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1850

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

111

Biochemical Assay Reagents

224

Peptides

MCE Kits

Inhibitory Antibodies

258

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Products

268

Recombinant Proteins

100

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195

Antibodies

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Oligonucleotides

Targets Recommended: Photosystem II CD74

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-120901

II-B08	SHP2 SHP1	Cancer
II-B08 is a reversible and noncompetitive SHP2 inhibitor (IC₅₀: 5.5 μM, 15.7, 14.3 μM for SHP2, SHP1, PTP1B). II-B08 can be used for cancer research .

HY-P1165

Urotensin II-related peptide	Urotensin Receptor	Cardiovascular Disease
Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor .

HY-W278582

Topoisomerase II inhibitor 14	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibtor. Topoisomerase II inhibitor 14 induces apoptosis and arrests cell cycle at S phase and G2-M phases. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO. Topoisomerase II inhibitor 14 can be used for the study of neck squamous cell carcinoma (HNSCC) .

HY-163174

II399	Amine N-methyltransferase	Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
II399 is a potent, selective NNMT bisubstrate inhibitor containing an unconventional SAM mimic, with a K_i of 5.9 nM. II399 exhibits an explicit pattern of competitive inhibition for NAM. II399 occupies both the substrate and cofactor binding pockets. II399 has the potential for the research of cancers, metabolic, cardiovascular, and neurodegenerative diseases .

HY-149238

Topo II/HDAC-IN-1	Topoisomerase HDAC Apoptosis	Cancer
Topo II/HDAC-IN-1 (7d) exhibits excellent dual inhibitory activities against Topo II and HDAC. Topo II/HDAC-IN-1 (8d) induces apoptosis .

HY-149239

Topo II/HDAC-IN-2	Topoisomerase HDAC Apoptosis	Cancer
Topo II/HDAC-IN-2 (8d) exhibits excellent dual inhibitory activities against Topo II and HDAC. Topo II/HDAC-IN-2 (8d) induces apoptosis .

HY-P1168

[Orn8]-Urotensin II (human)	Urotensin Receptor	Cardiovascular Disease
[Orn8]-Urotensin II (human), a peptide analog of urotensin II, is a UT receptor agonist. [Orn8]-Urotensin II (human) increases intracellular calcium levels in HEK293 .

HY-172103

hCAI/II-IN-10	Carbonic Anhydrase	Others
hCAI/II-IN-10 (Compound 5d) is a human carbonic anhydrase I and II (hCA I and hCA II) inhibitor with IC₅₀ values are 4.32 and 3.89 nM respectively .

HY-P2643

Angiotensin I/II (4-8)	Endogenous Metabolite	Cardiovascular Disease
Angiotensin I/II (4-8), a major metabolite of Angiotensin II, is a C-terminal 4-8 pentapeptide .

HY-149002

Topoisomerase I/II inhibitor 4	Topoisomerase Apoptosis	Cancer
Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research .

HY-162381

Topoisomerase II inhibitor 19	Topoisomerase	Cancer
Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC₅₀ value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA .

HY-155645

Topoisomerase II inhibitor 15	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 15 (compound 2g) is a Topoisomerase II inhibitor. Topoisomerase II inhibitor 15 potently is an apoptotic inducer with greater selectivity against head and neck tumors .

HY-163118

Topoisomerase II inhibitor 17	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 17 (compound 4c) is an inhibitor of thiazolopyrimidine topoisomerase (Topoisomerase) Top II (IC₅₀: 0.23 μM). Topoisomerase II inhibitor 17 can significantly cause cell cycle disruption and apoptosis .

HY-P10108

Hexokinase II VDAC binding domain peptide, cell-permeable Hxk2VBD peptide, cell-permeable	Hexokinase	Neurological Disease
Hexokinase II VDAC binding domain peptide (Hxk2VBD peptide) is a cell-permeable hexokinase II VDAC binding domain. Hexokinase II VDAC binding domain peptide inhibits mitochondrial localization of hexokinase 2 (HXK2). Hexokinase II VDAC binding domain peptide inhibits neurotrophic factor-directed axon outgrowth .

HY-P2212

(Asn1,Val5)-Angiotensin II	Angiotensin Receptor	Inflammation/Immunology
Angiotensin amide ((Asn1,Val5)-Angiotensin II) is a potent vasoconstrictor. Angiotensin amide is a derivative of angiotensin II. Angiotensin amide can be used as a cardiac activator .

HY-P3771

p60c-src substrate II, phosphorylated	Src	Others
p60c-src substrate II，phosphorylated is a pentapeptide. p60c-src substrate II，phosphorylated is a p60c-src substrate II phosphorylated polypeptide. Protein phosphorylation is an important post-translationmodification of protein that is indispensible in biological regulations .

