2. Immunology/Inflammation Membrane Transporter/Ion Channel Neuronal Signaling GPCR/G Protein Metabolic Enzyme/Protease
  3. Opioid Receptor GABA Receptor Lipoxygenase COX
  4. 6-Hydroxyflavanone

6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes.

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6-Hydroxyflavanone

6-Hydroxyflavanone Chemical Structure

CAS No. : 4250-77-5

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250 mg In-stock
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6-Hydroxyflavanone Related Antibodies

Top Publications Citing Use of Products

View All Opioid Receptor Isoform Specific Products:

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μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

View All Lipoxygenase Isoform Specific Products:

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5-LOX 12-LOX 15-LOX

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COX COX-1 COX-2 COX-3

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Description

6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes[1][2].

Molecular Weight

240.25

Formula

C15H12O3
CAS No.
Appearance

Solid

SMILES

O=C(C1)C(C=C(O)C=C2)=C2OC1C3=CC=CC=C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (416.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1623 mL 20.8117 mL 41.6233 mL
5 mM 0.8325 mL 4.1623 mL 8.3247 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1623 mL 20.8117 mL 41.6233 mL 104.0583 mL
5 mM 0.8325 mL 4.1623 mL 8.3247 mL 20.8117 mL
10 mM 0.4162 mL 2.0812 mL 4.1623 mL 10.4058 mL
15 mM 0.2775 mL 1.3874 mL 2.7749 mL 6.9372 mL
20 mM 0.2081 mL 1.0406 mL 2.0812 mL 5.2029 mL
25 mM 0.1665 mL 0.8325 mL 1.6649 mL 4.1623 mL
30 mM 0.1387 mL 0.6937 mL 1.3874 mL 3.4686 mL
40 mM 0.1041 mL 0.5203 mL 1.0406 mL 2.6015 mL
50 mM 0.0832 mL 0.4162 mL 0.8325 mL 2.0812 mL
60 mM 0.0694 mL 0.3469 mL 0.6937 mL 1.7343 mL
80 mM 0.0520 mL 0.2601 mL 0.5203 mL 1.3007 mL
100 mM 0.0416 mL 0.2081 mL 0.4162 mL 1.0406 mL
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6-Hydroxyflavanone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Hydroxyflavanone4250-77-5Opioid ReceptorGABA ReceptorLipoxygenaseCOXGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorLOXCyclooxygenaseMuntingia calaburaCOX-25-LOXGABA-Aanti-inflammatoryanti-neuropathicopioidInhibitorinhibitorinhibit

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