoxycurcumin-d6
Dimethoxycurcumin-d₆ is the deuterium labeled Dimethoxycurcumin (HY-100977). Dimethoxycurcumin is a derivative of Curcumin that has anti-inflammatory and antioxidant activities .

HY-B0174AS1

Olsalazine-d3

Olsalazine-d₃ is deuterated labeled Olsalazine (HY-B0174A). Olsalazine is a potent inhibitor of macrophages chemotaxis to LTB4 with an IC₅₀ value of 0.39 mM, also reduces the synthesis of 5-hydroxyeicosatetraenoic acid (5-HETE), 11-HETE, 12-HETE, and 15-HETE in polymorphonuclear leukocyte (PMNL) and mononuclear cells (MNL). Olsalazine can be used for researching ulcerative colitis. Anti-inflammatory activity .

HY-10582S3

Flurbiprofen-d4

Flurbiprofen-d₄ is deuterated labeled Flurbiprofen (HY-10582). Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer .

HY-W052144S

(±) Anabasine-d4 dihydrochloride
(±) Anabasine-d₄ dihydrochloride is deuterium labeled (±) Anabasine dihydrochloride. (±) Anabasine dihydrochloride is the racemate of Anabasine dihydrochloride. Anabasine dihydrochloride is an agonist of α7nAChR and exhibits anti-inflammatory and insecticidal activities .

HY-B0485S

Fluocinonide-d6
Fluocinonide-d₆ is deuterated labeled Fluocinonide (HY-B0485). Fluocinonide (Vanos) is a glucocorticoid steroid with anti-inflammatory activity that acts on skin diseases.

HY-121046S

Flunixin-d3
Flunixin-d₃ is the deuterium labeled Flunixin. Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity .

HY-N1981S1

Triolein-d5
Triolein-d₅ is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties .

HY-17509S

Deracoxib-d3
Deracoxib-d₃ is the deuterium labeled Deracoxib. Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).

HY-N0370S

Bergapten-d3
Bergapten-d₃ is deuterium labeled Bergapten. Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms.

HY-B0625S

Ciclesonide-d7
Ciclesonide-d₇ is the deuterium labeled Ciclesonide. Ciclesonide (RPR251526) is a glucocorticoid with an potent anti-inflammatory activity. Ciclesonide can be used for asthma research .

HY-32343S

Secalciferol-d6
Secalciferol-d₆ is the deuterium labeled Secalciferol. Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification .

HY-B0619S1

Zaltoprofen-13C,d3
Zaltoprofen- ¹³C,d₃ is the ¹³C- and deuterium labeled Zaltoprofen. Zaltoprofen (CN100), a non-steroidal anti-inflammatory drug (NSAID), is a preferential and orally active COX-2 inhibitor, with IC₅₀s of 1.3 and 0.34 μM for COX-1 and COX-2, respectively. Zaltoprofen exhibits powerful anti-inflammatory effects as well as an analgesic action on inflammatory pain .

HY-B1028S

Pantethine-15N2

Pantethine- ¹⁵N₂ is the ¹⁵N₂ labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration .

HY-B1322AS1

Amodiaquine-d10 hydrochloride
Amodiaquine-d₁₀ hydrochloride is deuterated labeled Amodiaquine (HY-B1322A). Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC₅₀ of ~20 μM. Anti-inflammatory effect .

HY-B0174AS2

Olsalazine-d3,15N

Olsalazine-d₃, ¹⁵N is ¹⁵N and deuterated labeled Olsalazine (HY-B0174A). Olsalazine is a potent inhibitor of macrophages chemotaxis to LTB4 with an IC₅₀ value of 0.39 mM, also reduces the synthesis of 5-hydroxyeicosatetraenoic acid (5-HETE), 11-HETE, 12-HETE, and 15-HETE in polymorphonuclear leukocyte (PMNL) and mononuclear cells (MNL). Olsalazine can be used for researching ulcerative colitis. Anti-inflammatory activity .

HY-N0105S2

Rhein-13C4
Rhein- ¹³C₄ (Rheic Acid- ¹³C₄) is ¹³C labeled Rhein. Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects .

HY-B1214S

Prednisolone acetate-d8
Prednisolone acetate-d₈ is the deuterium labeled Prednisolone acetate. Prednisolone acetate (Prednisolone 21-acetate) is an adrenal cortico hormones, with anti-inflammatory, anti-allergic and immune suppressive effects.

HY-B0367S

Lornoxicam-d4
Lornoxicam-d₄ is the deuterium labeled Lornoxicam. Lornoxicam (Chlortenoxicam), a COX-1 and COX-2 inhibitor, is a new nonsteroidal anti-inflammatory agent (NSAID).

HY-137222S

4',5-Dihydroxy Diclofenac-13C6
4',5-Dihydroxy Diclofenac-13C₆ is a deuterated derivative of Diclofenac (HY-15036). Diclofenac is a potent COX inhibitor with anti-inflammatory activity .

HY-13693S

Mometasone furoate-d3
Mometasone furoate-d₃ is a deuterium labeled Mometasone furoate. Mometasone furoate (Sch32088) is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic activity .

HY-B1832S

Prednisone acetate-d3
Prednisone acetate-d₃ is the deuterium labeled Prednisone acetate. Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties .

HY-W654397

Deflazacort-d3
Deflazacort-d3 is a isotope of Deflazacort. Deflazacort is an inactive proagent and is converted rapidly to the active metabolite 21-desacetyldeflazacort. Deflazacort is used as an anti-inflammatory and immunosuppressant .

HY-Y1362S

Ethyl pyruvate-d3
Ethyl pyruvate-d₃ is the deuterium labeled Ethyl pyruvate . Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks