1. Immunology/Inflammation
  2. FAP
  3. FAP-IN-6

FAP-IN-6 (Compound 21) is a selectivity FAP inhibitor with an IC50 of 13 pM. FAP-IN-6 has a high metabolic stability. FAP-IN-6 labeled with 18F can be used as a positron emission tomography (PET) tracer. FAP-IN-6 can be used for microenvironment of cancers research.

For research use only. We do not sell to patients.

FAP-IN-6

FAP-IN-6 Chemical Structure

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Description

FAP-IN-6 (Compound 21) is a selectivity FAP inhibitor with an IC50 of 13 pM. FAP-IN-6 has a high metabolic stability. FAP-IN-6 labeled with 18F can be used as a positron emission tomography (PET) tracer. FAP-IN-6 can be used for microenvironment of cancers research[1].

Molecular Weight

610.68

Formula

C30H39FN8O5

SMILES

O=C(C1=CC=NC2=CC=C(C=C21)N(CCCN3N=NC(COCCOCCOCCF)=C3)C)NCC(N4CCC[C@H]4C#N)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FAP-IN-6
Cat. No.:
HY-175330
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