|
4T1
|
IC50 |
|
Antiproliferative activity against mouse 4T1 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against mouse 4T1 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
|
[PMID: 33586434]
|
|
4T1
|
IC50 |
|
Antiproliferative activity against mouse 4T1 cells assessed as cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against mouse 4T1 cells assessed as cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36097406]
|
|
4T1
|
IC50 |
|
Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
4T1
|
IC50 |
4.76 μM
Compound: Vorinostat
|
Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against mouse 4T1 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
518A2
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human 518A2 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human 518A2 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
518A2
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human 518A2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human 518A2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
786-0
|
GI50 |
3.2 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human 786-0 cells after 72 hrs by MTS assay
Growth inhibition of human 786-0 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
A-375
|
IC50 |
1.4 μM
Compound: Vorinostat
|
Antiproliferative activity against human A-375 cells
Antiproliferative activity against human A-375 cells
|
[PMID: 37875056]
|
|
A-375
|
IC50 |
|
Antiproliferative activity against human A375 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human A375 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
|
[PMID: 31991336]
|
|
A-375
|
IC50 |
|
Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
A-375
|
IC50 |
|
Cytotoxicity against human A375 cells assessed as growth inhibition after 72 hrs by MTS assay
Cytotoxicity against human A375 cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 28131715]
|
|
A-431
|
GI50 |
4.48 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human A431 cells by MTT assay
Growth inhibition of human A431 cells by MTT assay
|
[PMID: 23601706]
|
|
A-431
|
IC50 |
|
Antiproliferative activity against human A-431 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human A-431 cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
A-431
|
IC50 |
1.47 μM
Compound: Vorinostat
|
Antiproliferative activity against human A431 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human A431 cells incubated for 72 hrs by MTT assay
|
[PMID: 33493830]
|
|
A-431
|
IC50 |
|
Antiproliferative activity against human A431 cells expressing EGFR/HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human A431 cells expressing EGFR/HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 27769671]
|
|
A-431
|
IC50 |
3.13 μM
Compound: Vorinostat
|
Antiproliferative activity against human A-431 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human A-431 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37875056]
|
|
A-431
|
IC50 |
|
Antiproliferative activity against human A431 cells after 72 hrs by SRB assay
Antiproliferative activity against human A431 cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
A-431
|
IC50 |
|
Cytotoxicity against human A-431 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human A-431 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
A-431
|
IC50 |
|
Cytotoxicity against human A431 cells
Cytotoxicity against human A431 cells
|
[PMID: 17691763]
|
|
A-431
|
IC50 |
|
Cytotoxicity against human A431 cells overexpressing EGFR by resazurin dye reduction assay
Cytotoxicity against human A431 cells overexpressing EGFR by resazurin dye reduction assay
|
[PMID: 21080629]
|
|
A-431
|
IC50 |
5.13 μM
Compound: Zolinza, SAHA
|
Antiproliferative activity against human A431 cells after 48 hrs by MTT assay
Antiproliferative activity against human A431 cells after 48 hrs by MTT assay
|
[PMID: 22698782]
|
|
A20
|
IC50 |
|
In vitro for anti-HDAC1 (Histone deacetylase 1) activity in mouse A20 cells
In vitro for anti-HDAC1 (Histone deacetylase 1) activity in mouse A20 cells
|
[PMID: 11960489]
|
|
A20
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against mouse A20 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against mouse A20 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
A2780
|
CC50 |
|
Antiproliferative activity against human A2780 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human A2780 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19441846]
|
|
A2780
|
EC50 |
|
Inhibition of HDAC1/2/3 in human A2780S cells assessed as histone H3 acetylation incubated for 6 hrs by cytoblot assay
Inhibition of HDAC1/2/3 in human A2780S cells assessed as histone H3 acetylation incubated for 6 hrs by cytoblot assay
|
[PMID: 27186676]
|
|
A2780
|
EC50 |
|
Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assay
Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assay
|
[PMID: 27186676]
|
|
A2780
|
GI50 |
3150 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human A2780 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human A2780 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
A2780
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
A2780
|
IC50 |
0.43 μM
Compound: 3; SAHA
|
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36449947]
|
|
A2780
|
IC50 |
0.44 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in cisplatin resistant human A2780 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in cisplatin resistant human A2780 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
A2780
|
IC50 |
0.53 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in human A2780 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in human A2780 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
A2780
|
IC50 |
0.64 μM
Compound: Vorinostat
|
Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further incubation for 3 hrs by microplate reader based fluorescence assay
Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and further incubation for 3 hrs by microplate reader based fluorescence assay
|
[PMID: 31431326]
|
|
A2780
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
A2780
|
IC50 |
|
Inhibition of HDAC in human A2780 cells
Inhibition of HDAC in human A2780 cells
|
[PMID: 31787463]
|
|
A2780
|
IC50 |
0.96 μM
Compound: Vorinostat
|
Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay
Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay
|
[PMID: 31762274]
|
|
A2780
|
IC50 |
1.16 μM
Compound: Vorinostat
|
Antiproliferative activity against human A2780 cells after 72 hrs by microplate reader based MTT assay
Antiproliferative activity against human A2780 cells after 72 hrs by microplate reader based MTT assay
|
[PMID: 31431326]
|
|
A2780
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human A2780 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human A2780 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells
Antiproliferative activity against human A2780 cells
|
[PMID: 20451378]
|
|
A2780
|
IC50 |
1.62 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human A2780 cells after 96 hrs by celltiter 96 assay
Antiproliferative activity against human A2780 cells after 96 hrs by celltiter 96 assay
|
[PMID: 21634430]
|
|
A2780
|
IC50 |
|
Cytotoxicity against human A2780 cells
Cytotoxicity against human A2780 cells
|
[PMID: 23906422]
|
|
A2780
|
IC50 |
|
Cytotoxicity against human A2780 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human A2780 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31787463]
|
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells after 72 hrs by SRB assay
Antiproliferative activity against human A2780 cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human A2780 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
A2780
|
IC50 |
2.42 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
A2780
|
IC50 |
2.42 μM
Compound: Vorinostat
|
Cytotoxicity against human A2780 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
Cytotoxicity against human A2780 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
|
[PMID: 31762274]
|
|
A2780
|
IC50 |
2.42 μM
Compound: Vorinostat
|
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human A2780 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33360560]
|
|
A2780
|
IC50 |
2600 nM
Compound: 1, vorinostat
|
Antiproliferative activity against human A2780 cells by CellTiter-Blue cell viability assay
Antiproliferative activity against human A2780 cells by CellTiter-Blue cell viability assay
|
[PMID: 18370373]
|
|
A2780
|
IC50 |
3.12 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against cisplatin resistant human A2780 cells after 72 hrs by MTT assay
Cytotoxicity against cisplatin resistant human A2780 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
A2780
|
IC50 |
380 nM
Compound: Vorinostat
|
Antiproliferative activity against human A2780 cells
Antiproliferative activity against human A2780 cells
|
[PMID: 37875056]
|
|
A2780
|
IC50 |
|
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37116762]
|
|
A2780
|
IC50 |
|
Cytotoxicity against human A2780S cells assessed as growth inhibition after 24 hrs by MTT assay
Cytotoxicity against human A2780S cells assessed as growth inhibition after 24 hrs by MTT assay
|
[PMID: 27186676]
|
|
A2780
|
IC50 |
|
Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
A2780S
|
IC50 |
|
Antiproliferative activity against human A2780S cells after 72 hrs by MTT assay
Antiproliferative activity against human A2780S cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
A498
|
GI50 |
|
Antiproliferative activity against human A498 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human A498 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
A498
|
GI50 |
1.6 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human A498 cells after 72 hrs by MTS assay
Growth inhibition of human A498 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
A498
|
IC50 |
|
Antiproliferative activity against human A498 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
Antiproliferative activity against human A498 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
|
[PMID: 34111829]
|
|
A549
|
CC50 |
|
Antiproliferative activity against human P53 expressing A549 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human P53 expressing A549 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19441846]
|
|
A549
|
EC50 |
|
Inhibition of HDAC6 in human A549 cells assessed as induction of tubulin acetylation after 17 to 18 hrs by ELISA
Inhibition of HDAC6 in human A549 cells assessed as induction of tubulin acetylation after 17 to 18 hrs by ELISA
|
[PMID: 25734520]
|
|
A549
|
EC50 |
|
Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assay
Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assay
|
[PMID: 25238284]
|
|
A549
|
EC50 |
12 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells measured after 72 hrs by WST1 assay
Antiproliferative activity against human A549 cells measured after 72 hrs by WST1 assay
|
[PMID: 27597246]
|
|
A549
|
EC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 23820574]
|
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
|
[PMID: 21712146]
|
|
A549
|
GI50 |
1.02 μM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
|
[PMID: 31655430]
|
|
A549
|
GI50 |
1.02 μM
Compound: 1; SAHA
|
Growth inhibition of human A549 cells incubated for 48 hrs by SRB assay
Growth inhibition of human A549 cells incubated for 48 hrs by SRB assay
|
[PMID: 32058238]
|
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
Antiproliferative activity against human A549 cells after 48 hrs by SRB assay
|
[PMID: 27344487]
|
|
A549
|
GI50 |
1.02 μM
Compound: SAHA; 1
|
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 29567459]
|
|
A549
|
GI50 |
1.6 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human A549/ATCC cells after 72 hrs by MTS assay
Growth inhibition of human A549/ATCC cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
A549
|
GI50 |
1.73 μM
Compound: 1; SAHA
|
Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28395150]
|
|
A549
|
GI50 |
1.78 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human A549 cells by MTT assay
Growth inhibition of human A549 cells by MTT assay
|
[PMID: 23601706]
|
|
A549
|
GI50 |
1.85 μM
Compound: 1, SAHA
|
Growth inhibition of human A549 cells after 48 hrs by SRB assay
Growth inhibition of human A549 cells after 48 hrs by SRB assay
|
[PMID: 22439863]
|
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 28629630]
|
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
|
[PMID: 31924504]
|
|
A549
|
GI50 |
3.1 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human A549 cells after 72 hrs by MTT assay
Growth inhibition of human A549 cells after 72 hrs by MTT assay
|
[PMID: 22435669]
|
|
A549
|
GI50 |
3.13 μM
Compound: 1, SAHA
|
Growth inhibition of human A549 cells after 96 hrs by MTT assay
Growth inhibition of human A549 cells after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
A549
|
GI50 |
5.02 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells after 96 hrs by MTT assay
Antiproliferative activity against human A549 cells after 96 hrs by MTT assay
|
[PMID: 29500130]
|
|
A549
|
GI50 |
5.27 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
|
[PMID: 34500130]
|
|
A549
|
GI50 |
5700 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human A549 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human A549 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
A549
|
GI50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 19822426]
|
|
A549
|
GI50 |
> 410 nM
Compound: Vorinostat
|
Cytotoxicity against human A549 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
A549
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 37563016]
|
|
A549
|
IC50 |
0.493 μM
Compound: Vorinostat
|
Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
|
[PMID: 34237620]
|
|
A549
|
IC50 |
0.6 mM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells after 2 days by MTT assay
Antiproliferative activity against human A549 cells after 2 days by MTT assay
|
[PMID: 19608304]
|
|
A549
|
IC50 |
0.61 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells
Antiproliferative activity against human A549 cells
|
[PMID: 37875056]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells expressing EGFR and KRAS mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against human A549 cells expressing EGFR and KRAS mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 27769671]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability
Antiproliferative activity against human A549 cells assessed as reduction in cell viability
|
[PMID: 35643262]
|
|
A549
|
IC50 |
0.68 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
0.69 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 21733698]
|
|
A549
|
IC50 |
0.74 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 21476600]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs
Antiproliferative activity against human A549 cells after 48 hrs
|
[PMID: 20576572]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by resazurin based microplate reader analysis
Antiproliferative activity against human A549 cells incubated for 48 hrs by resazurin based microplate reader analysis
|
[PMID: 37647727]
|
|
A549
|
IC50 |
|
Anti-proliferative activity against human A549 cells after 48 hrs by MTT assay
Anti-proliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 28947154]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
|
[PMID: 20855208]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
|
[PMID: 35238576]
|
|
A549
|
IC50 |
1.02 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
|
[PMID: 23644210]
|
|
A549
|
IC50 |
1.079 μM
Compound: vorinostat
|
Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
|
[PMID: 26629860]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human A549 cells after 72 hrs by CellTiter-Glo assay
|
[PMID: 30245394]
|
|
A549
|
IC50 |
1.08 μM
Compound: SAHA, Vorinostat
|
Antiproliferative activity against human A549 cells after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human A549 cells after 72 hrs by CellTiter-Glo assay
|
[PMID: 23792316]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability
Antiproliferative activity against human A549 cells assessed as reduction in cell viability
|
[PMID: 34314844]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 36549114]
|
|
A549
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
|
[PMID: 37086699]
|
|
A549
|
IC50 |
1.35 μM
Compound: Vorinostat
|
Cytotoxicity against human A549 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
A549
|
IC50 |
1.54 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 24766560]
|
|
A549
|
IC50 |
1.62 μM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
A549
|
IC50 |
1.65 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
|
[PMID: 25874326]
|
|
A549
|
IC50 |
1.65 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 25953722]
|
|
A549
|
IC50 |
|
Dark toxicity in human A549 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
Dark toxicity in human A549 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
|
[PMID: 33744687]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 35858522]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 29223096]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
|
[PMID: 32738414]
|
|
A549
|
IC50 |
|
Phototoxicity in human A549 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
Phototoxicity in human A549 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
|
[PMID: 33744687]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37057760]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
|
[PMID: 38964169]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
|
[PMID: 17691763]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells overexpressing HDAC by resazurin dye reduction assay
Cytotoxicity against human A549 cells overexpressing HDAC by resazurin dye reduction assay
|
[PMID: 21080629]
|
|
A549
|
IC50 |
1.91 μM
Compound: XII; SAHA
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
A549
|
IC50 |
12.5 nM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
|
[PMID: 32679451]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells
Antiproliferative activity against human A549 cells
|
[PMID: 18247554]
|
|
A549
|
IC50 |
|
Antiproliferative activity in human A549 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
Antiproliferative activity in human A549 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
|
[PMID: 32061484]
|
|
A549
|
IC50 |
17.9 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23707260]
|
|
A549
|
IC50 |
1746.95 nM
Compound: SAHA
|
Antiproliferative activity against human A549 cells after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells after 72 hrs by SRB assay
|
[PMID: 30115492]
|
|
A549
|
IC50 |
1800 nM
Compound: 1, SAHA
|
Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue viability assay
Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue viability assay
|
[PMID: 18809328]
|
|
A549
|
IC50 |
1800 nM
Compound: 1, SAHA
|
Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human A549 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19410459]
|
|
A549
|
IC50 |
1800 nM
Compound: 1, vorinostat
|
Antiproliferative activity against human A549 cells by CellTiter-Blue cell viability assay
Antiproliferative activity against human A549 cells by CellTiter-Blue cell viability assay
|
[PMID: 18370373]
|
|
A549
|
IC50 |
1862 nM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
A549
|
IC50 |
2.01 μM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human A549 cells after 72 hrs by CCK8 assay
|
[PMID: 30045621]
|
|
A549
|
IC50 |
|
Antiproliferative against human A549 cells assessed as reduction in cell viability by MTT assay
Antiproliferative against human A549 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 33045329]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by alamar-blue cell viability assay
Cytotoxicity against human A549 cells after 72 hrs by alamar-blue cell viability assay
|
[PMID: 19301902]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30525585]
|
|
A549
|
IC50 |
2.27 μM
Compound: Vorinostat
|
Cytotoxicity against human A549 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
Cytotoxicity against human A549 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
|
[PMID: 23829483]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 28987602]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
|
[PMID: 31413795]
|
|
A549
|
IC50 |
2.43 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
2.47 μM
Compound: 1; SAHA
|
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
|
[PMID: 36215854]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells
Antiproliferative activity against human A549 cells
|
[PMID: 32961382]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
A549
|
IC50 |
2.63 μM
Compound: 4; SAHA
|
Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay
|
[PMID: 29670692]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells measured after 48 hrs by MTT assay
|
[PMID: 35041998]
|
|
A549
|
IC50 |
2.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells by CCK8 assay
Antiproliferative activity against human A549 cells by CCK8 assay
|
[PMID: 30660827]
|
|
A549
|
IC50 |
2.92 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
2.93 μM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by SRB assay
|
[PMID: 32180916]
|
|
A549
|
IC50 |
2651.1 nM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
|
[PMID: 32679451]
|
|
A549
|
IC50 |
27.8 μM
Compound: Zolinza, SAHA
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 22698782]
|
|
A549
|
IC50 |
3 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 96 hrs by resazurin assay
Antiproliferative activity against human A549 cells incubated for 96 hrs by resazurin assay
|
[PMID: 32435375]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
A549
|
IC50 |
|
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 34634618]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs
Antiproliferative activity against human A549 cells after 48 hrs
|
[PMID: 24262004]
|
|
A549
|
IC50 |
3.7 μM
Compound: Vorinostat
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
A549
|
IC50 |
|
Inhibition of human A549 cell proliferation after 48 hrs by MTT assay
Inhibition of human A549 cell proliferation after 48 hrs by MTT assay
|
[PMID: 23493449]
|
|
A549
|
IC50 |
3.9 μM
Compound: SA, SAHA
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 38452727]
|
|
A549
|
IC50 |
4.12 μM
Compound: 1; SAHA
|
Cytotoxicity against human A549 cells assessed as decrease in cell viability measured after 72 hrs by CellTiter-Glo Luminescent assay
Cytotoxicity against human A549 cells assessed as decrease in cell viability measured after 72 hrs by CellTiter-Glo Luminescent assay
|
[PMID: 31223439]
|
|
A549
|
IC50 |
4.25 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 33493830]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34624191]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 29348808]
|
|
A549
|
IC50 |
4.4 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
|
[PMID: 35608269]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 23570542]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
10.1039/C4MD00203B
|
|
A549
|
IC50 |
476.86 nM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells measured after 48 hrs by sulforhodamine-B assay
Antiproliferative activity against human A549 cells measured after 48 hrs by sulforhodamine-B assay
|
[PMID: 27886544]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 28057407]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells by MTT assay
Antiproliferative activity against human A549 cells by MTT assay
|
[PMID: 31546197]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26149591]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 24 to 48 hrs by CCK-8 assay
Antiproliferative activity against human A549 cells incubated for 24 to 48 hrs by CCK-8 assay
|
[PMID: 39145486]
|
|
A549
|
IC50 |
5.74 μM
Compound: I-1; SAHA
|
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 35245830]
|
|
A549
|
IC50 |
6.74 μM
Compound: SAHA; 6
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by celltiter-glo luminescent assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by celltiter-glo luminescent assay
|
[PMID: 39178382]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells incubated for 24 hrs by CCK8 assay
Antiproliferative activity against human A549 cells incubated for 24 hrs by CCK8 assay
|
[PMID: 32247729]
|
|
A549
|
IC50 |
7.32 μM
Compound: 1; SAHA
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
|
[PMID: 34656899]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
|
[PMID: 35043615]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells measured after 72 hrs
Antiproliferative activity against human A549 cells measured after 72 hrs
|
[PMID: 35697181]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
A549
|
IC50 |
80.3 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against SAHA-resistant human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against SAHA-resistant human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 23707260]
|
|
A549
|
IC50 |
9.13 μM
Compound: Vorinostat
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
|
[PMID: 35255412]
|
|
A549
|
IC50 |
|
Anticancer activity against human A549 cells assessed as inhibition of cell growth measured for 48 hrs by MTT assay
Anticancer activity against human A549 cells assessed as inhibition of cell growth measured for 48 hrs by MTT assay
|
[PMID: 38897139]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
|
[PMID: 34116381]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 35272009]
|
|
A549
|
IC50 |
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
A549
|
IC50 |
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
ACHN
|
GI50 |
|
Growth inhibition of human ACHN cells after 21 hrs by MTT assay
Growth inhibition of human ACHN cells after 21 hrs by MTT assay
|
[PMID: 17662606]
|
|
ACHN
|
GI50 |
0.73 μM
Compound: 1, SAHA
|
Growth inhibition of ACHN cells by SRB assay
Growth inhibition of ACHN cells by SRB assay
|
[PMID: 17477518]
|
|
ACHN
|
GI50 |
0.73 μM
Compound: 2, SAHA
|
Antiproliferative activity against human ACHN cells by SRB assay
Antiproliferative activity against human ACHN cells by SRB assay
|
[PMID: 16723227]
|
|
ACHN
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human ACHN cells after 72 hrs by MTS assay
Growth inhibition of human ACHN cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
ACHN
|
GI50 |
2.22 μM
Compound: 2, SAHA
|
Growth inhibition of human ACHN cells by SRB assay
Growth inhibition of human ACHN cells by SRB assay
|
[PMID: 17904843]
|
|
ACHN
|
GI50 |
4.22 μM
Compound: 1, SAHA
|
Growth inhibition of human ACHN cells
Growth inhibition of human ACHN cells
|
[PMID: 20850971]
|
|
ACHN
|
GI50 |
4.22 μM
Compound: 1, SAHA, Zolinza, Vorinostat
|
Cytotoxicity against human ACHN cells assessed as growth inhibition by SRB assay
Cytotoxicity against human ACHN cells assessed as growth inhibition by SRB assay
|
[PMID: 23163332]
|
|
ACHN
|
GI50 |
|
Growth inhibition of human ACHN cells after 5 days by sulforhodamine B assay
Growth inhibition of human ACHN cells after 5 days by sulforhodamine B assay
|
[PMID: 25811792]
|
|
ACHN
|
GI50 |
|
Growth inhibition of human ACHN cells measured after 5 days by sulforhodamine-B assay
Growth inhibition of human ACHN cells measured after 5 days by sulforhodamine-B assay
|
[PMID: 28011426]
|
|
ACHN
|
IC50 |
|
Antiproliferative activity against human ACHN cells after 72 hrs by MTT assay
Antiproliferative activity against human ACHN cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
AGS
|
IC50 |
|
Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34628244]
|
|
AGS
|
IC50 |
|
Antiproliferative activity against human AGS cells after 72 hrs by MTT assay
Antiproliferative activity against human AGS cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
AGS
|
IC50 |
|
Antiproliferative activity against human AGS cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human AGS cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
AML12
|
IC50 |
|
Cytotoxicity against AML12 cells incubated for 72 hrs measured by MTT assay
Cytotoxicity against AML12 cells incubated for 72 hrs measured by MTT assay
|
[PMID: 37498552]
|
|
ASPC1
|
GI50 |
2.09 μM
Compound: 1, SAHA
|
Growth inhibition of human Aspc-1 cells after 96 hrs by MTT assay
Growth inhibition of human Aspc-1 cells after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
ASPC1
|
GI50 |
5.44 μM
Compound: 1; SAHA
|
Growth inhibition of human AsPC1 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human AsPC1 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28395150]
|
|
ASPC1
|
IC50 |
0.69 μg/mL
Compound: SAHA
|
Cytotoxicity against human AsPC1 cells
Cytotoxicity against human AsPC1 cells
|
[PMID: 22036991]
|
|
ASPC1
|
IC50 |
|
Cytotoxicity against human AsPC1 cells
Cytotoxicity against human AsPC1 cells
|
[PMID: 17691763]
|
|
ASPC1
|
IC50 |
|
Antiproliferative activity against human ASPC1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human ASPC1 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36097406]
|
|
ASPC1
|
IC50 |
|
Antiproliferative activity against human Aspc-1 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human Aspc-1 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31546197]
|
|
ASPC1
|
IC50 |
3.2 μM
Compound: Vorinostat
|
Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
ASPC1
|
IC50 |
3.66 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human AsPC1 cells after 48 hrs by SRB assay
Antiproliferative activity against human AsPC1 cells after 48 hrs by SRB assay
|
[PMID: 24185378]
|
|
ASPC1
|
IC50 |
> 411 nM
Compound: Vorinostat
|
Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human ASPC1 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
B16
|
IC50 |
2.26 μM
Compound: I-1; SAHA
|
Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay
Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay
|
[PMID: 35245830]
|
|
B16
|
IC50 |
4.44 μM
Compound: 1, SAHA
|
Cytotoxicity against mouse B16 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against mouse B16 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26122774]
|
|
B16-F10
|
IC50 |
|
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
|
[PMID: 35043615]
|
|
B16-F10
|
IC50 |
|
Cytotoxicity against mouse B16F10 cells assessed as growth inhibition after 72 hrs by MTS assay
Cytotoxicity against mouse B16F10 cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 28131715]
|
|
B16-F10
|
IC50 |
|
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35152694]
|
|
B16-F10
|
IC50 |
|
Cytotoxicity against human B16-F10 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human B16-F10 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
BE(2)-C
|
IC50 |
|
Antiproliferative activity against human BE(2)-C cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human BE(2)-C cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25238284]
|
|
BE(2)-C
|
IC50 |
2 μM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human BE(2)-C cells after 72 hrs by Alamar blue assay
Antiproliferative activity against human BE(2)-C cells after 72 hrs by Alamar blue assay
|
[PMID: 22932316]
|
|
BE(2)-C
|
IC50 |
|
Antiproliferative activity against human BE2C cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human BE2C cells incubated for 48 hrs by MTT assay
|
[PMID: 37563016]
|
|
BEAS-2B
|
IC50 |
> 50 μM
Compound: 1; SAHA
|
Cytotoxicity against human BEAS2B cells assessed as reduction in cell viability after 48 hrs by SRB assay
Cytotoxicity against human BEAS2B cells assessed as reduction in cell viability after 48 hrs by SRB assay
|
[PMID: 32180916]
|
|
BGC-823
|
GI50 |
3.09 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human BGC823 cells by MTT assay
Growth inhibition of human BGC823 cells by MTT assay
|
[PMID: 23601706]
|
|
BGC-823
|
GI50 |
4.26 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human BGC823 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human BGC823 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
BGC-823
|
IC50 |
|
Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34628244]
|
|
BGC-823
|
IC50 |
|
Antiproliferative activity against human BGC823 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human BGC823 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
BGC-823
|
IC50 |
|
Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
BJ
|
IC50 |
|
Growth inhibition of human BJ cells after 48 hrs by MTT assay
Growth inhibition of human BJ cells after 48 hrs by MTT assay
|
[PMID: 20143840]
|
|
BMDM
|
CC50 |
|
Cytotoxicity against Swiss mouse BMDM assessed as reduction in cell viability measured after 72 hrs by tryphan blue assay
Cytotoxicity against Swiss mouse BMDM assessed as reduction in cell viability measured after 72 hrs by tryphan blue assay
|
[PMID: 32392053]
|
|
BT-474
|
IC50 |
|
Cytotoxicity against human BT474 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against human BT474 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 27769671]
|
|
BT-549
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human BT549 cells after 72 hrs by MTS assay
Growth inhibition of human BT549 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
BT-549
|
IC50 |
|
Cytotoxicity against human BT-549 cells harboring wild type BRCA1 and wild type BRCA2 assessed as reduction in cell viability
Cytotoxicity against human BT-549 cells harboring wild type BRCA1 and wild type BRCA2 assessed as reduction in cell viability
|
[PMID: 36053318]
|
|
BT-549
|
IC50 |
|
Antiproliferative activity against human BT-549 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against human BT-549 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
|
[PMID: 33586434]
|
|
BT-549
|
IC50 |
|
Cytotoxicity against human BT-549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human BT-549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
BXPC-3
|
GI50 |
|
Cytotoxicity against human BxPC3 cells after 72 hrs by MTS assay
Cytotoxicity against human BxPC3 cells after 72 hrs by MTS assay
|
[PMID: 24900743]
|
|
BXPC-3
|
IC50 |
|
Antiproliferative activity against human BXPC-3 cells incubated for 48 hrs by resazurin based microplate reader analysis
Antiproliferative activity against human BXPC-3 cells incubated for 48 hrs by resazurin based microplate reader analysis
|
[PMID: 37647727]
|
|
BXPC-3
|
IC50 |
|
Antiproliferative activity against human BxPC3 cells after hrs by ATP content assay
Antiproliferative activity against human BxPC3 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
BXPC-3
|
IC50 |
|
Antiproliferative activity against human BXPC-3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human BXPC-3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36097406]
|
|
BXPC-3
|
IC50 |
|
Growth inhibition of human BxPC3 cells after 72 hrs by MTS assay
Growth inhibition of human BxPC3 cells after 72 hrs by MTS assay
|
[PMID: 20055418]
|
|
BXPC-3
|
IC50 |
|
Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay
Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay
|
[PMID: 18494463]
|
|
BXPC-3
|
IC50 |
|
Antiproliferative activity against human BxPC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human BxPC3 cells after 72 hrs by MTT assay
|
[PMID: 18642892]
|
|
BXPC-3
|
IC50 |
|
Antiproliferative activity against human BxPC3 cells by MTT assay
Antiproliferative activity against human BxPC3 cells by MTT assay
|
[PMID: 19419863]
|
|
BaF3
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against mouse BaF3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against mouse BaF3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
BaF3
|
IC50 |
|
Antiproliferative activity against mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
Bcap37
|
IC50 |
|
Cytotoxicity against human Bcap37 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human Bcap37 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
Bel-7402
|
IC50 |
|
Cytotoxicity against human Bel-7402 cells incubated for 72 hrs measured by MTT assay
Cytotoxicity against human Bel-7402 cells incubated for 72 hrs measured by MTT assay
|
[PMID: 37498552]
|
|
Bel-7402
|
IC50 |
|
Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
Bel-7402
|
IC50 |
|
Cytotoxicity against human Bel-7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human Bel-7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
Bel-7402
|
IC50 |
|
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
|
[PMID: 31120744]
|
|
Bel-7402
|
IC50 |
|
Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay
|
[PMID: 30851694]
|
|
Bel-7402
|
IC50 |
|
Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
Bel7402/5-FU
|
IC50 |
|
Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay
|
[PMID: 30851694]
|
|
C6
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against rat C6 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against rat C6 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
C6
|
IC50 |
2.97 μM
Compound: Vorinostat
|
Antiproliferative activity against rat C6 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against rat C6 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
CAKI-1
|
GI50 |
|
Antiproliferative activity against human Caki1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human Caki1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
CAKI-1
|
IC50 |
|
Antiproliferative activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
