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  5. 6,7-Diketolithocholic acid

6,7-Diketolithocholic acid  (Synonyms: 6,7-DiketoLCA)

Cat. No.: HY-N11257 Purity: 99.78%
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6,7-Diketolithocholic acid (6,7-DiketoLCA) is an important bioactive compound with anti-inflammatory and bile acid metabolism regulating activities. 6,7-Diketolithocholic acid can affect lipid metabolism and regulate the balance of glucose and lipid metabolism in the body. 6,7-Diketolithocholic acid has also been studied for the inhibition of diseases related to abnormal cholesterol metabolism.

For research use only. We do not sell to patients.

6,7-Diketolithocholic acid Chemical Structure

6,7-Diketolithocholic acid Chemical Structure

CAS No. : 1643669-23-1

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6,7-Diketolithocholic acid Related Antibodies

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Description

6,7-Diketolithocholic acid (6,7-DiketoLCA) is an important bioactive compound with anti-inflammatory and bile acid metabolism regulating activities. 6,7-Diketolithocholic acid can affect lipid metabolism and regulate the balance of glucose and lipid metabolism in the body. 6,7-Diketolithocholic acid has also been studied for the inhibition of diseases related to abnormal cholesterol metabolism.

Molecular Weight

404.54

Synonyms

6,7-DiketoLCA

Formula

C24H36O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@](C(C([C@]1([H])C[C@@H](CC2)O)=O)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C
Structure Classification
Initial Source

mouse blood
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (247.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4719 mL 12.3597 mL 24.7194 mL
5 mM 0.4944 mL 2.4719 mL 4.9439 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4719 mL 12.3597 mL 24.7194 mL 61.7986 mL
5 mM 0.4944 mL 2.4719 mL 4.9439 mL 12.3597 mL
10 mM 0.2472 mL 1.2360 mL 2.4719 mL 6.1799 mL
15 mM 0.1648 mL 0.8240 mL 1.6480 mL 4.1199 mL
20 mM 0.1236 mL 0.6180 mL 1.2360 mL 3.0899 mL
25 mM 0.0989 mL 0.4944 mL 0.9888 mL 2.4719 mL
30 mM 0.0824 mL 0.4120 mL 0.8240 mL 2.0600 mL
40 mM 0.0618 mL 0.3090 mL 0.6180 mL 1.5450 mL
50 mM 0.0494 mL 0.2472 mL 0.4944 mL 1.2360 mL
60 mM 0.0412 mL 0.2060 mL 0.4120 mL 1.0300 mL
80 mM 0.0309 mL 0.1545 mL 0.3090 mL 0.7725 mL
100 mM 0.0247 mL 0.1236 mL 0.2472 mL 0.6180 mL
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6,7-Diketolithocholic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6,7-Diketolithocholic acid1643669-23-16,7-DiketoLCAOthersInhibitorinhibitorinhibit

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