HY-147861

Topoisomerase II inhibitor 11	Topoisomerase Apoptosis	Cancer
Topoisomerase II inhibitor 11 (compound 3d) is a potent Topoisomerase II inhibitor, with an IC₅₀ of 2.89 μM. Topoisomerase II inhibitor 11 shows 92.46% inhibition on renal cancer cell line A498 with an IC₅₀ of 3.5 μM. Topoisomerase II inhibitor 11 causes cell cycle arrest at the G2/M phase leading to cell proliferation inhibition and pro-apoptotic activity .

HY-146316

Topoisomerase II inhibitor 6	Topoisomerase	Cancer
Topoisomerase II inhibitor 6 (Compound 5), a tryptanthrin derivative, is a potent and selective inhibitor of topoisomerase II. Topoisomerase II inhibitor 6 exhibits antiproliferative activity on different tumor cell lines. Topoisomerase II inhibitor 6 blocks the cell cycle of CCRF-CEM in the G2 phase and induces DNA DSB. Topoisomerase II inhibitor 6 has the potential for the research of cancer diseases .

HY-155693

Topoisomerase II inhibitor 16	Topoisomerase Parasite	Infection
Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research .

HY-P3570

Adipokinetic hormone II (Locusta migratoria) Lom-AKH-II	Endogenous Metabolite	Metabolic Disease
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II) is a insect adipokinetic hormone (AKH), enhances fat body cAMP levels in vitro. Insect adipokinetic hormones (AKHs) controls flight-directed mobilization of carbohydrate and lipid from fat body stores, which depends on AKH receptor(s) coupling to cAMP formation and glycogen phosphorylase activation via the stimulatory guanine nucleotide-binding protein (Gs) .

HY-174404

Topoisomerase II inhibitor 23	Topoisomerase Apoptosis Bcl-2 Family	Cancer
Topoisomerase II inhibitor 23 is a potent topoisomerase II inhibitor (IC₅₀= 0.94 μM). Topoisomerase II inhibitor 23 shows high selectivity and exceptional cytotoxic activity in MCF-7, HepG2, and HCT116 cells. Topoisomerase II inhibitor 23 induces cell cycle arrest at the G1 phase, leading to inhibition of cell proliferation. Topoisomerase II inhibitor 2 induces apoptosis by up-regulating the pro-apoptotic Bax level and down-regulating the anti-apoptotic Bcl-2 level.

HY-143402

Topoisomerase I/II inhibitor 2	Topoisomerase	Cancer
Topoisomerase I/II inhibitor 2 (compound 1a) is a potent Topoisomerase inhibitor (IC₅₀= 9.82 μM on Huh7 cells and 6.83 μM on LM9 cells). Topoisomerase I/II inhibitor 2 has dual inhibition on DNA topoisomerase I/II, also can obviously reduce the growth of xenograft tumor in mice model. Topoisomerase I/II inhibitor 2 has the potential value in researching liver cancer .

HY-13948

Angiotensin II human 145+ Cited Publications Angiotensin II; Ang II; DRVYIHPF	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-13948A

Angiotensin II human acetate 145+ Cited Publications Angiotensin II acetate; Ang II acetate; DRVYIHPF acetate	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-N5174

Azetomycin II Azet-II	Bacterial	Infection
Azetomycin II (Azet-II) has the effect of anti-Gram positive bacteria .

HY-W004643

Akardite II AK-II	Fungal Herbicide	Infection
Akardite II (AK-II) is a stabilizer for nitrocellulose (NC) propellants as it scavenges NO_x. Akardite II helps control a variety of plant pathogens and weeds, which can be used as fungicides and herbicides .

HY-E70038

Endoglycoceramidase II (EGCase II)	Endogenous Metabolite	Metabolic Disease
Endoglycoceramidase II (EGCase II) is an endo-β-glucosidase releasing the complete glycan from ceramide in glycosphingolipids. Endoglycoceramidase II Catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides in various glycosphingolipids .

HY-P2863

Deoxyribonuclease II DNase II	Endonuclease	Others
Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research .

HY-NP073

Maackia Amurensis Lectin II MAL II	Fluorescent Dye	Others
Maackia Amurensis Lectin II (MAL II) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin II (MAL II) is a biological material or organic compound that can be used in life science research .

HY-E70281

Recombinant endoglycoceramidase II rEGCase II	Biochemical Assay Reagents	Metabolic Disease
Recombinant endoglycoceramidase II (rEGCase II) is an endo-β-glucosidase releasing the complete glycan from ceramide in glycosphingolipids. Recombinant endoglycoceramidase II catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides in various glycosphingolipids .

