2. Immunology/Inflammation
  3. C-type Lectin-like Receptors (CTLRs)
  4. Anti-Mouse/Human KLRG-1 Antibody (2F1)

Anti-Mouse/Human KLRG-1 Antibody (2F1) 

Cat. No.: HY-P990205 Purity: 95.00%
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Anti-Mouse/Human KLRG-1 Antibody (2F1) is a Syrian hamster-derived IgG type antibody inhibitor, targeting to mouse/human KLRG-1. Anti-Mouse/Human KLRG-1 Antibody (2F1) neutralizes KLRG1. Anti-Mouse/Human KLRG-1 Antibody (2F1) reduces T-cell receptor signals and regulatory T-cell accumulation. Anti-Mouse/Human KLRG-1 Antibody (2F1) can be used for the researches of immunology.

For research use only. We do not sell to patients.

Anti-Mouse/Human KLRG-1 Antibody (2F1)

Anti-Mouse/Human KLRG-1 Antibody (2F1) Chemical Structure

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Description

Anti-Mouse/Human KLRG-1 Antibody (2F1) is a Syrian hamster-derived IgG type antibody inhibitor, targeting to mouse/human KLRG-1. Anti-Mouse/Human KLRG-1 Antibody (2F1) neutralizes KLRG1. Anti-Mouse/Human KLRG-1 Antibody (2F1) reduces T-cell receptor signals and regulatory T-cell accumulation. Anti-Mouse/Human KLRG-1 Antibody (2F1) can be used for the researches of immunology[1][2].

Isotype

Syrian hamster IgG
Species Reactivity

Human/Mouse
IC50 & Target

KLRG-1
In Vitro

Anti-Mouse/Human KLRG-1 Antibody (2F1) (5 μg/mL, 8 h or 3 days) reduces T-cell receptor signals and regulatory T-cell accumulation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse/Human KLRG-1 Antibody (2F1) Related Antibodies
In Vivo

Anti-Mouse/Human KLRG-1 Antibody (2F1) (10 mg/kg, i.p., at day 0, 7, 14 and 21) neutralizes KLRG1 in WT or Rag1–/– mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: WT or Rag1–/– mice[2]
Dosage: 10 mg/kg
Administration: Intraperitoneally injection, at day 0, 7, 14 and 21
Result: Neutralized KLRG1.
Gene ID

50928  [NCBI]

Accession
Application

ELISA, FACS, Functional assay, Research in vivo
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Mouse/Human KLRG-1 Antibody (2F1)]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-Mouse/Human KLRG-1 Antibody (2F1) Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse/Human KLRG-1 Antibody (2F1)C-type Lectin-like Receptors (CTLRs)KLRG-1T cellsTregImmunologyInhibitorinhibitorinhibit

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