Antiproliferative activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
|
[PMID: 34111829]
|
|
CAKI-1
|
IC50 |
|
Antiproliferative activity against human CAKI-1 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human CAKI-1 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
CAL-27
|
IC50 |
0.36 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in cisplatin sensitive human CAL27 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in cisplatin sensitive human CAL27 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
CAL-27
|
IC50 |
|
Inhibition of HDAC in human Cal27 cells
Inhibition of HDAC in human Cal27 cells
|
[PMID: 31787463]
|
|
CAL-27
|
IC50 |
0.61 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in cisplatin resistant human CAL27 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in cisplatin resistant human CAL27 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
CAL-27
|
IC50 |
|
Cytotoxicity against human CAL27 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human CAL27 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31787463]
|
|
CAL-27
|
IC50 |
1.96 μM
Compound: Vorinostat
|
Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay (Rvb = 9.79 uM)
Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay (Rvb = 9.79 uM)
|
[PMID: 31762274]
|
|
CAL-27
|
IC50 |
1.98 μM
Compound: Vorinostat
|
Antiproliferative activity against human CAL27 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human CAL27 cells measured after 72 hrs by MTT assay
|
[PMID: 28581289]
|
|
CAL-27
|
IC50 |
1.98 μM
Compound: Vorinostat
|
Antiproliferative activity against human CAL-27 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human CAL-27 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 33360560]
|
|
CAL-27
|
IC50 |
1.99 μM
Compound: Vorinostat
|
Antiproliferative activity against human CAL27 cells after 72 hrs by microplate reader based MTT assay
Antiproliferative activity against human CAL27 cells after 72 hrs by microplate reader based MTT assay
|
[PMID: 31431326]
|
|
CAL-27
|
IC50 |
2.08 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against cisplatin resistant human CAL27 cells after 72 hrs by MTT assay
Cytotoxicity against cisplatin resistant human CAL27 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
CAL-27
|
IC50 |
2.64 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against cisplatin sensitive human CAL27 cells after 72 hrs by MTT assay
Cytotoxicity against cisplatin sensitive human CAL27 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
CAL-27
|
IC50 |
2.64 μM
Compound: Vorinostat
|
Cytotoxicity against human CAL27 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
Cytotoxicity against human CAL27 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay
|
[PMID: 31762274]
|
|
CAL-27
|
IC50 |
|
Cytotoxicity against human Cal27 cells
Cytotoxicity against human Cal27 cells
|
[PMID: 17691763]
|
|
CAL-27
|
IC50 |
|
Cytotoxicity against human CAL27 cells overexpressing EGFR by resazurin dye reduction assay
Cytotoxicity against human CAL27 cells overexpressing EGFR by resazurin dye reduction assay
|
[PMID: 21080629]
|
|
CAL-27
|
IC50 |
|
Antiproliferative activity against human CAL27 cells
Antiproliferative activity against human CAL27 cells
|
[PMID: 20143778]
|
|
CAL-51
|
IC50 |
|
Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against human CAL-51 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
|
[PMID: 33586434]
|
|
CAPAN-1
|
IC50 |
|
Antiproliferative activity against human Capan1 cells after 72 hrs by SRB assay
Antiproliferative activity against human Capan1 cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
CAPAN-1
|
IC50 |
|
Antiproliferative activity against human CAPAN-1 cells assessed as reduction in cell viability
Antiproliferative activity against human CAPAN-1 cells assessed as reduction in cell viability
|
[PMID: 35643262]
|
|
CAPAN-1
|
IC50 |
|
Anticancer activity against human CAPAN-1 cells
Anticancer activity against human CAPAN-1 cells
|
[PMID: 34107385]
|
|
CAPAN-1
|
IC50 |
5.4 μM
Compound: Vorinostat
|
Antiproliferative activity against human CAPAN-1 cells
Antiproliferative activity against human CAPAN-1 cells
|
[PMID: 37875056]
|
|
CAPAN-1
|
IC50 |
|
Antiproliferative activity against human Capan1 cells after hrs by ATP content assay
Antiproliferative activity against human Capan1 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
CCRF-CEM
|
CC50 |
|
Cytotoxicity against human CEM cells assessed as cell death incubated for 20 hrs measured by DNS assay
Cytotoxicity against human CEM cells assessed as cell death incubated for 20 hrs measured by DNS assay
|
[PMID: 34006099]
|
|
CCRF-CEM
|
GI50 |
|
Antiproliferative activity against human CCRF-CEM cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human CCRF-CEM cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
CCRF-CEM
|
GI50 |
0.8 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTS assay
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
CCRF-CEM
|
IC50 |
|
Inhibition of HDAC in human leukemic CEM cells
Inhibition of HDAC in human leukemic CEM cells
|
[PMID: 16420064]
|
|
CCRF-CEM
|
IC50 |
|
Inhibition of HDAC in human CEM cells
Inhibition of HDAC in human CEM cells
|
[PMID: 18247554]
|
|
CCRF-CEM
|
IC50 |
|
Cytotoxicity against human CCRF-CEM cells
Cytotoxicity against human CCRF-CEM cells
|
[PMID: 17691763]
|
|
CCRF-CEM
|
IC50 |
|
Cytotoxicity against human CCRF-CEM cells after 72 hrs by alamar-blue cell viability assay
Cytotoxicity against human CCRF-CEM cells after 72 hrs by alamar-blue cell viability assay
|
[PMID: 19301902]
|
|
CCRF-CEM
|
IC50 |
|
Cytotoxicity against vincristine resistant human CCRF-CEM cells
Cytotoxicity against vincristine resistant human CCRF-CEM cells
|
[PMID: 17691763]
|
|
CCRF-CEM
|
IC50 |
|
Inhibition of human leukemic CEM cell viability
Inhibition of human leukemic CEM cell viability
|
[PMID: 16420064]
|
|
CCRF-CEM
|
IC50 |
|
Inhibition of human CEM cells assessed as viability
Inhibition of human CEM cells assessed as viability
|
[PMID: 18247554]
|
|
CESS
|
IC50 |
1.78 μM
Compound: SAHA; 6
|
Antiproliferative activity against human CESS cells incubated for 72 hrs by celltiter-glo luminescent assay
Antiproliferative activity against human CESS cells incubated for 72 hrs by celltiter-glo luminescent assay
|
[PMID: 39178382]
|
|
CHP-134
|
IC50 |
1.74 μM
Compound: Vorinostat
|
Antiproliferative activity against human CHP134 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
Antiproliferative activity against human CHP134 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
|
[PMID: 31391882]
|
|
CMK
|
IC50 |
|
Antiproliferative activity against human CMK cells after 72 hrs by MTT assay
Antiproliferative activity against human CMK cells after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
CMK
|
IC50 |
|
Antiproliferative activity against Ara-C resistant human CMK cells after 72 hrs by MTT assay
Antiproliferative activity against Ara-C resistant human CMK cells after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
CNE-2
|
IC50 |
|
Antiproliferative activity against human CNE-2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human CNE-2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
COLO 205
|
GI50 |
0.79 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
COLO 205
|
GI50 |
4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
Growth inhibition of human COLO205 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
COLO 205
|
IC50 |
|
Cytotoxicity against human COLO205 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human COLO205 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
COLO 205
|
IC50 |
2.12 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter 96 assay
Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter 96 assay
|
[PMID: 21634430]
|
|
COLO 205
|
IC50 |
|
Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation
Inhibition of HDAC1 in human COLO205 cells assessed as induction of histone H3 acetylation
|
[PMID: 20451378]
|
|
COLO 205
|
IC50 |
|
Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter assay
Antiproliferative activity against human COLO205 cells after 96 hrs by celltiter assay
|
[PMID: 19181524]
|
|
COR-L23
|
GI50 |
1100 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human COR-L23 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human COR-L23 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
COR-L23
|
GI50 |
3300 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against doxorubicin-resistant human COR-L23 cells after 72 hrs by WST-1 assay
Antiproliferative activity against doxorubicin-resistant human COR-L23 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
CT26
|
GI50 |
2.35 μM
Compound: 3; SAHA
|
Antiproliferative activity against mouse CT26 cells after 72 hrs by CCK-8 assay
Antiproliferative activity against mouse CT26 cells after 72 hrs by CCK-8 assay
|
[PMID: 35390714]
|
|
CT26
|
GI50 |
|
Antiproliferative activity against mouse CT26 cells measured after 72 hrs by CCK8 assay
Antiproliferative activity against mouse CT26 cells measured after 72 hrs by CCK8 assay
|
[PMID: 34783558]
|
|
CT26
|
IC50 |
5.65 μM
Compound: I-1; SAHA
|
Antiproliferative activity against mouse CT26 cells after 72 hrs by MTT assay
Antiproliferative activity against mouse CT26 cells after 72 hrs by MTT assay
|
[PMID: 35245830]
|
|
CT26
|
IC50 |
5.97 μM
Compound: 4; SAHA
|
Antiproliferative activity against mouse CT26 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against mouse CT26 cells after 48 hrs by CCK-8 assay
|
[PMID: 29670692]
|
|
Caco-2
|
IC50 |
|
Induction of HDAC-mediated histone acetylation in human Caco-2 cells at 5 uM after 6 hrs by indirect ELISA
Induction of HDAC-mediated histone acetylation in human Caco-2 cells at 5 uM after 6 hrs by indirect ELISA
|
[PMID: 20143840]
|
|
Caco-2
|
IC50 |
|
Ex vivo inhibition of human HDAC1 in human Caco-2 cells by fluorometric cellular activity assay
Ex vivo inhibition of human HDAC1 in human Caco-2 cells by fluorometric cellular activity assay
|
[PMID: 20143840]
|
|
Caco-2
|
IC50 |
|
Ex vivo inhibition of human HDAC3 in human Caco-2 cells by fluorometric cellular activity assay
Ex vivo inhibition of human HDAC3 in human Caco-2 cells by fluorometric cellular activity assay
|
[PMID: 20143840]
|
|
Caco-2
|
IC50 |
|
Ex vivo inhibition of human HDAC5 in human Caco-2 cells by fluorometric cellular activity assay
Ex vivo inhibition of human HDAC5 in human Caco-2 cells by fluorometric cellular activity assay
|
[PMID: 20143840]
|
|
Caco-2
|
IC50 |
|
Cytotoxicity against human Caco2 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human Caco2 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
Caco-2
|
IC50 |
|
Ex vivo inhibition of human HDAC7 in human Caco-2 cells by fluorometric cellular activity assay
Ex vivo inhibition of human HDAC7 in human Caco-2 cells by fluorometric cellular activity assay
|
[PMID: 20143840]
|
|
Caco-2
|
IC50 |
|
Growth inhibition of human Caco-2 cells after 48 hrs by MTT assay
Growth inhibition of human Caco-2 cells after 48 hrs by MTT assay
|
[PMID: 20143840]
|
|
Calu-3
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human Calu-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human Calu-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
Capan-2
|
IC50 |
|
Antiproliferative activity against human Capan2 cells after 96 hrs by MTT assay
Antiproliferative activity against human Capan2 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
DG-75
|
IC50 |
|
Antiproliferative activity against human DG75 cells after 72 hrs by MTT assay
Antiproliferative activity against human DG75 cells after 72 hrs by MTT assay
|
[PMID: 29150335]
|
|
DLD-1
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human DLD-1 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human DLD-1 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
DLD-1
|
IC50 |
|
Antiproliferative activity against human DLD1 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
Antiproliferative activity against human DLD1 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
|
[PMID: 32153186]
|
|
DMS-114
|
GI50 |
2.9 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human DMS114 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human DMS114 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
DOHH-2
|
IC50 |
|
Antiproliferative activity against human DOHH-2 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human DOHH-2 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
DOHH-2
|
IC50 |
|
Antiproliferative activity against human DOHH-2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human DOHH-2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
DU-145
|
EC50 |
|
Inhibition of human DU145 cells
Inhibition of human DU145 cells
|
[PMID: 18247554]
|
|
DU-145
|
EC50 |
1.6 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human DU-145 cells
Effective Concentration of compound to inhibit the growth of human DU-145 cells
|
[PMID: 15715470]
|
|
DU-145
|
EC50 |
|
Viability of human DU145 cells after 72 hrs by MTS assay
Viability of human DU145 cells after 72 hrs by MTS assay
|
[PMID: 18397827]
|
|
DU-145
|
EC50 |
|
Viability of human DU145 cells after 72 hrs by trypan blue staining
Viability of human DU145 cells after 72 hrs by trypan blue staining
|
[PMID: 18397827]
|
|
DU-145
|
EC50 |
|
Cytotoxicity against human DU145 cells after 72 hrs by trypan blue exclusion assay
Cytotoxicity against human DU145 cells after 72 hrs by trypan blue exclusion assay
|
[PMID: 19093884]
|
|
DU-145
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human DU145 cells after 72 hrs by MTS assay
Growth inhibition of human DU145 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
DU-145
|
GI50 |
1.36 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
DU-145
|
GI50 |
1050 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human DU145 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human DU145 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
DU-145
|
GI50 |
|
Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay
|
[PMID: 26331334]
|
|
DU-145
|
GI50 |
6.86 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human DU145 cells by MTT assay
Growth inhibition of human DU145 cells by MTT assay
|
[PMID: 23601706]
|
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability
Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability
|
[PMID: 35643262]
|
|
DU-145
|
IC50 |
0.64 μM
Compound: 1; SAHA
|
Antiproliferative activity against human DU-145 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human DU-145 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
DU-145
|
IC50 |
0.68 μM
Compound: Vorinostat
|
Cytotoxicity against human DU-145 cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
Cytotoxicity against human DU-145 cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
|
[PMID: 37875056]
|
|
DU-145
|
IC50 |
0.79 μM
Compound: 1; SAHA
|
Antiproliferative activity against human DU-145 cells incubated for 48 hrs by Sulforhodamine B staining method
Antiproliferative activity against human DU-145 cells incubated for 48 hrs by Sulforhodamine B staining method
|
[PMID: 33077264]
|
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 cells after 72 hrs by SRB assay
Antiproliferative activity against human DU145 cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
Antiproliferative activity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
|
[PMID: 25993269]
|
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Antiproliferative activity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 33965842]
|
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay
Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
|
[PMID: 22260166]
|
|
DU-145
|
IC50 |
2.12 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
Cytotoxicity against human DU145 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
|
[PMID: 23622981]
|
|
DU-145
|
IC50 |
|
Cytotoxicity against androgen-independent human DU145 cells assessed as growth inhibition after 72 hrs by MTS assay
Cytotoxicity against androgen-independent human DU145 cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 24304348]
|
|
DU-145
|
IC50 |
|
Cytotoxicity against human DU145 cells
Cytotoxicity against human DU145 cells
|
[PMID: 25240614]
|
|
DU-145
|
IC50 |
2.58 μM
Compound: Vorinostat
|
Cytotoxicity against human DU145 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
Cytotoxicity against human DU145 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
|
[PMID: 23829483]
|
|
DU-145
|
IC50 |
|
Antiproliferative activity against human DU-145 cells assessed as inhibition of cell growth incubated for 3 to 5 days by CCK-8 assay
Antiproliferative activity against human DU-145 cells assessed as inhibition of cell growth incubated for 3 to 5 days by CCK-8 assay
|
[PMID: 38367494]
|
|
DU-145
|
IC50 |
27.2 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23707260]
|
|
DU-145
|
IC50 |
|
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 28057407]
|
|
DU-145
|
IC50 |
3.7 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against ERalpha-deficient human DU145 cells expressing ERbeta assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against ERalpha-deficient human DU145 cells expressing ERbeta assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23786452]
|
|
Daudi
|
IC50 |
0.493 μM
Compound: Vorinostat
|
Cytotoxicity against human Daudi cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against human Daudi cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
EA.hy 926
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human EA.hy 926 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human EA.hy 926 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
EB-3
|
GI50 |
|
Cytotoxic activity against human EB3 cells after 3 days by MTT assay
Cytotoxic activity against human EB3 cells after 3 days by MTT assay
|
[PMID: 25380299]
|
|
EB-3
|
GI50 |
2.8 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human EB3 cells assessed as growth inhibition incubated for 3 days by MTT assay
Antiproliferative activity against human EB3 cells assessed as growth inhibition incubated for 3 days by MTT assay
|
10.1039/C4MD00252K
|
|
EBC-1
|
IC50 |
|
Antiproliferative activity against human EBC1 cells after 72 hrs by SRB assay
Antiproliferative activity against human EBC1 cells after 72 hrs by SRB assay
|
[PMID: 28835797]
|
|
EJ
|
IC50 |
5.46 μM
Compound: Vorinostat
|
Cytotoxicity against human EJ cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human EJ cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
EKVX
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human EKVX cells after 72 hrs by MTS assay
Growth inhibition of human EKVX cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
EL4
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against mouse EL4 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against mouse EL4 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
EL4
|
IC50 |
|
Antiproliferative activity against mouse EL4 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against mouse EL4 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
EOL1
|
IC50 |
|
Cytotoxicity against human EOL1cells
Cytotoxicity against human EOL1cells
|
[PMID: 17691763]
|
|
EOL1
|
IC50 |
|
Cytotoxicity against human EOL-1 cells after 72 hrs by alamar-blue cell viability assay
Cytotoxicity against human EOL-1 cells after 72 hrs by alamar-blue cell viability assay
|
[PMID: 19301902]
|
|
ES-2
|
IC50 |
|
Antiproliferative activity against human ES2 cells assessed as reduction in cell viability measured after 7 days
Antiproliferative activity against human ES2 cells assessed as reduction in cell viability measured after 7 days
|
[PMID: 35643262]
|
|
ES-2
|
IC50 |
|
Antiproliferative activity against human ES2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human ES2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
Epithelial cell
|
IC50 |
|
Cytotoxicity against nontransformed human microvascular epithelial cells
Cytotoxicity against nontransformed human microvascular epithelial cells
|
[PMID: 18494463]
|
|
Epithelial cell
|
IC50 |
14000 nM
Compound: 1, vorinostat
|
Antiproliferative activity against human renal epithelial cells by CellTiter-Blue cell viability assay
Antiproliferative activity against human renal epithelial cells by CellTiter-Blue cell viability assay
|
[PMID: 18370373]
|
|
Erythrocyte
|
IC50 |
> 2.2 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against erythrocytes (unknown origin)
Cytotoxicity against erythrocytes (unknown origin)
|
[PMID: 24904967]
|
|
Erythroleukemia cell line
|
IC50 |
|
Anticancer activity against mouse Erythroleukemia cell line assessed as inhibition of cell growth
Anticancer activity against mouse Erythroleukemia cell line assessed as inhibition of cell growth
|
[PMID: 34591474]
|
|
FHC
|
IC50 |
2.59 μM
Compound: Vorinostat
|
Cytotoxicity against human FHC cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human FHC cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33493830]
|
|
FaDu
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human FaDu cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human FaDu cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
FaDu
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human FaDu cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human FaDu cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
FaDu
|
IC50 |
5.42 μM
Compound: XII; SAHA
|
Antiproliferative activity against human FaDu cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human FaDu cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
Fibroblast
|
EC50 |
|
Cytotoxicity against human primary lung fibroblasts after 72 hrs by trypan blue exclusion assay
Cytotoxicity against human primary lung fibroblasts after 72 hrs by trypan blue exclusion assay
|
[PMID: 19093884]
|
|
Fibroblast
|
IC50 |
|
Toxicity in neonatal foreskin fibroblasts
Toxicity in neonatal foreskin fibroblasts
|
[PMID: 18212103]
|
|
Friend leukemia cell line
|
IC50 |
|
Antiproliferative activity against mouse Friend leukemia cell line assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against mouse Friend leukemia cell line assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
Friend leukemia cell line
|
IC50 |
0.99 μM
Compound: 1 (SAHA)
|
Inhibitory concentration against friend cells proliferation
Inhibitory concentration against friend cells proliferation
|
[PMID: 14613312]
|
|
Friend leukemia cell line
|
IC50 |
|
Tested in vivo for the inhibition of proliferation of friend leukemic cells
Tested in vivo for the inhibition of proliferation of friend leukemic cells
|
[PMID: 12109913]
|
|
G-401
|
CC50 |
|
Antiproliferative activity against human G401 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human G401 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19441846]
|
|
G-401
|
IC50 |
1000 nM
Compound: 1, vorinostat
|
Antiproliferative activity against human G401 cells by CellTiter-Blue cell viability assay
Antiproliferative activity against human G401 cells by CellTiter-Blue cell viability assay
|
[PMID: 18370373]
|
|
G55T2
|
IC50 |
0.78 μM
Compound: Vorinostat
|
Antiproliferative activity against human G55T2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
Antiproliferative activity against human G55T2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
|
[PMID: 31391882]
|
|
GES1
|
IC50 |
|
Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 48 hrs in presence of fedratinib by MTT assay
Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 48 hrs in presence of fedratinib by MTT assay
|
[PMID: 37796543]
|
|
GES1
|
IC50 |
|
Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34628244]
|
|
GES1
|
IC50 |
|
Antiproliferative activity against human GES-1 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human GES-1 cells incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
GES1
|
IC50 |
|
Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37796543]
|
|
GES1
|
IC50 |
|
Cytotoxicity against human GES1 cells harboring low LSD1 expression assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
Cytotoxicity against human GES1 cells harboring low LSD1 expression assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
|
[PMID: 37086699]
|
|
HAL-01
|
IC50 |
0.299 μM
Compound: Vorinostat
|
Cytotoxicity against human HAL-01 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
Cytotoxicity against human HAL-01 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
|
[PMID: 36351184]
|
|
HAL-01
|
IC50 |
0.3 μM
Compound: Vorinostat
|
Cytotoxicity against human HAL-01 cells measured for 72 hrs by celltiter-glo assay
Cytotoxicity against human HAL-01 cells measured for 72 hrs by celltiter-glo assay
|
[PMID: 38714044]
|
|
HCC 2998
|
GI50 |
|
Antiproliferative activity against human HCC2998 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human HCC2998 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
HCC1937
|
IC50 |
|
Antiproliferative activity against human HCC1937 cells assessed as reduction in cell viability
Antiproliferative activity against human HCC1937 cells assessed as reduction in cell viability
|
[PMID: 35643262]
|
|
HCC1937
|
IC50 |
|
Antiproliferative activity against human HCC1937 cells after 3 days by MTT assay
Antiproliferative activity against human HCC1937 cells after 3 days by MTT assay
|
[PMID: 28601509]
|
|
HCC827
|
IC50 |
|
Antiproliferative activity against human HCC827 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCC827 cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
HCC827
|
IC50 |
|
Antiproliferative activity against human HCC827 cells after hrs by ATP content assay
Antiproliferative activity against human HCC827 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
HCCLM3
|
IC50 |
6.52 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HCCLM3 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCCLM3 cells after 48 hrs by MTT assay
|
[PMID: 30455152]
|
|
HCT-116
|
CC50 |
|
Antiproliferative activity against human P53 expressing HCT116 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human P53 expressing HCT116 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19441846]
|
|
HCT-116
|
EC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 23820574]
|
|
HCT-116
|
EC50 |
|
Inhibition of human HCT116 cells
Inhibition of human HCT116 cells
|
[PMID: 18247554]
|
|
HCT-116
|
EC50 |
0.58 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human HCT116 cells
Effective Concentration of compound to inhibit the growth of human HCT116 cells
|
[PMID: 15715470]
|
|
HCT-116
|
EC50 |
|
Cytotoxicity against human HCT116 cells
Cytotoxicity against human HCT116 cells
|
[PMID: 18954984]
|
|
HCT-116
|
EC50 |
|
Cytotoxicity against human HCT116 cells after 71 hrs by MTS assay
Cytotoxicity against human HCT116 cells after 71 hrs by MTS assay
|
[PMID: 20392638]
|
|
HCT-116
|
EC50 |
3 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT116 cells measured after 72 hrs by WST1 assay
Antiproliferative activity against human HCT116 cells measured after 72 hrs by WST1 assay
|
[PMID: 27597246]
|
|
HCT-116
|
GI50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by SRB assay
Antiproliferative activity against human HCT116 cells after 48 hrs by SRB assay
|
[PMID: 27344487]
|
|
HCT-116
|
GI50 |
0.15 μM
Compound: SAHA; 1
|
Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 29567459]
|
|
HCT-116
|
GI50 |
0.37 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay
Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
HCT-116
|
GI50 |
0.4 μM
Compound: 2, SAHA, Vorinostat
|
Cytotoxicity against human HCT116 cells after 96 hrs by MTS-PMS assay
Cytotoxicity against human HCT116 cells after 96 hrs by MTS-PMS assay
|
[PMID: 24164245]
|
|
HCT-116
|
GI50 |
0.4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human HCT116 cells after 72 hrs by MTS assay
Growth inhibition of human HCT116 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
HCT-116
|
GI50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by Sulforhodamine B assay
|
[PMID: 31924504]
|
|
HCT-116
|
GI50 |
0.55 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
|
[PMID: 31655430]
|
|
HCT-116
|
GI50 |
0.58 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 20605448]
|
|
HCT-116
|
GI50 |
|
Growth inhibition of human HCT116 cells after 5 days by alamar blue assay
Growth inhibition of human HCT116 cells after 5 days by alamar blue assay
|
[PMID: 21978679]
|
|
HCT-116
|
GI50 |
0.65 μM
Compound: Vorinostat
|
Growth inhibition of human HCT116 cells after 72 hrs by CellTiter Glo assay
Growth inhibition of human HCT116 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 25182565]
|
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells after 48 hrs by Sulforhodamine B assay
Cytotoxicity against human HCT116 cells after 48 hrs by Sulforhodamine B assay
|
[PMID: 23639537]
|
|
HCT-116
|
GI50 |
0.94 μM
Compound: 1, SAHA
|
Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24119555]
|
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells by MTT assay
Cytotoxicity against human HCT116 cells by MTT assay
|
[PMID: 23538115]
|
|
HCT-116
|
GI50 |
|
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 48 hrs by SRB assay
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 25800646]
|
|
HCT-116
|
GI50 |
2.03 μM
Compound: 1, SAHA
|
Growth inhibition of human HCT116 cells after 96 hrs by MTT assay
Growth inhibition of human HCT116 cells after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
HCT-116
|
GI50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
|
[PMID: 24900743]
|
|
HCT-116
|
GI50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 19822426]
|
|
HCT-116
|
GI50 |
|
Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26555243]
|
|
HCT-116
|
GI50 |
740 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human HCT116 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human HCT116 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
HCT-116
|
GI50 |
|
Growth inhibition of human HCT116 cells after 72 hrs by SRB assay
Growth inhibition of human HCT116 cells after 72 hrs by SRB assay
|
[PMID: 20884208]
|
|
HCT-116
|
GI50 |
> 410 nM
Compound: Vorinostat
|
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
HCT-116
|
IC50 |
0.08 mM
Compound: Vorinostat
|
Antiproliferative activity against human HCT116 cells after 2 days by MTT assay
Antiproliferative activity against human HCT116 cells after 2 days by MTT assay
|
[PMID: 19608304]
|
|
HCT-116
|
IC50 |
0.15 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
|
[PMID: 35238576]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs
Antiproliferative activity against human HCT116 cells after 72 hrs
|
[PMID: 19084294]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs
|
[PMID: 24742384]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity human HCT116 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
Antiproliferative activity human HCT116 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
|
[PMID: 26890116]
|
|
HCT-116
|
IC50 |
0.33 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
HCT-116
|
IC50 |
0.34 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 21733698]
|
|
HCT-116
|
IC50 |
0.49 μM
Compound: 3; SAHA
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36449947]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
|
[PMID: 32738414]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 5 days by Alamar blue assay
Antiproliferative activity against human HCT116 cells after 5 days by Alamar blue assay
|
[PMID: 21420859]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
|
[PMID: 22877635]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
Antiproliferative activity against human HCT116 cells after 5 days by Alamar Blue assay
|
[PMID: 25746815]
|
|
HCT-116
|
IC50 |
0.61 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human HCT116 cells by MTT assay
Cytotoxicity against human HCT116 cells by MTT assay
|
[PMID: 24766560]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
HCT-116
|
IC50 |
0.68 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
0.69 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT-116 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay
|
[PMID: 21745740]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 36549114]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells
Cytotoxicity against human HCT116 cells
|
[PMID: 23644210]
|
|
HCT-116
|
IC50 |
0.757 μM
Compound: vorinostat
|
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
|
[PMID: 26629860]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
|
[PMID: 30245394]
|
|
HCT-116
|
IC50 |
0.76 μM
Compound: SAHA, Vorinostat
|
Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter-Glo assay
|
[PMID: 23792316]
|
|
HCT-116
|
IC50 |
0.79 mM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 20171895]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 35272009]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 24095018]
|
|
HCT-116
|
IC50 |
0.81 μM
Compound: 1, SAHA, Zolinza
|
Antiproliferative activity against human HCT116 cells
Antiproliferative activity against human HCT116 cells
|
[PMID: 21742496]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 29100734]
|
|
HCT-116
|
IC50 |
0.89 μM
Compound: 4; SAHA
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability
|
[PMID: 34314844]
|
|
HCT-116
|
IC50 |
|
Inhibition of human HCT116 cells
Inhibition of human HCT116 cells
|
[PMID: 18247554]
|
|
HCT-116
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
HCT-116
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human wild type HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human wild type HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 29100734]
|
|
HCT-116
|
IC50 |
1 μM
Compound: Vorinostat
|
Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay
Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay
|
[PMID: 30660827]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
HCT-116
|
IC50 |
1.03 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT-116 cells
Antiproliferative activity against human HCT-116 cells
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
HCT-116
|
IC50 |
1.18 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT116 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HCT116 cells after 72 hrs by CCK8 assay
|
[PMID: 30045621]
|
|
HCT-116
|
IC50 |
|
Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
|
[PMID: 36244186]
|
|
HCT-116
|
IC50 |
|
Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
|
[PMID: 21073160]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 24 hrs by sulforhodamine B assay
Cytotoxicity against human HCT116 cells after 24 hrs by sulforhodamine B assay
|
[PMID: 19359173]
|
|
HCT-116
|
IC50 |
|
Growth inhibition of human HCT116 cells after 72 hrs
Growth inhibition of human HCT116 cells after 72 hrs
|
[PMID: 26376355]
|
|
HCT-116
|
IC50 |
1.2 μM
Compound: SAHA, vorinostat
|
Growth inhibition of human HCT116 cells by SRB assay
Growth inhibition of human HCT116 cells by SRB assay
|
[PMID: 17892933]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
|
[PMID: 31991336]
|
|
HCT-116
|
IC50 |
1.27 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36153841]
|
|
HCT-116
|
IC50 |
1.28 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
|
[PMID: 25874326]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
Antiproliferative activity against human HCT116 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
|
[PMID: 28213282]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
|
[PMID: 35984756]
|
|
HCT-116
|
IC50 |
1.39 μM
Compound: Vorinostat
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
|
[PMID: 23829483]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 28057407]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
|
[PMID: 28835797]
|
|
HCT-116
|
IC50 |
1.41 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT-116 cells by MTT assay
Antiproliferative activity against human HCT-116 cells by MTT assay
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells
Antiproliferative activity against human HCT116 cells
|
[PMID: 20451378]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells measured after 72 hrs
Antiproliferative activity against human HCT-116 cells measured after 72 hrs
|
[PMID: 35697181]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells incubated for 48 hrs by MTT assay
|
[PMID: 37563016]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells measured after 48 hrs by MTT assay
|
[PMID: 35041998]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells after 48 hrs by CCK-8 assay
|
[PMID: 35939996]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as cell viability after 96 hrs by MTS reduction assay
Cytotoxicity against human HCT116 cells assessed as cell viability after 96 hrs by MTS reduction assay
|
[PMID: 18348516]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human HCT116 cells assessed as cell viability after 72 hrs by CCK8 assay
|
[PMID: 26211462]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
|
[PMID: 31413795]
|
|
HCT-116
|
IC50 |
1.85 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 27541357]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 28953386]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells
Antiproliferative activity against human HCT116 cells
|
[PMID: 29945795]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
|
[PMID: 33957387]
|
|
HCT-116
|
IC50 |
|
Concentration required to inhibit the HCT116 cell growth by 50%.