HY-13948B

Angiotensin II human TFA 145+ Cited Publications Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Angiotensin II human TFA induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-NP069

Griffonia (Bandeiraea) Simplicifolia Lectin II GSL II	Fluorescent Dye	Others
Griffonia (Bandeiraea) Simplicifolia Lectin II (GSL II) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin II (GSL II) is a biological material or organic compound that can be used in life science research .

HY-P10486

AIP-II	Bacterial	Infection
AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aureus. AIP-II binds to AgrC-II receptor, regulates the virulence gene expression in Staphylococcus aureus. AIP-II is an antagonist for AgrC-I receptor .

HY-N7575

Lacto-N-fucopentaose II LNFP II	Endogenous Metabolite	Metabolic Disease Cancer
Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy .

HY-13948F1

Angiotensin II human, FAM-labeled Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled	Angiotensin Receptor	Cardiovascular Disease Endocrinology Cancer
Angiotensin II human, FAM-labeled (Angiotensin II, FAM-labeled) is a FAM labeled Angiotensin II human (HY-13948).

HY-N5195

Nocathiacin II Nocathiacine II	Bacterial	Infection
Nocathiacin II (Nocathiacine II) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-NP0181

Maackia Amurensis Lectin II (Biotinylated) MAL II (Biotinylated)	Fluorescent Dye	Others
Maackia Amurensis Lectin II (MAL II) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin II (MAL II) Biotinylated is a biological material or organic compound that can be used in life science research .

HY-P1763

Urechistachykinin II Uru-TK II	Bacterial	Infection
Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

HY-N14200

Maridomycin II	Antibiotic Bacterial	Infection
Maridomycin II is a macrolide antibiotic. Maridomycin II has the activity against Gram-positive bacteria and mycoplasma. Maridomycin II has the effect of protecting Gram-positive bacterial infection mice .

HY-N7542

Praeroside II	HCV Protease	Others
Praeroside II is an angular-type pyranocoumarm glycoside. Praeroside II can be isolated from the n-butanol-extracts of P. praeruptorum Dunn. Praeroside II can be used for pharmacological study .

HY-160519

Targocil-II	Bacterial Antibiotic	Infection
Targocil-II (Compound 2) is an ABC transporter inhibitor with a IC₅₀ value of 137 nM. Targocil-II prevents ATP hydrolysis by binding to allosteric sites of the TM domain. Targocil-II has (antibacterial) activity .

HY-122940R

Precocene II (Standard)	Others	Others
Precocene II (Standard) is the analytical standard of Precocene II. This product is intended for research and analytical applications. Precocene II is the insect antijuvenile hormone .

HY-108604

Bisindolylmaleimide II Bis II	PKC	Metabolic Disease Cancer
Bisindolylmaleimide II is a general inhibitor of all PKC subtypes .

HY-N6016

Bacopaside II 1 Publications Verification	Apoptosis Aquaporin	Cancer
Bacopaside II, an extract from the medicinal herb Bacopa monnieri. Bacopaside II is the inhibitor for AQP1 that exhibits anti-angiogenesis activity. Bacopaside II exhibits cytotoxicity and induces apoptosis in cancer cells .

HY-N13145

Azukisaponin II	Others	Infection
Azukisaponin II is a natural saponin. Azukisaponin II has anti-herpes virus activity and antioxidant activity .

HY-NP0150

Griffonia (Bandeiraea) Simplicifolia Lectin II (Fluorescein) GSL II (Fluorescein)	Fluorescent Dye	Others
Griffonia (Bandeiraea) Simplicifolia Lectin II (GSL II) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin II (GSL II) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-P5652

Bombolitin II	Bacterial	Infection
Bombolitin II is an antimicrobial peptide derived from bumblebee venom. Bombolitin II can lysate erythrocyte and liposome .

HY-13948F

Biotin-Ahx-Angiotensin II human Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF	Angiotensin Receptor	Others
Biotin-Ahx-Angiotensin II human (Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF) is a biological active peptide. (biotin labeled HY-13948)

HY-N3855

Erythrabyssin II	Autophagy Apoptosis	Cancer
Erythrabyssin II (EL-19) is a potent late-stage autophagy inhibitor that blocks the fusion of autophagosome and lysosome. Erythrabyssin II leads to the accumulation of autophagic substrates and does not impair lysosomal pH or lysosomal enzyme activity. Erythrabyssin II suppresses ovarian cancer organoid activity and induces apoptosis. Erythrabyssin II can be used for the study of ovarian cancer .

