2. Metabolic Enzyme/Protease NF-κB
  3. Endogenous Metabolite Keap1-Nrf2 NF-κB
  4. Pyrraline

Pyrraline is an Nrf2 pathway activator with antioxidant and anti-inflammatory effects. Pyrraline upregulates antioxidant enzymes such as NAD(P)H dehydrogenase (NQO1) and heme oxygenase-1 (HO-1) via antioxidant response element (ARE) activation, while inhibiting NFκB-mediated inflammation. Pyrraline is promising for research of metabolic disorders (such as diabetic nephropathy) and cancers.

For research use only. We do not sell to patients.

Pyrraline

Pyrraline Chemical Structure

CAS No. : 74509-14-1

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Pyrraline Related Antibodies

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Description

Pyrraline is an Nrf2 pathway activator with antioxidant and anti-inflammatory effects. Pyrraline upregulates antioxidant enzymes such as NAD(P)H dehydrogenase (NQO1) and heme oxygenase-1 (HO-1) via antioxidant response element (ARE) activation, while inhibiting NFκB-mediated inflammation. Pyrraline is promising for research of metabolic disorders (such as diabetic nephropathy) and cancers[1][2].

Molecular Weight

254.28

Formula

C12H18N2O4
CAS No.
SMILES

C1=C(N(C(=C1)C=O)CCCC[C@@H](C(=O)O)N)CO
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Pyrraline Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyrraline74509-14-1Endogenous MetaboliteKeap1-Nrf2NF-κBNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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