Concentration required to inhibit the HCT116 cell growth by 50%.
|
[PMID: 11831887]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 96 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
HCT-116
|
IC50 |
1.93 μM
Compound: 3, SAHA
|
Antiproliferative activity against HCT116 cells
Antiproliferative activity against HCT116 cells
|
[PMID: 16904890]
|
|
HCT-116
|
IC50 |
1000 nM
Compound: 1, SAHA
|
Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue viability assay
Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue viability assay
|
[PMID: 18809328]
|
|
HCT-116
|
IC50 |
1000 nM
Compound: 1, SAHA
|
Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human HCT116 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19410459]
|
|
HCT-116
|
IC50 |
1000 nM
Compound: 1, vorinostat
|
Antiproliferative activity against human HCT116 cells by CellTiter-Blue cell viability assay
Antiproliferative activity against human HCT116 cells by CellTiter-Blue cell viability assay
|
[PMID: 18370373]
|
|
HCT-116
|
IC50 |
11.8 nM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs in presence of SN-38 by SRB assay
|
[PMID: 32679451]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 24 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 24 hrs by MTT assay
|
[PMID: 27186676]
|
|
HCT-116
|
IC50 |
1488.6 nM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT116 cells measured after 48 hrs by sulforhodamine-B assay
Antiproliferative activity against human HCT116 cells measured after 48 hrs by sulforhodamine-B assay
|
[PMID: 27886544]
|
|
HCT-116
|
IC50 |
1617.76 nM
Compound: SAHA
|
Cytotoxicity against human HCT-116 cells after 72 hrs by SRB assay
Cytotoxicity against human HCT-116 cells after 72 hrs by SRB assay
|
[PMID: 30819618]
|
|
HCT-116
|
IC50 |
1930 nM
Compound: SAHA (1)
|
Inhibitory activity against HCT116 human colon cell growth
Inhibitory activity against HCT116 human colon cell growth
|
[PMID: 14521422]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 30243158]
|
|
HCT-116
|
IC50 |
|
Anti-proliferative activity against human HCT116 cells after 48 hrs by MTT assay
Anti-proliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 28947154]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
|
[PMID: 35043615]
|
|
HCT-116
|
IC50 |
2.43 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
2.5 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT-116 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells measured after 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
|
Inhibition of HCT116 cell proliferation (mean of two experiments)
Inhibition of HCT116 cell proliferation (mean of two experiments)
|
[PMID: 17095213]
|
|
HCT-116
|
IC50 |
|
Inhibition of HCT116 cell proliferation (mean of two experiments)
Inhibition of HCT116 cell proliferation (mean of two experiments)
|
[PMID: 17107790]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34043359]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36242988]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 24296013]
|
|
HCT-116
|
IC50 |
2.81 μM
Compound: SA, SAHA
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
HCT-116
|
IC50 |
2.85 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human HCT116 cells after 96 hrs by celltiter 96 assay
Antiproliferative activity against human HCT116 cells after 96 hrs by celltiter 96 assay
|
[PMID: 21634430]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
|
[PMID: 37086699]
|
|
HCT-116
|
IC50 |
3.07 μM
Compound: 4; SAHA
|
Antiproliferative activity against human HCT116 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HCT116 cells after 48 hrs by CCK-8 assay
|
[PMID: 29670692]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity in human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity in human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 28885834]
|
|
HCT-116
|
IC50 |
3.13 μM
Compound: Vorinostat
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37875056]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by WST8 assay
Antiproliferative activity against human HCT116 cells after 72 hrs by WST8 assay
|
[PMID: 25261927]
|
|
HCT-116
|
IC50 |
3.59 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
|
[PMID: 34656899]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25815139]
|
|
HCT-116
|
IC50 |
|
Phototoxicity in human HCT-116 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
Phototoxicity in human HCT-116 cells assessed as reduction in cell viability irradiated 10 j/cm2 for 24 hrs followed by incubated for 24 hrs by CCK8 assay
|
[PMID: 33744687]
|
|
HCT-116
|
IC50 |
|
Dark toxicity in human HCT-116 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
Dark toxicity in human HCT-116 cells assessed as reduction in cell viability incubated under dark for 48 hrs measured after 48 hrs by CCK8 assay
|
[PMID: 33744687]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 33668008]
|
|
HCT-116
|
IC50 |
4.2 μM
Compound: Vorinostat
|
Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
|
[PMID: 37989057]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
HCT-116
|
IC50 |
4.25 μM
Compound: 1, SAHA
|
Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26122774]
|
|
HCT-116
|
IC50 |
4.25 μM
Compound: 6, SAHA
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 25906087]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 32151834]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells by MTT assay
Antiproliferative activity against human HCT116 cells by MTT assay
|
[PMID: 31546197]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells incubated for 48 hrs by MTT assay
|
[PMID: 30851694]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
|
[PMID: 29100734]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26555243]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 29288941]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 30108831]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37116762]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
|
[PMID: 30115492]
|
|
HCT-116
|
IC50 |
|
Inhibition of human HCT116 cell proliferation after 48 hrs by MTT assay
Inhibition of human HCT116 cell proliferation after 48 hrs by MTT assay
|
[PMID: 23493449]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 26349626]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as growth inhibition
Antiproliferative activity against human HCT116 cells assessed as growth inhibition
|
[PMID: 21650221]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 30629434]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
|
[PMID: 32679451]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 29348808]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 29954683]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
|
[PMID: 32153186]
|
|
HCT-116
|
IC50 |
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
HCT-116
|
IC50 |
|
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
HCT-15
|
GI50 |
0.82 μM
Compound: 1, SAHA
|
Growth inhibition of HCT15 cells by SRB assay
Growth inhibition of HCT15 cells by SRB assay
|
[PMID: 17477518]
|
|
HCT-15
|
GI50 |
0.82 μM
Compound: 2, SAHA
|
Antiproliferative activity against human HCT15 cells by SRB assay
Antiproliferative activity against human HCT15 cells by SRB assay
|
[PMID: 16723227]
|
|
HCT-15
|
GI50 |
|
Growth inhibition of human HCT15 cells after 21 hrs by MTT assay
Growth inhibition of human HCT15 cells after 21 hrs by MTT assay
|
[PMID: 17662606]
|
|
HCT-15
|
GI50 |
2.49 μM
Compound: 1, SAHA
|
Growth inhibition of human HCT15 cells
Growth inhibition of human HCT15 cells
|
[PMID: 20850971]
|
|
HCT-15
|
GI50 |
2.49 μM
Compound: 1, SAHA, Zolinza, Vorinostat
|
Cytotoxicity against human HCT15 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human HCT15 cells assessed as growth inhibition by SRB assay
|
[PMID: 23163332]
|
|
HCT-15
|
GI50 |
2.49 μM
Compound: 2, SAHA
|
Growth inhibition of human HCT15 cells by SRB assay
Growth inhibition of human HCT15 cells by SRB assay
|
[PMID: 17904843]
|
|
HCT-15
|
GI50 |
|
Growth inhibition of human HCT15 cells after 5 days by sulforhodamine B assay
Growth inhibition of human HCT15 cells after 5 days by sulforhodamine B assay
|
[PMID: 25811792]
|
|
HCT-15
|
GI50 |
|
Growth inhibition of human HCT15 cells measured after 5 days by sulforhodamine-B assay
Growth inhibition of human HCT15 cells measured after 5 days by sulforhodamine-B assay
|
[PMID: 28011426]
|
|
HCT-15
|
GI50 |
2.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human HCT15 cells after 72 hrs by MTS assay
Growth inhibition of human HCT15 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
HCT-15
|
IC50 |
|
Cytotoxicity against human HCT15 cells
Cytotoxicity against human HCT15 cells
|
[PMID: 17691763]
|
|
HCT-8
|
IC50 |
0.35 μM
Compound: 5; SAHA
|
Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay
Antiproliferative activity against human HCT8 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
HEC-1-A
|
IC50 |
|
Cytotoxicity against human Hec-1-A cells
Cytotoxicity against human Hec-1-A cells
|
[PMID: 17691763]
|
|
HEK-293T
|
EC50 |
|
Cytotoxicity against human HEK293T cells assessed as cell growth inhibition
Cytotoxicity against human HEK293T cells assessed as cell growth inhibition
|
[PMID: 33356214]
|
|
HEK-293T
|
IC50 |
4.5 μM
Compound: Vorinostat
|
Cytotoxicity against HEK293T cells incubated for 72 hrs by CCK-8 assay
Cytotoxicity against HEK293T cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 35175762]
|
|
HEK-293T
|
IC50 |
|
Cytotoxicity against human HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
HEK293
|
CC50 |
100 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against HEK293 cells assessed as reduction in cell viability
Cytotoxicity against HEK293 cells assessed as reduction in cell viability
|
[PMID: 26264503]
|
|
HEK293
|
CC50 |
2.3 μM
Compound: Vorinostat
|
Cytotoxicity against HEK293 cells assessed as reduction in cell growth incubated for 48 hrs by MTS assay
Cytotoxicity against HEK293 cells assessed as reduction in cell growth incubated for 48 hrs by MTS assay
|
[PMID: 30973727]
|
|
HEK293
|
GI50 |
|
Growth inhibition of human HEK293 cells after 72 hrs by XTT assay
Growth inhibition of human HEK293 cells after 72 hrs by XTT assay
|
[PMID: 24900500]
|
|
HEK293
|
GI50 |
3.38 μM
Compound: 1, SAHA
|
Cytotoxicity against HEK293 cells assessed as growth inhibition after 96 hrs by MTT assay
Cytotoxicity against HEK293 cells assessed as growth inhibition after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
HEK293
|
IC50 |
|
Inhibition of recombinant human GST-fused HDAC1 expressed in HEK293 cells Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
Inhibition of recombinant human GST-fused HDAC1 expressed in HEK293 cells Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
|
[PMID: 30245394]
|
|
HEK293
|
IC50 |
0.013 μM
Compound: 2, SAHA
|
Inhibition of human recombinant HDAC1 expressed in human HEK293 cells using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
Inhibition of human recombinant HDAC1 expressed in human HEK293 cells using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
|
10.1039/C2MD00317A
|
|
HEK293
|
IC50 |
|
Inhibition of full length human N-terminal FLAG-tagged HDAC6 (1 to 1215 residues) expressed in HEK293 cells preincubated for 15 mins followed by acetyl-Gly-Ala-[acetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
Inhibition of full length human N-terminal FLAG-tagged HDAC6 (1 to 1215 residues) expressed in HEK293 cells preincubated for 15 mins followed by acetyl-Gly-Ala-[acetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
|
[PMID: 30613344]
|
|
HEK293
|
IC50 |
|
Inhibition of recombinant HDAC6 expressed in HEK293 cells
Inhibition of recombinant HDAC6 expressed in HEK293 cells
|
[PMID: 18558669]
|
|
HEK293
|
IC50 |
0.02 μM
Compound: 6, SAHA
|
Inhibition of human recombinant HDAC1 expressed in HEK293 cells
Inhibition of human recombinant HDAC1 expressed in HEK293 cells
|
[PMID: 19301902]
|
|
HEK293
|
IC50 |
|
Inhibition of human recombinant HDAC1 expressed in HEK293 cells
Inhibition of human recombinant HDAC1 expressed in HEK293 cells
|
[PMID: 21080629]
|
|
HEK293
|
IC50 |
|
Inhibition of human recombinant HDAC6 expressed in HEK293 cells
Inhibition of human recombinant HDAC6 expressed in HEK293 cells
|
[PMID: 21080629]
|
|
HEK293
|
IC50 |
|
Inhibition of recombinant HDAC1 expressed in HEK293 cells
Inhibition of recombinant HDAC1 expressed in HEK293 cells
|
[PMID: 18558669]
|
|
HEK293
|
IC50 |
0.052 μM
Compound: 6, SAHA
|
Inhibition of human recombinant HDAC6 expressed in HEK293 cells
Inhibition of human recombinant HDAC6 expressed in HEK293 cells
|
[PMID: 19301902]
|
|
HEK293
|
IC50 |
|
Inhibition of HDAC1 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
Inhibition of HDAC1 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
|
[PMID: 31414801]
|
|
HEK293
|
IC50 |
|
Inhibition of HDAC6 CD2 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
Inhibition of HDAC6 CD2 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET assay
|
[PMID: 31414801]
|
|
HEK293
|
IC50 |
|
Inhibition of full length human N-terminal FLAG-tagged HDAC8 (1 to 377 residues) expressed in HEK293 cells preincubated for 15 mins followed by Boc-[trifluoroacetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
Inhibition of full length human N-terminal FLAG-tagged HDAC8 (1 to 377 residues) expressed in HEK293 cells preincubated for 15 mins followed by Boc-[trifluoroacetyl-Lys]-AMC substrate addition measured after 30 mins by fluorimetric method
|
[PMID: 30613344]
|
|
HEK293
|
IC50 |
1637 nM
Compound: 1; SAHA
|
Antiproliferative activity against human HEK293 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HEK293 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells
Cytotoxicity against HEK293 cells
|
[PMID: 34107385]
|
|
HEK293
|
IC50 |
|
Cytotoxicity HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs
Cytotoxicity HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs
|
[PMID: 38056296]
|
|
HEK293
|
IC50 |
|
Inhibition of human C-terminal FLAG-tagged HDAC1 in HEK293 cells
Inhibition of human C-terminal FLAG-tagged HDAC1 in HEK293 cells
|
[PMID: 19441846]
|
|
HEK293
|
IC50 |
30 nM
Compound: vorinostat, zolinza, SAHA
|
Inhibition of HDAC1 in HEK293 cells
Inhibition of HDAC1 in HEK293 cells
|
[PMID: 18308563]
|
|
HEK293
|
IC50 |
43 nM
Compound: vorinostat, zolinza, SAHA
|
Inhibition of HDAC6 in HEK293 cells
Inhibition of HDAC6 in HEK293 cells
|
[PMID: 18308563]
|
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells after 48 hrs by resazurin dye based assay
Cytotoxicity against HEK293 cells after 48 hrs by resazurin dye based assay
|
[PMID: 30245402]
|
|
HEK293
|
IC50 |
|
Inhibition of human C-terminal FLAG-tagged HDAC3 in HEK293 cells
Inhibition of human C-terminal FLAG-tagged HDAC3 in HEK293 cells
|
[PMID: 19441846]
|
|
HEK293
|
IC50 |
57 nM
Compound: vorinostat, zolinza, SAHA
|
Inhibition of HDAC3 in HEK293 cells
Inhibition of HDAC3 in HEK293 cells
|
[PMID: 18308563]
|
|
HEK293
|
IC50 |
|
Inhibition of human C-terminal FLAG-tagged HDAC2 in HEK293 cells
Inhibition of human C-terminal FLAG-tagged HDAC2 in HEK293 cells
|
[PMID: 19441846]
|
|
HEK293
|
IC50 |
|
Cytotoxicity against HEK293 cells incubated for 24 hrs by Neutral Red Uptake assay
Cytotoxicity against HEK293 cells incubated for 24 hrs by Neutral Red Uptake assay
|
[PMID: 39208744]
|
|
HEK293
|
IC50 |
|
Inhibition of recombinant human ERG expressed in HEK293 cells at -80 mV holding potential measured for 9 mins by Qpatch clamp method
Inhibition of recombinant human ERG expressed in HEK293 cells at -80 mV holding potential measured for 9 mins by Qpatch clamp method
|
[PMID: 28947154]
|
|
HEL
|
GI50 |
|
Antiproliferative activity against human HEL cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
Antiproliferative activity against human HEL cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
|
[PMID: 25800646]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against HEL cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against HEL cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35152694]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
|
[PMID: 29533873]
|
|
HEL
|
IC50 |
0.18 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HEL cells incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human HEL cells incubated for 48 hrs by CCK8 assay
|
[PMID: 37037787]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against HEL cells incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against HEL cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37057760]
|
|
HEL
|
IC50 |
|
Cytotoxicity against HEL cells assessed as reduction in cell growth incubated for 72 hrs by WST assay
Cytotoxicity against HEL cells assessed as reduction in cell growth incubated for 72 hrs by WST assay
|
[PMID: 38964169]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells after 72 hrs by MTT assay
Antiproliferative activity against human HEL cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
|
[PMID: 28336407]
|
|
HEL
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Antiproliferative activity against human HEL cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HEL cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
HEL
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Cytotoxicity against HEL cells assessed as reduction in cell viability incubated for 72 hrs by WST assay
Cytotoxicity against HEL cells assessed as reduction in cell viability incubated for 72 hrs by WST assay
|
[PMID: 38107170]
|
|
HEL
|
IC50 |
0.25 μM
Compound: Vorinostat
|
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
|
[PMID: 28371677]
|
|
HEL
|
IC50 |
|
Synergistic antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
Synergistic antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
|
[PMID: 30901208]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
Antiproliferative activity against human HEL cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
|
[PMID: 36622852]
|
|
HEL
|
IC50 |
0.49 μM
Compound: SA, SAHA
|
Antiproliferative activity against HEL cells after 48 hrs by MTT assay
Antiproliferative activity against HEL cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
Antiproliferative activity against human HEL cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
|
[PMID: 36622852]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
|
[PMID: 35939996]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against HEL cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
Antiproliferative activity against HEL cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
|
[PMID: 35238576]
|
|
HEL
|
IC50 |
0.65 μM
Compound: 3; SAHA
|
Antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against HEL cells harboring JAK2 V617F mutant assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30901208]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against HEL cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against HEL cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
|
[PMID: 29500131]
|
|
HEL
|
IC50 |
0.86 μM
Compound: 2; SAHA
|
Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HEL cells after 48 hrs by CCK-8 assay
|
[PMID: 29940115]
|
|
HEL
|
IC50 |
|
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
|
[PMID: 30879863]
|
|
HEL
|
IC50 |
|
Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 26349626]
|
|
HEL
|
IC50 |
1.74 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
HEL
|
IC50 |
2.42 μM
Compound: 1, SAHA
|
Cytotoxicity against HEL cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against HEL cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26122774]
|
|
HEL
|
IC50 |
2.42 μM
Compound: 6, SAHA
|
Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HEL cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 25906087]
|
|
HEL 92.1.7
|
IC50 |
0.49 μM
Compound: 1; SAHA
|
Antiproliferative activity against HEL 92.1.7 cells harboring JAK2 V617F mutant after 36 hrs by PrestoBlue dye based assay
Antiproliferative activity against HEL 92.1.7 cells harboring JAK2 V617F mutant after 36 hrs by PrestoBlue dye based assay
|
[PMID: 27541357]
|
|
HEL 92.1.7
|
IC50 |
|
Antiproliferative activity against human HEL 92.1.7 cells after 36 hrs by PrestoBlue dye based assay
Antiproliferative activity against human HEL 92.1.7 cells after 36 hrs by PrestoBlue dye based assay
|
[PMID: 28953386]
|
|
HEL 92.1.7
|
IC50 |
|
Antiproliferative activity against human HEL 92.1.7 cells after 72 hrs by MTT assay
Antiproliferative activity against human HEL 92.1.7 cells after 72 hrs by MTT assay
|
[PMID: 30243158]
|
|
HET-1A
|
IC50 |
|
Antiproliferative activity against human HET-1A cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HET-1A cells incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
HGC-27
|
IC50 |
0.35 μM
Compound: 5; SAHA
|
Antiproliferative activity against human HGC27 cells after 96 hrs by MTT assay
Antiproliferative activity against human HGC27 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
HGC-27
|
IC50 |
3 μM
Compound: Vorinostat
|
Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
HGC-27
|
IC50 |
5.4 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against human HGC27 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HGC27 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23707260]
|
|
HGC-27
|
IC50 |
|
Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34628244]
|
|
HGC-27
|
IC50 |
|
Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
HH
|
EC50 |
|
Cytotoxicity against human HH cells assessed as cell proliferation after 70 hrs by MTS assay
Cytotoxicity against human HH cells assessed as cell proliferation after 70 hrs by MTS assay
|
[PMID: 25974739]
|
|
HH
|
IC50 |
0.86 μM
Compound: 1; SAHA
|
Cytotoxicity against human HH cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human HH cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 33588178]
|
|
HH
|
IC50 |
2.53 μM
Compound: XII; SAHA
|
Antiproliferative activity against human HH cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HH cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
HL-60
|
EC50 |
1.2 μM
Compound: 1a, SAHA
|
Antiproliferative activity against human HL60 cells after 48 hrs by cell titer-glo assay
Antiproliferative activity against human HL60 cells after 48 hrs by cell titer-glo assay
|
[PMID: 20218673]
|
|
HL-60
|
EC50 |
|
Induction of ATRA-induced human HL60 cell differentiation pretreated for 1 hr followed by ATRA addition measured after 3 days by Wright-Giemsa staining based microscopic analysis
Induction of ATRA-induced human HL60 cell differentiation pretreated for 1 hr followed by ATRA addition measured after 3 days by Wright-Giemsa staining based microscopic analysis
|
[PMID: 28549889]
|
|
HL-60
|
GI50 |
|
Cytotoxicity against human HL60 cells after 72 hrs by cell titre 96 aqueous cell proliferation assay
Cytotoxicity against human HL60 cells after 72 hrs by cell titre 96 aqueous cell proliferation assay
|
[PMID: 26653328]
|
|
HL-60
|
GI50 |
|
Antiproliferative activity against human HL60 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
Antiproliferative activity against human HL60 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
|
[PMID: 25800646]
|
|
HL-60
|
GI50 |
0.75 μM
Compound: Vorinostat
|
Growth inhibition of human HL60 cells after 72 hrs by CellTiter Glo assay
Growth inhibition of human HL60 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 25182565]
|
|
HL-60
|
GI50 |
0.93 μM
Compound: 1, SAHA
|
Growth inhibition of human HL60 cells after 72 hrs by XTT assay
Growth inhibition of human HL60 cells after 72 hrs by XTT assay
|
[PMID: 24900500]
|
|
HL-60
|
GI50 |
|
Antiproliferative activity against human HL60 cells after 48 hrs by SRB assay
Antiproliferative activity against human HL60 cells after 48 hrs by SRB assay
|
[PMID: 27344487]
|
|
HL-60
|
GI50 |
1.74 μM
Compound: SAHA; 1
|
Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 29567459]
|
|
HL-60
|
IC50 |
0.18 μg/mL
Compound: Vorinostat
|
Antiproliferative activity against human HL-60 cells
Antiproliferative activity against human HL-60 cells
|
[PMID: 31945642]
|
|
HL-60
|
IC50 |
0.18 μg/mL
Compound: Vorinostat
|
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
HL-60
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
HL-60
|
IC50 |
0.22 μM
Compound: Vorinostat
|
Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
|
[PMID: 36351184]
|
|
HL-60
|
IC50 |
0.22 μM
Compound: Vorinostat
|
Cytotoxicity against human HL-60 cells measured for 72 hrs by celltiter-glo assay
Cytotoxicity against human HL-60 cells measured for 72 hrs by celltiter-glo assay
|
[PMID: 38714044]
|
|
HL-60
|
IC50 |
|
Inhibition of cell viability in human HL-60 cells incubated for 4 days in presence of GSK5032 by CCK8 assay
Inhibition of cell viability in human HL-60 cells incubated for 4 days in presence of GSK5032 by CCK8 assay
|
[PMID: 39264152]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells incubated for 48 hrs by resazurin based microplate reader analysis
Antiproliferative activity against human HL-60 cells incubated for 48 hrs by resazurin based microplate reader analysis
|
[PMID: 37647727]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition after 72 hrs by trypan blue staining based cell counting assay
Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition after 72 hrs by trypan blue staining based cell counting assay
|
[PMID: 31883490]
|
|
HL-60
|
IC50 |
0.48 μM
Compound: 1; SAHA
|
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 33588178]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HL-60 cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37057760]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells incubated for 48 hrs by MTT assay
|
[PMID: 31413795]
|
|
HL-60
|
IC50 |
0.54 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36153841]
|
|
HL-60
|
IC50 |
|
Inhibition of cell viability in human HL-60 cells incubated for 4 days by CCK8 assay
Inhibition of cell viability in human HL-60 cells incubated for 4 days by CCK8 assay
|
[PMID: 39264152]
|
|
HL-60
|
IC50 |
0.69 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HL-60 cells incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human HL-60 cells incubated for 48 hrs by CCK8 assay
|
[PMID: 37037787]
|
|
HL-60
|
IC50 |
0.69 μM
Compound: Vorinostat
|
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL-60 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
Cytotoxicity against human HL-60 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
|
[PMID: 34185525]
|
|
HL-60
|
IC50 |
0.93 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
|
[PMID: 34656899]
|
|
HL-60
|
IC50 |
|
Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
|
[PMID: 36622852]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
|
[PMID: 36622852]
|
|
HL-60
|
IC50 |
1.4 μM
Compound: Vorinostat
|
Antiproliferative activity against human HL-60 cells
Antiproliferative activity against human HL-60 cells
|
[PMID: 37875056]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HL60 cells after 48 hrs by CCK-8 assay
|
[PMID: 29940115]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
|
[PMID: 36272186]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against Ara-C resistant human HL60 cells after 72 hrs by MTT assay
Antiproliferative activity against Ara-C resistant human HL60 cells after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
HL-60
|
IC50 |
2.21 μM
Compound: 1; SAHA
|
Anticancer activity against human HL-60 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
Anticancer activity against human HL-60 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
|
[PMID: 36215854]
|
|
HL-60
|
IC50 |
2.28 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HL60 cells
Antiproliferative activity against human HL60 cells
|
[PMID: 27541357]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells
Antiproliferative activity against human HL60 cells
|
[PMID: 28953386]
|
|
HL-60
|
IC50 |
2.91 μM
Compound: XII; SAHA
|
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
HL-60
|
IC50 |
3 μM
Compound: Vorinostat
|
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
HL-60
|
IC50 |
4.26 μM
Compound: SA, SAHA
|
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
HL-60
|
IC50 |
|
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
HL-60
|
IC50 |
|
Growth inhibition of human HL60 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
Growth inhibition of human HL60 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
|
10.1039/C3MD00285C
|
|
HL-60
|
IC50 |
76.5 μM
Compound: Zolinza, SAHA
|
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 22698782]
|
|
HL-60
|
IC50 |
> 200 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 21476600]
|
|
HL-60
|
IC50 |
> 3.78 mM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 20171895]
|
|
HL-60(TB)
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human HL-60(TB) cells after 72 hrs by MTS assay
Growth inhibition of human HL-60(TB) cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
HMEC
|
EC50 |
|
Cytotoxicity against HMEC after 72 hrs by trypan blue exclusion assay
Cytotoxicity against HMEC after 72 hrs by trypan blue exclusion assay
|
[PMID: 19093884]
|
|
HMEC
|
GI50 |
5.8 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human HMEC after 72 hrs by WST1 assay
Cytotoxicity against human HMEC after 72 hrs by WST1 assay
|
[PMID: 24015327]
|
|
HMEC
|
IC50 |
|
Cytotoxicity against HMEC after 72 hrs by MTT assay
Cytotoxicity against HMEC after 72 hrs by MTT assay
|
[PMID: 18642892]
|
|
HMEC
|
IC50 |
10.7 μM
Compound: Vorinostat
|
Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
|
[PMID: 36262394]
|
|
HMEC
|
IC50 |
4.41 μM
Compound: 1; SAHA
|
Cytotoxicity against human HMEC cells assessed as inhibition of cell viability incubated for 3 days by AlamarBlue based fluorescence analysis
Cytotoxicity against human HMEC cells assessed as inhibition of cell viability incubated for 3 days by AlamarBlue based fluorescence analysis
|
[PMID: 37847303]
|
|
HOP-62
|
GI50 |
|
Antiproliferative activity against human HOP62 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human HOP62 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
HOP-62
|
IC50 |
|
Cytotoxicity against human HOP-62 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HOP-62 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 35858522]
|
|
HOP-92
|
GI50 |
|
Antiproliferative activity against human HOP92 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human HOP92 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
HOP-92
|
GI50 |
4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human HOP92 cells after 72 hrs by MTS assay
Growth inhibition of human HOP92 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
HSC-3
|
IC50 |
0.71 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human HSC3 cells by MTT assay
Cytotoxicity against human HSC3 cells by MTT assay
|
[PMID: 24766560]
|
|
HT-1080
|
GI50 |
1.79 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human HT1080 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human HT1080 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
HT-1080
|
GI50 |
4.87 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human HT1080 cells by MTT assay
Growth inhibition of human HT1080 cells by MTT assay
|
[PMID: 23601706]
|
|
HT-1080
|
IC50 |
|
Inhibition of human HT1080 cells
Inhibition of human HT1080 cells
|
[PMID: 18247554]
|
|
HT-1080
|
IC50 |
|
Concentration required for the antiproliferation of Human HT1080 fibrosarcoma cells
Concentration required for the antiproliferation of Human HT1080 fibrosarcoma cells
|
[PMID: 12270175]
|
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 fibrosarcoma cell line
Antiproliferative activity against human HT1080 fibrosarcoma cell line
|
[PMID: 14552787]
|
|
HT-1080
|
IC50 |
2.4 μM
Compound: 3 (SAHA)
|
Antiproliferative activity against HT1080 (human fibrosarcoma) cell line.
Antiproliferative activity against HT1080 (human fibrosarcoma) cell line.