HY-N0698R

Crocin II (Standard)	Reference Standards NO Synthase COX Endogenous Metabolite	Neurological Disease Inflammation/Immunology Cancer
Crocin II (Standard) is the analytical standard of Crocin II. This product is intended for research and analytical applications. Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC₅₀ value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13948

Angiotensin II human 145+ Cited Publications Angiotensin II; Ang II; DRVYIHPF	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Cancer	Angiotensin Receptor Apoptosis
Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-N7575

Lacto-N-fucopentaose II LNFP II	Structural Classification Polysaccharides Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy .

HY-N6016

Bacopaside II 1 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Scrophulariaceae Plants Disease Research Fields Bacopa monnieri (Linn.) Wettst. Cancer	Apoptosis Aquaporin
Bacopaside II, an extract from the medicinal herb Bacopa monnieri. Bacopaside II is the inhibitor for AQP1 that exhibits anti-angiogenesis activity. Bacopaside II exhibits cytotoxicity and induces apoptosis in cancer cells .

HY-N13145

Azukisaponin II	Triterpenes Structural Classification Leguminosae Terpenoids Source classification Sophora japonica (L.) Schott Plants	Others
Azukisaponin II is a natural saponin. Azukisaponin II has anti-herpes virus activity and antioxidant activity .

HY-N5174

Azetomycin II Azet-II	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Azetomycin II (Azet-II) has the effect of anti-Gram positive bacteria .

HY-N5195

Nocathiacin II Nocathiacine II	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Nocathiacin II (Nocathiacine II) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF) .

HY-N14200

Maridomycin II	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Antibiotic Bacterial
Maridomycin II is a macrolide antibiotic. Maridomycin II has the activity against Gram-positive bacteria and mycoplasma. Maridomycin II has the effect of protecting Gram-positive bacterial infection mice .

HY-N7542

Praeroside II	Structural Classification Natural Products Chrysanthemum × morifolium (Ramat.) Hemsl. Umbelliferae Plants	HCV Protease
Praeroside II is an angular-type pyranocoumarm glycoside. Praeroside II can be isolated from the n-butanol-extracts of P. praeruptorum Dunn. Praeroside II can be used for pharmacological study .

HY-122940R

Precocene II (Standard)	Structural Classification Natural Products Animals Source classification	Others
Precocene II (Standard) is the analytical standard of Precocene II. This product is intended for research and analytical applications. Precocene II is the insect antijuvenile hormone .

HY-N3855

Erythrabyssin II	Structural Classification Leguminosae Source classification Phenols Polyphenols Plants Erythrina crista-galli Linn.	Autophagy Apoptosis
Erythrabyssin II (EL-19) is a potent late-stage autophagy inhibitor that blocks the fusion of autophagosome and lysosome. Erythrabyssin II leads to the accumulation of autophagic substrates and does not impair lysosomal pH or lysosomal enzyme activity. Erythrabyssin II suppresses ovarian cancer organoid activity and induces apoptosis. Erythrabyssin II can be used for the study of ovarian cancer .

HY-N0698R

Crocin II (Standard)	Structural Classification Terpenoids Source classification Rubiaceae Diterpenoids Plants Gardenia jasminoides Ellis	Reference Standards NO Synthase COX Endogenous Metabolite
Crocin II (Standard) is the analytical standard of Crocin II. This product is intended for research and analytical applications. Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC₅₀ value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2 .

HY-N11562

Aristololactam II	Structural Classification Alkaloids Stephania cepharantha Hayata Pyrrole Alkaloids Source classification Plants Menispermaceae	Others
Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .

HY-N2151R

Rhodojaponin II (Standard)	Structural Classification other families Terpenoids Source classification Diterpenoids Plants	Reference Standards Others
Rhodojaponin II (Standard) is the analytical standard of Rhodojaponin II. This product is intended for research and analytical applications. Rhodojaponin II is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity .

HY-N0698

Crocin II	Structural Classification Neurological Disease Classification of Application Fields Terpenoids Source classification Rubiaceae Diterpenoids Plants Gardenia jasminoides Ellis Inflammation/Immunology Disease Research Fields	NO Synthase COX Endogenous Metabolite
Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC₅₀ value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2 .

HY-N10532

Lacto-N-difucohexaose II LNDFH II ; Lacto-N-fucohexaose	Structural Classification Polysaccharides Classification of Application Fields Animals Other Diseases Disease Research Fields Saccharides	Others
Lacto-N-difucohexaose II (LNDFH II) is one of the oligosaccharides in human milk, it is important for infant health .

HY-N7751

Isotanshinone II	Structural Classification Eupatorium buniifolium Hook. & Arn. Terpenoids Labiatae Source classification Diterpenoids Plants	Others
Isotanshinone II is a natural product that can be isolated from Salvia glutinos. Isotanshinone II can be used to study Alzheimer's disease .

