2. Others Antibody-drug Conjugate/ADC Related Vitamin D Related/Nuclear Receptor Immunology/Inflammation
  3. Glucocorticoid Receptor ADC Cytotoxin Isotope-Labeled Compounds
  4. Budesonide-d6

Budesonide-d6 is deuterium labeled Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma.

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Budesonide-d<sub>6</sub> Chemical Structure

Budesonide-d6 Chemical Structure

CAS No. : 1134189-63-1

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Other Forms of Budesonide-d6:

Budesonide-d6 Related Antibodies

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Description

Budesonide-d6 is deuterium labeled Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma[1][2][3][4].

Molecular Weight

436.57

Formula

C25H28D6O6
CAS No.
Unlabeled CAS
SMILES

O=C1C([2H])=C[C@]2(C(C([2H])(C[C@@]3([C@@]2([C@@H](C[C@]4([C@@]3(C[C@H]5OC(O[C@]54C(C([2H])(O)[2H])=O)CCC)[H])C)O)[H])[H])[2H])=C1[2H])C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 215 mg/mL (492.48 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2906 mL 11.4529 mL 22.9058 mL
5 mM 0.4581 mL 2.2906 mL 4.5812 mL
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2906 mL 11.4529 mL 22.9058 mL 57.2646 mL
5 mM 0.4581 mL 2.2906 mL 4.5812 mL 11.4529 mL
10 mM 0.2291 mL 1.1453 mL 2.2906 mL 5.7265 mL
15 mM 0.1527 mL 0.7635 mL 1.5271 mL 3.8176 mL
20 mM 0.1145 mL 0.5726 mL 1.1453 mL 2.8632 mL
25 mM 0.0916 mL 0.4581 mL 0.9162 mL 2.2906 mL
30 mM 0.0764 mL 0.3818 mL 0.7635 mL 1.9088 mL
40 mM 0.0573 mL 0.2863 mL 0.5726 mL 1.4316 mL
50 mM 0.0458 mL 0.2291 mL 0.4581 mL 1.1453 mL
60 mM 0.0382 mL 0.1909 mL 0.3818 mL 0.9544 mL
80 mM 0.0286 mL 0.1432 mL 0.2863 mL 0.7158 mL
100 mM 0.0229 mL 0.1145 mL 0.2291 mL 0.5726 mL
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Budesonide-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Budesonide-d61134189-63-1Glucocorticoid ReceptorADC CytotoxinIsotope-Labeled CompoundsADC PayloadInhibitorinhibitorinhibit

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