TNF Receptor 2 Antibody (YA3868)

Cat. No.: HY-P84171: Data Sheet User Guide for Antibodies
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TNF Receptor 2 Antibody (YA3868) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TNF Receptor 2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	TNF Receptor 2 Antibody (YA3868) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TNF Receptor 2.
Background	CD120B is a receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, suggesting that it regulates TNF-alpha function by antagonizing its biological activity.
Gene ID	7133 [NCBI]
SwissProt ID	P20333
Synonyms	TNFRSF1B; p75; TBPII; TNFBR; TNFR2; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
Molecular Weight	Predicted band size: 48 kDa; Observed band size: 65 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Clonality	Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse
Dilution Ratio	WB: 1:500-1:2000; FC: 1:200-1:400; ELISA: 1:10000
Application	WB, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2b
Immunogen	Purified recombinant fragment of human CD120B (AA: extra 23-257) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

TNF Receptor 2 Antibody (YA3868) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TNF Receptor 2 Antibody (YA3868)

Biological Activity

Technical Parameters

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TNF Receptor 2 Antibody (YA3868) Related Classifications

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