HY-N0332R

Ziyuglycoside II (Standard)	Triterpenes Structural Classification Sanguisorba officinalis Linn. Terpenoids Source classification Rosaceae Plants	Reference Standards Reactive Oxygen Species (ROS) Apoptosis
Ziyuglycoside II (Standard) is the analytical standard of Ziyuglycoside II. This product is intended for research and analytical applications. Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .

HY-N12141

Flaccidoside II	Structural Classification Polysaccharides Anemone flaccida Fr. Schmidt Source classification Ranunculaceae Plants Saccharides	Apoptosis
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .

HY-156711

Ternatumoside II	Structural Classification Flavonoids Flavones Crassulaceae Source classification Plants Rhodiola crenulata (HK. f. et.Thoms) H. Ohba	IFNAR
Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC₅₀s: 260.5 μM and 320.2 μM for DPPH and ABTS) .

HY-N6624

Skullcapflavone II	Flavonoids other families Classification of Application Fields Flavones Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Bacterial
Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG .

HY-122941

Viscidulin II	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Interleukin Related
Viscidulin II (FL6) is a flavone. Viscidulin II can be isolated from the root of Scutellaria baicalensis. Viscidulin II significantly suppresses P. acnes-induced IL-8 and IL-1β production in THP-1 cells .

HY-122920

Soyasaponin II	Triterpenes Structural Classification Classification of Application Fields Leguminosae Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields Glycine soja Sieb. Et Zucc.	HSV CMV Influenza Virus HIV NOD-like Receptor (NLR) YB-1
Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure .

HY-N6016R

Bacopaside II (Standard)	Triterpenes Structural Classification Terpenoids Source classification Scrophulariaceae Plants Bacopa monnieri (Linn.) Wettst.	Reference Standards Apoptosis Aquaporin
Bacopaside II (Standard) is the analytical standard of Bacopaside II. This product is intended for research and analytical applications. Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis .

HY-N12192

Ebenifoline E-II	Structural Classification Alkaloids Terpenoids Other Alkaloids Sesquiterpenes Source classification Celastraceae Euonymus laxiflorus Champ. ex Benth. Plants	Others
Ebenifoline E-II (Compound 2) is a sesquiterpene alkaloid derived from Euonymus laxiflorus. Ebenifoline E-II is cytotoxic .

HY-N12440

Sarmenoside II	Structural Classification Crassulaceae Source classification Sedum sarmentosum Bunge Phenols Polyphenols Plants	Others
Sarmenoside II is a flavonol glycoside with activity that inhibits lipid accumulation. Sarmenoside II inhibits albumin-oleate-induced lipid accumulation in HepG2 cells by approximately 30% at 100 μM.

HY-N8219

Isoarundinin II	Bletilla striata (Thunb. ex Murray) Rchb. f. Classification of Application Fields Orchidaceae Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Isoarundinin II is a stilbenoid compound .

HY-N13415

Cassiaglycoside II	Cassia tora (L.) Roxb. Structural Classification Leguminosae Source classification Phenols Polyphenols Plants	Others
Cassiaglycoside II is a natural product .

HY-N0332

Ziyuglycoside II 1 Publications Verification	Triterpenes Classification of Application Fields Sanguisorba officinalis Linn. Terpenoids Source classification Rosaceae Plants Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species (ROS) Apoptosis
Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .

HY-N0408R

Picroside II (Standard)	Structural Classification Iridoids Terpenoids Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell	Reference Standards NF-κB Reactive Oxygen Species (ROS) Apoptosis Influenza Virus
Picroside II (Standard) is the analytical standard of Picroside II. This product is intended for research and analytical applications. Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways . Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury. Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities .

HY-122940

Precocene II	Structural Classification Natural Products Animals Classification of Application Fields Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Precocene II is the insect antijuvenile hormone .

HY-N0202

Atractylenolide II 3 Publications Verification Asterolide	Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Astragalus caprinus L. Plants Compositae Disease Research Fields Cancer	ERK Apoptosis p38 MAPK Akt Src STAT
Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .

HY-N2891

Aristolactam A II Aristololactam A II	Piper longum Linn. Structural Classification Alkaloids Pyrrole Alkaloids Source classification Piperaceae Plants	Others
Aristolactam A II is a Aristolactam. Aristolactam a small group of compounds mainly found in the Aristolochiaceae .

