2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. Curcumenol (Standard)

Curcumenol (Standard)  (Synonyms: (+)-Curcumenol (Standard))

Cat. No.: HY-N2259R
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Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells.

For research use only. We do not sell to patients.

Curcumenol (Standard)

Curcumenol (Standard) Chemical Structure

CAS No. : 19431-84-6

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Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells.

SMILES

C[C@@H]1[C@@](O[C@@]2(O)/C3=C(C)\C)(C3)[C@@](C(C)=C2)([H])CC1
Structure Classification
Initial Source
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Curcumenol (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Curcumenol (Standard)19431-84-6(+)-Curcumenol (Standard)Cytochrome P450CYPsInhibitorinhibitorinhibit

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