|
[PMID: 12749893]
|
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
HT-1080
|
IC50 |
|
Antiproliferative activity against human HT1080 cells
Antiproliferative activity against human HT1080 cells
|
[PMID: 31655430]
|
|
HT-1080
|
IC50 |
2400 nM
Compound: 1 (SAHA)
|
Inhibitory concentration against HT1080 cells proliferation
Inhibitory concentration against HT1080 cells proliferation
|
[PMID: 14613312]
|
|
HT-1080
|
IC50 |
|
Anticancer activity against human HT-1080 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
Anticancer activity against human HT-1080 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
|
[PMID: 36244186]
|
|
HT-1080
|
IC50 |
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 23953690]
|
|
HT-29
|
EC50 |
|
Antiproliferative activity against human HT-29 cells after 48 hrs by cell titer-glo assay
Antiproliferative activity against human HT-29 cells after 48 hrs by cell titer-glo assay
|
[PMID: 20218673]
|
|
HT-29
|
GI50 |
0.79 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human HT-29 cells after 72 hrs by MTS assay
Growth inhibition of human HT-29 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
HT-29
|
GI50 |
2.88 μM
Compound: 1, SAHA
|
Growth inhibition of human HT-29 cells after 96 hrs by MTT assay
Growth inhibition of human HT-29 cells after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
HT-29
|
IC50 |
0.72 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human HT-29 cells by MTT assay
Cytotoxicity against human HT-29 cells by MTT assay
|
[PMID: 24766560]
|
|
HT-29
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
HT-29
|
IC50 |
1.78 μM
Compound: 4; SAHA
|
Antiproliferative activity against human HT-29 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HT-29 cells after 48 hrs by CCK-8 assay
|
[PMID: 29670692]
|
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 72 hrs by SRB assay
Antiproliferative activity against human HT-29 cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
HT-29
|
IC50 |
2.33 μM
Compound: 1; SAHA
|
Antiproliferative activity against human HT-29 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human HT-29 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
HT-29
|
IC50 |
|
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 30879863]
|
|
HT-29
|
IC50 |
|
Anticancer activity against human HT-29 cells assessed as inhibition of cell growth measured for 48 hrs by MTT assay
Anticancer activity against human HT-29 cells assessed as inhibition of cell growth measured for 48 hrs by MTT assay
|
[PMID: 38897139]
|
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
HT-29
|
IC50 |
5.01 μM
Compound: Vorinostat
|
Antiproliferative activity against human HT-29 cells
Antiproliferative activity against human HT-29 cells
|
[PMID: 37875056]
|
|
HT-29
|
IC50 |
|
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
HUVEC
|
GI50 |
8.13 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of HUVEC by MTT assay
Growth inhibition of HUVEC by MTT assay
|
[PMID: 23601706]
|
|
HUVEC
|
IC50 |
|
Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by fluorimetry
Inhibition of HDAC in HUVEC using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 4 hrs by fluorimetry
|
[PMID: 32347094]
|
|
HUVEC
|
IC50 |
|
Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured after 6 hrs by microtiter plate reader analysis
Inhibition of total HDAC in human HUVEC cells using Boc-Lys(Ac)-AMC as substrate preincubated for 12 hrs followed by substrate addition measured after 6 hrs by microtiter plate reader analysis
|
[PMID: 37037787]
|
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37116762]
|
|
HUVEC
|
IC50 |
|
Antiproliferative activity against human HUVEC cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HUVEC cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth
|
[PMID: 35944852]
|
|
HUVEC
|
IC50 |
|
Antiproliferative activity against HUVEC cells incubated for 48 hrs by MTT assay
Antiproliferative activity against HUVEC cells incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVECs assessed as inhibition of cell growth incubated for 48 hrs by CCK8 assay
Cytotoxicity against HUVECs assessed as inhibition of cell growth incubated for 48 hrs by CCK8 assay
|
[PMID: 37037787]
|
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC cells incubated for 72 hrs by CCK-8 assay
Cytotoxicity against HUVEC cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 36182802]
|
|
HUVEC
|
IC50 |
|
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
|
[PMID: 37079967]
|
|
HaCaT
|
IC50 |
|
Cytotoxicity against human HaCaT cells assessed as inhibition of cell growth
Cytotoxicity against human HaCaT cells assessed as inhibition of cell growth
|
[PMID: 34742014]
|
|
HeLa
|
CC50 |
|
Cytotoxicity against human HeLa cells assessed as cell death incubated for 20 hrs measured by DNS assay
Cytotoxicity against human HeLa cells assessed as cell death incubated for 20 hrs measured by DNS assay
|
[PMID: 34006099]
|
|
HeLa
|
CC50 |
|
Antiproliferative activity against human P53-deficient HeLa cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human P53-deficient HeLa cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19441846]
|
|
HeLa
|
EC50 |
0.0217 μM
Compound: 1; SAHA; vorinostat
|
Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA
Inhibition of HDAC6 in human HeLa cells assessed as inhibition of tubulin deacetylation incubated for overnight by cELISA
|
[PMID: 26611919]
|
|
HeLa
|
EC50 |
0.55 μM
Compound: 1, SAHA
|
Inhibition of histone deacetylase in human HeLa cells assessed as induction of histone H3 hyperacetylation
Inhibition of histone deacetylase in human HeLa cells assessed as induction of histone H3 hyperacetylation
|
[PMID: 18954984]
|
|
HeLa
|
EC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by XTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by XTT assay
|
[PMID: 21548582]
|
|
HeLa
|
EC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by XTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by XTT assay
|
[PMID: 21548582]
|
|
HeLa
|
EC50 |
|
Inhibition of HDAC in human HeLa cells assessed as induction of histone H3 hyperacetylation after 24 hrs
Inhibition of HDAC in human HeLa cells assessed as induction of histone H3 hyperacetylation after 24 hrs
|
[PMID: 18558669]
|
|
HeLa
|
EC50 |
|
Antiproliferative activity against human HeLa cells after 24 hrs by XTT assay
Antiproliferative activity against human HeLa cells after 24 hrs by XTT assay
|
[PMID: 21548582]
|
|
HeLa
|
EC50 |
|
Inhibition of HDAC in HeLa cells assessed as induction of human histone H3 hyperacetylation
Inhibition of HDAC in HeLa cells assessed as induction of human histone H3 hyperacetylation
|
[PMID: 17691763]
|
|
HeLa
|
EC50 |
|
Inhibition of HDAC in human HeLa cells assessed as induction of cellular histone H3 hyperacetylation
Inhibition of HDAC in human HeLa cells assessed as induction of cellular histone H3 hyperacetylation
|
[PMID: 19301902]
|
|
HeLa
|
GI50 |
|
Growth inhibition of human HeLa cells after 72 hrs by SRB assay
Growth inhibition of human HeLa cells after 72 hrs by SRB assay
|
[PMID: 20884208]
|
|
HeLa
|
GI50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 28629630]
|
|
HeLa
|
GI50 |
|
Growth inhibition of human HeLa cells after 72 hrs by XTT assay
Growth inhibition of human HeLa cells after 72 hrs by XTT assay
|
[PMID: 24900500]
|
|
HeLa
|
GI50 |
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
|
[PMID: 34500130]
|
|
HeLa
|
GI50 |
3.2 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
HeLa
|
GI50 |
3.36 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human HeLa cells by MTT assay
Growth inhibition of human HeLa cells by MTT assay
|
[PMID: 23601706]
|
|
HeLa
|
IC50 |
|
Inhibition of recombinant HDAC1 in HeLa cells
Inhibition of recombinant HDAC1 in HeLa cells
|
[PMID: 17691763]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell extract using Fluor deLys as substrate by fluorimetric assay
Inhibition of HDAC in human HeLa cell extract using Fluor deLys as substrate by fluorimetric assay
|
[PMID: 23820574]
|
|
HeLa
|
IC50 |
0.055 μM
Compound: 1, SAHA
|
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence-based assay
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence-based assay
|
[PMID: 26814680]
|
|
HeLa
|
IC50 |
0.063 μM
Compound: 2, SAHA
|
Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate preincubated for 4 hrs before substrate addition measured after 3 hrs by fluorescence assay
Inhibition of HDAC in human HeLa cells using Boc-K(Ac)-AMC as substrate preincubated for 4 hrs before substrate addition measured after 3 hrs by fluorescence assay
|
10.1039/C2MD00317A
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in HeLa cells
Inhibition of HDAC in HeLa cells
|
[PMID: 17691763]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extracts
Inhibition of HDAC in human HeLa cell nuclear extracts
|
[PMID: 21080629]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC6 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
Inhibition of HDAC6 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
|
[PMID: 26555243]
|
|
HeLa
|
IC50 |
0.079 μM
Compound: 2, SAHA
|
Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-NH-GGK(Ac)-AMC as substrate after 180 mins by fluorescence assay
|
10.1039/C2MD00317A
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cells by fluorescent activity assay
Inhibition of HDAC in human HeLa cells by fluorescent activity assay
|
[PMID: 21420859]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell extract assessed as fluorophore release by fluorescence spectrophotometry
Inhibition of HDAC in human HeLa cell extract assessed as fluorophore release by fluorescence spectrophotometry
|
[PMID: 21978679]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell extracts using Fluor de Lys as substrate by fluorescence assay
Inhibition of HDAC in human HeLa cell extracts using Fluor de Lys as substrate by fluorescence assay
|
[PMID: 22877635]
|
|
HeLa
|
IC50 |
|
Inhibition of nuclear HDAC isolated from human HeLa cells
Inhibition of nuclear HDAC isolated from human HeLa cells
|
[PMID: 18558669]
|
|
HeLa
|
IC50 |
0.09 μM
Compound: SAHA, Vorinostat
|
Inhibition of human HDAC in HeLa cells after 30 mins by Fluor de Lys fluorescence assay
Inhibition of human HDAC in HeLa cells after 30 mins by Fluor de Lys fluorescence assay
|
[PMID: 21889343]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC2 in human HeLa cells
Inhibition of HDAC2 in human HeLa cells
|
[PMID: 19084294]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cells extracts after 60 mins by fluorescence assay
Inhibition of HDAC in human HeLa cells extracts after 60 mins by fluorescence assay
|
[PMID: 20576572]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysis
Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysis
|
[PMID: 24742384]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human Hela cell nuclear extract after 15 mins
Inhibition of HDAC in human Hela cell nuclear extract after 15 mins
|
[PMID: 23644210]
|
|
HeLa
|
IC50 |
0.102 μM
Compound: vorinostat
|
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis
|
[PMID: 26629860]
|
|
HeLa
|
IC50 |
0.106 μM
Compound: Vorinostat, SAHA, Zolinza
|
Inhibition of full length FLAG-tagged recombinant HDAC3 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
Inhibition of full length FLAG-tagged recombinant HDAC3 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
|
[PMID: 23964961]
|
|
HeLa
|
IC50 |
0.107 μM
Compound: 1, SAHA, Vorinostat
|
Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
|
[PMID: 21476600]
|
|
HeLa
|
IC50 |
0.11 μM
Compound: 1, SAHA
|
Inhibition of HDAC in HeLa cells by fluorescent activity assay
Inhibition of HDAC in HeLa cells by fluorescent activity assay
|
[PMID: 17477518]
|
|
HeLa
|
IC50 |
0.11 μM
Compound: 2, SAHA
|
Inhibition of HeLa cell HDAC
Inhibition of HeLa cell HDAC
|
[PMID: 16723227]
|
|
HeLa
|
IC50 |
0.11 μM
Compound: 2, SAHA
|
Inhibition of HDAC in HeLa cell lysates
Inhibition of HDAC in HeLa cell lysates
|
[PMID: 17904843]
|
|
HeLa
|
IC50 |
0.11 μM
Compound: 6, SAHA
|
Inhibition of HDAC1/HDAC2 in human HeLa cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay
Inhibition of HDAC1/HDAC2 in human HeLa cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assay
|
[PMID: 25906087]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis
Inhibition of HDAC1/3/5/8 in human HeLa cell extract using Boc-Lys-(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorometric analysis
|
[PMID: 23510562]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading flourimeter analysis
Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading flourimeter analysis
|
[PMID: 25811792]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine side chain of histone as substrate measured after 30 mins by fluorometric assay
Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine side chain of histone as substrate measured after 30 mins by fluorometric assay
|
[PMID: 28011426]
|
|
HeLa
|
IC50 |
0.11 μM
Compound: SAHA, Zolinza
|
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by UV-vis spectrophotometer analysis
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by UV-vis spectrophotometer analysis
|
[PMID: 26100440]
|
|
HeLa
|
IC50 |
0.119 μM
Compound: Vorinostat, SAHA, Zolinza
|
Inhibition of full length FLAG-tagged recombinant HDAC1 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
Inhibition of full length FLAG-tagged recombinant HDAC1 (unknown origin) transfected in human HeLa cells assessed as deacetylation of [3H]-acetylated histones after 2 hrs by scintillation counting analysis
|
[PMID: 23964961]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by microplate reader analysis
Inhibition of HDAC1/HDAC2 in human HeLa cells nuclear extract preincubated for 5 mins before Boc-Lys (acetyl)-AMC substrate addition for 30 mins by microplate reader analysis
|
[PMID: 26629857]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cells using Fluor de Lys as substrate by fluorescence assay
Inhibition of HDAC in human HeLa cells using Fluor de Lys as substrate by fluorescence assay
|
[PMID: 23639537]
|
|
HeLa
|
IC50 |
0.13 μM
Compound: 1, SAHA
|
Inhibition of HDAC1/2 in human HeLa cell extracts using acetylated histone peptide as substrate after 30 mins
Inhibition of HDAC1/2 in human HeLa cell extracts using acetylated histone peptide as substrate after 30 mins
|
[PMID: 24525003]
|
|
HeLa
|
IC50 |
0.13 μM
Compound: SAHA, Vorinostat
|
Inhibition of HDAC in human HeLa cell extract using fluor de Lys as substrate after 15 mins by fluorometric analysis
Inhibition of HDAC in human HeLa cell extract using fluor de Lys as substrate after 15 mins by fluorometric analysis
|
[PMID: 23792316]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/HDAC2 isolated from human HeLa cells incubated for 30 mins by Color de Lys assay
Inhibition of HDAC1/HDAC2 isolated from human HeLa cells incubated for 30 mins by Color de Lys assay
|
10.1039/C4MD00203B
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in HeLa cells
Inhibition of HDAC in HeLa cells
|
[PMID: 17662606]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cytosolic extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
Inhibition of HDAC in human HeLa cytosolic extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
|
[PMID: 30245394]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC6 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
Inhibition of HDAC6 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
|
[PMID: 30245394]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
|
[PMID: 30879863]
|
|
HeLa
|
IC50 |
0.168 μM
Compound: 3; SAHA
|
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay
|
[PMID: 30901208]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cells nuclear extracts by fluorometric assay
Inhibition of HDAC in human HeLa cells nuclear extracts by fluorometric assay
|
[PMID: 23116147]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
|
[PMID: 30245394]
|
|
HeLa
|
IC50 |
0.19 μM
Compound: 1, SAHA
|
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated with enzyme for 5 mins prior to substrate addition measured after 30 mins by fluorescence assay
|
[PMID: 23493449]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
Inhibition of HDAC1 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
|
[PMID: 26555243]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/HDAC2 in human HeLa nuclear extract
Inhibition of HDAC1/HDAC2 in human HeLa nuclear extract
|
[PMID: 30245394]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 in human HeLa cells nuclear extracts using acetylated histone peptide as substrate after 30 mins by Color de Lys assay
Inhibition of HDAC1/2 in human HeLa cells nuclear extracts using acetylated histone peptide as substrate after 30 mins by Color de Lys assay
|
[PMID: 26216016]
|
|
HeLa
|
IC50 |
0.195 μM
Compound: 1, SAHA, Vorinostat
|
Inhibition of HDAC6 in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
Inhibition of HDAC6 in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
|
[PMID: 21476600]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa nuclear extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
Inhibition of HDAC in human HeLa nuclear extract using Fluor-de-lys as substrate measured after 60 mins by fluorescence assay
|
[PMID: 30245394]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine as substrate after 30 mins by spectrophotometric analysis
Inhibition of HDAC in human HeLa cell nuclear extract using acetylated lysine as substrate after 30 mins by spectrophotometric analysis
|
[PMID: 24702857]
|
|
HeLa
|
IC50 |
0.28 μM
Compound: 2, (SAHA, vorinostat)
|
Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetry
Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetry
|
[PMID: 19419205]
|
|
HeLa
|
IC50 |
|
Inhibitory concentration against histone deacetylase of HeLa cells
Inhibitory concentration against histone deacetylase of HeLa cells
|
[PMID: 15603949]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC from human HeLa cells
Inhibition of HDAC from human HeLa cells
|
[PMID: 18247554]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC8 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
Inhibition of HDAC8 in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
|
[PMID: 26555243]
|
|
HeLa
|
IC50 |
|
Inhibition of class 1 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC addition and measured after 30 mins by fluorescence based assay
Inhibition of class 1 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC addition and measured after 30 mins by fluorescence based assay
|
[PMID: 32267687]
|
|
HeLa
|
IC50 |
0.48 μM
Compound: 1, SAHA, Vorinostat
|
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorimetric analysis
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorimetric analysis
|
[PMID: 24766560]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa nuclear extract
Inhibition of HDAC in human HeLa nuclear extract
|
[PMID: 30245394]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (Ac)-AMC as substrate after 60 mins by fluorometric analysis
|
[PMID: 26555243]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell extract incubated for 1 hr by colorimetric activity assay
Inhibition of HDAC in human HeLa cell extract incubated for 1 hr by colorimetric activity assay
|
10.1039/C4MD00350K
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC from human HeLa cells by fluorogenic enzyme assay
Inhibition of HDAC from human HeLa cells by fluorogenic enzyme assay
|
[PMID: 19457659]
|
|
HeLa
|
IC50 |
|
Growth inhibition of human HeLa cells after 48 hrs by MTT assay
Growth inhibition of human HeLa cells after 48 hrs by MTT assay
|
[PMID: 24702857]
|
|
HeLa
|
IC50 |
0.98 μM
Compound: Zolinza, SAHA
|
Inhibition of HDAC derived from human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorimetry
Inhibition of HDAC derived from human HeLa cell nuclear extract using Boc-Lys(acetyl)-AMC as substrate incubated for 5 mins prior to substrate addition measured after 30 mins by fluorimetry
|
[PMID: 22698782]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extract by fluorescence assay
|
[PMID: 20036560]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC8 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
Inhibition of HDAC8 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
|
[PMID: 30245394]
|
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells overexpressing HDAC by resazurin dye reduction assay
Cytotoxicity against human HeLa cells overexpressing HDAC by resazurin dye reduction assay
|
[PMID: 21080629]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 28336407]
|
|
HeLa
|
IC50 |
1.72 μM
Compound: Vorinostat
|
Cytotoxicity against human HeLa cells assessed as cell growth inhibition
Cytotoxicity against human HeLa cells assessed as cell growth inhibition
|
[PMID: 38107170]
|
|
HeLa
|
IC50 |
|
Cytotoxicity against HeLa cells
Cytotoxicity against HeLa cells
|
[PMID: 17691763]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 29500131]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 29533873]
|
|
HeLa
|
IC50 |
107.8 nM
Compound: 1, SAHA
|
Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorescence assay
Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorescence assay
|
[PMID: 26122774]
|
|
HeLa
|
IC50 |
11 nM
Compound: Vorinostat
|
Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract preincubated for 20 mins followed by addition of HDAC green as substrate measured after 60 mins by fluorescence analysis
Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract preincubated for 20 mins followed by addition of HDAC green as substrate measured after 60 mins by fluorescence analysis
|
[PMID: 27597246]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assay
|
[PMID: 27186676]
|
|
HeLa
|
IC50 |
12 nM
Compound: Vorinostat
|
Inhibition of human HDAC in HeLa cell nuclear extract by fluorometric assay using Fluor de Lys substrate
Inhibition of human HDAC in HeLa cell nuclear extract by fluorometric assay using Fluor de Lys substrate
|
[PMID: 26475519]
|
|
HeLa
|
IC50 |
12.28 μM
Compound: 1, SAHA
|
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26122774]
|
|
HeLa
|
IC50 |
12.28 μM
Compound: 6, SAHA
|
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 25906087]
|
|
HeLa
|
IC50 |
120.06 nM
Compound: 1; SAHA
|
Inhibition of HDAC activity in human HeLa cell nuclear extract using fluorometric substrate measured after 30 mins by fluorescence assay
Inhibition of HDAC activity in human HeLa cell nuclear extract using fluorometric substrate measured after 30 mins by fluorescence assay
|
[PMID: 27886544]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 in human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
Inhibition of HDAC1/2 in human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
|
[PMID: 32267687]
|
|
HeLa
|
IC50 |
1270 nM
Compound: 1; SAHA
|
Antiproliferative activity against human HeLa cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
HeLa
|
IC50 |
131.26 nM
Compound: 1; SAHA
|
Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Lys(Ac)-pNA as substrate after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Lys(Ac)-pNA as substrate after 30 mins by fluorescence assay
|
[PMID: 28395150]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell extracts assessed as inhibition of substrate deacetylation using Boc-Lys (acetyl)-AMC as substrate by fluorescence based assay
Inhibition of HDAC in human HeLa cell extracts assessed as inhibition of substrate deacetylation using Boc-Lys (acetyl)-AMC as substrate by fluorescence based assay
|
[PMID: 32247729]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extracts using Fluor de Lys as substrate by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extracts using Fluor de Lys as substrate by fluorescence assay
|
[PMID: 24119555]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell extract using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa cell extract using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by fluorescence assay
|
[PMID: 25462271]
|
|
HeLa
|
IC50 |
147 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 21476600]
|
|
HeLa
|
IC50 |
15 nM
Compound: Vorinostat
|
Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assay
Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assay
|
[PMID: 26741358]
|
|
HeLa
|
IC50 |
|
Inhibition of Class 1 histone deacetylase isolated from human HeLa cell nuclear extracts using Boc-Lys (acetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay
Inhibition of Class 1 histone deacetylase isolated from human HeLa cell nuclear extracts using Boc-Lys (acetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescence assay
|
[PMID: 26349626]
|
|
HeLa
|
IC50 |
159 nM
Compound: Vorinostat
|
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substrate pretreated for 5 mins followed by substrate addition measured after 30 mins by UV-absorption method
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substrate pretreated for 5 mins followed by substrate addition measured after 30 mins by UV-absorption method
|
[PMID: 28371677]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extracts using (Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extracts using (Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay
|
[PMID: 28336407]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 in human HeLa cell nuclear extracts preincubated for 5 mins followed by substrate addition measured after 0.5 hrs by Color de Lys assay
Inhibition of HDAC1/2 in human HeLa cell nuclear extracts preincubated for 5 mins followed by substrate addition measured after 0.5 hrs by Color de Lys assay
|
[PMID: 26149591]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate incubated for 2 hrs prior to substrate addition measured after 30 mins by fluorescence assay
Inhibition of HDAC1/2 in human HeLa cells using Boc-Lys (acetyl)-AMC as substrate incubated for 2 hrs prior to substrate addition measured after 30 mins by fluorescence assay
|
[PMID: 26386821]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
Inhibition of HDAC6 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
|
[PMID: 21984958]
|
|
HeLa
|
IC50 |
|
Inhibition of class 2 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
Inhibition of class 2 HDAC n human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
|
[PMID: 32267687]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC8 from human HeLa cells nuclear extract by cell free fluorimetric assay
Inhibition of HDAC8 from human HeLa cells nuclear extract by cell free fluorimetric assay
|
[PMID: 19093884]
|
|
HeLa
|
IC50 |
|
Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assay
Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assay
|
[PMID: 20167479]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC8 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
Inhibition of HDAC8 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
|
[PMID: 22260166]
|
|
HeLa
|
IC50 |
1989 nM
Compound: SAHA, Vorinostat
|
Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
|
[PMID: 23622981]
|
|
HeLa
|
IC50 |
|
Anticancer activity against human HeLa cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
Anticancer activity against human HeLa cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
|
[PMID: 36244186]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 28057407]
|
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by alamar-blue cell viability assay
Cytotoxicity against human HeLa cells after 72 hrs by alamar-blue cell viability assay
|
[PMID: 19301902]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human Hela cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human Hela cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
|
[PMID: 31991336]
|
|
HeLa
|
IC50 |
2.5 μM
Compound: Vorinostat
|
Antiproliferative activity against human HeLa cells measured after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells measured after 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37057760]
|
|
HeLa
|
IC50 |
2.59 μM
Compound: SAHA, Vorinostat
|
Inhibition of HDAC in human HeLa cell nuclear extracts using Color de LysTM after 30 mins
Inhibition of HDAC in human HeLa cell nuclear extracts using Color de LysTM after 30 mins
|
[PMID: 24095016]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs
Antiproliferative activity against human HeLa cells after 48 hrs
|
[PMID: 24262004]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay
|
[PMID: 35939996]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 33021789]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 24296013]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay
Antiproliferative activity against human HeLa cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34624191]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells incubated for 24 to 48 hrs by CCK-8 assay
Antiproliferative activity against human HeLa cells incubated for 24 to 48 hrs by CCK-8 assay
|
[PMID: 39145486]
|
|
HeLa
|
IC50 |
2.8 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assay
Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assay
|
[PMID: 23707260]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
HeLa
|
IC50 |
2.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human HeLa cells by CCK8 assay
Antiproliferative activity against human HeLa cells by CCK8 assay
|
[PMID: 30660827]
|
|
HeLa
|
IC50 |
2000 nM
Compound: 2, SAHA
|
Inhibition of HDAC8 in human HeLa cells nuclear extract using Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 30 mins by spectrophotometry
Inhibition of HDAC8 in human HeLa cells nuclear extract using Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 30 mins by spectrophotometry
|
[PMID: 21984958]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC6 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
Inhibition of HDAC6 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
|
[PMID: 22260166]
|
|
HeLa
|
IC50 |
27 nM
Compound: SAHA, Vorinostat
|
Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
|
[PMID: 23622981]
|
|
HeLa
|
IC50 |
|
Selectivity ratio IC50 for HDAC8 to IC50 for HDAC in human HeLa cells nuclear extract
Selectivity ratio IC50 for HDAC8 to IC50 for HDAC in human HeLa cells nuclear extract
|
[PMID: 20669972]
|
|
HeLa
|
IC50 |
3.1 μM
Compound: II, SAHA
|
Antiproliferative activity against human HeLa cells after 4 hrs by WST-1 assay
Antiproliferative activity against human HeLa cells after 4 hrs by WST-1 assay
|
[PMID: 18672316]
|
|
HeLa
|
IC50 |
3.55 μM
Compound: Vorinostat
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 28371677]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
Cytotoxicity against human HeLa cells after 72 hrs by MTS assay
|
[PMID: 25899338]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
Inhibition of HDAC1 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
|
[PMID: 22260166]
|
|
HeLa
|
IC50 |
38 nM
Compound: SAHA, Vorinostat
|
Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
|
[PMID: 23622981]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cells
Inhibition of HDAC in human HeLa cells
|
[PMID: 18558669]
|
|
HeLa
|
IC50 |
|
Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation
Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation
|
[PMID: 35944852]
|
|
HeLa
|
IC50 |
4.52 μM
Compound: Vorinostat
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
|
[PMID: 33261898]
|
|
HeLa
|
IC50 |
4.52 μM
Compound: Vorinostat
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
|
[PMID: 35255412]
|
|
HeLa
|
IC50 |
4.52 μM
Compound: Vorinostat
|
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 35477142]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 30879863]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against siRNA-induced BAX knock down human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against siRNA-induced BAX knock down human HeLa cells after 48 hrs by MTT assay
|
[PMID: 33021789]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extract
Inhibition of HDAC in human HeLa cell nuclear extract
|
[PMID: 20143778]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
Inhibition of HDAC1 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
|
[PMID: 21984958]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
Inhibition of HDAC3-NCoR2 in human HeLa cells nuclear extract using Fluor-de-Lys as substrate after 30 mins by spectrophotometry
|
[PMID: 21984958]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/HDAC2 in human HeLa cell extract incubated for 5 mins prior to substrate addition measured after 30 mins by microtitre plate reader analysis
Inhibition of HDAC1/HDAC2 in human HeLa cell extract incubated for 5 mins prior to substrate addition measured after 30 mins by microtitre plate reader analysis
|
[PMID: 25311567]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by celltiter-blue viability assay
Antiproliferative activity against human HeLa cells after 72 hrs by celltiter-blue viability assay
|
[PMID: 18809328]
|
|
HeLa
|
IC50 |
460 nM
Compound: 1, vorinostat
|
Antiproliferative activity against human HeLa cells by CellTiter-Blue cell viability assay
Antiproliferative activity against human HeLa cells by CellTiter-Blue cell viability assay
|
[PMID: 18370373]
|
|
HeLa
|
IC50 |
|
Inhibition of HeLa cell proliferation
Inhibition of HeLa cell proliferation
|
[PMID: 16987657]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 from human HeLa cells
Inhibition of HDAC1/2 from human HeLa cells
|
[PMID: 19854643]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 32151834]
|
|
HeLa
|
IC50 |
5.21 μM
Compound: 1; SAHA
|
Cytotoxicity against human HeLa cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36242988]
|
|
HeLa
|
IC50 |
5.45 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
HeLa
|
IC50 |
|
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
10.1039/C4MD00203B
|
|
HeLa
|
IC50 |
|
Inhibition of human HDAC in HeLa cells by flour de lys assay
Inhibition of human HDAC in HeLa cells by flour de lys assay
|
[PMID: 18397827]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 from human HeLa cells nuclear extract by cell free fluorimetric assay
Inhibition of HDAC1/2 from human HeLa cells nuclear extract by cell free fluorimetric assay
|
[PMID: 19093884]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assay
Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assay
|
[PMID: 19914074]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extracts
Inhibition of HDAC in human HeLa cell nuclear extracts
|
[PMID: 20669972]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using Fluor de Lys as substrate after 15 mins by fluorometric analysis
|
[PMID: 22260166]
|
|
HeLa
|
IC50 |
65 nM
Compound: SAHA, Vorinostat
|
Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assay
|
[PMID: 23622981]
|
|
HeLa
|
IC50 |
67 nM
Compound: SAHA, Vorinostat
|
Inhibition of HDAC in human HeLa cells using Ac-Arg-Gly-Lys(Ac)-AMC as fluorescent substrate after 20 mins by fluorescence assay
Inhibition of HDAC in human HeLa cells using Ac-Arg-Gly-Lys(Ac)-AMC as fluorescent substrate after 20 mins by fluorescence assay
|
[PMID: 21621883]
|
|
HeLa
|
IC50 |
67 nM
Compound: SAHA, Zolinza
|
Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-Arg-Gly-Lys(Ac)-AMC substrate by fluorimetry
Inhibition of HDAC in human HeLa cell nuclear extracts using Ac-Arg-Gly-Lys(Ac)-AMC substrate by fluorimetry
|
[PMID: 22435669]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLA cell nuclear extracts
Inhibition of HDAC in human HeLA cell nuclear extracts
|
[PMID: 31400938]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HeLa
|
IC50 |
|
Inhibition of human HDAC in HeLa cells by fluorescent activity assay
Inhibition of human HDAC in HeLa cells by fluorescent activity assay
|
[PMID: 19223622]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC6 from human HeLa cells nuclear extract by cell free fluorimetric assay
Inhibition of HDAC6 from human HeLa cells nuclear extract by cell free fluorimetric assay
|
[PMID: 19093884]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human Hela cell lysate using Fluor-de-Lys as substrate compound pretreated for 30 mins before substrate addition by fluorescence assay
Inhibition of HDAC in human Hela cell lysate using Fluor-de-Lys as substrate compound pretreated for 30 mins before substrate addition by fluorescence assay
|
[PMID: 23089527]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC from human HeLa cells
Inhibition of HDAC from human HeLa cells
|
[PMID: 18672316]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetric assay
Inhibition of HDAC in human HeLa cell nuclear extracts by fluorimetric assay
|
[PMID: 20884208]
|
|
HeLa
|
IC50 |
87 nM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in human HeLa cells nuclear extract using fluor de Lys as substrate preincubated for 5 mins by fluorometric analysis
Inhibition of HDAC in human HeLa cells nuclear extract using fluor de Lys as substrate preincubated for 5 mins by fluorometric analysis
|
[PMID: 21080647]
|
|
HeLa
|
IC50 |
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HeLa
|
IC50 |
9.69 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human HeLa cells after 48 hrs by MTT assay
Growth inhibition of human HeLa cells after 48 hrs by MTT assay
|
[PMID: 24095016]
|
|
HeLa
|
IC50 |
|
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using color de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 30 min by microtiter plate reader analysis
Inhibition of HDAC1/2 in human HeLa cell nuclear extract using color de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 30 min by microtiter plate reader analysis
|
[PMID: 26907204]
|
|
HeLa
|
IC50 |
96.4 nM
Compound: 1, SAHA
|
Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
Inhibition of HDAC in human HeLa cell nuclear extract after 30 mins by fluorescence microplate reader
|
[PMID: 22439863]
|
|
HeLa
|
IC50 |
98.35 μM
Compound: 1; SAHA
|
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate measured after 30 mins by fluorescence assay
|
[PMID: 31655430]
|
|
HeLa
|
IC50 |
>= 0.05 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC2 in HeLa cell lysates
Inhibition of HDAC2 in HeLa cell lysates
|
[PMID: 17892933]
|
|
HeLa S3
|
IC50 |
|
Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
|
[PMID: 28337317]
|
|
HeLa S3
|
IC50 |
|
Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
|
[PMID: 28337317]
|
|
HeLa S3
|
IC50 |
|
Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
|
[PMID: 28337317]
|
|
HeLa S3
|
IC50 |
|
Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISA
|
[PMID: 28337317]
|
|
Hep 3B2
|
GI50 |
0.69 μM
Compound: 1, SAHA
|
Growth inhibition of human Hep3B cells after 48 hrs by SRB assay
Growth inhibition of human Hep3B cells after 48 hrs by SRB assay
|
[PMID: 22439863]
|
|
Hep 3B2
|
GI50 |
|
Antiproliferative activity against human Hep3B cells after 48 hrs by SRB assay
Antiproliferative activity against human Hep3B cells after 48 hrs by SRB assay
|
[PMID: 21712146]
|
|
Hep 3B2
|
GI50 |
> 410 nM
Compound: Vorinostat
|
