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Results for "

<sup>18</sup>F

" in MedChemExpress (MCE) Product Catalog:

3241

Inhibitors & Agonists

5

Screening Libraries

34

Fluorescent Dye

52

Biochemical Assay Reagents

89

Peptides

8

MCE Kits

80

Inhibitory Antibodies

334

Natural
Products

340

Recombinant Proteins

1311

Isotope-Labeled Compounds

158

Antibodies

17

Click Chemistry

312

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0389S29
    D-Glucose-18O

    Glucose-<sup>18sup>O; D-(+)-Glucose-<sup>18sup>O; Dextrose-<sup>18sup>O

    		 Endogenous Metabolite Metabolic Disease Cancer
    D-Glucose- 18O is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules
    D-Glucose-18O
  • HY-P99712
    Lonigutamab

    hz208F2-4

    		 IGF-1R Apoptosis ADC Antibody Cancer
    Lonigutamab (hz208F2-4) is a humanized anti-IGF-1R monoclonal antibody, serveing as a targeting vector for antibody-drug conjugates (ADCs). Lonigutamab causes G2-M phase cell cycle arrest and increases apoptosis in IGF-1R-overexpressing tumor cells. Lonigutamab demonstrates potent antitumor efficacy in IGF-1R-overexpressing xenograft models. Lonigutamab can be used for the study of Solid tumors with overexpression of IGF-1R and thyroid eye diseases [1]sup>[2].
    Lonigutamab
  • HY-N12604
    Penicisteck acid F

    		NF-κB Others
    Penicisteck acid F (Compound 2) is a Marine derived tanzanic acid derivative that is a NF-κB inhibitor. Penicisteck acid F inhibits osteoclast expression by decreasing RANKL-induced IκBα degradation, NF-κB p65 nuclear translocation, NFATc1 activation and nuclear translocation, and related mRNA expression. Penicisteck acid F can be used in osteoporosis research .
    Penicisteck acid F
  • HY-N1208
    Spiradine F

    O-Acetylspiradine G; Spiradine G acetate

    		 Others Cardiovascular Disease
    Spiradine F is a main alkaloidal component of spiraea japonioa L. fil. Spiradine F derivative can inhibit platelet-activating factor (PAF)-induced platelet aggregation .
    Spiradine F
  • HY-B0389S31
    D-Glucose-18O-2

    Glucose-<sup>18sup>O-2; D-(+)-Glucose-<sup>18sup>O-2; Dextrose-<sup>18sup>O-2

    		 Endogenous Metabolite Metabolic Disease Cancer
    D-Glucose- 18O-2 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
    D-Glucose-18O-2
  • HY-N0537S
    Xylose-18O

    D-(+)-Xylose-18O-<sup>18sup>O; (+)-Xylose-18O-<sup>18sup>O; Wood sugar-<sup>18sup>O

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Xylose- 18O is the 18O labeled Xylose.
    Xylose-18O
  • HY-B0389S30
    D-Glucose-18O-1

    Glucose-<sup>18sup>O-1; D-(+)-Glucose-<sup>18sup>O-1; Dextrose-<sup>18sup>O-1

    		 Endogenous Metabolite Metabolic Disease Cancer
    D-Glucose- 18O-1 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
    D-Glucose-18O-1
  • HY-B0389S32
    D-Glucose-18O-3

    Glucose-<sup>18sup>O-3; D-(+)-Glucose-<sup>18sup>O-3; Dextrose-<sup>18sup>O-3

    		 Endogenous Metabolite Metabolic Disease Cancer
    D-Glucose- 18O-3 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
    D-Glucose-18O-3
  • HY-B0400S15
    D-Sorbitol-18O-1

    Sorbitol-<sup>18sup>O-1; D-Glucitol-<sup>18sup>O-1

    		 Endogenous Metabolite Others
    D-Sorbitol- 18O-1 is the 18O labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
    D-Sorbitol-18O-1
  • HY-N16392
    14-epi-Berkeleylactone F

    		Endogenous Metabolite Infection
    14-epi-Berkeleylactone F (Compound 8) is a C-14 epimer of Berkeleylactone F (HY-N8386). 14-epi-Berkeleylactone F can be isolated from Penicillium turbatum NRRL 5630. 14-epi-Berkeleylactone F has no significant biological activity against bacterium (Staphylococcus aureus, Bacillus subtilis and E. coli), fungi Candida albicans, the parasite Giardia duodenalis and NS-1 murine myeloma cells .
    14-epi-Berkeleylactone F
  • HY-W014901S1
    Bisphenol F-13C12

