Resolvin D2 methyl ester

Cat. No.: HY-W708469: Data Sheet Handling Instructions
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Resolvin D2 methyl ester is an ester derivative of the DHA (HY-B2167) metabolite Resolvin D2 (HY-121636) with anti-inflammatory and anti-infective activities. Resolvin D2 is a leukocyte modulator and a potent inhibitor of neuronal TRPV1 (IC₅₀=0.1 nM) and TRPA1 (IC₅₀=2 nM). Resolvin D2 can be used in sepsis research.

For research use only. We do not sell to patients.

Resolvin D2 methyl ester Chemical Structure

CAS No. : 810668-53-2

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TRPC TRPM TRPV TRPA TRPML

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Description	Resolvin D2 methyl ester is an ester derivative of the DHA (HY-B2167) metabolite Resolvin D2 (HY-121636) with anti-inflammatory and anti-infective activities. Resolvin D2 is a leukocyte modulator and a potent inhibitor of neuronal TRPV1 (IC₅₀=0.1 nM) and TRPA1 (IC₅₀=2 nM). Resolvin D2 can be used in sepsis research^[1]^[2]^[3].
Molecular Weight	390.51
Formula	C₂₃H₃₄O₅
CAS No.	810668-53-2
SMILES	CC/C=C\C[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)C/C=C\CCC(OC)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (262 KB) Handling Instructions (2659 KB)
References	[1]. Siddiqui YD, et al. Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis. Front Immunol. 2019 Feb 26;10:307. [Content Brief] [Content Brief] [2]. Spite M, et al. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature. 2009 Oct 29;461(7268):1287-91. [Content Brief] [Content Brief] [3]. Park CK, et al. Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1.6. J Neurosci. 2011 Dec 14;31(50):18433-8. [Content Brief]