Cytotoxicity against human Hep3B cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human Hep3B cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
Hep 3B2
|
IC50 |
|
Cytotoxicity against human Hep3B cells
Cytotoxicity against human Hep3B cells
|
[PMID: 23906422]
|
|
Hep 3B2
|
IC50 |
2.3 μM
Compound: Vorinostat
|
Cytotoxicity against human Hep3B cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human Hep3B cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
Hep 3B2
|
IC50 |
|
Antiproliferative activity against human Hep3B2 cells after hrs by ATP content assay
Antiproliferative activity against human Hep3B2 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
Hep 3B2
|
IC50 |
2.6 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
Hep 3B2
|
IC50 |
5.4 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23707260]
|
|
Hep 3B2
|
IC50 |
|
Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
HepG2
|
CC50 |
12 μM
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by CellTiter-Glo assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by CellTiter-Glo assay
|
[PMID: 30973727]
|
|
HepG2
|
EC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 23820574]
|
|
HepG2
|
EC50 |
2.5 μM
Compound: suberoylanilide
|
Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis
Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis
|
[PMID: 20966043]
|
|
HepG2
|
EC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by XTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by XTT assay
|
[PMID: 21548582]
|
|
HepG2
|
EC50 |
35.5 μM
Compound: suberoylanilide
|
Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
|
[PMID: 20966043]
|
|
HepG2
|
EC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by XTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by XTT assay
|
[PMID: 21548582]
|
|
HepG2
|
EC50 |
|
Antiproliferative activity against human HepG2 cells after 24 hrs by XTT assay
Antiproliferative activity against human HepG2 cells after 24 hrs by XTT assay
|
[PMID: 21548582]
|
|
HepG2
|
GI50 |
21.96 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
|
[PMID: 29500130]
|
|
HepG2
|
GI50 |
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
|
[PMID: 34500130]
|
|
HepG2
|
GI50 |
3.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human HepG2 cells after 72 hrs by MTT assay
Growth inhibition of human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 22435669]
|
|
HepG2
|
GI50 |
4600 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human HepG2 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human HepG2 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
HepG2
|
GI50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 19822426]
|
|
HepG2
|
IC50 |
0.14 μM
Compound: SAHA, Vorinostat
|
Antimalarial activity against exo-erythrocytic form of Plasmodium berghei infected in human HepG2 cells after 48 hrs
Antimalarial activity against exo-erythrocytic form of Plasmodium berghei infected in human HepG2 cells after 48 hrs
|
[PMID: 24904967]
|
|
HepG2
|
IC50 |
0.15 μM
Compound: SAHA, Vorinostat
|
Antimalarial activity against exo-erythrocytic form of Plasmodium berghei infected in human HepG2 cells
Antimalarial activity against exo-erythrocytic form of Plasmodium berghei infected in human HepG2 cells
|
[PMID: 24904967]
|
|
HepG2
|
IC50 |
0.18 μM
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
HepG2
|
IC50 |
0.18 μg/mL
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells
Antiproliferative activity against human HepG2 cells
|
[PMID: 31945642]
|
|
HepG2
|
IC50 |
0.18 μg/mL
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
HepG2
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
|
[PMID: 35238576]
|
|
HepG2
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
HepG2
|
IC50 |
|
Inhibition of human HepG2 cells
Inhibition of human HepG2 cells
|
[PMID: 18247554]
|
|
HepG2
|
IC50 |
0.61 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells
Antiproliferative activity against human HepG2 cells
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
0.68 μM
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human Hep-G2 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
Cytotoxicity against human Hep-G2 cells assessed as inhibition of cell proliferation measured after 72 hrs by ATPlite assay
|
[PMID: 34185525]
|
|
HepG2
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells incubated for 72 hrs measured by MTT assay
Cytotoxicity against human HepG2 cells incubated for 72 hrs measured by MTT assay
|
[PMID: 37498552]
|
|
HepG2
|
IC50 |
1.18 μM
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells incubated for 72 hrs by CCK-8 assay
Cytotoxicity against human HepG2 cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 35175762]
|
|
HepG2
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human HepG2 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
1.27 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
|
[PMID: 34237620]
|
|
HepG2
|
IC50 |
1.49 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against human HepG2 cells after 48 hrs
Cytotoxicity against human HepG2 cells after 48 hrs
|
[PMID: 24904967]
|
|
HepG2
|
IC50 |
1.54 μM
Compound: 1; SAHA
|
Anticancer activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
Anticancer activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
|
[PMID: 36215854]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay
Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after hrs by ATP content assay
Antiproliferative activity against human HepG2 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
HepG2
|
IC50 |
1.7 μM
Compound: SAHA; 112
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by CCK-8 assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by CCK-8 assay
|
[PMID: 31881454]
|
|
HepG2
|
IC50 |
1.7 μM
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability
|
[PMID: 30660827]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HepG2
|
IC50 |
13 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
|
[PMID: 35608269]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
HepG2
|
IC50 |
2.1 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35152694]
|
|
HepG2
|
IC50 |
2.43 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
2.5 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells measured after 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
HepG2
|
IC50 |
2.57 μM
Compound: Vorinostat
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
HepG2
|
IC50 |
2.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human HepG2 cells by CCK8 assay
Antiproliferative activity against human HepG2 cells by CCK8 assay
|
[PMID: 30660827]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by CCK8 assay
|
[PMID: 26211462]
|
|
HepG2
|
IC50 |
3.2 ng/mL
Compound: SAHA; 1
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 3 days by trypan blue assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 3 days by trypan blue assay
|
[PMID: 35586423]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 29396364]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34624191]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
|
HepG2
|
IC50 |
|
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 28885834]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 30455152]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells by MTT assay
Antiproliferative activity against human HepG2 cells by MTT assay
|
[PMID: 31546197]
|
|
HepG2
|
IC50 |
5.75 μM
Compound: 1; SAHA
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36242988]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 31120744]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay
|
[PMID: 30851694]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human HepG2 cells after 48 hrs by CCK-8 assay
|
[PMID: 35939996]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 29288941]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 30108831]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
|
[PMID: 35041998]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2-A16-CD81EGFP cells assessed as inhibition of cell growth incubated for 24 hrs followed by medium transfer and incubation in multimode plate for 48 hrs by CellTiterGlo reagent based luminescence assay
Cytotoxicity against human HepG2-A16-CD81EGFP cells assessed as inhibition of cell growth incubated for 24 hrs followed by medium transfer and incubation in multimode plate for 48 hrs by CellTiterGlo reagent based luminescence assay
|
[PMID: 33360801]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
HepG2
|
IC50 |
9.06 μM
Compound: I-1; SAHA
|
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 35245830]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
|
[PMID: 29348808]
|
|
HepG2
|
IC50 |
|
Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
Growth inhibition of human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 20143840]
|
|
HepG2
|
IC50 |
|
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
HepG2
|
IC50 |
|
Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
Hepatocyte
|
EC50 |
|
Compound was tested for anti-proliferative activity in human hepatocytes
Compound was tested for anti-proliferative activity in human hepatocytes
|
[PMID: 14698179]
|
|
Hepatocyte
|
GI50 |
|
Growth inhibition of human hepatocytes after 21 hrs by MTT assay
Growth inhibition of human hepatocytes after 21 hrs by MTT assay
|
[PMID: 17662606]
|
|
Hs-578T
|
GI50 |
|
Antiproliferative activity against human Hs578T cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human Hs578T cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
Hs-578T
|
GI50 |
4.83 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human Hs578T cells after 48 hrs by SRB assay
Cytotoxicity against human Hs578T cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
Hs-578T
|
GI50 |
5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human Hs 578T cells after 72 hrs by MTS assay
Growth inhibition of human Hs 578T cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
Hs68
|
IC50 |
|
Cytotoxicity against human HS68 cells after 72 hrs by MTT assay
Cytotoxicity against human HS68 cells after 72 hrs by MTT assay
|
[PMID: 23570542]
|
|
HuP-T3
|
IC50 |
0.8 μM
Compound: 1a, SAHA
|
Growth inhibition of human HUPT3 cells after 72 hrs by MTS assay
Growth inhibition of human HUPT3 cells after 72 hrs by MTS assay
|
[PMID: 20055418]
|
|
HuP-T3
|
IC50 |
|
Cytotoxicity against human Hup T3 cells after 72 hrs by MTT assay
Cytotoxicity against human Hup T3 cells after 72 hrs by MTT assay
|
[PMID: 18494463]
|
|
HuP-T3
|
IC50 |
|
Antiproliferative activity against human HupT3 cells after 72 hrs by MTT assay
Antiproliferative activity against human HupT3 cells after 72 hrs by MTT assay
|
[PMID: 18642892]
|
|
HuP-T3
|
IC50 |
|
Antiproliferative activity against human HUPT3 cells by MTT assay
Antiproliferative activity against human HUPT3 cells by MTT assay
|
[PMID: 19419863]
|
|
HuT78
|
EC50 |
|
Pro-apoptotic activity in human HUT78 cells after 18 hrs by caspase-Glo 3/7 assay
Pro-apoptotic activity in human HUT78 cells after 18 hrs by caspase-Glo 3/7 assay
|
[PMID: 30122227]
|
|
HuT78
|
GI50 |
|
Cytotoxicity against human HUT78 cells after 72 hrs by MTS assay
Cytotoxicity against human HUT78 cells after 72 hrs by MTS assay
|
[PMID: 24900743]
|
|
HuT78
|
GI50 |
295 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human HUT78 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human HUT78 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
HuT78
|
GI50 |
3 μM
Compound: 2, SAHA, Vorinostat
|
Cytotoxicity against human HUT78 cells after 72 hrs by MTS-PMS assay
Cytotoxicity against human HUT78 cells after 72 hrs by MTS-PMS assay
|
[PMID: 24164245]
|
|
HuT78
|
GI50 |
|
Growth inhibition of human HUT78 cells after 72 hrs by SRB assay
Growth inhibition of human HUT78 cells after 72 hrs by SRB assay
|
[PMID: 20884208]
|
|
HuT78
|
IC50 |
0.68 μM
Compound: Vorinostat
|
Cytotoxicity against human HuT78 cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
Cytotoxicity against human HuT78 cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
|
[PMID: 37875056]
|
|
HuT78
|
IC50 |
0.71 μM
Compound: 1; SAHA
|
Cytotoxicity against human HuT78 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human HuT78 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 33588178]
|
|
Huh-7
|
CC50 |
0.64 μM
Compound: Vorinostat
|
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability incubated for 3 days by MTT assay
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability incubated for 3 days by MTT assay
|
[PMID: 31201063]
|
|
Huh-7
|
CC50 |
|
Cytotoxicity against human HuH7 cells assessed as inhibition of cell viability after 3 days by CellTiter 96 assay
Cytotoxicity against human HuH7 cells assessed as inhibition of cell viability after 3 days by CellTiter 96 assay
|
[PMID: 25490700]
|
|
Huh-7
|
EC50 |
0.36 μM
Compound: 5, SAHA
|
Antiviral activity against HCV genotype 1b infected in human Huh7 cells after 3 days by luciferase reporter gene assay
Antiviral activity against HCV genotype 1b infected in human Huh7 cells after 3 days by luciferase reporter gene assay
|
[PMID: 25490700]
|
|
Huh-7
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human Huh-7 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human Huh-7 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
Huh-7
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
Huh-7
|
IC50 |
|
Antiproliferative activity against human HuH7 cells after 72 hrs by CellTiter blue-reagent based assay
Antiproliferative activity against human HuH7 cells after 72 hrs by CellTiter blue-reagent based assay
|
[PMID: 30645113]
|
|
Huh-7
|
IC50 |
|
Cytotoxicity against human Huh-7 cells incubated for 72 hrs measured by MTT assay
Cytotoxicity against human Huh-7 cells incubated for 72 hrs measured by MTT assay
|
[PMID: 37498552]
|
|
Huh-7
|
IC50 |
1.95 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human HuH-7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human HuH-7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
Huh-7
|
IC50 |
|
Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
Huh-7
|
IC50 |
|
Antiproliferative activity against human HuH7 cells after 96 hrs by MTT assay
Antiproliferative activity against human HuH7 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
Huh-7
|
IC50 |
|
Antiproliferative activity against human HuH7 cells after 48 hrs by MTT assay
Antiproliferative activity against human HuH7 cells after 48 hrs by MTT assay
|
[PMID: 29288941]
|
|
Huh-7
|
IC50 |
|
Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
|
[PMID: 31120744]
|
|
IGROV-1
|
GI50 |
|
Antiproliferative activity against human IGROV1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human IGROV1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
IGROV-1
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human IGROV1 cells after 72 hrs by MTS assay
Growth inhibition of human IGROV1 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
IGROV-1
|
IC50 |
|
Antiproliferative activity against cisplatin-resistant human IGROV1 cells after 72 hrs
Antiproliferative activity against cisplatin-resistant human IGROV1 cells after 72 hrs
|
[PMID: 19084294]
|
|
IGROV-1
|
IC50 |
|
Antiproliferative activity against human IGROV1 cells after 72 hrs
Antiproliferative activity against human IGROV1 cells after 72 hrs
|
[PMID: 19084294]
|
|
IGROV-1
|
IC50 |
|
Antiproliferative activity against human IGROV1 cells assessed as growth inhibition after 72 hrs
Antiproliferative activity against human IGROV1 cells assessed as growth inhibition after 72 hrs
|
[PMID: 24742384]
|
|
IGROV-1
|
IC50 |
|
Antiproliferative activity against p53 defective cis-platinum-resistant human IGROV1/Pt1 cells assessed as growth inhibition after 72 hrs
Antiproliferative activity against p53 defective cis-platinum-resistant human IGROV1/Pt1 cells assessed as growth inhibition after 72 hrs
|
[PMID: 24742384]
|
|
IGROV-1
|
IC50 |
|
Growth inhibition of human IGROV1 cells after 72 hrs
Growth inhibition of human IGROV1 cells after 72 hrs
|
[PMID: 26376355]
|
|
IGROV-1
|
IC50 |
|
Growth inhibition of human IGROV1/Pt1 cells after 72 hrs
Growth inhibition of human IGROV1/Pt1 cells after 72 hrs
|
[PMID: 26376355]
|
|
IGROV-1
|
IC50 |
|
Antiproliferative activity against human IGROV1 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
Antiproliferative activity against human IGROV1 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
|
[PMID: 26890116]
|
|
IMR-32
|
IC50 |
0.62 μM
Compound: Vorinostat
|
Antiproliferative activity against human IMR32 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
Antiproliferative activity against human IMR32 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
|
[PMID: 31391882]
|
|
JeKo-1
|
IC50 |
|
Antiproliferative activity against human JeKo-1 cells incubated for 48 hrs by resazurin based microplate reader analysis
Antiproliferative activity against human JeKo-1 cells incubated for 48 hrs by resazurin based microplate reader analysis
|
[PMID: 37647727]
|
|
JeKo-1
|
IC50 |
|
Antiproliferative activity against human JeKo1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
Antiproliferative activity against human JeKo1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
|
[PMID: 26890114]
|
|
JeKo-1
|
IC50 |
|
Antiproliferative activity against human JeKo-1 cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based assay
Antiproliferative activity against human JeKo-1 cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based assay
|
[PMID: 39047608]
|
|
JeKo-1
|
IC50 |
|
Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
|
[PMID: 29150335]
|
|
JeKo-1
|
IC50 |
|
Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
Antiproliferative activity against human JeKo1 cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
Jurkat
|
EC50 |
|
Growth inhibition of human Jurkat cells after 44 hrs by MTT assay
Growth inhibition of human Jurkat cells after 44 hrs by MTT assay
|
[PMID: 28337317]
|
|
Jurkat
|
EC50 |
0.87 μM
Compound: 1a, SAHA
|
Antiproliferative activity against human Jurkat JA16 cells after 48 hrs by cell titer-glo assay
Antiproliferative activity against human Jurkat JA16 cells after 48 hrs by cell titer-glo assay
|
[PMID: 20218673]
|
|
Jurkat
|
EC50 |
|
Cytotoxicity against human Jurkat cells assessed as cell proliferation after 70 hrs by MTS assay
Cytotoxicity against human Jurkat cells assessed as cell proliferation after 70 hrs by MTS assay
|
[PMID: 25974739]
|
|
Jurkat
|
EC50 |
1600 nM
Compound: Vorinostat
|
Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by Steady-Glo luciferase assay
Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by Steady-Glo luciferase assay
|
[PMID: 32676157]
|
|
Jurkat
|
EC50 |
|
Compound was tested for anti-proliferative activity in Jurkat human leukemia cell line
Compound was tested for anti-proliferative activity in Jurkat human leukemia cell line
|
[PMID: 14698179]
|
|
Jurkat
|
GI50 |
|
Cytotoxicity against human Jurkat cells after 72 hrs by MTS assay
Cytotoxicity against human Jurkat cells after 72 hrs by MTS assay
|
[PMID: 24900743]
|
|
Jurkat
|
GI50 |
|
Growth inhibition of human Jurkat cells after 72 hrs by XTT assay
Growth inhibition of human Jurkat cells after 72 hrs by XTT assay
|
[PMID: 24900500]
|
|
Jurkat
|
GI50 |
|
Growth inhibition of human Jurkat cells
Growth inhibition of human Jurkat cells
|
[PMID: 37429084]
|
|
Jurkat
|
IC50 |
0.04 μM
Compound: 4, SAHA
|
Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-Ac as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-Ac as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
|
[PMID: 24261862]
|
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 33668008]
|
|
Jurkat
|
IC50 |
0.1 μM
Compound: Vorinostat
|
Cytotoxicity against human Jurkat cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
Cytotoxicity against human Jurkat cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
|
[PMID: 37989057]
|
|
Jurkat
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
Jurkat
|
IC50 |
0.27 μM
Compound: 3; SAHA
|
Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30901208]
|
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 35043615]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
|
[PMID: 29533873]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850]
|
|
Jurkat
|
IC50 |
0.47 μM
Compound: Vorinostat
|
Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
|
[PMID: 36351184]
|
|
Jurkat
|
IC50 |
0.47 μM
Compound: Vorinostat
|
Cytotoxicity against human Jurkat cells measured for 72 hrs by celltiter-glo assay
Cytotoxicity against human Jurkat cells measured for 72 hrs by celltiter-glo assay
|
[PMID: 38714044]
|
|
Jurkat
|
IC50 |
0.59 μM
Compound: 1; SAHA
|
Antiproliferative activity against human Jurkat cells
Antiproliferative activity against human Jurkat cells
|
[PMID: 27541357]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells
Antiproliferative activity against human Jurkat cells
|
[PMID: 28953386]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells after 72 hrs by MTT assay
|
[PMID: 30243158]
|
|
Jurkat
|
IC50 |
0.61 μM
Compound: Vorinostat
|
Antiproliferative activity against human Jurkat cells
Antiproliferative activity against human Jurkat cells
|
[PMID: 37875056]
|
|
Jurkat
|
IC50 |
0.68 μM
Compound: Vorinostat
|
Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based assay
|
[PMID: 37875056]
|
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 48 hrs MTT assay
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 48 hrs MTT assay
|
[PMID: 33668008]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
Antiproliferative activity against human Jurkat cells after 48 hrs by MTT assay
|
[PMID: 29500131]
|
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 23547652]
|
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
Cytotoxicity against human Jurkat cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 24304348]
|
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells
Cytotoxicity against human Jurkat cells
|
[PMID: 25240614]
|
|
Jurkat
|
IC50 |
|
Inhibition of HDAC1 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
Inhibition of HDAC1 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
|
[PMID: 27177826]
|
|
Jurkat
|
IC50 |
|
Inhibition of HDAC3 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
Inhibition of HDAC3 in human Jurkat cells extract after 30 mins by immunoprecipitation assay
|
[PMID: 27177826]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
|
[PMID: 37079967]
|
|
Jurkat
|
IC50 |
|
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 24 hrs MTT assay
Cytotoxicity against human Jurkat cells assessed as reduction in cell viability measured after 24 hrs MTT assay
|
[PMID: 33668008]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human Jurkat cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
Jurkat
|
IC50 |
|
Antiproliferative activity against human Jurkat cells incubated for 24 to 48 hrs by CCK-8 assay
Antiproliferative activity against human Jurkat cells incubated for 24 to 48 hrs by CCK-8 assay
|
[PMID: 39145486]
|
|
Jurkat
|
IC50 |
> 10 μM
Compound: 4, SAHA
|
Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-TFA as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
Inhibition of HDAC4 in human Jurkat E6.1 cells using Boc-Lys-TFA as substrate incubated for 2 hrs prior to substrate addition measured after 3 hrs by fluorescence assay
|
[PMID: 24261862]
|
|
Jurkat
|
IC50 |
> 30 μM
Compound: 3; SAHA
|
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36449947]
|
|
K562
|
EC50 |
2.2 μM
Compound: 1a, SAHA
|
Antiproliferative activity against human K562 cells after 48 hrs by cell titer-glo assay
Antiproliferative activity against human K562 cells after 48 hrs by cell titer-glo assay
|
[PMID: 20218673]
|
|
K562
|
ED50 |
0.45791 μM
Compound: 5; SAHA
|
Potentiation of (-)-lomaiviticin A-induced cytotoxicity against human K562 cells assessed as (-)-lomaiviticin A ED50 at compound to (-)-lomaiviticin A ratio of 5000:1 after 48 hrs by cell titer-glo luminescence assay (Rvb = 0.23776 nM)
Potentiation of (-)-lomaiviticin A-induced cytotoxicity against human K562 cells assessed as (-)-lomaiviticin A ED50 at compound to (-)-lomaiviticin A ratio of 5000:1 after 48 hrs by cell titer-glo luminescence assay (Rvb = 0.23776 nM)
|
[PMID: 27177826]
|
|
K562
|
ED50 |
1.24803 μM
Compound: 5; SAHA
|
Cytotoxicity against human K562 cells assessed as decrease in cell viability after 48 hrs by cell titer-glo luminescence assay
Cytotoxicity against human K562 cells assessed as decrease in cell viability after 48 hrs by cell titer-glo luminescence assay
|
[PMID: 27177826]
|
|
K562
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human K562 cells after 72 hrs by MTS assay
Growth inhibition of human K562 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
K562
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human K562 cells after 72 hrs by MTS assay
Growth inhibition of human K562 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
K562
|
GI50 |
|
Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
|
[PMID: 25800646]
|
|
K562
|
GI50 |
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
|
[PMID: 34500130]
|
|
K562
|
GI50 |
1.97 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
K562
|
GI50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 28629630]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35152694]
|
|
K562
|
IC50 |
|
Inhibition of HDAC in human K562 cell extract using Fluor-de-Lys deacetylase as substrate preincubated for 45 mins measured after 15 mins by fluorescence assay
Inhibition of HDAC in human K562 cell extract using Fluor-de-Lys deacetylase as substrate preincubated for 45 mins measured after 15 mins by fluorescence assay
|
[PMID: 24328302]
|
|
K562
|
IC50 |
0.17 μM
Compound: 1; SAHA
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
|
[PMID: 27142751]
|
|
K562
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
K562
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
K562
|
IC50 |
0.21 nM
Compound: 1; SAHA
|
Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
|
[PMID: 36622852]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells incubated for 48 hrs by resazurin based microplate reader analysis
Antiproliferative activity against human K562 cells incubated for 48 hrs by resazurin based microplate reader analysis
|
[PMID: 37647727]
|
|
K562
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human K562 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human K562 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
|
[PMID: 35238576]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human K562 cells incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 36549114]
|
|
K562
|
IC50 |
0.55 μM
Compound: 1; SAHA
|
Antiproliferative activity against human K562 cells incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human K562 cells incubated for 48 hrs by CCK8 assay
|
[PMID: 37037787]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells measured after 48 hrs by MTT assay
|
[PMID: 35041998]
|
|
K562
|
IC50 |
0.64 μM
Compound: SAHA, Vorinostat
|
Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay
|
[PMID: 23792316]
|
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells
Cytotoxicity against human K562 cells
|
[PMID: 23644210]
|
|
K562
|
IC50 |
0.645 μM
Compound: vorinostat
|
Antiproliferative activity against human K562 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
Antiproliferative activity against human K562 cells assessed as cell viability after 72 hrs by CellTitre-Glo luminescent assay
|
[PMID: 26629860]
|
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells after 72 hrs by CellTiter-Glo assay
Cytotoxicity against human K562 cells after 72 hrs by CellTiter-Glo assay
|
[PMID: 30245394]
|
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells
Cytotoxicity against human K562 cells
|
[PMID: 17691763]
|
|
K562
|
IC50 |
0.67 μM
Compound: 6, SAHA
|
Cytotoxicity against human K562 cells after 72 hrs by alamar-blue cell viability assay
Cytotoxicity against human K562 cells after 72 hrs by alamar-blue cell viability assay
|
[PMID: 19301902]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 29533873]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
K562
|
IC50 |
0.75 μM
Compound: 3, SAHA
|
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
|
[PMID: 18038969]
|
|
K562
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34624191]
|
|
K562
|
IC50 |
|
Anti-proliferative activity against human K562 cells after 48 hrs by MTT assay
Anti-proliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 28947154]
|
|
K562
|
IC50 |
1 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by trypan blue dye exclusion method
Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by trypan blue dye exclusion method
|
[PMID: 25221651]
|
|
K562
|
IC50 |
1.02 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
K562
|
IC50 |
1.03 μM
Compound: 3; SAHA
|
Synergistic antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
Synergistic antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs in presence of ruxolitinib by MTT assay
|
[PMID: 30901208]
|
|
K562
|
IC50 |
1.11 μM
Compound: 3; SAHA
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30901208]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
|
[PMID: 36272186]
|
|
K562
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human K562 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37057760]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells by MTT assay
Antiproliferative activity against human K562 cells by MTT assay
|
[PMID: 33132117]
|
|
K562
|
IC50 |
1.35 μM
Compound: Vorinostat
|
Cytotoxicity against human K562 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human K562 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 35926141]
|
|
K562
|
IC50 |
1.41 μM
Compound: Vorinostat
|
Antiproliferative activity against human K562 cells by MTT assay
Antiproliferative activity against human K562 cells by MTT assay
|
[PMID: 37875056]
|
|
K562
|
IC50 |
1.44 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human K562 cells incubated for 48 hrs by MTT assay
|
[PMID: 31413795]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 28336407]
|
|
K562
|
IC50 |
1.49 μM
Compound: Vorinostat
|
Cytotoxicity against human K562 cells assessed as cell growth inhibition
Cytotoxicity against human K562 cells assessed as cell growth inhibition
|
[PMID: 38107170]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells incubated for 24 hrs by CCK8 assay
Antiproliferative activity against human K562 cells incubated for 24 hrs by CCK8 assay
|
[PMID: 32247729]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 25311567]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
|
[PMID: 36622852]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 28419930]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
K562
|
IC50 |
1.95 μM
Compound: Vorinostat
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 28371677]
|
|
K562
|
IC50 |
|
Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.
Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.
|
[PMID: 12419380]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 96 hrs by MTT assay
Antiproliferative activity against human K562 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
K562
|
IC50 |
|
Concentration required to inhibit Histone Deacetylase (HDAC) from K562 erythroleukemia cells
Concentration required to inhibit Histone Deacetylase (HDAC) from K562 erythroleukemia cells
|
[PMID: 12270175]
|
|
K562
|
IC50 |
|
Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cells
Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cells
|
[PMID: 14552787]
|
|
K562
|
IC50 |
|
Inhibition of HDAC in human K562 nuclear extract
Inhibition of HDAC in human K562 nuclear extract
|
[PMID: 31655430]
|
|
K562
|
IC50 |
|
Inhibition of HDAC from human K562 cells
Inhibition of HDAC from human K562 cells
|
[PMID: 18247554]
|
|
K562
|
IC50 |
143 nM
Compound: 24; SAHA
|
Inhibition of HDAC in human K562 cell extracts using (QSY-7)-RGGRGLGK(Ac)-GGARRHRK(TAMRA)NH2 as substrate preincubated for 30 mins followed by addition of endoproteinase Lys-C and measured after 2 hrs by fluorescence assay
Inhibition of HDAC in human K562 cell extracts using (QSY-7)-RGGRGLGK(Ac)-GGARRHRK(TAMRA)NH2 as substrate preincubated for 30 mins followed by addition of endoproteinase Lys-C and measured after 2 hrs by fluorescence assay
|
[PMID: 31536895]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
|
[PMID: 35939996]
|
|
K562
|
IC50 |
2.24 μM
Compound: 3; SAHA
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36449947]
|
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
K562
|
IC50 |
2.93 μM
Compound: XII; SAHA
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
K562
|
IC50 |
3.24 μM
Compound: SA, SAHA
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
K562
|
IC50 |
3.32 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 21476600]
|
|
K562
|
IC50 |
3.77 μM
Compound: 1, SAHA
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 24525003]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 30879863]
|
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 26349626]
|
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human K562 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26149591]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based assay
|
[PMID: 39047608]
|
|
K562
|
IC50 |
38 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against human K562 cells assessed as reduction in cell viability
Cytotoxicity against human K562 cells assessed as reduction in cell viability
|
[PMID: 26264503]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells by MTT assay
Antiproliferative activity against human K562 cells by MTT assay
|
[PMID: 31546197]
|
|
K562
|
IC50 |
|
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
Cytotoxicity against human K562 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells after 48 hrs by CCK-8 assay
|
[PMID: 29940115]
|
|
K562
|
IC50 |
|
Antiproliferative activity against human K562 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
K562/A02
|
IC50 |
|
Antiproliferative activity against human K562/A02 cells overexpressing P-gp by MTT assay
Antiproliferative activity against human K562/A02 cells overexpressing P-gp by MTT assay
|
[PMID: 33132117]
|
|
KB
|
IC50 |
0.75 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human KB cells by MTT assay
Cytotoxicity against human KB cells by MTT assay
|
[PMID: 24766560]
|
|
KB
|
IC50 |
|
Cytotoxicity against human KB cells after 72 hrs by MTS assay
Cytotoxicity against human KB cells after 72 hrs by MTS assay
|
[PMID: 25899338]
|
|
KB-V1
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human KB-V1 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human KB-V1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
KB-V1
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human vinblastine resistant KB-V1 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human vinblastine resistant KB-V1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
KG-1
|
IC50 |
|
Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35152694]
|
|
KG-1
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
KG-1
|
IC50 |
0.59 μM
Compound: 1; SAHA
|
Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
Cytotoxicity against human KG-1 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
|
[PMID: 33588178]
|
|
KG-1
|
IC50 |
0.64 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
KG-1
|
IC50 |
0.68 μM
Compound: 1, SAHA
|
Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26122774]
|
|
KG-1
|
IC50 |
0.68 μM
Compound: 6, SAHA
|
Cytotoxicity against human KG1 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human KG1 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 25906087]
|
|
KG-1
|
IC50 |
0.79 μM
Compound: SAHA; 6
|
Antiproliferative activity against human KG-1 cells incubated for 72 hrs by celltiter-glo luminescent assay
Antiproliferative activity against human KG-1 cells incubated for 72 hrs by celltiter-glo luminescent assay
|
[PMID: 39178382]
|
|
KG-1
|
IC50 |
|
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
|
[PMID: 26907204]
|
|
KG-1
|
IC50 |
|
Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human KG1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
10.1039/C4MD00203B
|
|
KG-1
|
IC50 |
1.15 μM
Compound: 1, SAHA
|
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
|
[PMID: 24525003]
|
|
KG-1
|
IC50 |
|
Antiproliferative activity against human KG1 cells after 72 hrs by MTT assay
Antiproliferative activity against human KG1 cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
KG-1
|
IC50 |
1.59 μM
Compound: SA, SAHA
|
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
KG-1
|
IC50 |
|
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
KG-1
|
IC50 |
|
Antiproliferative activity against human KG-1 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human KG-1 cells incubated for 72 hrs by MTT assay
|
[PMID: 32961382]
|
|
KG-1
|
IC50 |
|
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
|
[PMID: 26216016]
|
|
KM-H2
|
IC50 |
|
Antiproliferative activity against human KM-H2 cells after 72 hrs by MTT assay
Antiproliferative activity against human KM-H2 cells after 72 hrs by MTT assay
|
[PMID: 29150335]
|
|
KM12
|
GI50 |
|
Antiproliferative activity against human KM12 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human KM12 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
KM12
|
GI50 |
1.88 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human KM12 cells after 48 hrs by SRB assay
Cytotoxicity against human KM12 cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
KM12
|
GI50 |
2 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human KM12 cells after 72 hrs by MTS assay
Growth inhibition of human KM12 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
KM3/BTZ
|
IC50 |
|
Antiproliferative activity against bortezomib resistant human KM3/BTZ cells in presence of bortezomib incubated for 48 hrs by MTT assay
Antiproliferative activity against bortezomib resistant human KM3/BTZ cells in presence of bortezomib incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
KM3/BTZ
|
IC50 |
|
Antiproliferative activity against bortezomib resistant human KM3/BTZ cells incubated for 48 hrs by MTT assay
Antiproliferative activity against bortezomib resistant human KM3/BTZ cells incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
KMS-12-BM
|
EC50 |
0.94 μM
Compound: 3; SAHA
|
Antiproliferative activity against human KMS-12-BM cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human KMS-12-BM cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 31627059]
|
|
KMS-12-BM
|
IC50 |
0.94 μM
Compound: 1; SAHA
|
Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo assay
Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo assay
|
[PMID: 27541357]
|
|
KMS-12-BM
|
IC50 |
|
Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo luminescent assay
Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo luminescent assay
|
[PMID: 28953386]
|
|
KMS-12-BM
|
IC50 |
|
