Flutolanil

Cat. No.: HY-B2011 Purity: 99.44%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Flutolanil is a broad-spectrum fungicide. Flutolanil inhibits mycelial oxygen consumption and succinate dehydrogenase in mitochondria Complex II. Flutolanil causes endocrine disruption and reproductive disorders in zebrafish after long-term exposure. Flutolanil can be used to control the fungal pathogens induced plant disease.

For research use only. We do not sell to patients.

Flutolanil Chemical Structure

CAS No. : 66332-96-5

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	Get quote
5 g	Get quote

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* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Flutolanil:

Flutolanil (Standard) Get quote

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Description

Molecular Weight

323.31

Formula

C₁₇H₁₆F₃NO₂

CAS No.

66332-96-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C(C(F)(F)F)C=CC=C1)NC2=CC(OC(C)C)=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (309.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0930 mL	15.4650 mL	30.9301 mL
5 mM	0.6186 mL	3.0930 mL	6.1860 mL
10 mM	0.3093 mL	1.5465 mL	3.0930 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 5 mg/mL (15.47 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.44%

Select Batch:

Data Sheet (270 KB) SDS (398 KB)

COA (246 KB) HNMR (266 KB) LCMS (100 KB)

Handling Instructions (2659 KB)

References

[1]. Teng M, et al., Chronic exposure of zebrafish (Danio rerio) to flutolanil leads to endocrine disruption and reproductive disorders. Environ Res. 2020 May;184:109310. [Content Brief]

[2]. Motoba K, et al., Mode of antifungal action and selectivity of flutolanil[J]. Agricultural and biological chemistry, 1988, 52(6): 1445-1449.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0930 mL	15.4650 mL	30.9301 mL	77.3252 mL
	5 mM	0.6186 mL	3.0930 mL	6.1860 mL	15.4650 mL
	10 mM	0.3093 mL	1.5465 mL	3.0930 mL	7.7325 mL
	15 mM	0.2062 mL	1.0310 mL	2.0620 mL	5.1550 mL
	20 mM	0.1547 mL	0.7733 mL	1.5465 mL	3.8663 mL
	25 mM	0.1237 mL	0.6186 mL	1.2372 mL	3.0930 mL
	30 mM	0.1031 mL	0.5155 mL	1.0310 mL	2.5775 mL
	40 mM	0.0773 mL	0.3866 mL	0.7733 mL	1.9331 mL
	50 mM	0.0619 mL	0.3093 mL	0.6186 mL	1.5465 mL
	60 mM	0.0516 mL	0.2578 mL	0.5155 mL	1.2888 mL
	80 mM	0.0387 mL	0.1933 mL	0.3866 mL	0.9666 mL
	100 mM	0.0309 mL	0.1547 mL	0.3093 mL	0.7733 mL

Flutolanil Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flutolanil66332-96-5FungalMitochondrial MetabolismSuccinate DehydrogenaseRhizoctonia solaniCorticium rolfsiiTyphulaGymnosporangiumrice sheath blightInhibitorinhibitorinhibit

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Flutolanil

Other Forms of Flutolanil:

Flutolanil Related Antibodies

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References

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