    BPF-<sup>13sup>C12; 4,4'-Dihydroxydiphenylmethane-<sup>13sup>C12

    		 Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Akt GSK-3 Apoptosis Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology
    Bisphenol F- 13C12 is the 13C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260) .
    Bisphenol F-13C12
  • HY-W014901S
    Bisphenol F-13C6

    BPF-<sup>13sup>C6; 4,4'-Dihydroxydiphenylmethane-<sup>13sup>C6

    		 Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Akt GSK-3 Apoptosis Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology
    Bisphenol F- 13C6 is the 13C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260) .
    Bisphenol F-13C6
  • HY-113246
    15-keto-Prostaglandin F2a

    15-keto-PGF2α

    		 Prostaglandin Receptor Endogenous Metabolite Endocrinology
    15-keto-Prostaglandin F2α (15-keto-PGF2α) is a metabolite of Prostaglandin F2α. Prostaglandin F2α. Prostaglandin F2α is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist and plays a key role in the onset and progression of labour .
    15-keto-Prostaglandin F2a
  • HY-103447S1
    Zearalenone-13C18

    Mycotoxin F2-<sup>13sup>C18; Toxin F2-<sup>13sup>C18

    		 Isotope-Labeled Compounds Others
    Zearalenone- 13C18 (Mycotoxin F2- 13C18; Toxin F2- 13C18) is the 13C labeled Zearalenone (HY-103447) . Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .
    Zearalenone-13C18
  • HY-119649S
    Flonicamid-15N,18O

    IKI220-<sup>15sup>N<sup>18sup>O

    		 Isotope-Labeled Compounds Parasite Infection
    Flonicamid- 15N,18O (IKI220- 15N,18O) is 15N labeled Flonicamid. Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .
    Flonicamid-15N,18O
  • HY-N7092S20
    D(-​)​-​Fructose-18O-1

    D-Fructose-<sup>18sup>O-1

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    D(-​)​-​Fructose- 18O-1 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants .
    D(-​)​-​Fructose-18O-1
  • HY-N7092S21
    D-Fructose-18O-2

    D(-​)​-​Fructose-<sup>18sup>O-2

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    D-Fructose- 18O-2 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants .
    D-Fructose-18O-2
  • HY-12956S2
    Dinoprost-13C5

    Prostaglandin F2α-<sup>13sup>C5; PGF2α-<sup>13sup>C5

    		 Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis Isotope-Labeled Compounds Endocrinology
    Dinoprost- 13C5 is 13C labeled Dinoprost (HY-12956). Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour .
    Dinoprost-13C5
  • HY-103447S2
    Zearalenone-13C7

    Mycotoxin F2-<sup>13sup>C7; Toxin F2-<sup>13sup>C7

    		 Isotope-Labeled Compounds Estrogen Receptor/ERR Others
    Zearalenone- 13C7 (Mycotoxin F2- 13C7) is 13C labeled Zearalenone. Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .
    Zearalenone-13C7
  • HY-146232
    F 13714

    F 14679

    		 5-HT Receptor Others
    F 13714 (F 14679) is a prototypical 5-HT1A agonist with a pKi of 10.23. F 13714 induces large Ca 2+ responses .
    F 13714
  • HY-P990221
    Anti-Mouse IL-17F Antibody (MM17F8F5.1A9)

    		Interleukin Related Infection Neurological Disease Cancer
    Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse IL-17F. Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) can neutralize IL-17. Anti-Mouse IL-17F Antibody (MM17F8F5.1A9) can be used for the researches of cancer, infection and neurological disease, such as Alzheimer’s disease (AD) and pancreatic cancer .
    Anti-Mouse IL-17F Antibody (MM17F8F5.1A9)
  • HY-N15473
    Isopaucifloral F

    (±)-Isopaucifloral F

    		 Estrogen Receptor/ERR Drug Derivative Inflammation/Immunology
    Isopaucifloral F ((±)-Isopaucifloral F) is a Resveratrol (HY-16561)-derived sesquiterpenes. Isopaucifloral F is an orally active ERβ agonist (EC50: 46.96 μM). Isopaucifloral F has antiosteoporosis activity. LD50 in rats: > 5 mg/kg .
    Isopaucifloral F
  • HY-115969
    F-17