HY-N0408

Picroside II 1 Publications Verification	Infection Structural Classification Iridoids Neurological Disease Classification of Application Fields Terpenoids Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields	NF-κB Reactive Oxygen Species (ROS) Apoptosis Influenza Virus
Picroside II is an antioxidant with oral activity that can reduce the production of ROS and protect the blood-brain barrier (BBB) after CI/R injury, offering neuroprotective effects. Picroside II has antioxidant, immune-regulating, antiviral properties, and inhibits apoptosis. Picroside II alleviates the inflammatory response in sepsis by suppressing the activation of the NLRP3 inflammasome and NF-κB pathways .

HY-152896

Ys-II	Structural Classification Natural Products Source classification Yucca gigantea Lem. Plants Asparagaceae Juss.	Fungal
Ys-II (Compound 1) is a spirostanol glycoside that can be isolated from the stem of Yucca elephantipe. Ys-II has antifungal activity against the growth of Candida albicans and Cryptococcus neoformans (IC₅₀: 5 and 6 μg/mL respectively) .

HY-N10318

Erigeside II Dictamnoside A	Structural Classification Dictamnus dasycarpus Turcz. Source classification Rutaceae Plants Saccharides Monosaccharides	Fungal
Erigeside II is a sesquiterpene glycoside found in the root bark of Dictamnus dasycarpus. Erigeside II stimulates the proliferation of T-cells .

HY-113767

Momordin II	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Plants Momordica charantia Linn.	DNA/RNA Synthesis
Momordin II, an oleanane-type triterpene glycoside, is a ribosome inactivating protein. Momordin II inhibits cell-free protein synthesis, releases adenine from rat liver ribosomes and from DNA, and has no RNase activity .

HY-130772

Filipin II	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Fungal
Filipin II is an antibiotic, which exhibits antifungal efficacy. Filipin II interacts with membrane sterols, leads to changes in membrane structure, inhibits Candida utilis and Saccharomyces cerevisiae with the MIC of 0.03 mg/L and 0.2 μg/L .

HY-N0202R

Atractylenolide II (Standard) Asterolide (Standard)	Structural Classification Terpenoids Sesquiterpenes Source classification Astragalus caprinus L. Plants Compositae	ERK Reference Standards Apoptosis p38 MAPK Src Akt STAT
Atractylenolide II (Standard) is the analytical standard of Atractylenolide II. This product is intended for research and analytical applications. Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .

HY-N0433

Astragaloside II 1 Publications Verification Astrasieversianin VIII	Triterpenes Structural Classification Classification of Application Fields Leguminosae Terpenoids Source classification Other Diseases Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants Disease Research Fields	Autophagy Interleukin Related HIF/HIF Prolyl-Hydroxylase SOD NF-κB
Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis .

HY-N8615

Peucedanocoumarin II	Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields	Others
Peucedanocoumarin II can induce rice resistance to blast disease .

HY-N8872

Arjunglucoside II	Triterpenes Structural Classification Terpenoids Combretaceae Source classification Terminalia fagifolia Mart. Plants	Others
Arjunglucoside II is a triterpenes that can be isolated from Terminalia fagifolia .

HY-N11139

Solidagolactone II	Structural Classification Terpenoids Source classification Diterpenoids Plants Compositae Glycyrrhiza lepidota Pursh	Others
Solidagolactone II is a chloroalkaned diterpene isolated from S. uirgaurea L .

HY-N12383

Officinalisnin-II	Structural Classification Polysaccharides Source classification Plants Saccharides Asparagaceae Juss. Asparagus filicinus D. Don	Others
Officinalisnin-II is a natural saponin found in the roots of Asparagus filicinus .

HY-111238

Butyrolactone II	Infection Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields	Endogenous Metabolite
Butyrolactone II is a fungal metabolite isolated from Aspergillus flavipes .

HY-N1204

Soyacerebroside II	Structural Classification Natural Products Source classification Aizoaceae Plants	Others
Soyacerebroside II is a calcium ionophoretic sphingoglycolipid that can be isolated from Soybean .

HY-N8785

Arvenin II	Triterpenes Structural Classification Terpenoids Source classification Cucurbitaceae Plants Citrullus colocynthis (L.) Schrad.	Others
Arvenin II is a bioactive compound, used to be isolated from Anagallis arvesnsis .

HY-N8662

Primulic acid II	Structural Classification Natural Products other families Classification of Application Fields Source classification Coniogramme japonica (Thunb.) Diels Plants Inflammation/Immunology Disease Research Fields Saccharides	Others
Primulic acid II is a saponin isolated from root extract of Primula sp .

HY-N3791

Durantoside II	Structural Classification Iridoids Terpenoids Verbenaceae Duranta erecta L. Source classification Plants	Others
Durantoside II is a Iridoids product that can be isolated from the herbs of Duranta repens .

