2. Metabolic Enzyme/Protease Anti-infection
  3. Dipeptidyl Peptidase Fungal Bacterial
  4. Dioctatin A hydrochloride

Dioctatin A hydrochloride is a metabolite of Streptomyces and an inhibitor of human dipeptidyl aminopeptidase II. Dioctatin A hydrochloride can inhibit aflatoxin production by Aspergillus parasiticus with an IC50 of 4.0 μM. Dioctatin A hydrochloride can reduce the mRNA levels of aflatoxin biosynthetic genes and the regulatory gene aflR, inhibit conidiation and decrease the mRNA level of the brlA gene, and also promote kojic acid production. In addition, Dioctatin A hydrochloride can inhibit sterigmatocystin production. Dioctatin A hydrochloride has pleiotropic regulatory effects on the production and differentiation of fungal secondary metabolites.

For research use only. We do not sell to patients.

Dioctatin A hydrochloride Chemical Structure

Dioctatin A hydrochloride Chemical Structure

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Dioctatin A hydrochloride Related Antibodies

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Description

Dioctatin A hydrochloride is a metabolite of Streptomyces and an inhibitor of human dipeptidyl aminopeptidase II. Dioctatin A hydrochloride can inhibit aflatoxin production by Aspergillus parasiticus with an IC50 of 4.0 μM. Dioctatin A hydrochloride can reduce the mRNA levels of aflatoxin biosynthetic genes and the regulatory gene aflR, inhibit conidiation and decrease the mRNA level of the brlA gene, and also promote kojic acid production. In addition, Dioctatin A hydrochloride can inhibit sterigmatocystin production. Dioctatin A hydrochloride has pleiotropic regulatory effects on the production and differentiation of fungal secondary metabolites[1].

Molecular Weight

434.01

Formula

C21H40ClN3O4
SMILES

O=C(C[C@@H](NC([C@@H]([C@H](CCCCC)N)C)=O)CCCCC)N/C(C(O)=O)=C/C.Cl
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Dioctatin A hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dioctatin ADipeptidyl PeptidaseFungalBacterialDPPStreptomycesAspergillus parasiticusfungal secondary metabolitesInhibitorinhibitorinhibit

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