    		Bacterial Infection
    F-17 is a potential inhibitor of virulence factor. F-17 shows very significant inhibitory effect on biofilm, elastase, pyocyanin, and swarming motility. F-17 also shows a good binding effect on LasR and PqsR. F-17 has no obvious cytotoxicity .
    F-17
  • HY-P2098
    Alamethicin F 50

    		Antibiotic Bacterial Fungal Infection
    Alamethicin F 50 is an antibiotic. Alamethicin F 50 is composed of membrane-active peptide, containing 75% Alamethicin F 50/5 and 10% Alamethicin F 50/7. Alamethicin F 50 is exhibits antifungal and antibacterial activity by disrupting the integrity of microbial cell membranes, resulting in leakage of cell contents and death of the microorganisms. Alamethicin F 50 is able to reduce the surface tension of water, which can be used as a surfactant or detergent .
    Alamethicin F 50
  • HY-W128969S
    5-Bromo-2,4-di-tert-butoxypyrimidine-13C,15N2

    IFLAB-BB F1371-0151-<sup>13sup>C,<sup>15sup>N2; 5-Bromo-2,4-bis(1,1-dimethylethoxy)pyrimidine-<sup>13sup>C,<sup>15sup>N2

    		 Isotope-Labeled Compounds Others
    5-Bromo-2,4-di-tert-butoxypyrimidine- 13C, 15N2 (IFLAB-BB F1371-0151- 13C, 15N2) is the 13C- and 15N-labeled 5-Bromo-2,4-di-tert-butoxypyrimidine (HY-W128969).
    5-Bromo-2,4-di-tert-butoxypyrimidine-13C,15N2
  • HY-12542S
    Dantrolene-13C3

    F 368-<sup>13sup>C3

    		 Isotope-Labeled Compounds Glutathione Reductase (GR) Neurological Disease Inflammation/Immunology
    Dantrolene- 13C3 is the 13C3 labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.
    Dantrolene-13C3
  • HY-N0384S3
    Homovanillic acid-13C6,18O

    Vanilacetic acid-<sup>13sup>C6,<sup>18sup>O

    		 Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite Neurological Disease Metabolic Disease
    Homovanillic acid- 13C6, 18O (Vanilacetic acid- 13C6, 18O) is the 13C- and 18O-labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
    Homovanillic acid-13C6,18O
  • HY-106902
    F-1394

    		Acyltransferase Cardiovascular Disease
    F-1394 is an orally active acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor that inhibits dietary cholesterol absorption in mice. F-1394 can be used in cardiovascular disease research .
    F-1394
  • HY-125349
    A-83016F

    		Antibiotic Infection
    A-83016F is an antibiotic. A-83016F has weak antimicrobial activity. A-83016F can be isolated from the culture broth of an unidentified actinomycete designated A83016 .
    A-83016F
  • HY-113824
    RID-F

    Ridaifen-F

    		 Proteasome Cancer
    RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively .
    RID-F
  • HY-N6217
    F-14329

    		Endogenous Metabolite Others
    F-14329 is a tetramic acid fungal metabolite .
    F-14329
  • HY-N7223
    Lappaol F

    		YAP Apoptosis Cancer
    Lappaol F, a lignin, is an anticancer agent. Lappaol F inhibits YAP mRNA and protein level. Lappaol F inhibits tumor cell growth by inducing cell cycle arrest. Lappaol F induces cancer cell apoptosis, and inhibits tumor growth. Lappaol F can be isolated from Arctium lappa Linne (Asteraceae) .
    Lappaol F
  • HY-176362S
    4-F-Benzenesulfonate-pyrrole(2-F-Ph)-methylamine-d3

    		Isotope-Labeled Compounds Others
    4-F-Benzenesulfonate-pyrrole(2-F-Ph)-methylamine-d3 is the deuterium labeled 4-F-Benzenesulfonate-pyrrole(2-F-Ph)-methylamine.
    4-F-Benzenesulfonate-pyrrole(2-F-Ph)-methylamine-d3
  • HY-D0159
    ZnAF-1F

    		Fluorescent Dye Others
    ZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn 2+ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm .
    ZnAF-1F
  • HY-106031
    F-14512

    		Topoisomerase Cancer
    F-14512 is a targeted cytotoxic compound that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 combines an epipodophyllotoxin core that targets topoisomerase II with a spermine group that acts as a cell delivery vehicle, with improved selectivity for tumor cells. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and demonstrates high potency in multiple human cell lines (median IC50=0.18 μM). In the MX1 breast tumor xenograft model, F-14512 exhibits potent antitumor activity .
    F-14512
  • HY-19886
    F 16915