HY-N10110

(±)-Phrymarolin II	Infection Structural Classification Classification of Application Fields Source classification Lignans Phrymaceae Phryma leptostachya subsp. asiatica (Hara)Kitamura Phenylpropanoids Plants Disease Research Fields	TMV
(±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.

HY-N11468

Homocapsaicin II	Structural Classification Monophenols Capsicum annuum L. Source classification Phenols Plants Solanaceae	Others
Homocapsaicin II is a pungent compound, that can be isolated from fruits of Capsicum annuum L .

Cat. No.	Product Name	Chemical Structure

HY-103005S

Ramelteon metabolite M-II-d3
Ramelteon metabolite M-II-d₃ is the deuterium labeled Ramelteon metabolite M-II. Ramelteon metabolite M-II is the major metabolite of Ramelteon, with IC₅₀s of 208 pM, 1470 pM for human melatonin receptors (MT1 or MT2). Ramelteon is a selective melatonin agonist .

HY-13948BS

Angiotensin II human-13C6,15N TFA

Angiotensin II human- ¹³C₆, ¹⁵N TFA (Ang II- ¹³C₆, ¹⁵N TFA) is ¹³C- and ¹⁵N-labeled Angiotensin II human (TFA) (HY-13948B). Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions .

HY-N0006S1

Demethoxycurcumin-d4
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties .

HY-17512S

Losartan-d4
Losartan-d₄ is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

HY-144145S

Hydroxy Pioglitazone (M-II)-d4
Hydroxy Pioglitazone (M-II)-d₄ is the deuterium labeled Hydroxy Pioglitazone (M-II) .

HY-W460871S

Apramycin-d7 acetate
Apramycin-d₇ (acetate) (Nebramycin II-d₇ (acetate)) is a deuterium labeled compound.

HY-N0006S

Demethoxycurcumin-d7
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-W750212

Acid Orange 7-13C6

Acid Orange 7- ¹³C₆ (Orange II- ¹³C₆) is the ¹³C-labeled Acid orange 7 (HY-N1442). Acid Orange 7 (Orange II; D&C Orange NO. 4) is an azo dye widely used in the textile, food and cosmetic industries. Acid Orange 7 is mainly used as a colorant by combining with fibers and other substances through azo bonds. Acid Orange 7 has a maximum absorption wavelength at 484-485 nm, and the concentration is measured using a UV-visible spectrophotometer. Acid Orange 7 is difficult to degrade and has a certain degree of toxicity. It is often used to study various sewage treatment technologies and photocatalytic degradation reactions, and to evaluate the removal effects of different treatment methods on organic pollutants .

HY-17512S3

Losartan-d2
Losartan-d₂ is the deuterium labeled Losartan . Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-17512S4

Losartan-d9
Losartan-d₉ is the deuterium labeled Losartan . Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-17512S1

Losartan-d3 Carboxylic Acid
Losartan-d₃ Carboxylic Acid is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-17512AS

Losartan-d6 hydrochloride
Losartan-d₆ hydrochloride is deuterated labeled Losartan potassium (HY-17512A). Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-B0202S3

Irbesartan-d7
Irbesartan-d₇ is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202AS

Irbesartan-d7 hydrochloride

Irbesartan-d₇ hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0109S

Dorzolamide-d5
Dorzolamide-d₅ is the deuterium labeled Dorzolamide. Dorzolamide (L671152) is a potent carbonic anhydrase II inhibitor, with IC₅₀ values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity .

HY-B0205S

Candesartan-d4
Candesartan-d₄ is the deuterium labeled Candesartan, which is an angiotensin II receptor antagonist.

HY-B0109AS

Dorzolamide-d3 hydrochloride
Dorzolamide-d₃ hydrochloride is deuterated labeled Dorzolamide hydrochloride (HY-B0109A). Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC₅₀ values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity .

HY-152041S

Sudan II-d6
Sudan Ⅱ-d6 is the deuterium labeled Sudan Ⅱ .

HY-B0109AS1

Dorzolamide-d5(hydrochloride)
Dorzolamide-d₅(hydrochloride) (L671152 hydrochloride-d₅) is deuterium labeled Dorzolamide (hydrochloride). Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC₅₀ values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity .

HY-B0588AS

Brinzolamide-d5 hydrochloride

Brinzolamide-d₅ (hydrochloride) is the deuterium labeled Brinzolamide hydrochloride . Brinzolamide (AL-4862) hydrochloride is a selective carbonic anhydrase II inhibitor with an IC₅₀ value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide hydrochloride can be used in glaucoma disease research .

HY-B0205S1

Candesartan-d5
Candesartan-d₅ is the deuterium labeled Candesartan. Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.

HY-117743S

Eprosartan-d3
Eprosartan-d₃ is the deuterium labeled Eprosartan. Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC₅₀s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively .

