Cyclam

Cat. No.: HY-D0179 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Cyclam is a metal chelator that forms metal complexes with a variety of metal ions. Cyclam metal complexes exhibits anti-HIV (such as AMD3100), nitric oxide (NO) releasing and scavenging (such as Zn(II)-Cyclam and Ru(II)-Cyclam), and SOD mimetic (such as Mn(III)-Cyclam and Zn(II)-Cyclam) activities.

For research use only. We do not sell to patients.

Cyclam Chemical Structure

CAS No. : 295-37-4

Size	Stock	Quantity
100 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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This product is a controlled substance and not for sale in your territory.

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Description

Molecular Weight

200.33

Formula

C₁₀H₂₄N₄

CAS No.

295-37-4

Appearance

Solid

Color

White to yellow

SMILES

N1CCNCCCNCCNCCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : 20 mg/mL (99.84 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9918 mL	24.9588 mL	49.9176 mL
5 mM	0.9984 mL	4.9918 mL	9.9835 mL
10 mM	0.4992 mL	2.4959 mL	4.9918 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.0%

Select Batch:

Data Sheet (268 KB) SDS (393 KB)

COA (247 KB) HNMR (128 KB) MS (75 KB)

Handling Instructions (2659 KB)

References

[1]. Liang X, et al., Cyclam complexes and their applications in medicine. Chem Soc Rev. 2004 May 10;33(4):246-66. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.9918 mL	24.9588 mL	49.9176 mL	124.7941 mL
	5 mM	0.9984 mL	4.9918 mL	9.9835 mL	24.9588 mL
	10 mM	0.4992 mL	2.4959 mL	4.9918 mL	12.4794 mL
	15 mM	0.3328 mL	1.6639 mL	3.3278 mL	8.3196 mL
	20 mM	0.2496 mL	1.2479 mL	2.4959 mL	6.2397 mL
	25 mM	0.1997 mL	0.9984 mL	1.9967 mL	4.9918 mL
	30 mM	0.1664 mL	0.8320 mL	1.6639 mL	4.1598 mL
	40 mM	0.1248 mL	0.6240 mL	1.2479 mL	3.1199 mL
	50 mM	0.0998 mL	0.4992 mL	0.9984 mL	2.4959 mL
	60 mM	0.0832 mL	0.4160 mL	0.8320 mL	2.0799 mL
	80 mM	0.0624 mL	0.3120 mL	0.6240 mL	1.5599 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Cyclam Related Classifications

Infection Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclam295-37-4Biochemical Assay Reagentsmetal chelatorInhibitorinhibitorinhibit

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Cyclam

Cyclam Related Antibodies

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