    		Drug Intermediate Cardiovascular Disease
    F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation .
    F 16915
  • HY-N8619
    Minimolide F

    		Others Cancer
    Minimolide F is a sesquiterpene lactone. Minimolide F has inhibitory activity against human nasopharyngeal cancer cells. Minimolide F can be used for the research of cancer .
    Minimolide F
  • HY-N10952
    Epicornuin F

    		Others Cancer
    Epicornuin F is a prenylated flavonoid. Epicornuin F can be isolated from the leaves of Epimedium brevicornu. Epicornuin F has the cytotoxic activity against HepG2 cells with an IC50 value of 33.4 μM. Epicornuin F can be used for the research of cancer .
    Epicornuin F
  • HY-153839
    ODN 4084-F

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 4084-F is a class B (‘broadly-active’) inhibitory ODN. ODN 4084-F is potent inhibitor of TLR9-induced B cells and macrophages.
    ODN 4084-F
  • HY-153839A
    ODN 4084-F sodium

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 4084-F sodium is a class B (‘broadly-active’) inhibitory ODN. ODN 4084-F sodium is potent inhibitor of TLR9-induced B cells and macrophages.
    ODN 4084-F sodium
  • HY-N10380
    Inonotusol F

    		Others Metabolic Disease
    Inonotusol F is a triterpene isolated from Inonotus obliquus. Inonotusol F shows hepatoprotective effects against D-galactosamine-induced WB-F344 cell damage .
    Inonotusol F
  • HY-15583
    Auristatin F

    		ADC Payload Microtubule/Tubulin Cancer
    Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .
    Auristatin F
  • HY-N10471
    F3226-1387

    		Parasite Endogenous Metabolite Infection
    F3226-1387 is a potent Entamoeba histolytica O-acetylserine sulfhydrylase EhOASS3 inhibitor with an IC50 value of 38 μM. F3226-1387 can suppress the growth of the amoeba .
    F3226-1387
  • HY-161758
    F0045(S)

    		Influenza Virus Infection
    F0045(S) is a potent influenza hemagglutinin inhibitor with a KD value of 6.1 µM. F0045(S) protects human cells from influenza infection .
    F0045(S)
  • HY-172958
    F6524-1593

    		Anaplastic lymphoma kinase (ALK) Cancer
    F6524-1593 is an ALK inhibitor. F6524-1593 has inhibitory activity against A549 and HepG-2 cells with IC50 values of 161.1 μM and 91.03 μM, respectively. F6524-1593 can be used in the research of ALK-related cancers (such as non-small cell lung cancer, lymphoma and neuroblastoma) .
    F6524-1593
  • HY-N11430
    F1839-I

    		HIV Infection
    F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC50 value of 15.6 μM .
    F1839-I
  • HY-138881
    Lenalidomide-6-F

    		Ligands for E3 Ligase Cancer
    Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC .
    Lenalidomide-6-F
  • HY-N14022
    Glidobactin F

    		Antibiotic Fungal Infection Cancer
    Glidobactin F is an anti-tumor antibiotic. Glidobactin F has the activity against pathogenic fungi and yeast. Glidobactin F also extends the survival of mice inoculated with leukemia P388 cells .
    Glidobactin F
  • HY-124421R
    5F-203 (Standard)

    		Aryl Hydrocarbon Receptor Others
    5F-203 (Standard) is the analytical standard of 5F-203. This product is intended for research and analytical applications. 5F-203 (NSC-703786) is a cytotoxic molecule that forms DNA adducts and cell cycle arrest. 5F-203 induces aryl hydrocarbon receptor (AhR) signaling and elevates expression of CYP1A1. 5F-203 also increases the levels of reactive oxygen species as well as activates JNK, ERK, and p38 .
    5F-203 (Standard)
  • HY-162142
    BB2-50F

    		Bacterial Succinate Dehydrogenase Reactive Oxygen Species (ROS) Infection
    BB2-50F, a potent M. tuberculosis inhibitor, is a succinate dehydrogenase and F1Fo-ATP synthase inhibitor. BB2-50F rapidly sterilizes both replicating and non-replicating cultures of M. tuberculosis. BB2-50F inhibits succinate oxidation, decreases the activity of the tricarboxylic acid (TCA) cycle, and results in succinate secretion from M. tuberculosis. BB2-50F induces reactive oxygen species (ROS) in M. tuberculosis .
    BB2-50F

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