HY-12765S

Losartan-d4 (carboxylic acid)
Losartan-d₄ (carboxylic acid) is the deuterium labeled Losartan (EXP-3174), which is an angiotensin II receptor antagonist.

HY-117743S1

Eprosartan-d6
Eprosartan-d₆ is deuterated labeled Eprosartan (HY-117743). Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC₅₀s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively .

HY-B0588S

Brinzolamide-d5
Brinzolamide-d₅ is the deuterium labeled Brinzolamide. Brinzolamide (AL 4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.

HY-15552S

Podofilox-d6
Podofilox-d₆ is the deuterium labeled Podofilox. Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II .

HY-14914S

Azilsartan-d5
Azilsartan-d₅ is the deuterium labeled Azilsartan(TAK-536), which is a specific and potent angiotensin II type 1 receptor antagonist.

HY-B0202S

Irbesartan-d4
Irbesartan-d₄ is the deuterium labeled Irbesartan, which is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist.

HY-P1032S2

Angiotensin I-13C6,15N (human, mouse, rat) TFA
Angiotensin I-13C6,15N (human, mouse, rat) TFA is ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .

HY-17004S

Olmesartan-d4
Olmesartan-d₄ is the deuterium labeled Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure.

HY-18204S

Valsartan-d9
Valsartan-d₉ is deuterium labeled valsartan. Valsartan is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research .

HY-13635S

Finasteride-d9

Finasteride-d₉ is deuterium labeled Finasteride. Finasteride (MK-906) is a potent and competitive 5α-reductase inhibitor, with an IC₅₀ of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia .

HY-W014666S

Xanthurenic acid-d4
Xanthurenic acid-d₄ is the deuterium labeled Xanthurenic acid . Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus .

HY-B0202S1

Irbesartan-d6
Irbesartan-d₆ is the deuterium labeled Irbesartan. Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.

HY-137546S

Reduced Haloperidol-d4
Reduced Haloperidol-d₄ is the deuterium labeled Reduced Haloperidol .

HY-18204S2

Valsartan-d8
Valsartan-d₈ is the deuterium labeled Valsartan. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research .

HY-13562S

Banoxantrone-d12
Banoxantrone-d₁₂ is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.

HY-18204S1

Valsartan-d3
Valsartan-d₃ is the deuterium labeled Valsartan . Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research .

HY-18204S3

(Rac)-Valsartan-d9
(Rac)-Valsartan-d₉ is deuterium labeled Valsartan. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research .

HY-13562AS

Banoxantrone-d12 dihydrochloride
Banoxantrone-d₁₂ (dihydrochloride) is the deuterium labeled Banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.

HY-B0526S

Flumequine-13C3
Flumequine- ¹³C₃ is the ¹³C₃ labeled Flumequine. Flumequine (R-802) is a quinolone antibiotic, and acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).

HY-W653896

Alternariol-d2

Alternariol-d₂ is deuterium labeled Alternariol. Alternariol is an orally ingested mycotoxin produced by Alternaria, capable of inhibiting the activity of topoisomerase I and II (topoisomerase I, topoisomerase II). Alternariol has weak estrogenic (Estrogen Receptor/ERR) and androgen/antiandrogen (Androgen Receptor) effects. Alternariol can induce apoptosis, trigger cell cycle arrest, suppress innate immune responses, and exhibit anti-tumor activity. Alternariol has genotoxic, mutagenic, and endocrine-disrupting effects .

HY-17621S

Sparsentan-d5
Sparsentan-d₅ is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with K_is of 0.8 and 9.3 nM, respectively .

HY-N2362S2

DL-Alanine-d3

DL-Alanine-d₃ is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-N2362S5

DL-Alanine-15N

DL-Alanine- ¹⁵N is the ¹⁵N labeled DL-Alanine . DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-13502S

Mitoxantrone-d8
Mitoxantrone-d₈ (mitozantrone-d₈) is the deuterium labeled Mitoxantrone. Mitoxantrone is a topoisomerase II inhibitor and also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM .

HY-W707394

NOBA-d15
NOBA-d₁₅ is the deuterium labeled NOBA (HY-137799). NOBA is a synthetic chromogenic substrate that can be used to detect the enzyme activity of AplTX-II. NOBA can be used in the research of phospholipid hydrolysis .

HY-B1849S

Hexazinone-d6
Hexazinone-d₆ is the deuterium labeled Hexazinone . Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis .

HY-N2362S

DL-Alanine-13C-1

DL-Alanine- ¹³C-1 is the ¹³C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-N2362S1

DL-Alanine-13C-3

DL-Alanine- ¹³C-3 is the ¹³C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

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