2. Neuronal Signaling Stem Cell/Wnt Apoptosis
  3. γ-secretase Apoptosis
  4. Itanapraced (Standard)

Itanapraced (Standard) is the analytical standard of Itanapraced. This product is intended for research and analytical applications. Itanapraced (CHF5074) is an orally active γ-secretase modulator and a non-steroidal anti-inflammatory derivative. Itanapraced reduces Aβ42 and Aβ40 secretion with IC50 values of 3.6 and 18.4 μM, respectively. Itanapraced inhibits cell apoptosis of hippocampal neurons induced by oxygen and glucose deprivation (OGD). Itanapraced can be used for the research of Alzheimer's disease.

For research use only. We do not sell to patients.

Itanapraced (Standard) Chemical Structure

Itanapraced (Standard) Chemical Structure

CAS No. : 749269-83-8

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Description
Molecular Weight

325.16

Formula

C16H11Cl2FO2
CAS No.
SMILES

OC(C1(CC1)C(C=C2)=CC(F)=C2C3=CC=C(Cl)C(Cl)=C3)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Itanapraced (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Itanapraced (Standard)749269-83-8γ-secretaseApoptosisGamma secretaseAβ42Aβ40Alzheimer's diseaseH4sweNotch processingapoptosisxcitatory synaptic transmissionInhibitorinhibitorinhibit

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