Antiproliferative activity against human KMS-12-BM cells after 72 hrs by MTT assay
Antiproliferative activity against human KMS-12-BM cells after 72 hrs by MTT assay
|
[PMID: 30243158]
|
|
KYSE-30
|
IC50 |
3 μM
Compound: Vorinostat
|
Antiproliferative activity against human KYSE-30 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human KYSE-30 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
KYSE-450
|
IC50 |
6.478 μM
Compound: Vorinostat
|
Antiproliferative activity against human KYSE-450 cells
Antiproliferative activity against human KYSE-450 cells
|
[PMID: 37875056]
|
|
KYSE-510
|
IC50 |
0.59 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in cisplatin resistant human KYSE-510 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in cisplatin resistant human KYSE-510 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
KYSE-510
|
IC50 |
0.7 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in cisplatin sensitive human KYSE-510 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in cisplatin sensitive human KYSE-510 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
KYSE-510
|
IC50 |
4.62 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against cisplatin sensitive human KYSE-510 cells after 72 hrs by MTT assay
Cytotoxicity against cisplatin sensitive human KYSE-510 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
KYSE-510
|
IC50 |
4.66 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against cisplatin resistant human KYSE-510 cells after 72 hrs by MTT assay
Cytotoxicity against cisplatin resistant human KYSE-510 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
Kasumi 1
|
IC50 |
|
Inhibition of cell viability in human Kasumi 1 cells incubated for 4 days in presence of GSK5032 by CCK8 assay
Inhibition of cell viability in human Kasumi 1 cells incubated for 4 days in presence of GSK5032 by CCK8 assay
|
[PMID: 39264152]
|
|
Kasumi 1
|
IC50 |
|
Inhibition of cell viability in human Kasumi 1 cells incubated for 4 days by CCK8 assay
Inhibition of cell viability in human Kasumi 1 cells incubated for 4 days by CCK8 assay
|
[PMID: 39264152]
|
|
Kasumi 1
|
IC50 |
620 nM
Compound: Vorinostat
|
Cytotoxicity against human Kasumi 1 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human Kasumi 1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
L-363
|
IC50 |
0.48 μM
Compound: 4; SAHA
|
Antiproliferative activity against human L-363 cells
Antiproliferative activity against human L-363 cells
|
[PMID: 37652098]
|
|
L-428
|
IC50 |
|
Antiproliferative activity against human L428 cells after 72 hrs by MTT assay
Antiproliferative activity against human L428 cells after 72 hrs by MTT assay
|
[PMID: 29150335]
|
|
L-428
|
IC50 |
|
Antiproliferative activity against human L-428 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human L-428 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
L02
|
IC50 |
|
Antiproliferative activity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
L02
|
IC50 |
|
Cytotoxicity against human HL7702 cells measured after 72 hrs by MTT assay
Cytotoxicity against human HL7702 cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
L02
|
IC50 |
|
Cytotoxicity against human L02 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 33021789]
|
|
L02
|
IC50 |
5.45 μM
Compound: Vorinostat
|
cytotoxicity against human HL-7702 cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
cytotoxicity against human HL-7702 cells assessed as reduction of cell viability incubated for 72 hrs by MTT assay
|
[PMID: 33493830]
|
|
L02
|
IC50 |
|
Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
L02
|
IC50 |
|
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
L02
|
IC50 |
|
Cytotoxicity against human HL7702 cells incubated for 48 hrs by resazurin based microplate reader analysis
Cytotoxicity against human HL7702 cells incubated for 48 hrs by resazurin based microplate reader analysis
|
[PMID: 37647727]
|
|
L02
|
IC50 |
|
Cytotoxicity against human L02 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
L02
|
IC50 |
> 50000 nM
Compound: SAHA
|
Antiproliferative activity against human HL7702 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human HL7702 cells incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
L1210
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
L1210
|
IC50 |
|
Antiproliferative activity against mouse L1210 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against mouse L1210 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
L6
|
IC50 |
|
Cytotoxicity against rat L6 cells
Cytotoxicity against rat L6 cells
|
[PMID: 25563890]
|
|
LNCaP
|
GI50 |
|
Antiproliferative activity against human LNCaP cells assessed as growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human LNCaP cells assessed as growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 37633202]
|
|
LNCaP
|
IC50 |
|
Antiproliferative activity against human LNCAP cells
Antiproliferative activity against human LNCAP cells
|
[PMID: 20143778]
|
|
LNCaP
|
IC50 |
|
Antiproliferative activity against human LNCAP cells incubated for 96 hrs by resazurin assay
Antiproliferative activity against human LNCAP cells incubated for 96 hrs by resazurin assay
|
[PMID: 32435375]
|
|
LNCaP
|
IC50 |
|
Antiproliferative activity against human LNCap by MTT assay
Antiproliferative activity against human LNCap by MTT assay
|
[PMID: 18166465]
|
|
LNCaP
|
IC50 |
|
Concentration required to inhibit human LNCaP prostate carcinoma cells
Concentration required to inhibit human LNCaP prostate carcinoma cells
|
[PMID: 16033284]
|
|
LNCaP
|
IC50 |
|
Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 28057407]
|
|
LNCaP
|
IC50 |
1.34 μM
Compound: 1; SAHA
|
Antiproliferative activity against human LNCaP cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human LNCaP cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
LNCaP
|
IC50 |
|
Cytotoxicity against human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
Cytotoxicity against human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 28131715]
|
|
LNCaP
|
IC50 |
|
Cytotoxicity against human LNCAP cells assessed as growth inhibition by MTS assay
Cytotoxicity against human LNCAP cells assessed as growth inhibition by MTS assay
|
[PMID: 23547652]
|
|
LNCaP
|
IC50 |
|
Cytotoxicity against androgen-dependent human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
Cytotoxicity against androgen-dependent human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 24304348]
|
|
LNCaP
|
IC50 |
|
Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
|
[PMID: 25240614]
|
|
LNCaP
|
IC50 |
|
Inhibition of HDAC6 in human LNCAP cells assessed as tubulin acetylation by Western blot analysis
Inhibition of HDAC6 in human LNCAP cells assessed as tubulin acetylation by Western blot analysis
|
[PMID: 25240614]
|
|
LOX IMVI
|
EC50 |
|
Inhibition of human LOX-IMVI cells
Inhibition of human LOX-IMVI cells
|
[PMID: 18247554]
|
|
LOX IMVI
|
EC50 |
1.3 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human LOX-IMVI cells
Effective Concentration of compound to inhibit the growth of human LOX-IMVI cells
|
[PMID: 15715470]
|
|
LOX IMVI
|
GI50 |
1 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human LOXIMVI cells after 72 hrs by MTS assay
Growth inhibition of human LOXIMVI cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
LOX IMVI
|
GI50 |
|
Antiproliferative activity against human LOXIMVI cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human LOXIMVI cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
LOX IMVI
|
GI50 |
1.3 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
LOX IMVI
|
GI50 |
1.39 μM
Compound: 1, SAHA
|
Growth inhibition of LOX-IMVI cells by SRB assay
Growth inhibition of LOX-IMVI cells by SRB assay
|
[PMID: 17477518]
|
|
LOX IMVI
|
GI50 |
1.39 μM
Compound: 2, SAHA
|
Antiproliferative activity against human LOX-IMVI cells by SRB assay
Antiproliferative activity against human LOX-IMVI cells by SRB assay
|
[PMID: 16723227]
|
|
LOX IMVI
|
GI50 |
|
Growth inhibition of human LOX-IMVI cells after 21 hrs by MTT assay
Growth inhibition of human LOX-IMVI cells after 21 hrs by MTT assay
|
[PMID: 17662606]
|
|
LP-1
|
IC50 |
|
Antiproliferative activity against human LP-1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
Antiproliferative activity against human LP-1 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
|
[PMID: 26890114]
|
|
LoVo
|
GI50 |
1700 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human LoVo cells after 72 hrs by WST-1 assay
Antiproliferative activity against human LoVo cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human LoVo cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells assessed as reduction in cell number after 72 hrs by cell counter analysis
Antiproliferative activity against human LoVo cells assessed as reduction in cell number after 72 hrs by cell counter analysis
|
[PMID: 26890116]
|
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells by MTT assay
Antiproliferative activity against human LoVo cells by MTT assay
|
[PMID: 31546197]
|
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human LoVo cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26555243]
|
|
LoVo
|
IC50 |
|
Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
|
[PMID: 30108831]
|
|
M14
|
GI50 |
|
Antiproliferative activity against human M14 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human M14 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
M14
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human M14 cells after 72 hrs by MTS assay
Growth inhibition of human M14 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
MC-38
|
GI50 |
|
Antiproliferative activity against mouse MC38 cells measured after 72 hrs by CCK8 assay
Antiproliferative activity against mouse MC38 cells measured after 72 hrs by CCK8 assay
|
[PMID: 34783558]
|
|
MC-38
|
GI50 |
2.74 μM
Compound: 3; SAHA
|
Antiproliferative activity against mouse MC38 cells after 72 hrs by CCK-8 assay
Antiproliferative activity against mouse MC38 cells after 72 hrs by CCK-8 assay
|
[PMID: 35390714]
|
|
MC-38
|
IC50 |
|
Antiproliferative activity against mouse MC38 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against mouse MC38 cells after 48 hrs by CCK-8 assay
|
[PMID: 35939996]
|
|
MC-38
|
IC50 |
2.22 μM
Compound: 1; SAHA
|
Antiproliferative activity against mouse MC38 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against mouse MC38 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
MCF-10A
|
GI50 |
9.6 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MCF10A cells after 48 hrs by MTT assay
Growth inhibition of human MCF10A cells after 48 hrs by MTT assay
|
[PMID: 22435669]
|
|
MCF-10A
|
IC50 |
0.42 μM
Compound: 6; SAHA
|
Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
|
[PMID: 30078609]
|
|
MCF-10A
|
IC50 |
|
Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
Cytotoxicity against ER negative human MCF10A cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
|
[PMID: 30078609]
|
|
MCF-10A
|
IC50 |
|
Antiproliferative activity against human MCF10A cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF10A cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
MCF-10A
|
IC50 |
|
Cytotoxicity against human MCF10A cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MCF10A cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
MCF-10A
|
IC50 |
|
Cytotoxicity against human MCF10A cells after 96 hrs by MTA reduction assay
Cytotoxicity against human MCF10A cells after 96 hrs by MTA reduction assay
|
[PMID: 23293738]
|
|
MCF-10A
|
IC50 |
|
Antitumor activity against human MCF10A cells
Antitumor activity against human MCF10A cells
|
[PMID: 19534534]
|
|
MCF-10A
|
IC50 |
> 50 μM
Compound: 1; SAHA
|
Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 48 hrs by SRB assay
Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 48 hrs by SRB assay
|
[PMID: 32180916]
|
|
MCF7
|
CC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human MCF7 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19441846]
|
|
MCF7
|
EC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition by SRB assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition by SRB assay
|
[PMID: 34591488]
|
|
MCF7
|
EC50 |
0.65 μM
Compound: 3; SAHA
|
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
|
[PMID: 31627059]
|
|
MCF7
|
GI50 |
0.45 μM
Compound: 1, SAHA
|
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24119555]
|
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 25800646]
|
|
MCF7
|
GI50 |
|
Cytotoxicity against human MCF7 cells after 48 hrs by Sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 48 hrs by Sulforhodamine B assay
|
[PMID: 23639537]
|
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth measured after 6 days by WST8 assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth measured after 6 days by WST8 assay
|
[PMID: 34610548]
|
|
MCF7
|
GI50 |
1.34 μM
Compound: 1, SAHA
|
Growth inhibition of human MCF7 cells after 96 hrs by MTT assay
Growth inhibition of human MCF7 cells after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 28629630]
|
|
MCF7
|
GI50 |
2 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 22435669]
|
|
MCF7
|
GI50 |
2.19 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
MCF7
|
GI50 |
2.2 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF-7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human MCF-7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
|
[PMID: 34500130]
|
|
MCF7
|
GI50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS-PMS assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS-PMS assay
|
[PMID: 27614919]
|
|
MCF7
|
GI50 |
3.02 μM
Compound: 1; SAHA
|
Anticancer activity against human MCF7 cells overexpressing HDAC1 and HDAC2 assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B assay
Anticancer activity against human MCF7 cells overexpressing HDAC1 and HDAC2 assessed as inhibition of cell growth incubated for 48 hrs by sulforhodamine B assay
|
[PMID: 37847303]
|
|
MCF7
|
GI50 |
|
Growth inhibition of human MCF7 cells after 72 hrs by XTT assay
Growth inhibition of human MCF7 cells after 72 hrs by XTT assay
|
[PMID: 24900500]
|
|
MCF7
|
IC50 |
0.13 μg/mL
Compound: SAHA
|
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
|
[PMID: 22036991]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 8 hrs by CCK8 assay
|
[PMID: 35238576]
|
|
MCF7
|
IC50 |
0.18 μg/mL
Compound: Vorinostat
|
Anticancer activity against human MCF7 cells
Anticancer activity against human MCF7 cells
|
[PMID: 31945642]
|
|
MCF7
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Inhibition of cell viability in human MCF7 cells incubated for 12 days with every 3 day treatment by Alamar blue staining based analysis
Inhibition of cell viability in human MCF7 cells incubated for 12 days with every 3 day treatment by Alamar blue staining based analysis
|
[PMID: 38838548]
|
|
MCF7
|
IC50 |
0.32 μM
Compound: 6; SAHA
|
Antiproliferative activity against human MCF7 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
Antiproliferative activity against human MCF7 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
|
[PMID: 26613635]
|
|
MCF7
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
MCF7
|
IC50 |
0.45 μM
Compound: 6; SAHA
|
Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
|
[PMID: 30078609]
|
|
MCF7
|
IC50 |
0.493 μM
Compound: Vorinostat
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
0.58 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
MCF7
|
IC50 |
0.65 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 27541357]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 28953386]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells
Antiproliferative activity against human MCF7 cells
|
[PMID: 29945795]
|
|
MCF7
|
IC50 |
0.68 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 32151834]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 30243158]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
MCF7
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
MCF7
|
IC50 |
0.91 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MCF7 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
MCF7
|
IC50 |
0.95 μM
Compound: 6; SAHA
|
Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
Cytotoxicity against ER positive human MCF7 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
|
[PMID: 30078609]
|
|
MCF7
|
IC50 |
1.03 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells
Antiproliferative activity against human MCF7 cells
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Antiproliferative against human MCF-7 cells assessed as reduction in cell viability by MTT assay
Antiproliferative against human MCF-7 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 33045329]
|
|
MCF7
|
IC50 |
1.1 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
|
[PMID: 24766560]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
MCF7
|
IC50 |
1.15 μM
Compound: SAHA, Vorinostat
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 21924799]
|
|
MCF7
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells incubated for 96 hrs by resazurin assay
Antiproliferative activity against human MCF7 cells incubated for 96 hrs by resazurin assay
|
[PMID: 32435375]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37057760]
|
|
MCF7
|
IC50 |
|
Inhibition of MCF7 cell proliferation (mean of two experiments)
Inhibition of MCF7 cell proliferation (mean of two experiments)
|
[PMID: 17095213]
|
|
MCF7
|
IC50 |
|
Inhibition of MCF7 cell proliferation (mean of two experiments)
Inhibition of MCF7 cell proliferation (mean of two experiments)
|
[PMID: 17107790]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 24296013]
|
|
MCF7
|
IC50 |
1.6 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
|
[PMID: 29360358]
|
|
MCF7
|
IC50 |
1.7 μM
Compound: SAHA; 112
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK-8 assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK-8 assay
|
[PMID: 31881454]
|
|
MCF7
|
IC50 |
1.7 μM
Compound: Vorinostat
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability
|
[PMID: 30660827]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
|
[PMID: 32738414]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 29396364]
|
|
MCF7
|
IC50 |
2.29 μM
Compound: Vorinostat
|
Cytotoxicity against human MCF7 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
Cytotoxicity against human MCF7 cells assessed as growth inhibition by measuring cellular ATP level after 72 hrs by cell-titer glo assay
|
[PMID: 23829483]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
|
[PMID: 35043615]
|
|
MCF7
|
IC50 |
2.43 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth measured for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
|
[PMID: 22260166]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTT assay
|
[PMID: 25993269]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 33965842]
|
|
MCF7
|
IC50 |
2.5 μM
Compound: SAHA; vorinostat
|
Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay
Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay
|
[PMID: 26725029]
|
|
MCF7
|
IC50 |
2.5 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells measured after 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay
|
[PMID: 34624191]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human MCF7 cells after 48 hrs by CCK-8 assay
|
[PMID: 29317150]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability in presence of erlotinib by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability in presence of erlotinib by MTT assay
|
[PMID: 32320239]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after hrs by ATP content assay
Antiproliferative activity against human MCF7 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
MCF7
|
IC50 |
2.8 μM
Compound: Vorinostat
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 32791404]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 21714538]
|
|
MCF7
|
IC50 |
2.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells by CCK8 assay
Antiproliferative activity against human MCF7 cells by CCK8 assay
|
[PMID: 30660827]
|
|
MCF7
|
IC50 |
2.92 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
MCF7
|
IC50 |
3.13 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37875056]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
10.1039/C4MD00203B
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 28057407]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells by MTT assay
Antiproliferative activity against human MCF7 cells by MTT assay
|
[PMID: 31546197]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity in human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
Antiproliferative activity in human MCF7 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
|
[PMID: 32061484]
|
|
MCF7
|
IC50 |
3.56 μM
Compound: 4; SAHA
|
Antiproliferative activity against human MCF7 cells
Antiproliferative activity against human MCF7 cells
|
[PMID: 37652098]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells incubated for 72 hrs by MTT assay
|
[PMID: 38452727]
|
|
MCF7
|
IC50 |
3.78 μM
Compound: SA, SAHA
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 30629434]
|
|
MCF7
|
IC50 |
|
Cytotoxic activity against human MCF7 cells after 24 hrs by MTT assay
Cytotoxic activity against human MCF7 cells after 24 hrs by MTT assay
|
[PMID: 29496367]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
|
[PMID: 33077264]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 32320239]
|
|
MCF7
|
IC50 |
4.2 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 26741358]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
|
[PMID: 30245394]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
|
MCF7
|
IC50 |
4.4 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against human MCF7 cells expressing ERalpha and ERbeta assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells expressing ERalpha and ERbeta assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23786452]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 29288941]
|
|
MCF7
|
IC50 |
4.5 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 26475519]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by MTT assay
|
[PMID: 28987602]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37116762]
|
|
MCF7
|
IC50 |
4.83 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MCF7 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells after 72 hrs by CCK8 assay
|
[PMID: 30045621]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 35272009]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells measured after 72 hrs
Antiproliferative activity against human MCF7 cells measured after 72 hrs
|
[PMID: 35697181]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
MCF7
|
IC50 |
|
Growth inhibition of MCF7 cells
Growth inhibition of MCF7 cells
|
[PMID: 17958342]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells up to 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells up to 72 hrs by MTT assay
|
[PMID: 27541357]
|
|
MCF7
|
IC50 |
6.17 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by SRB assay
|
[PMID: 32180916]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay
|
[PMID: 36996717]
|
|
MCF7
|
IC50 |
6.42 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay
|
[PMID: 24185378]
|
|
MCF7
|
IC50 |
6.5 μM
Compound: Vorinostat
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
|
[PMID: 35608269]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
|
[PMID: 17691763]
|
|
MCF7
|
IC50 |
60.2 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
Growth inhibition of human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 24095016]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
MCF7
|
IC50 |
7.11 μM
Compound: 1; SAHA
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36242988]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 96 hrs by MTA reduction assay
Cytotoxicity against human MCF7 cells after 96 hrs by MTA reduction assay
|
[PMID: 23293738]
|
|
MCF7
|
IC50 |
8.5 μM
Compound: 81, SAHA
|
Antitumor activity against human MCF7 cells
Antitumor activity against human MCF7 cells
|
[PMID: 19534534]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
10.1039/C5MD00247H
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
MCF7
|
IC50 |
|
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
|
[PMID: 30819618]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by SRB assay
|
[PMID: 34116381]
|
|
MCF7
|
IC50 |
|
Inhibition of human MCF7 cells
Inhibition of human MCF7 cells
|
[PMID: 18247554]
|
|
MCF7
|
IC50 |
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
MCF7
|
IC50 |
> 50 μM
Compound: 1; SAHA
|
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 33668008]
|
|
MCF7
|
IC50 |
> 50 μM
Compound: Vorinostat
|
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
|
[PMID: 37989057]
|
|
MDA-MB-231
|
EC50 |
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
|
[PMID: 31627059]
|
|
MDA-MB-231
|
EC50 |
|
Inhibition of human MDA-MB-231 cells
Inhibition of human MDA-MB-231 cells
|
[PMID: 18247554]
|
|
MDA-MB-231
|
EC50 |
1.5 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human MDA-MB-231 cells
Effective Concentration of compound to inhibit the growth of human MDA-MB-231 cells
|
[PMID: 15715470]
|
|
MDA-MB-231
|
GI50 |
0.66 μM
Compound: 1, SAHA
|
Growth inhibition of human MDA-MB-231 cells by SRB assay
Growth inhibition of human MDA-MB-231 cells by SRB assay
|
[PMID: 17477518]
|
|
MDA-MB-231
|
GI50 |
0.66 μM
Compound: 2, SAHA
|
Antiproliferative activity against human MDA-MB-231 cells by SRB assay
Antiproliferative activity against human MDA-MB-231 cells by SRB assay
|
[PMID: 16723227]
|
|
MDA-MB-231
|
GI50 |
|
Growth inhibition of human MDA-MB-231 cells after 21 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 21 hrs by MTT assay
|
[PMID: 17662606]
|
|
MDA-MB-231
|
GI50 |
0.97 μM
Compound: 1, SAHA
|
Growth inhibition of human MDA-MB-231 cells after 48 hrs by SRB assay
Growth inhibition of human MDA-MB-231 cells after 48 hrs by SRB assay
|
[PMID: 22439863]
|
|
MDA-MB-231
|
GI50 |
1 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 22435669]
|
|
MDA-MB-231
|
GI50 |
1.81 μM
Compound: 1, SAHA
|
Growth inhibition of human MDA-MB-231 cells after 96 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
MDA-MB-231
|
GI50 |
2 μM
Compound: 1, SAHA, Zolinza, Vorinostat
|
Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition by SRB assay
|
[PMID: 23163332]
|
|
MDA-MB-231
|
GI50 |
|
Growth inhibition of human MDA-MB-231 cells by SRB assay
Growth inhibition of human MDA-MB-231 cells by SRB assay
|
[PMID: 17904843]
|
|
MDA-MB-231
|
GI50 |
|
Growth inhibition of human MDA-MB-231 cells after 5 days by sulforhodamine B assay
Growth inhibition of human MDA-MB-231 cells after 5 days by sulforhodamine B assay
|
[PMID: 25811792]
|
|
MDA-MB-231
|
GI50 |
|
Growth inhibition of human MDA-MB-231 cells measured after 5 days by sulforhodamine-B assay
Growth inhibition of human MDA-MB-231 cells measured after 5 days by sulforhodamine-B assay
|
[PMID: 28011426]
|
|
MDA-MB-231
|
GI50 |
2.32 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
MDA-MB-231
|
GI50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
MDA-MB-231
|
GI50 |
2.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTS assay
Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
MDA-MB-231
|
GI50 |
2.67 μM
Compound: 1; SAHA
|
Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28395150]
|
|
MDA-MB-231
|
GI50 |
2.73 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
|
[PMID: 36262394]
|
|
MDA-MB-231
|
IC50 |
0.16 μM
Compound: SAHA, Vorinostat
|
Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 24095016]
|
|
MDA-MB-231
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
MDA-MB-231
|
IC50 |
0.201 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by resazurin dye based fluorescence assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by resazurin dye based fluorescence assay
|
[PMID: 29456804]
|
|
MDA-MB-231
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 5 days by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 5 days by MTT assay
|
[PMID: 28601509]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs in presence of fedratinib by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs in presence of fedratinib by MTT assay
|
[PMID: 37796543]
|
|
MDA-MB-231
|
IC50 |
0.61 μM
Compound: 6; SAHA
|
Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured after 7 days by CellTiter-Glo luminescence assay
|
[PMID: 30078609]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
|
[PMID: 34237620]
|
|
MDA-MB-231
|
IC50 |
0.61 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in cisplatin resistant human MDA-MB-231 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in cisplatin resistant human MDA-MB-231 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
MDA-MB-231
|
IC50 |
0.61 μM
Compound: SAHA, vorinostat
|
Inhibition of HDAC in cisplatin sensitive human MDA-MB-231 cells after 18 hrs by fluorescence assay
Inhibition of HDAC in cisplatin sensitive human MDA-MB-231 cells after 18 hrs by fluorescence assay
|
[PMID: 23252603]
|
|
MDA-MB-231
|
IC50 |
0.61 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells
Antiproliferative activity against human MDA-MB-231 cells
|
[PMID: 37875056]
|
|
MDA-MB-231
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
MDA-MB-231
|
IC50 |
0.96 μM
Compound: 6; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
Antiproliferative activity against human MDA-MB-231 cells treated for 48 hrs followed by refreshed every 96 hrs measured on day 10 by Lowry assay
|
[PMID: 26613635]
|
|
MDA-MB-231
|
IC50 |
0.97 μM
Compound: 6; SAHA
|
Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
Cytotoxicity against ER negative human MDA-MB-231 cells treated every 2 days for 4 days measured post last dose by CellTiter-Glo luminescence assay
|
[PMID: 30078609]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
|
[PMID: 33586434]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
10.1039/C4MD00203B
|
|
MDA-MB-231
|
IC50 |
1.18 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 21733698]
|
|
MDA-MB-231
|
IC50 |
1.19 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 27541357]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 28953386]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells
Antiproliferative activity against human MDA-MB-231 cells
|
[PMID: 29945795]
|
|
MDA-MB-231
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
MDA-MB-231
|
IC50 |
|
Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
Growth inhibition of human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 24702857]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
|
[PMID: 23906422]
|
|
MDA-MB-231
|
IC50 |
1.31 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 21476600]
|
|
MDA-MB-231
|
IC50 |
1.35 μM
Compound: Vorinostat
|
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
MDA-MB-231
|
IC50 |
1.45 μM
Compound: 1; SAHA
|
Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
|
[PMID: 33077264]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 30243158]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells measured after 48 hrs by MTT assay
|
[PMID: 35041998]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs in presence of CF53 by CCK-8 assay
|
[PMID: 36622852]
|
|
MDA-MB-231
|
IC50 |
1.66 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against cisplatin sensitive human MDA-MB-231 cells after 72 hrs by MTT assay
Cytotoxicity against cisplatin sensitive human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
MDA-MB-231
|
IC50 |
1.72 μM
Compound: SA, SAHA
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 26907204]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 34043359]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by SRB assay
|
10.1039/C4MD00211C
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells incubated for 72 hrs by MTT assay
|
[PMID: 38452727]
|
|
MDA-MB-231
|
IC50 |
1.91 μM
Compound: SAHA, Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 21924799]
|
|
MDA-MB-231
|
IC50 |
|
Anti-proliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Anti-proliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 28947154]
|
|
MDA-MB-231
|
IC50 |
1.98 μM
Compound: XII; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
MDA-MB-231
|
IC50 |
|
Inhibition of MDA-MB-231 cell proliferation (mean of two experiments)
Inhibition of MDA-MB-231 cell proliferation (mean of two experiments)
|
[PMID: 17095213]
|
|
MDA-MB-231
|
IC50 |
|
Inhibition of MDA-MB-231 cell proliferation (mean of two experiments)
Inhibition of MDA-MB-231 cell proliferation (mean of two experiments)
|
[PMID: 17107790]
|
|
MDA-MB-231
|
IC50 |
13.48 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
MDA-MB-231
|
IC50 |
1480 nM
Compound: 1; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
MDA-MB-231
|
IC50 |
|
Growth inhibition of human MDA-MB-231 cells
Growth inhibition of human MDA-MB-231 cells
|
[PMID: 20850971]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26149591]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after hrs by ATP content assay
Antiproliferative activity against human MDA-MB-231 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
|
[PMID: 30245394]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231cells
Cytotoxicity against human MDA-MB-231cells
|
[PMID: 17691763]
|
|
MDA-MB-231
|
IC50 |
|
Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
|
[PMID: 36244186]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 25311567]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells measured after 72 hrs by MTT assay
|
[PMID: 34847495]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 24 hrs by CCK-8 assay
|
[PMID: 36622852]
|
|
MDA-MB-231
|
IC50 |
2.59 μM
Compound: Vorinostat
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
MDA-MB-231
|
IC50 |
2.69 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against cisplatin resistant human MDA-MB-231 cells after 72 hrs by MTT assay
Cytotoxicity against cisplatin resistant human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 23252603]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter blue-reagent based assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by CellTiter blue-reagent based assay
|
[PMID: 30645113]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by Celltiter-glo assay
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by Celltiter-glo assay
|
[PMID: 38141287]
|
|
MDA-MB-231
|
IC50 |
2.92 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 7 days
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 7 days
|
[PMID: 35643262]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
MDA-MB-231
|
IC50 |
3.07 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36153841]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 24 to 48 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 24 to 48 hrs by CCK-8 assay
|
[PMID: 39145486]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells harboring wild type BRCA1 and wild BRCA2 assessed as reduction in cell viability
Cytotoxicity against human MDA-MB-231 cells harboring wild type BRCA1 and wild BRCA2 assessed as reduction in cell viability
|
[PMID: 36053318]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity in human MDA-MB-231 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
Antiproliferative activity in human MDA-MB-231 cells assessed as inhibition of cell viability after 72 hrs by MTS assay
|
[PMID: 32061484]
|
|
MDA-MB-231
|
IC50 |
3.4 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against ERalpha and ERbeta-deficient human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against ERalpha and ERbeta-deficient human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23786452]
|
|
MDA-MB-231
|
IC50 |
|
Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation
Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation
|
[PMID: 35944852]
|
|
MDA-MB-231
|
IC50 |
3.52 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 5 days by beckman coulter counting method
|
[PMID: 33261898]
|
|
MDA-MB-231
|
IC50 |
3.52 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 74 hrs by SRB assay
|
[PMID: 35255412]
|
|
MDA-MB-231
|
IC50 |
3.96 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
|
[PMID: 25874326]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells up to 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells up to 72 hrs by MTT assay
|
[PMID: 27541357]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 28757101]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
MDA-MB-231
|
IC50 |
4.61 μM
Compound: 1, SAHA
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 24525003]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 26216016]
|
|
MDA-MB-231
|
IC50 |
4.66 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by SRB assay
|
[PMID: 32180916]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
|
[PMID: 29954683]
|
|
MDA-MB-231
|
IC50 |
5.52 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 35477142]
|
|
MDA-MB-231
|
IC50 |
|
Inhibition of human MDA-MB-231 cell proliferation after 48 hrs by MTT assay
Inhibition of human MDA-MB-231 cell proliferation after 48 hrs by MTT assay
|
[PMID: 23493449]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human MDA-MB-231 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth measured after 2 days by CCK8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth measured after 2 days by CCK8 assay
|
[PMID: 34610548]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
|
[PMID: 27665180]
|
|
MDA-MB-231
|
IC50 |
|
Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 25815139]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells measured after 24 hrs by MTT assay
|
[PMID: 32791401]
|
|
MDA-MB-231
|
IC50 |
8.25 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
|
[PMID: 34656899]
|
|
MDA-MB-231
|
IC50 |
|
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37796543]
|
|
MDA-MB-231
|
IC50 |
> 100 μM
Compound: 1; SAHA
|
Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 28885834]
|
|
MDA-MB-231
|
IC50 |
> 411 nM
Compound: Vorinostat
|
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
MDA-MB-238
|
IC50 |
4.92 μM
Compound: 1; SAHA
|
Anticancer activity against human MDA-MB-238 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
Anticancer activity against human MDA-MB-238 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 staining based microplate reader analysis
|
[PMID: 36215854]
|
|
MDA-MB-435
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MDA-MB-435 cells after 72 hrs by MTS assay
Growth inhibition of human MDA-MB-435 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
MDA-MB-435
|
GI50 |
0.88 μM
Compound: 1, SAHA
|
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24119555]
|
|
MDA-MB-435
|
GI50 |
|
Antiproliferative activity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
Antiproliferative activity against human MDA-MB-435 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 25800646]
|
|
MDA-MB-435
|
IC50 |
1.9 μM
Compound: 3 (SAHA)
|
Antiproliferative activity against MDA-435 (human breast carcinoma) cell line.
