TNF Receptor 2 Antibody (YA3868)

Cat. No.: HY-P84171: Data Sheet User Guide for Antibodies
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TNF Receptor 2 Antibody (YA3868) is a mouse-derived and non-conjugated IgG2b antibody, targeting to CD120B. It can be applicated for WB, FC, ELISA assays, in the background of human, mouse.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
Properties
Documentation

Description	TNF Receptor 2 Antibody (YA3868) is a mouse-derived and non-conjugated IgG2b antibody, targeting to CD120B. It can be applicated for WB, FC, ELISA assays, in the background of human, mouse.
Background	CD120B is a receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, suggesting that it regulates TNF-alpha function by antagonizing its biological activity.
Gene ID	7133 [NCBI]
SwissProt ID	P20333
Synonyms	TNFRSF1B; p75; TBPII; TNFBR; TNFR2; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
Molecular Weight	Predicted band size: 48 kDa; Observed band size: 65 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse
Dilution Ratio	WB: 1/500-1/2000; FC: 1/200-1/400; ELISA: 1/10000
Application	WB, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2b
Immunogen	Purified recombinant fragment of human CD120B (AA: extra 23-257) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

TNF Receptor 2 Antibody (YA3868) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TNF Receptor 2 Antibody (YA3868)

Biological Activity

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TNF Receptor 2 Antibody (YA3868) Related Classifications

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