2. Others MAPK/ERK Pathway NF-κB Metabolic Enzyme/Protease
  3. NF-κB p38 MAPK Endogenous Metabolite Isotope-Labeled Compounds
  4. Fumaric acid-13C2

Fumaric acid-13C2 is the 13C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension.

For research use only. We do not sell to patients.

Fumaric acid-<sup>13</sup>C<sub>2</sub> Chemical Structure

Fumaric acid-13C2 Chemical Structure

CAS No. : 96503-56-9

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Other Forms of Fumaric acid-13C2:

Fumaric acid-13C2 Related Antibodies

Top Publications Citing Use of Products

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

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Description

Fumaric acid-13C2 is the 13C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fumaric acid-13C2 Related Antibodies
Molecular Weight

118.06

Formula

C213C2H4O4
CAS No.
Unlabeled CAS
SMILES

O=[13C](O)/C=C/[13C](O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Fumaric acid-13C2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fumaric acid-13C296503-56-9NF-κBp38 MAPKEndogenous MetaboliteIsotope-Labeled CompoundsNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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