Antiproliferative activity against MDA-435 (human breast carcinoma) cell line.
|
[PMID: 12749893]
|
|
MDA-MB-435
|
IC50 |
1900 nM
Compound: 1 (SAHA)
|
Inhibitory concentration against MDA-435 cells proliferation
Inhibitory concentration against MDA-435 cells proliferation
|
[PMID: 14613312]
|
|
MDA-MB-436
|
IC50 |
|
Antiproliferative activity against human MDA-MB-436 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human MDA-MB-436 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
MDA-MB-453
|
IC50 |
0.37 μM
Compound: 5; SAHA
|
Antiproliferative activity against human MDA-MB-453 cells after 96 hrs by MTT assay
Antiproliferative activity against human MDA-MB-453 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
MDA-MB-468
|
GI50 |
0.63 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MDA-MB-468 cells after 72 hrs by MTS assay
Growth inhibition of human MDA-MB-468 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
MDA-MB-468
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
MDA-MB-468
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
MDA-MB-468
|
IC50 |
|
Antiproliferative activity against human MDA-MB-468 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-468 cells incubated for 72 hrs by MTT assay
|
[PMID: 32961382]
|
|
MDA-MB-468
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human MDA-MB-468 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human MDA-MB-468 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
MDA-MB-468
|
IC50 |
|
Cytotoxicity against human MDA-MB-468 cells
Cytotoxicity against human MDA-MB-468 cells
|
[PMID: 17691763]
|
|
MDA-MB-468
|
IC50 |
|
Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
MDA-MB-468
|
IC50 |
|
Cytotoxicity against human MDA-MB-468 cells harboring wild type BRCA1 and BRCA2 mutant reduction in assessed as cell viability
Cytotoxicity against human MDA-MB-468 cells harboring wild type BRCA1 and BRCA2 mutant reduction in assessed as cell viability
|
[PMID: 36053318]
|
|
MDA-MB-468
|
IC50 |
2.69 μM
Compound: Vorinostat
|
Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
MDA-MB-468
|
IC50 |
|
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
Antiproliferative activity against human MDA-MB-468 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
|
[PMID: 33586434]
|
|
MDA-MB-468
|
IC50 |
|
Anticancer activity against human MDA-MB-468 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
Anticancer activity against human MDA-MB-468 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
|
[PMID: 36244186]
|
|
MDA-MB-468
|
IC50 |
|
Antiproliferative activity against human MDA-MB-468 cells
Antiproliferative activity against human MDA-MB-468 cells
|
[PMID: 20143778]
|
|
MEF
|
IC50 |
|
Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay
Cytotoxicity against mouse MEF cells after 72 hrs by MTT assay
|
[PMID: 23570542]
|
|
MG-63
|
GI50 |
> 10 μM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human MG63 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human MG63 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
|
[PMID: 33957387]
|
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay
|
[PMID: 36996717]
|
|
MGC-803
|
IC50 |
1.7 μM
Compound: SAHA; 112
|
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation by CCK-8 assay
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation by CCK-8 assay
|
[PMID: 31881454]
|
|
MGC-803
|
IC50 |
1.7 μM
Compound: Vorinostat
|
Cytotoxicity against human MGC803 cells assessed as reduction in cell viability
Cytotoxicity against human MGC803 cells assessed as reduction in cell viability
|
[PMID: 30660827]
|
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition after 72 hrs by SRB assay
|
[PMID: 34454126]
|
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
|
[PMID: 37086699]
|
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
MGC-803
|
IC50 |
8.67 μM
Compound: Vorinostat
|
Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
|
[PMID: 33831778]
|
|
MGC-803
|
IC50 |
|
Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
|
[PMID: 28987602]
|
|
MGC-803
|
IC50 |
|
Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34628244]
|
|
MIA PaCa-2
|
GI50 |
3500 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
MIA PaCa-2
|
GI50 |
|
Antiproliferative activity against human MIAPaCa2 cells after 48 hrs by MTT assay
Antiproliferative activity against human MIAPaCa2 cells after 48 hrs by MTT assay
|
[PMID: 24999749]
|
|
MIA PaCa-2
|
IC50 |
|
Antiproliferative activity against human MiaPaca2 cells after 72 hrs by MTT assay
Antiproliferative activity against human MiaPaca2 cells after 72 hrs by MTT assay
|
[PMID: 18642892]
|
|
MIA PaCa-2
|
IC50 |
|
Antiproliferative activity against human MIAPaCa2 cells by MTT assay
Antiproliferative activity against human MIAPaCa2 cells by MTT assay
|
[PMID: 19419863]
|
|
MIA PaCa-2
|
IC50 |
1.1 μM
Compound: 1a, SAHA
|
Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTS assay
Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTS assay
|
[PMID: 20055418]
|
|
MIA PaCa-2
|
IC50 |
|
Cytotoxicity against human Mia Paca2 cells after 72 hrs by MTT assay
Cytotoxicity against human Mia Paca2 cells after 72 hrs by MTT assay
|
[PMID: 18494463]
|
|
MIA PaCa-2
|
IC50 |
|
Cytotoxicity against human MIAPaCa2 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
MIA PaCa-2
|
IC50 |
|
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
MKN-45
|
GI50 |
7.3 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human MKN45 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human MKN45 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
MKN-45
|
IC50 |
1.25 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human MKN45 cells by MTT assay
Cytotoxicity against human MKN45 cells by MTT assay
|
[PMID: 24766560]
|
|
MKN-45
|
IC50 |
|
Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
MM1.S
|
IC50 |
|
Antiproliferative activity against human MM.1S cells assessed as inhibition of cell growth incubated for 72 hrs by microplate photometer analysis
Antiproliferative activity against human MM.1S cells assessed as inhibition of cell growth incubated for 72 hrs by microplate photometer analysis
|
[PMID: 38116436]
|
|
MM1.S
|
IC50 |
|
Antiproliferative activity against human MM1S cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
Antiproliferative activity against human MM1S cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
|
[PMID: 26890114]
|
|
MM1.S
|
IC50 |
|
Cytotoxicity against human MM1.S cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
Cytotoxicity against human MM1.S cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
|
[PMID: 35119267]
|
|
MM1.S
|
IC50 |
|
Antiproliferative activity against human MM1S cells after 72 hrs by MTS assay
Antiproliferative activity against human MM1S cells after 72 hrs by MTS assay
|
[PMID: 29795767]
|
|
MM1.S
|
IC50 |
|
Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
|
[PMID: 30629434]
|
|
MM1.S
|
IC50 |
|
Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
Antiproliferative activity against human MM1S cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
MM473
|
IC50 |
|
Antiproliferative activity against human MM473 cells at 10 uM after 72 hrs by MTT assay relative to control
Antiproliferative activity against human MM473 cells at 10 uM after 72 hrs by MTT assay relative to control
|
[PMID: 29150335]
|
|
MM473
|
IC50 |
|
Antiproliferative activity against human MM473 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human MM473 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
MM96L
|
EC50 |
|
Antiproliferative activity against human MM96L cells assessed as cell growth inhibition by SRB assay
Antiproliferative activity against human MM96L cells assessed as cell growth inhibition by SRB assay
|
[PMID: 34591488]
|
|
MOLM-13
|
EC50 |
|
Growth inhibition of human MOLM13 cells after 44 hrs by MTT assay
Growth inhibition of human MOLM13 cells after 44 hrs by MTT assay
|
[PMID: 28337317]
|
|
MOLM-13
|
IC50 |
0.345 μM
Compound: 1; SAHA
|
Cytotoxicity against human MOLM13 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
Cytotoxicity against human MOLM13 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
|
[PMID: 31938464]
|
|
MOLM-13
|
IC50 |
|
Antiproliferative activity against human MOLM13 cells harboring wild type p53/FLT3-ITD mutant after 72 hrs by MTT assay
Antiproliferative activity against human MOLM13 cells harboring wild type p53/FLT3-ITD mutant after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
MOLM-14
|
EC50 |
0.54 μM
Compound: 3; SAHA
|
Antiproliferative activity against human MOLM14 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human MOLM14 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 31627059]
|
|
MOLT-4
|
GI50 |
0.4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MOLT4 cells after 72 hrs by MTS assay
Growth inhibition of human MOLT4 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
MOLT-4
|
GI50 |
0.68 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human MOLT4 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human MOLT4 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
MOLT-4
|
GI50 |
|
Growth inhibition of human MOLT-4 cells measured after 24 hrs by MTT assay
Growth inhibition of human MOLT-4 cells measured after 24 hrs by MTT assay
|
[PMID: 37429084]
|
|
MOLT-4
|
GI50 |
|
Antiproliferative activity against human MOLT4 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MOLT4 cells after 72 hrs by CCK8 assay
|
[PMID: 26331334]
|
|
MOLT-4
|
GI50 |
670 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human MOLT4 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human MOLT4 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
MOLT-4
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
|
[PMID: 28336407]
|
|
MOLT-4
|
IC50 |
0.33 μM
Compound: Vorinostat
|
Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 38107170]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT4 cells incubated for 24 hrs by CCK8 assay
Antiproliferative activity against human MOLT4 cells incubated for 24 hrs by CCK8 assay
|
[PMID: 32247729]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT4 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 30901208]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
|
[PMID: 29533873]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT-4 cells after 48 hrs by CCK-8 assay
Antiproliferative activity against human MOLT-4 cells after 48 hrs by CCK-8 assay
|
[PMID: 35939996]
|
|
MOLT-4
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human MOLT-4 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human MOLT-4 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
MOLT-4
|
IC50 |
0.52 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human MOLT-4 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human MOLT-4 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
MOLT-4
|
IC50 |
0.56 μM
Compound: Vorinostat
|
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
|
[PMID: 28371677]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
|
[PMID: 37086699]
|
|
MOLT-4
|
IC50 |
|
Cytotoxicity against human MOLT4 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human MOLT4 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
MOLT-4
|
IC50 |
|
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells after 48 hrs by MTT assay
|
[PMID: 29500131]
|
|
MOLT-4
|
IC50 |
3.09 μM
Compound: XII; SAHA
|
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human MOLT-4 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
MRC5
|
IC50 |
|
Anti-proliferative activity against human MRC5 cells after 48 hrs by MTT assay
Anti-proliferative activity against human MRC5 cells after 48 hrs by MTT assay
|
[PMID: 28947154]
|
|
MV4-11
|
EC50 |
0.53 μM
Compound: Vor; SAHA
|
Induction of cell death in human MV4-11 cells measured at 48 hrs by fluorescence based microplate reader analysis
Induction of cell death in human MV4-11 cells measured at 48 hrs by fluorescence based microplate reader analysis
|
[PMID: 29360358]
|
|
MV4-11
|
EC50 |
0.9 μM
Compound: Vor; SAHA
|
Induction of apoptosis in human MV4-11 cells assessed as increase in caspase 3/7 activity measured at 24 hrs in presence of Z-DEVD-R110 or (Z-Asp-Glu-Val-Asp)2-rhodamine110 by fluorescence based microplate reader analysis
Induction of apoptosis in human MV4-11 cells assessed as increase in caspase 3/7 activity measured at 24 hrs in presence of Z-DEVD-R110 or (Z-Asp-Glu-Val-Asp)2-rhodamine110 by fluorescence based microplate reader analysis
|
[PMID: 29360358]
|
|
MV4-11
|
EC50 |
418.1 nM
Compound: SAHA; Vor
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Blue dye based spectrophotometric analysis
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Blue dye based spectrophotometric analysis
|
[PMID: 32321249]
|
|
MV4-11
|
EC50 |
< 30 nM
Compound: Vorinostat
|
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 48 hrs by Cell-titer-blue cell viability assay
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 48 hrs by Cell-titer-blue cell viability assay
|
[PMID: 27754681]
|
|
MV4-11
|
GI50 |
|
Antiproliferative activity against human MV4-11 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
Antiproliferative activity against human MV4-11 cells assessed as growth inhibition after 48 hrs by CellTiter-Glo assay
|
[PMID: 25800646]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs in presence of SHP099 by CCK-8 assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs in presence of SHP099 by CCK-8 assay
|
[PMID: 36097406]
|
|
MV4-11
|
IC50 |
0.26 μM
Compound: 10; SAHA
|
Antiproliferative activity against human MV4-11 cells assessed as cell viability after 72 hrs by CCK8 assay
Antiproliferative activity against human MV4-11 cells assessed as cell viability after 72 hrs by CCK8 assay
|
[PMID: 33077265]
|
|
MV4-11
|
IC50 |
|
Cytotoxicity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
Cytotoxicity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs measured by spectrophotometer analysis
|
[PMID: 35119267]
|
|
MV4-11
|
IC50 |
0.31 μM
Compound: 1; SAHA
|
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer blue assay
|
[PMID: 31938464]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
|
[PMID: 37086699]
|
|
MV4-11
|
IC50 |
|
Cytotoxicity against human MV4-11 cells assessed as cell viability incubated for 72 hrs by Cell titer-blue assay
Cytotoxicity against human MV4-11 cells assessed as cell viability incubated for 72 hrs by Cell titer-blue assay
|
[PMID: 34101461]
|
|
MV4-11
|
IC50 |
|
Inhibition of cell viability in human MV4-11 cells incubated for 4 days in presence of GSK5032 by CCK8 assay
Inhibition of cell viability in human MV4-11 cells incubated for 4 days in presence of GSK5032 by CCK8 assay
|
[PMID: 39264152]
|
|
MV4-11
|
IC50 |
0.421 μM
Compound: Vorinostat
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by CellTiterGlo assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by CellTiterGlo assay
|
[PMID: 37659198]
|
|
MV4-11
|
IC50 |
0.43 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
|
[PMID: 29360358]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells incubated for 48 hrs by resazurin based microplate reader analysis
Antiproliferative activity against human MV4-11 cells incubated for 48 hrs by resazurin based microplate reader analysis
|
[PMID: 37647727]
|
|
MV4-11
|
IC50 |
0.493 μM
Compound: Vorinostat
|
Cytotoxicity against human MV4-11 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
Cytotoxicity against human MV4-11 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay
|
[PMID: 37875056]
|
|
MV4-11
|
IC50 |
|
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MV4-11 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 30034592]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36097406]
|
|
MV4-11
|
IC50 |
0.51 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 3 days in presence of atamparib by celltiter-glo luminescent assay
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 3 days in presence of atamparib by celltiter-glo luminescent assay
|
[PMID: 38456618]
|
|
MV4-11
|
IC50 |
0.55 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo luminescent assay
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo luminescent assay
|
[PMID: 38456618]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell proliferation incubated for 72 hrs by CCK8 assay
|
[PMID: 36272186]
|
|
MV4-11
|
IC50 |
|
Cytotoxicity against human MV411 cells
Cytotoxicity against human MV411 cells
|
[PMID: 26005563]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells incubated for 96 hrs by CCK8 assay
Antiproliferative activity against human MV4-11 cells incubated for 96 hrs by CCK8 assay
|
[PMID: 39264152]
|
|
MV4-11
|
IC50 |
|
Inhibition of cell viability in human MV4-11 cells incubated for 4 days by CCK8 assay
Inhibition of cell viability in human MV4-11 cells incubated for 4 days by CCK8 assay
|
[PMID: 39264152]
|
|
MV4-11
|
IC50 |
0.72 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by Alamar blue assay
|
[PMID: 27142751]
|
|
MV4-11
|
IC50 |
0.85 μM
Compound: 1; SAHA
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36153841]
|
|
MV4-11
|
IC50 |
0.88 μM
Compound: SAHA; 6
|
Antiproliferative activity against human MV4-11 cells incubated for 72 hrs by celltiter-glo luminescent assay
Antiproliferative activity against human MV4-11 cells incubated for 72 hrs by celltiter-glo luminescent assay
|
[PMID: 39178382]
|
|
MV4-11
|
IC50 |
0.98 μM
Compound: 5; SAHA
|
Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
|
[PMID: 28765013]
|
|
MV4-11
|
IC50 |
|
Cytotoxicity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
|
[PMID: 30629434]
|
|
MV4-11
|
IC50 |
|
Cytotoxicity against human MV4-11 cells assessed as growth inhibition after 24 hrs by MTT assay
Cytotoxicity against human MV4-11 cells assessed as growth inhibition after 24 hrs by MTT assay
|
[PMID: 27186676]
|
|
MV4-11
|
IC50 |
|
Growth inhibition of human MV4-11 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
Growth inhibition of human MV4-11 cells assessed as ATP level after 72 hrs by CellTiterGlo assay
|
10.1039/C3MD00285C
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells
Antiproliferative activity against human MV4-11 cells
|
[PMID: 35580726]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based assay
Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 48 hrs by resazurin staining based assay
|
[PMID: 39047608]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
Antiproliferative activity against human MV4-11 cells after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
MV4-11
|
IC50 |
|
Antiproliferative activity against human MV4-11 cells harboring wild type p53 assessed as inhibition of cell growth incubated for 48 hrs by resazurin dye based fluorescence analysis
Antiproliferative activity against human MV4-11 cells harboring wild type p53 assessed as inhibition of cell growth incubated for 48 hrs by resazurin dye based fluorescence analysis
|
[PMID: 38224650]
|
|
MV4-11
|
IC50 |
8.44 μM
Compound: 4; SAHA
|
Antiproliferative activity against human MV4-11 cells harboring FLT3-ITD mutant assessed as reduction in cell viability
Antiproliferative activity against human MV4-11 cells harboring FLT3-ITD mutant assessed as reduction in cell viability
|
[PMID: 34314844]
|
|
MV4-11
|
IC50 |
|
Cytotoxicity against human MV4-11 cells after 72 hrs by MTT assay
Cytotoxicity against human MV4-11 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
Malme-3M
|
GI50 |
0.32 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human MALME-3M cells after 72 hrs by MTS assay
Growth inhibition of human MALME-3M cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
Malme-3M
|
GI50 |
0.37 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human MALME-3M cells after 48 hrs by SRB assay
Cytotoxicity against human MALME-3M cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
N2a
|
IC50 |
|
Cytotoxicity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 24 hrs by Cell Titer-Glo 2.0 Luminescent cell assay
Cytotoxicity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 24 hrs by Cell Titer-Glo 2.0 Luminescent cell assay
|
[PMID: 33845233]
|
|
NALM-6
|
IC50 |
|
Antiproliferative activity against human NALM-6 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human NALM-6 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
|
[PMID: 36395680]
|
|
NAMALVA
|
IC50 |
0.11 μM
Compound: 1; SAHA
|
Cytotoxicity against human NAMALVA cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human NAMALVA cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 33668008]
|
|
NAMALVA
|
IC50 |
0.11 μM
Compound: Vorinostat
|
Cytotoxicity against human NAMALVA cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
Cytotoxicity against human NAMALVA cells assessed as cell growth inhibition incubated for 24 to 72 hrs by MTT assay
|
[PMID: 37989057]
|
|
NB-4
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against human NB4 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against human NB4 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
NB-4
|
IC50 |
0.6 μM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human NB4 cells after 48 hrs
Antiproliferative activity against human NB4 cells after 48 hrs
|
[PMID: 18723349]
|
|
NB-4
|
IC50 |
|
Antiproliferative activity against human NB4 cells after 72 hrs
Antiproliferative activity against human NB4 cells after 72 hrs
|
[PMID: 19084294]
|
|
NB-4
|
IC50 |
|
Growth inhibition of human NB4 cells after 72 hrs
Growth inhibition of human NB4 cells after 72 hrs
|
[PMID: 26376355]
|
|
NB-4
|
IC50 |
0.7 μM
Compound: SAHA, vorinostat
|
Growth inhibition of human NB4 cells by SRB assay
Growth inhibition of human NB4 cells by SRB assay
|
[PMID: 17892933]
|
|
NB-4
|
IC50 |
|
Antiproliferative activity against human NB4 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human NB4 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
NB-4
|
IC50 |
0.98 μM
Compound: SAHA, Vorinostat
|
Induction of apoptosis in human NB4 cells after 48 hrs by Annexin V test
Induction of apoptosis in human NB4 cells after 48 hrs by Annexin V test
|
[PMID: 23792316]
|
|
NB-4
|
IC50 |
|
Antiproliferative activity against human NB-4 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human NB-4 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
NB-4
|
IC50 |
1.52 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human NB4 cells after 48 hrs by MTT assay
Cytotoxicity against human NB4 cells after 48 hrs by MTT assay
|
[PMID: 21476600]
|
|
NB-4
|
IC50 |
|
Antiproliferative activity against human NB4 cells after 72 hrs by MTT assay
Antiproliferative activity against human NB4 cells after 72 hrs by MTT assay
|
[PMID: 29150335]
|
|
NB-4
|
IC50 |
880 nM
Compound: Vorinostat
|
Cytotoxicity against human NB-4 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human NB-4 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
NB1
|
IC50 |
2.71 μM
Compound: Vorinostat
|
Antiproliferative activity against human NB-1 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
Antiproliferative activity against human NB-1 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
|
[PMID: 31391882]
|
|
NCI-H1299
|
IC50 |
|
Cytotoxicity against human NCI-H1299 by SRB assay
Cytotoxicity against human NCI-H1299 by SRB assay
|
[PMID: 20855208]
|
|
NCI-H1299
|
IC50 |
3.46 μM
Compound: Vorinostat
|
Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
NCI-H1299
|
IC50 |
4.92 μM
Compound: 1; SAHA
|
Antiproliferative activity against human NCI-H1299 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human NCI-H1299 cells after 72 hrs by CCK8 assay
|
[PMID: 30045621]
|
|
NCI-H1299
|
IC50 |
|
Antiproliferative activity against human NCI-H1299 cells after 96 hrs by MTT assay
Antiproliferative activity against human NCI-H1299 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
NCI-H1299
|
IC50 |
5.53 μM
Compound: Vorinostat
|
Cytotoxicity against human NCI-H1299 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human NCI-H1299 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
NCI-H1299
|
IC50 |
|
Antiproliferative activity against human H1299 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human H1299 cells incubated for 48 hrs by MTT assay
|
[PMID: 30851694]
|
|
NCI-H1299
|
IC50 |
7.24 μM
Compound: 3, SAHA
|
Antiproliferative activity against H1299 cells
Antiproliferative activity against H1299 cells
|
[PMID: 16904890]
|
|
NCI-H1299
|
IC50 |
7240 nM
Compound: SAHA (1)
|
Inhibitory activity against H1299 human lung carcinoma cell growth
Inhibitory activity against H1299 human lung carcinoma cell growth
|
[PMID: 14521422]
|
|
NCI-H1299
|
IC50 |
8200 nM
Compound: 1, SAHA
|
Antiproliferative activity against human H1299 cells
Antiproliferative activity against human H1299 cells
|
[PMID: 21650221]
|
|
NCI-H1373
|
IC50 |
0.13 μM
Compound: 1; SAHA
|
Antiproliferative activity against human NCI-H1373 cells assessed as inhibition of cell growth incubated for 6 days in presence of atamparib by celltiter-glo luminescent assay
Antiproliferative activity against human NCI-H1373 cells assessed as inhibition of cell growth incubated for 6 days in presence of atamparib by celltiter-glo luminescent assay
|
[PMID: 38456618]
|
|
NCI-H1373
|
IC50 |
1.46 μM
Compound: 1; SAHA
|
Antiproliferative activity against human NCI-H1373 cells assessed as inhibition of cell growth incubated for 6 days by celltiter-glo luminescent assay
Antiproliferative activity against human NCI-H1373 cells assessed as inhibition of cell growth incubated for 6 days by celltiter-glo luminescent assay
|
[PMID: 38456618]
|
|
NCI-H157
|
IC50 |
1.33 μM
Compound: Vorinostat
|
Antiproliferative activity against human NCI-H157 cells
Antiproliferative activity against human NCI-H157 cells
|
[PMID: 37875056]
|
|
NCI-H1581
|
IC50 |
|
Cytotoxicity against human NCI-1581 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-1581 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
NCI-H1650
|
IC50 |
|
Antiproliferative activity against human NCI-H1650 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human NCI-H1650 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
NCI-H1975
|
GI50 |
0.98 μM
Compound: 1; SAHA
|
Growth inhibition of human NCI-H1975 cells incubated for 48 hrs by SRB assay
Growth inhibition of human NCI-H1975 cells incubated for 48 hrs by SRB assay
|
[PMID: 32058238]
|
|
NCI-H1975
|
GI50 |
1.41 μM
Compound: SAHA; 1
|
Antiproliferative activity against human NCI-H1975 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H1975 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 29567459]
|
|
NCI-H1975
|
GI50 |
2.61 μM
Compound: 1; SAHA
|
Antiproliferative activity against human NCI-H1975 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H1975 cells assessed as cell growth inhibition after 48 hrs by sulforhodamine B assay
|
[PMID: 31655430]
|
|
NCI-H1975
|
IC50 |
|
Cytotoxicity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 48 hrs by Celltiter-glo assay
Cytotoxicity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 48 hrs by Celltiter-glo assay
|
[PMID: 38141287]
|
|
NCI-H1975
|
IC50 |
|
Antiproliferative activity against human NCI-H1975 expressing EGFR T790M/L858R mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H1975 expressing EGFR T790M/L858R mutant assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 27769671]
|
|
NCI-H1975
|
IC50 |
2.04 μM
Compound: Vorinostat
|
Antiproliferative activity against human NCI-H1975 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H1975 cells incubated for 72 hrs by MTT assay
|
[PMID: 33493830]
|
|
NCI-H1975
|
IC50 |
|
Cytotoxicity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
NCI-H2122
|
IC50 |
|
Antiproliferative activity against human NCI-H2122 cells
Antiproliferative activity against human NCI-H2122 cells
|
[PMID: 20143778]
|
|
NCI-H2126
|
IC50 |
|
Cytotoxicity against human NCI-H2126 by SRB assay
Cytotoxicity against human NCI-H2126 by SRB assay
|
[PMID: 20855208]
|
|
NCI-H226
|
EC50 |
|
Inhibition of human NCI-H226 cells
Inhibition of human NCI-H226 cells
|
[PMID: 18247554]
|
|
NCI-H226
|
EC50 |
2.6 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human NCI-H226 cells
Effective Concentration of compound to inhibit the growth of human NCI-H226 cells
|
[PMID: 15715470]
|
|
NCI-H226
|
GI50 |
4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human NCI-H226 cells after 72 hrs by MTS assay
Growth inhibition of human NCI-H226 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
NCI-H226
|
IC50 |
|
Cytotoxicity against human NCI-H226 by SRB assay
Cytotoxicity against human NCI-H226 by SRB assay
|
[PMID: 20855208]
|
|
NCI-H226
|
IC50 |
|
Antiproliferative activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
NCI-H23
|
GI50 |
0.92 μM
Compound: 1, SAHA
|
Growth inhibition of NCI-H23 cells by SRB assay
Growth inhibition of NCI-H23 cells by SRB assay
|
[PMID: 17477518]
|
|
NCI-H23
|
GI50 |
0.92 μM
Compound: 2, SAHA
|
Antiproliferative activity against human NCI-H23 cells by SRB assay
Antiproliferative activity against human NCI-H23 cells by SRB assay
|
[PMID: 16723227]
|
|
NCI-H23
|
GI50 |
1 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human NCI-H23 cells after 72 hrs by MTS assay
Growth inhibition of human NCI-H23 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
NCI-H23
|
GI50 |
|
Growth inhibition of human NCI-H23 cells after 21 hrs by MTT assay
Growth inhibition of human NCI-H23 cells after 21 hrs by MTT assay
|
[PMID: 17662606]
|
|
NCI-H23
|
GI50 |
2 μM
Compound: SAHA; NSC759852
|
Cytotoxicity against human NCI-H23 cells assessed as cell growth inhibition at 10 uM incubated for 24 hrs by MTT assay
Cytotoxicity against human NCI-H23 cells assessed as cell growth inhibition at 10 uM incubated for 24 hrs by MTT assay
|
[PMID: 36306372]
|
|
NCI-H23
|
GI50 |
2.34 μM
Compound: 1, SAHA
|
Growth inhibition of human NCI-H23 cells
Growth inhibition of human NCI-H23 cells
|
[PMID: 20850971]
|
|
NCI-H23
|
GI50 |
2.34 μM
Compound: 1, SAHA, Zolinza, Vorinostat
|
Cytotoxicity against human NCI-H23 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human NCI-H23 cells assessed as growth inhibition by SRB assay
|
[PMID: 23163332]
|
|
NCI-H23
|
GI50 |
|
Growth inhibition of human NCI-H23 cells after 5 days by sulforhodamine B assay
Growth inhibition of human NCI-H23 cells after 5 days by sulforhodamine B assay
|
[PMID: 25811792]
|
|
NCI-H23
|
GI50 |
|
Growth inhibition of human NCI-H23 cells measured after 5 days by sulforhodamine-B assay
Growth inhibition of human NCI-H23 cells measured after 5 days by sulforhodamine-B assay
|
[PMID: 28011426]
|
|
NCI-H23
|
IC50 |
|
Cytotoxicity against human NCI-H23 by SRB assay
Cytotoxicity against human NCI-H23 by SRB assay
|
[PMID: 20855208]
|
|
NCI-H23
|
IC50 |
1.12 μM
Compound: Vorinostat
|
Antiproliferative activity against human NCI-H23 cells incubated for 72 hrs by colorimetric method
Antiproliferative activity against human NCI-H23 cells incubated for 72 hrs by colorimetric method
|
[PMID: 37875056]
|
|
NCI-H23
|
IC50 |
|
Cytotoxicity against human NCI-H23 cells by colorimetric method
Cytotoxicity against human NCI-H23 cells by colorimetric method
|
[PMID: 32916298]
|
|
NCI-H23
|
IC50 |
1.44 μM
Compound: Vorinostat
|
Antiproliferative activity against human NCI-H23 cells incubated for 48 hrs by colorimetric method
Antiproliferative activity against human NCI-H23 cells incubated for 48 hrs by colorimetric method
|
[PMID: 37875056]
|
|
NCI-H23
|
IC50 |
2.8 μM
Compound: Vorinostat
|
Cytotoxicity against human NCI-H23 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human NCI-H23 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
NCI-H23
|
IC50 |
|
Antiproliferative activity against human NCI-H23 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human NCI-H23 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31546197]
|
|
NCI-H292
|
IC50 |
|
Growth inhibition of human NCI-H292 cells after 72 hrs by MTT assay
Growth inhibition of human NCI-H292 cells after 72 hrs by MTT assay
|
[PMID: 28108250]
|
|
NCI-H292
|
IC50 |
|
Growth inhibition of human NCI-H292 cells in LDL depleted FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
Growth inhibition of human NCI-H292 cells in LDL depleted FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
|
[PMID: 28108250]
|
|
NCI-H292
|
IC50 |
|
Growth inhibition of human NCI-H292 cells in FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
Growth inhibition of human NCI-H292 cells in FBS containing medium after 72 hrs using compound after sonication in presence of LDL by MTT assay
|
[PMID: 28108250]
|
|
NCI-H292
|
IC50 |
|
Growth inhibition of human NCI-H292 cells after 72 hrs in presence of LDL by MTT assay
Growth inhibition of human NCI-H292 cells after 72 hrs in presence of LDL by MTT assay
|
[PMID: 28108250]
|
|
NCI-H322M
|
GI50 |
0.79 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human NCI-H322M cells after 72 hrs by MTS assay
Growth inhibition of human NCI-H322M cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
NCI-H358
|
IC50 |
|
Antiproliferative activity against human NCI-H358 cells after hrs by ATP content assay
Antiproliferative activity against human NCI-H358 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
NCI-H441
|
IC50 |
|
Cytotoxicity against human H441 by SRB assay
Cytotoxicity against human H441 by SRB assay
|
[PMID: 20855208]
|
|
NCI-H446
|
IC50 |
0.34 μM
Compound: 1; SAHA
|
Antiproliferative activity against human NCI-H446 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human NCI-H446 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
NCI-H460
|
GI50 |
0.79 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human NCI-H460 cells after 72 hrs by MTS assay
Growth inhibition of human NCI-H460 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
NCI-H460
|
GI50 |
0.85 μM
Compound: 1, SAHA
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24119555]
|
|
NCI-H460
|
GI50 |
|
Antiproliferative activity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by SRB assay
Antiproliferative activity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 25800646]
|
|
NCI-H460
|
GI50 |
|
Cytotoxicity against human NCI-H460 cells by MTT assay
Cytotoxicity against human NCI-H460 cells by MTT assay
|
[PMID: 23538115]
|
|
NCI-H460
|
GI50 |
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
|
[PMID: 20605448]
|
|
NCI-H460
|
IC50 |
0.425 μM
Compound: 1; SAHA
|
Antiproliferative activity against human NCI-H460 cells after 72 hrs by resazurin dye based fluorescence assay
Antiproliferative activity against human NCI-H460 cells after 72 hrs by resazurin dye based fluorescence assay
|
[PMID: 29456804]
|
|
NCI-H460
|
IC50 |
0.68 μg/mL
Compound: SAHA
|
Cytotoxicity against human NCI-H460 cells
Cytotoxicity against human NCI-H460 cells
|
[PMID: 22036991]
|
|
NCI-H460
|
IC50 |
0.82 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human H460 cells by MTT assay
Cytotoxicity against human H460 cells by MTT assay
|
[PMID: 24766560]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells after 72 hrs by SRB assay
Antiproliferative activity against human NCI-H460 cells after 72 hrs by SRB assay
|
[PMID: 29150335]
|
|
NCI-H460
|
IC50 |
1 μM
Compound: Vorinostat
|
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay
|
[PMID: 30660827]
|
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI H460 cells
Cytotoxicity against human NCI H460 cells
|
[PMID: 17691763]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells after hrs by ATP content assay
Antiproliferative activity against human H460 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
NCI-H460
|
IC50 |
1.7 μM
Compound: SAHA; 112
|
Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell proliferation by CCK-8 assay
Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell proliferation by CCK-8 assay
|
[PMID: 31881454]
|
|
NCI-H460
|
IC50 |
1.7 μM
Compound: Vorinostat
|
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability
|
[PMID: 30660827]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells after 96 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human H460 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
|
[PMID: 31991336]
|
|
NCI-H460
|
IC50 |
2.77 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by SRB assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by SRB assay
|
[PMID: 24185378]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
NCI-H460
|
IC50 |
|
Growth inhibition of human H460 cells after 48 hrs by SRB assay
Growth inhibition of human H460 cells after 48 hrs by SRB assay
|
[PMID: 21073160]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells after 72 hrs
Antiproliferative activity against human H460 cells after 72 hrs
|
[PMID: 19084294]
|
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human H460 cells after 24 hrs by sulforhodamine B assay
Cytotoxicity against human H460 cells after 24 hrs by sulforhodamine B assay
|
[PMID: 19359173]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells assessed as growth inhibition after 72 hrs
Antiproliferative activity against human H460 cells assessed as growth inhibition after 72 hrs
|
[PMID: 24742384]
|
|
NCI-H460
|
IC50 |
|
Growth inhibition of human H460 cells after 72 hrs
Growth inhibition of human H460 cells after 72 hrs
|
[PMID: 26376355]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human H460 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
