2. Others Immunology/Inflammation
  3. Reference Standards IRAK
  4. AS2444697 (Standard)

AS2444697 (Standard) is the analytical standard of AS2444697 (HY-18992). This product is intended for research and analytical applications. AS2444697 is an orally active IRAK-4 inhibitor with an IC50 of 21 nM. AS2444697 potently inhibits human and rat IRAK-4 activity. AS2444697 exhibits renoprotective effects through anti-inflammatory action.

For research use only. We do not sell to patients.

AS2444697 (Standard)

AS2444697 (Standard) Chemical Structure

CAS No. : 1287665-60-4

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Information

AS2444697 (Standard) is the analytical standard of AS2444697 (HY-18992). This product is intended for research and analytical applications. AS2444697 is an orally active IRAK-4 inhibitor with an IC50 of 21 nM. AS2444697 potently inhibits human and rat IRAK-4 activity. AS2444697 exhibits renoprotective effects through anti-inflammatory action.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

432.86

Formula

C19H21ClN6O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=NN(C2CCOCC2)C=C1NC(C3=COC(C4=CC(C)=NC=C4)=N3)=O)N.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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AS2444697 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AS2444697 (Standard)1287665-60-4Reference StandardsIRAKInterleukin-1 receptor associated kinaseIL-1R associated kinaseInhibitorinhibitorinhibit

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AS2444697 (Standard)
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HY-18992R
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