2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Thiotaurine

Thiotaurine is the metabolite of Cystine. Thiotaurine is a sulfur donor, which may probably modulates the activity of GAPDH, followed by the pparticipation in neutrophil activation and leukocytes energy metabolism. Thiotaurine is a potential anti-inflammatory agent and immunomodulator.

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Thiotaurine Chemical Structure

Thiotaurine Chemical Structure

CAS No. : 2937-54-4

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Thiotaurine Related Antibodies

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Description

Thiotaurine is the metabolite of Cystine. Thiotaurine is a sulfur donor, which may probably modulates the activity of GAPDH, followed by the pparticipation in neutrophil activation and leukocytes energy metabolism. Thiotaurine is a potential anti-inflammatory agent and immunomodulator[1].

Molecular Weight

141.21

Formula

C2H7NO2S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(S)(CCN)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (708.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.0817 mL 35.4083 mL 70.8165 mL
5 mM 1.4163 mL 7.0817 mL 14.1633 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.27%

COA (246 KB) HNMR (246 KB) RP-HPLC (206 KB) MS (68 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.0817 mL 35.4083 mL 70.8165 mL 177.0413 mL
5 mM 1.4163 mL 7.0817 mL 14.1633 mL 35.4083 mL
10 mM 0.7082 mL 3.5408 mL 7.0817 mL 17.7041 mL
15 mM 0.4721 mL 2.3606 mL 4.7211 mL 11.8028 mL
20 mM 0.3541 mL 1.7704 mL 3.5408 mL 8.8521 mL
25 mM 0.2833 mL 1.4163 mL 2.8327 mL 7.0817 mL
30 mM 0.2361 mL 1.1803 mL 2.3606 mL 5.9014 mL
40 mM 0.1770 mL 0.8852 mL 1.7704 mL 4.4260 mL
50 mM 0.1416 mL 0.7082 mL 1.4163 mL 3.5408 mL
60 mM 0.1180 mL 0.5901 mL 1.1803 mL 2.9507 mL
80 mM 0.0885 mL 0.4426 mL 0.8852 mL 2.2130 mL
100 mM 0.0708 mL 0.3541 mL 0.7082 mL 1.7704 mL
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Thiotaurine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thiotaurine2937-54-4Endogenous MetaboliteInhibitorinhibitorinhibit

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