2. MAPK/ERK Pathway Stem Cell/Wnt Immunology/Inflammation
  3. ERK JNK NO Synthase COX
  4. Ambuic acid

Ambuic acid  (Synonyms: (+)-Ambuic acid)

Cat. No.: HY-126858 Purity: 98.00%
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Handling Instructions Technical Support

Ambuic acid exhibits antimicrobial activity against Staphylococcus aureus, with IC50 of 43.9 μM for strain ATCC 6538. Ambuic acid is an inhbitor for the biosynthesis of cyclic peptide quorum sensing molecules (quormones) in gram-positive bacteria. Ambuic acid exhibits anti-inflammatory activity through ERK/JNK/MAPK signaling pathway.

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Ambuic acid Chemical Structure

Ambuic acid Chemical Structure

CAS No. : 340774-69-8

Size Price Stock Quantity
500 μg In-stock

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Based on 1 publication(s) in Google Scholar

Ambuic acid Related Antibodies

Top Publications Citing Use of Products

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ERK ERK1 ERK2 ERK5 ERK8

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JNK1 JNK2 JNK3 JNK

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nNOS iNOS eNOS

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COX COX-1 COX-2 COX-3

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Description

Ambuic acid exhibits antimicrobial activity against Staphylococcus aureus, with IC50 of 43.9 μM for strain ATCC 6538. Ambuic acid is an inhbitor for the biosynthesis of cyclic peptide quorum sensing molecules (quormones) in gram-positive bacteria. Ambuic acid exhibits anti-inflammatory activity through ERK/JNK/MAPK signaling pathway[1][2][3].

Molecular Weight

350.41

Formula

C19H26O6
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(O)/C(C)=C/C[C@]12C(C(/C=C/CCCCC)=C(CO)[C@@H](O)[C@@]1([H])O2)=O
Structure Classification
Initial Source

Pestalotiopsis
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 98.0%

SDS (251 KB)

COA (247 KB)

Handling Instructions (2659 KB)
References
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Ambuic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ambuic acid340774-69-8(+)-Ambuic acidERKJNKNO SynthaseCOXExtracellular signal regulated kinasesc-Jun N-terminal kinaseNitric oxide synthasesNOSCyclooxygenaseRAW264.7Staphylococcus aureusATCC 6538Inhibitorinhibitorinhibit

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