Antiproliferative activity against human H460 cells assessed as reduction in cell number after 72 hrs by cell counter analysis
|
[PMID: 26890116]
|
|
NCI-H460
|
IC50 |
3.4 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against human H460 cells
Cytotoxicity against human H460 cells
|
[PMID: 24345446]
|
|
NCI-H460
|
IC50 |
3.4 μM
Compound: SAHA, vorinostat
|
Growth inhibition of human H460 cells by SRB assay
Growth inhibition of human H460 cells by SRB assay
|
[PMID: 17892933]
|
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI-H460 by SRB assay
Cytotoxicity against human NCI-H460 by SRB assay
|
[PMID: 20855208]
|
|
NCI-H460
|
IC50 |
3400 nM
Compound: 1, SAHA
|
Cytotoxicity against human NCI-H460 cells
Cytotoxicity against human NCI-H460 cells
|
[PMID: 25563890]
|
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human NCI-H460 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
NCI-H460
|
IC50 |
5.46 μM
Compound: Vorinostat
|
Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
NCI-H460
|
IC50 |
6.29 μM
Compound: Vorinostat
|
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
NCI-H460
|
IC50 |
|
Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
NCI-H460
|
IC50 |
|
Cytotoxicity against human H460 cells after 72 hrs by MTT assay
Cytotoxicity against human H460 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
NCI-H522
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human NCI-H522 cells after 72 hrs by MTS assay
Growth inhibition of human NCI-H522 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
NCI-H522
|
IC50 |
|
Cytotoxicity against human NCI-H522 by SRB assay
Cytotoxicity against human NCI-H522 by SRB assay
|
[PMID: 20855208]
|
|
NCI-H522
|
IC50 |
|
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
|
[PMID: 35984756]
|
|
NCI-H522
|
IC50 |
|
Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
|
[PMID: 36244186]
|
|
NCI-H526
|
GI50 |
0.481 μM
Compound: Vorinostat
|
Antiproliferative activity against human NCI-H526 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
Antiproliferative activity against human NCI-H526 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay
|
[PMID: 36262394]
|
|
NCI-H661
|
IC50 |
0.13 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human NCI-H661 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
Antiproliferative activity against human NCI-H661 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
|
[PMID: 25874326]
|
|
NCI-H661
|
IC50 |
0.13 μM
Compound: Vorinostat
|
Antiproliferative activity against human NCI-H661 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human NCI-H661 cells incubated for 72 hrs by MTT assay
|
[PMID: 25953722]
|
|
NCI-H661
|
IC50 |
|
Antiproliferative activity against human H661 cells after 48 hrs
Antiproliferative activity against human H661 cells after 48 hrs
|
[PMID: 17157009]
|
|
NCI-H661
|
IC50 |
|
Antiproliferative activity against H661 cells after 48 hrs
Antiproliferative activity against H661 cells after 48 hrs
|
[PMID: 17897824]
|
|
NCI-H661
|
IC50 |
|
Antiproliferative activity against H661 cells
Antiproliferative activity against H661 cells
|
[PMID: 16904890]
|
|
NCI-H69
|
EC50 |
|
Cytotoxicity against human NCI-H69 cells after 72 hrs by trypan blue exclusion assay
Cytotoxicity against human NCI-H69 cells after 72 hrs by trypan blue exclusion assay
|
[PMID: 19093884]
|
|
NCI-H69
|
IC50 |
|
Cytotoxicity against human H69 cells
Cytotoxicity against human H69 cells
|
[PMID: 23906422]
|
|
NCI-H727
|
IC50 |
|
Cytotoxicity against human NCI-H727 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human NCI-H727 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 35858522]
|
|
NCI-H838
|
IC50 |
5.18 μM
Compound: Vorinostat
|
Antiproliferation activity against human NCI-H838 cells incubated for 72 hrs by MTT assay
Antiproliferation activity against human NCI-H838 cells incubated for 72 hrs by MTT assay
|
[PMID: 33493830]
|
|
NCI-H929
|
EC50 |
|
Antiproliferative activity against human NCI-H929 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human NCI-H929 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 31627059]
|
|
NCI-H929
|
IC50 |
|
Antiproliferative activity against human NCI-H929 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human NCI-H929 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25238284]
|
|
NCI-H929
|
IC50 |
|
Antiproliferative activity against human NCI-H929 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
Antiproliferative activity against human NCI-H929 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
|
[PMID: 26890114]
|
|
NCI-N87
|
IC50 |
1027 nM
Compound: 1; SAHA
|
Antiproliferative activity against human NCI-N87 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human NCI-N87 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
NCI/ADR-RES
|
GI50 |
0.16 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human NCI-ADR-RES cells after 72 hrs by MTS assay
Growth inhibition of human NCI-ADR-RES cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
NCI/ADR-RES
|
IC50 |
|
Cytotoxicity against human MCF7/ADR cells after 72 hrs by SRB assay
Cytotoxicity against human MCF7/ADR cells after 72 hrs by SRB assay
|
[PMID: 30819618]
|
|
NFF
|
IC50 |
|
Cytotoxicity against human NFF cells incubated for 72 hrs by SRB assay
Cytotoxicity against human NFF cells incubated for 72 hrs by SRB assay
|
[PMID: 39208744]
|
|
NFF
|
IC50 |
|
Cytotoxicity against human NFF cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human NFF cells after 72 hrs by sulforhodamine B assay
|
[PMID: 30245402]
|
|
NIH3T3
|
EC50 |
|
Cytotoxicity against mouse NIH/3T3 cells assessed as cell proliferation after 70 hrs by MTS assay
Cytotoxicity against mouse NIH/3T3 cells assessed as cell proliferation after 70 hrs by MTS assay
|
[PMID: 25974739]
|
|
NIH3T3
|
IC50 |
|
Antiproliferative activity against mouse NIH3T3 cells assessed as reduction in cell viability incubated for 3 days by CCK-8 assay
Antiproliferative activity against mouse NIH3T3 cells assessed as reduction in cell viability incubated for 3 days by CCK-8 assay
|
[PMID: 37463500]
|
|
NSC
|
IC50 |
4 μM
Compound: Chemical Probe: Vorinostat
|
Cytotoxicity against human fetal NSC assessed as reduction in cell vaibility incubated for 48 hrs by alamar blue assay
Cytotoxicity against human fetal NSC assessed as reduction in cell vaibility incubated for 48 hrs by alamar blue assay
|
[PMID: 30559935]
|
|
NUGC-3
|
GI50 |
2.79 μM
Compound: 2, SAHA
|
Growth inhibition of human NUGC3 cells by SRB assay
Growth inhibition of human NUGC3 cells by SRB assay
|
[PMID: 17904843]
|
|
NUGC-3
|
GI50 |
2.94 μM
Compound: 1, SAHA
|
Growth inhibition of human NUGC3 cells
Growth inhibition of human NUGC3 cells
|
[PMID: 20850971]
|
|
NUGC-3
|
GI50 |
2.94 μM
Compound: 1, SAHA, Zolinza, Vorinostat
|
Cytotoxicity against human NUGC3 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human NUGC3 cells assessed as growth inhibition by SRB assay
|
[PMID: 23163332]
|
|
NUGC-3
|
GI50 |
|
Growth inhibition of human NUGC3 cells after 5 days by sulforhodamine B assay
Growth inhibition of human NUGC3 cells after 5 days by sulforhodamine B assay
|
[PMID: 25811792]
|
|
NUGC-3
|
GI50 |
|
Growth inhibition of human NUGC3 cells measured after 5 days by sulforhodamine-B assay
Growth inhibition of human NUGC3 cells measured after 5 days by sulforhodamine-B assay
|
[PMID: 28011426]
|
|
Non-small cell lung cancer cell line
|
IC50 |
|
Antiproliferative activity against non-small cell lung cancer cell line (unknown origin)
Antiproliferative activity against non-small cell lung cancer cell line (unknown origin)
|
[PMID: 33077264]
|
|
OCI-AML-3
|
IC50 |
0.85 μM
Compound: 5; SAHA
|
Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
|
[PMID: 28765013]
|
|
OCI-AML-3
|
IC50 |
|
Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
OCI-AML-3
|
IC50 |
|
Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
Antiproliferative activity against human OCI-AML3 cells after 72 hrs by MTT assay
|
[PMID: 30629434]
|
|
OCI-AML2
|
IC50 |
0.78 μM
Compound: 5; SAHA
|
Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
|
[PMID: 28765013]
|
|
OCI-AML2
|
IC50 |
|
Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
Antiproliferative activity against human OCI-AML2 cells after 72 hrs by MTT assay
|
[PMID: 30629434]
|
|
OCI-Ly3
|
IC50 |
|
Antiproliferative activity against human OCI-LY3 cells after 72 hrs by MTT assay
Antiproliferative activity against human OCI-LY3 cells after 72 hrs by MTT assay
|
[PMID: 29150335]
|
|
OE19
|
GI50 |
1.42 μM
Compound: Vorinostat
|
Antiproliferative activity against human OE19 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
Antiproliferative activity against human OE19 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
|
[PMID: 31420257]
|
|
OE33
|
GI50 |
1.12 μM
Compound: Vorinostat
|
Antiproliferative activity against human OE33 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
Antiproliferative activity against human OE33 cells assessed as reduction in cell viability incubated for 72 hrs by presto blue assay
|
[PMID: 31420257]
|
|
ONS-76
|
IC50 |
2.04 μM
Compound: Vorinostat
|
Antiproliferative activity against human ONS76 cells after 72 hrs by Celltiter-Glo assay
Antiproliferative activity against human ONS76 cells after 72 hrs by Celltiter-Glo assay
|
[PMID: 28581289]
|
|
OPM-2
|
EC50 |
|
Antiproliferative activity against human OPM2 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human OPM2 cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 31627059]
|
|
OPM-2
|
IC50 |
2.91 μM
Compound: 1; SAHA
|
Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo assay
Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo assay
|
[PMID: 27541357]
|
|
OPM-2
|
IC50 |
|
Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo luminescent assay
Antiproliferative activity against human OPM2 cells after 48 hrs by CellTiter-Glo luminescent assay
|
[PMID: 28953386]
|
|
OVCAR-3
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
OVCAR-3
|
GI50 |
|
Antiproliferative activity against human OVCAR3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human OVCAR3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
OVCAR-3
|
GI50 |
2 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
Growth inhibition of human OVCAR3 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
OVCAR-4
|
GI50 |
4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human OVCAR4 cells after 72 hrs by MTS assay
Growth inhibition of human OVCAR4 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
OVCAR-5
|
GI50 |
0.79 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human OVCAR5 cells after 72 hrs by MTS assay
Growth inhibition of human OVCAR5 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
OVCAR-5
|
GI50 |
1.78 μM
Compound: 1, SAHA
|
Antiproliferative activity against human OVCAR5 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human OVCAR5 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 24119555]
|
|
OVCAR-5
|
GI50 |
|
Antiproliferative activity against human OVCAR5 cells assessed as growth inhibition after 48 hrs by SRB assay
Antiproliferative activity against human OVCAR5 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 25800646]
|
|
OVCAR-8
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human OVCAR8 cells after 72 hrs by MTS assay
Growth inhibition of human OVCAR8 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
Osteoclast-like
|
EC50 |
|
Compound was tested for anti-proliferative activity in human bone marrow cells
Compound was tested for anti-proliferative activity in human bone marrow cells
|
[PMID: 14698179]
|
|
PANC-1
|
GI50 |
|
Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
|
[PMID: 24999749]
|
|
PANC-1
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
PANC-1
|
IC50 |
0.9 μM
Compound: Vorinostat
|
Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
PANC-1
|
IC50 |
|
Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human PANC-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
PANC-1
|
IC50 |
|
Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
PANC-1
|
IC50 |
|
Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 37116762]
|
|
PANC-1
|
IC50 |
450 nM
Compound: 5, Zolinza
|
Antiproliferative activity against human PANC1 cells
Antiproliferative activity against human PANC1 cells
|
[PMID: 17588744]
|
|
PANC-1
|
IC50 |
|
Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
PBL
|
IC50 |
3.4 μM
Compound: Vorinostat
|
Cytotoxicity against human PBL cells assessed as cell growth inhibition after 72 hrs by MTS assay
Cytotoxicity against human PBL cells assessed as cell growth inhibition after 72 hrs by MTS assay
|
[PMID: 30004697]
|
|
PBMC
|
IC50 |
|
Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated TNF-alpha production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated TNF-alpha production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
|
10.1039/C3MD00285C
|
|
PBMC
|
IC50 |
|
Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated IL-6 production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
Antiinflammatory activity in human PBMC assessed as inhibition of LPS-stimulated IL-6 production incubated for 30 mins prior to LPS-challenge measured after overnight incubation
|
10.1039/C3MD00285C
|
|
PBMC
|
IC50 |
< 3.5 μM
Compound: Vorinostat
|
Cytotoxicity against human PBMC after 72 hrs by CellTiter-Glo luminescent cell viability assay
Cytotoxicity against human PBMC after 72 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 30365892]
|
|
PC-3
|
EC50 |
> 166.67 μM
Compound: SAHA
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 23820574]
|
|
PC-3
|
GI50 |
|
Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 28395150]
|
|
PC-3
|
GI50 |
|
Growth inhibition of human PC3 cells after 21 hrs by MTT assay
Growth inhibition of human PC3 cells after 21 hrs by MTT assay
|
[PMID: 17662606]
|
|
PC-3
|
GI50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
|
[PMID: 27344487]
|
|
PC-3
|
GI50 |
0.89 μM
Compound: 1, SAHA
|
Growth inhibition of PC3 cells by SRB assay
Growth inhibition of PC3 cells by SRB assay
|
[PMID: 17477518]
|
|
PC-3
|
GI50 |
0.89 μM
Compound: 2, SAHA
|
Antiproliferative activity against human PC3 cells by SRB assay
Antiproliferative activity against human PC3 cells by SRB assay
|
[PMID: 16723227]
|
|
PC-3
|
GI50 |
0.96 μM
Compound: Vorinostat
|
Growth inhibition of human PC3 cells after 72 hrs by CellTiter Glo assay
Growth inhibition of human PC3 cells after 72 hrs by CellTiter Glo assay
|
[PMID: 25182565]
|
|
PC-3
|
GI50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
|
[PMID: 21712146]
|
|
PC-3
|
GI50 |
1.21 μM
Compound: 1, SAHA
|
Growth inhibition of human PC3 cells after 48 hrs by SRB assay
Growth inhibition of human PC3 cells after 48 hrs by SRB assay
|
[PMID: 22439863]
|
|
PC-3
|
GI50 |
1.6 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human PC3 cells after 72 hrs by MTS assay
Growth inhibition of human PC3 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
PC-3
|
GI50 |
1.7 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
|
[PMID: 37875056]
|
|
PC-3
|
GI50 |
1.77 μM
Compound: 1, SAHA
|
Growth inhibition of human PC3 cells after 96 hrs by MTT assay
Growth inhibition of human PC3 cells after 96 hrs by MTT assay
|
[PMID: 26814680]
|
|
PC-3
|
GI50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 28629630]
|
|
PC-3
|
GI50 |
2 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human PC3 cells after 72 hrs by MTS assay
Growth inhibition of human PC3 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
PC-3
|
GI50 |
2.69 μM
Compound: 1, SAHA, Zolinza, Vorinostat
|
Cytotoxicity against human PC3 cells assessed as growth inhibition by SRB assay
Cytotoxicity against human PC3 cells assessed as growth inhibition by SRB assay
|
[PMID: 23163332]
|
|
PC-3
|
GI50 |
2.69 μM
Compound: 2, SAHA
|
Growth inhibition of human PC3 cells by SRB assay
Growth inhibition of human PC3 cells by SRB assay
|
[PMID: 17904843]
|
|
PC-3
|
GI50 |
|
Growth inhibition of human PC3 cells after 5 days by sulforhodamine B assay
Growth inhibition of human PC3 cells after 5 days by sulforhodamine B assay
|
[PMID: 25811792]
|
|
PC-3
|
GI50 |
|
Growth inhibition of human PC3 cells measured after 5 days by sulforhodamine-B assay
Growth inhibition of human PC3 cells measured after 5 days by sulforhodamine-B assay
|
[PMID: 28011426]
|
|
PC-3
|
GI50 |
2000 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human PC3 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human PC3 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
PC-3
|
GI50 |
4.6 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
PC-3
|
GI50 |
5 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC3 cells incubated for 72 hrs by CellTiter-Glo luminescence assay
Antiproliferative activity against human PC3 cells incubated for 72 hrs by CellTiter-Glo luminescence assay
|
[PMID: 30802730]
|
|
PC-3
|
GI50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 19822426]
|
|
PC-3
|
GI50 |
> 410 nM
Compound: Vorinostat
|
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
PC-3
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
PC-3
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
PC-3
|
IC50 |
0.85 μM
Compound: 1; SAHA
|
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 27541357]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 28953386]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells
Antiproliferative activity against human PC3 cells
|
[PMID: 29945795]
|
|
PC-3
|
IC50 |
0.94 μg/mL
Compound: SAHA
|
Cytotoxicity against human PC3 cells
Cytotoxicity against human PC3 cells
|
[PMID: 22036991]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 30243158]
|
|
PC-3
|
IC50 |
1.12 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC-3 cells incubated for 72 hrs by colorimetric method
Antiproliferative activity against human PC-3 cells incubated for 72 hrs by colorimetric method
|
[PMID: 37875056]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells
Antiproliferative activity against human PC3 cells
|
[PMID: 20451378]
|
|
PC-3
|
IC50 |
1.21 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human PC3 cells after 96 hrs by celltiter 96 assay
Antiproliferative activity against human PC3 cells after 96 hrs by celltiter 96 assay
|
[PMID: 21634430]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 21714538]
|
|
PC-3
|
IC50 |
1.34 μM
Compound: 1; SAHA
|
Antiproliferative activity against human PC-3 cells incubated for 96 hrs by MTT assay
Antiproliferative activity against human PC-3 cells incubated for 96 hrs by MTT assay
|
[PMID: 38503167]
|
|
PC-3
|
IC50 |
1.35 μM
Compound: Vorinostat
|
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC-3 cells incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human PC-3 cells incubated for 72 hrs by CCK-8 assay
|
[PMID: 37057760]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
10.1039/C4MD00203B
|
|
PC-3
|
IC50 |
1.44 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC-3 cells incubated for 48 hrs by colorimetric method
Antiproliferative activity against human PC-3 cells incubated for 48 hrs by colorimetric method
|
[PMID: 37875056]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 29223096]
|
|
PC-3
|
IC50 |
1.56 μM
Compound: 1; SAHA
|
Antiproliferative activity against human PC-3 cells incubated for 48 hrs by Sulforhodamine B staining method
Antiproliferative activity against human PC-3 cells incubated for 48 hrs by Sulforhodamine B staining method
|
[PMID: 33077264]
|
|
PC-3
|
IC50 |
1.7 μM
Compound: SAHA; 112
|
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by CCK-8 assay
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by CCK-8 assay
|
[PMID: 31881454]
|
|
PC-3
|
IC50 |
1.7 μM
Compound: Vorinostat
|
Cytotoxicity against human PC3 cells assessed as reduction in cell viability
Cytotoxicity against human PC3 cells assessed as reduction in cell viability
|
[PMID: 30660827]
|
|
PC-3
|
IC50 |
1.74 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human PC3 cells by MTT assay
Cytotoxicity against human PC3 cells by MTT assay
|
[PMID: 24766560]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability after 96 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability after 96 hrs by MTT assay
|
[PMID: 31883490]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells by colorimetric method
Cytotoxicity against human PC3 cells by colorimetric method
|
[PMID: 32916298]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 30879863]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells
Cytotoxicity against human PC3 cells
|
[PMID: 17691763]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 35152694]
|
|
PC-3
|
IC50 |
1.92 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
PC-3
|
IC50 |
1.98 μM
Compound: SAHA, Vorinostat
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 21924799]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 26216016]
|
|
PC-3
|
IC50 |
13.91 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 28371677]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 28336407]
|
|
PC-3
|
IC50 |
16.28 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition
Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition
|
[PMID: 38107170]
|
|
PC-3
|
IC50 |
1791 nM
Compound: 1; SAHA
|
Antiproliferative activity against human PC-3 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human PC-3 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells incubated for 96 hrs by resazurin assay
Antiproliferative activity against human PC3 cells incubated for 96 hrs by resazurin assay
|
[PMID: 32435375]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC-3 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human PC-3 cells incubated for 72 hrs by MTT assay
|
[PMID: 38452727]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells
Cytotoxicity against human PC3 cells
|
[PMID: 30245394]
|
|
PC-3
|
IC50 |
2.69 μM
Compound: 1, SAHA
|
Growth inhibition of human PC3 cells
Growth inhibition of human PC3 cells
|
[PMID: 20850971]
|
|
PC-3
|
IC50 |
2.78 μM
Compound: 1, SAHA
|
Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26122774]
|
|
PC-3
|
IC50 |
2.9 μM
Compound: Vorinostat
|
Antiproliferative activity against human PC3 cells by CCK8 assay
Antiproliferative activity against human PC3 cells by CCK8 assay
|
[PMID: 30660827]
|
|
PC-3
|
IC50 |
|
Anti-proliferative activity against human PC3 cells after 48 hrs by MTT assay
Anti-proliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 28947154]
|
|
PC-3
|
IC50 |
|
Anticancer activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Anticancer activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 34634618]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
PC-3
|
IC50 |
3.02 μM
Compound: XII; SAHA
|
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
PC-3
|
IC50 |
3.07 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay
|
[PMID: 29360358]
|
|
PC-3
|
IC50 |
|
Inhibition of PC3 cell proliferation (mean of two experiments)
Inhibition of PC3 cell proliferation (mean of two experiments)
|
[PMID: 17095213]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31546197]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
|
[PMID: 37079967]
|
|
PC-3
|
IC50 |
3.31 μM
Compound: 1; SAHA
|
Cytotoxicity against human PC-3 cells
Cytotoxicity against human PC-3 cells
|
[PMID: 33077264]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells incubated for 72 hrs by MTT assay
|
[PMID: 28987602]
|
|
PC-3
|
IC50 |
3.57 μM
Compound: SA, SAHA
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36242988]
|
|
PC-3
|
IC50 |
|
Inhibition of Class 2a histone deacetylase in human PC3 cells using Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
Inhibition of Class 2a histone deacetylase in human PC3 cells using Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
|
[PMID: 26349626]
|
|
PC-3
|
IC50 |
4.31 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
Antiproliferative activity against human PC3 cells after 48 hrs by SRB assay
|
[PMID: 24185378]
|
|
PC-3
|
IC50 |
403 nM
Compound: Vorinostat
|
Antiproliferative activity against human PC-3 cells
Antiproliferative activity against human PC-3 cells
|
[PMID: 37875056]
|
|
PC-3
|
IC50 |
|
Inhibition of Class 1 histone deacetylase in human PC3 cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
Inhibition of Class 1 histone deacetylase in human PC3 cells using Boc-Lys (acetyl)-AMC as substrate preincubated for 3 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
|
[PMID: 26349626]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 26349626]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 25311567]
|
|
PC-3
|
IC50 |
|
Concentration required to inhibit human PC-3 prostate carcinoma cells
Concentration required to inhibit human PC-3 prostate carcinoma cells
|
[PMID: 16033284]
|
|
PC-3
|
IC50 |
6.5 μM
Compound: vorinostat
|
Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by MTT assay
|
[PMID: 20403695]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 29533873]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells incubated for 24 hrs by CCK8 assay
Antiproliferative activity against human PC3 cells incubated for 24 hrs by CCK8 assay
|
[PMID: 32247729]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 26907204]
|
|
PC-3
|
IC50 |
|
Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26149591]
|
|
PC-3
|
IC50 |
873.26 nM
Compound: 1; SAHA
|
Antiproliferative activity against human PC3 cells measured after 48 hrs by sulforhodamine-B assay
Antiproliferative activity against human PC3 cells measured after 48 hrs by sulforhodamine-B assay
|
[PMID: 27886544]
|
|
PC-3
|
IC50 |
9.79 μM
Compound: 1, SAHA
|
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
|
[PMID: 24525003]
|
|
PC-3
|
IC50 |
|
Inhibition of human PC3 cell proliferation after 48 hrs by MTT assay
Inhibition of human PC3 cell proliferation after 48 hrs by MTT assay
|
[PMID: 23493449]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
PC-3
|
IC50 |
|
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 29787262]
|
|
PC-9
|
IC50 |
|
Antiproliferative activity against human PC-9 cells incubated for 72 hrs by celltiter-glo luminescent assay
Antiproliferative activity against human PC-9 cells incubated for 72 hrs by celltiter-glo luminescent assay
|
[PMID: 39178382]
|
|
PC-9
|
IC50 |
|
Antiproliferative activity against human PC-9 cells incubated for 24 to 48 hrs by CCK-8 assay
Antiproliferative activity against human PC-9 cells incubated for 24 to 48 hrs by CCK-8 assay
|
[PMID: 39145486]
|
|
PC-9
|
IC50 |
1181 nM
Compound: 1; SAHA
|
Antiproliferative activity against human PC-9 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human PC-9 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
PLC
|
IC50 |
|
Cytotoxicity against human PLC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human PLC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
PLC-PRF-5
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human PLC-PRF-5 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human PLC-PRF-5 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
PLC-PRF-5
|
IC50 |
1.87 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human PLC-PRF-5 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human PLC-PRF-5 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
PLC-PRF-5
|
IC50 |
|
Antiproliferative activity against human PLC-PRF-5 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human PLC-PRF-5 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
PT-45
|
IC50 |
4000 nM
Compound: 5, Zolinza
|
Antiproliferative activity against human drug-resistant PT45 cells
Antiproliferative activity against human drug-resistant PT45 cells
|
[PMID: 17588744]
|
|
RAW264.7
|
IC50 |
0.76 μM
Compound: 1, SAHA
|
Inhibition of LPS-stimulated TNFalpha production in RAW264.7 cells after 24 hrs by ELISA
Inhibition of LPS-stimulated TNFalpha production in RAW264.7 cells after 24 hrs by ELISA
|
[PMID: 17477518]
|
|
RAW264.7
|
IC50 |
1.88 μM
Compound: 1, SAHA
|
Inhibition of LPS-stimulated NO production in RAW264.7 cells after 24 hrs by ELISA
Inhibition of LPS-stimulated NO production in RAW264.7 cells after 24 hrs by ELISA
|
[PMID: 17477518]
|
|
RAW264.7
|
IC50 |
110 nM
Compound: SAHA, WR-308364
|
Antimalarial activity against Plasmodium falciparum infected in mouse RAW264.7 cells
Antimalarial activity against Plasmodium falciparum infected in mouse RAW264.7 cells
|
[PMID: 18644969]
|
|
RPMI-8226
|
GI50 |
1.5 μM
Compound: SAHA; NSC759852
|
Cytotoxicity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
Cytotoxicity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
|
[PMID: 36306372]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue dye based assay
Antiproliferative activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 72 hrs by alamar blue dye based assay
|
[PMID: 37660484]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
|
[PMID: 31413795]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
|
[PMID: 29534936]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI-8226 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
Antiproliferative activity against human RPMI-8226 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
|
[PMID: 31865013]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 aqueous non-radioactive cell proliferation assay
|
[PMID: 26890114]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
Antiproliferative activity against human RPMI8226 cells after 72 hrs by CellTiter 96 AQueous Non-Radioactive assay
|
[PMID: 28213282]
|
|
RPMI-8226
|
IC50 |
|
Growth inhibition of human RPMI8226 cells after 72 hrs by MTT assay
Growth inhibition of human RPMI8226 cells after 72 hrs by MTT assay
|
[PMID: 30594434]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI8226 cells after 72 hrs by WST8 assay
Antiproliferative activity against human RPMI8226 cells after 72 hrs by WST8 assay
|
[PMID: 25261927]
|
|
RPMI-8226
|
IC50 |
|
Cytotoxicity against human RPMI8226 cells assessed as cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human RPMI8226 cells assessed as cell viability after 72 hrs by CCK8 assay
|
[PMID: 26211462]
|
|
RPMI-8226
|
IC50 |
|
Cytotoxicity against human RPMI8226 cells after 72 hrs by MTS assay
Cytotoxicity against human RPMI8226 cells after 72 hrs by MTS assay
|
[PMID: 25490132]
|
|
RPMI-8226
|
IC50 |
|
Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay
Cytotoxicity against human RPMI8226 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
Antiproliferative activity against human RPMI8226 cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
RPMI-8226
|
IC50 |
|
Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human RPMI8226 cells incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
RS4-11
|
IC50 |
|
Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 34954595]
|
|
RWPE-1
|
GI50 |
|
Antiproliferative activity against human RWPE-1 cells assessed as growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human RWPE-1 cells assessed as growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 37633202]
|
|
RWPE-1
|
IC50 |
0.48 μM
Compound: 1; SAHA
|
Cytotoxicity against human RWPE-1 cells
Cytotoxicity against human RWPE-1 cells
|
[PMID: 33077264]
|
|
RWPE-1
|
IC50 |
|
Cytotoxicity against human RWPE1 cells
Cytotoxicity against human RWPE1 cells
|
[PMID: 30245394]
|
|
RXF 393
|
GI50 |
|
Antiproliferative activity against human RXF393 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human RXF393 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
RXF 393
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human RXF393 cells after 72 hrs by MTS assay
Growth inhibition of human RXF393 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
RXF 631
|
GI50 |
2 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human RXF631L cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human RXF631L cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
Raji
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human Raji cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human Raji cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
Raji
|
IC50 |
|
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
|
[PMID: 28325601]
|
|
Raji
|
IC50 |
|
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
|
[PMID: 29534936]
|
|
Raji
|
IC50 |
1.11 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human Raji cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human Raji cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
Raji
|
IC50 |
|
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
|
[PMID: 30629434]
|
|
Raji
|
IC50 |
|
Antiproliferative activity against human Raji cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human Raji cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
Raji
|
IC50 |
3 μM
Compound: Vorinostat
|
Antiproliferative activity against human Raji cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human Raji cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
Raji
|
IC50 |
|
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
Antiproliferative activity against human Raji cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
Raji
|
IC50 |
|
Antiproliferative activity against human Raji cells after 3 days by MTT assay
Antiproliferative activity against human Raji cells after 3 days by MTT assay
|
[PMID: 28601509]
|
|
Ramos
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against human Ramos cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against human Ramos cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
Ramos
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human Ramos cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human Ramos cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
Ramos
|
IC50 |
|
Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
|
[PMID: 28325601]
|
|
Ramos
|
IC50 |
|
Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
|
[PMID: 29534936]
|
|
Ramos
|
IC50 |
0.62 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
Ramos
|
IC50 |
|
Antiproliferative activity against human Ramos cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human Ramos cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
Ramos
|
IC50 |
|
Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38048697]
|
|
Ramos
|
IC50 |
|
Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
Antiproliferative activity against human Ramos cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
Ramos
|
IC50 |
|
Cytotoxicity against human Ramos cells after 72 hrs by MTT assay
Cytotoxicity against human Ramos cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
Rec1
|
IC50 |
0.35 μM
Compound: SAHA; 6
|
Antiproliferative activity against human REC1 cells incubated for 72 hrs by celltiter-glo luminescent assay
Antiproliferative activity against human REC1 cells incubated for 72 hrs by celltiter-glo luminescent assay
|
[PMID: 39178382]
|
|
S2
|
IC50 |
|
Inhibition of Plasmodium falciparum HDAC1 expressed in Drosophila melanogaster S2 cells
Inhibition of Plasmodium falciparum HDAC1 expressed in Drosophila melanogaster S2 cells
|
[PMID: 19317450]
|
|
S9
|
IC50 |
120.5 nM
Compound: 6, SAHA
|
Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
|
[PMID: 25906087]
|
|
S9
|
IC50 |
21.5 nM
Compound: 6, SAHA
|
Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
|
[PMID: 25906087]
|
|
S9
|
IC50 |
34.5 nM
Compound: 6, SAHA
|
Inhibition of full length human recombinant HDAC11 expressed in baculovirus infected insect S9 cells after 30 mins by fluorescence assay
Inhibition of full length human recombinant HDAC11 expressed in baculovirus infected insect S9 cells after 30 mins by fluorescence assay
|
[PMID: 25906087]
|
|
S9
|
IC50 |
|
Inhibition of full length human recombinant HDAC8 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
Inhibition of full length human recombinant HDAC8 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
|
[PMID: 25906087]
|
|
S9
|
IC50 |
58.5 nM
Compound: 6, SAHA
|
Inhibition of full length human recombinant HDAC3 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
Inhibition of full length human recombinant HDAC3 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Ac)-AMC as substrate after 30 mins by fluorescence assay
|
[PMID: 25906087]
|
|
S9
|
IC50 |
> 100 nM
Compound: 6, SAHA
|
Inhibition of human recombinant HDAC4 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
Inhibition of human recombinant HDAC4 expressed in baculovirus infected insect S9 cells using Ac-Leu-GlyLys(Tfa)-AMC as substrate after 30 mins by fluorescence assay
|
[PMID: 25906087]
|
|
SAOS-2
|
IC50 |
|
Cytotoxicity against human Saos2 cells
Cytotoxicity against human Saos2 cells
|
[PMID: 17691763]
|
|
SCC-15
|
IC50 |
|
Antiproliferative activity against human SCC15 cells
Antiproliferative activity against human SCC15 cells
|
[PMID: 20143778]
|
|
SCC-25
|
IC50 |
|
Antiproliferative activity against human SCC25 cells
Antiproliferative activity against human SCC25 cells
|
[PMID: 20143778]
|
|
SF-268
|
GI50 |
1.6 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SF268 cells after 72 hrs by MTS assay
Growth inhibition of human SF268 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SF-295
|
GI50 |
1.6 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SF295 cells after 72 hrs by MTS assay
Growth inhibition of human SF295 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SF-539
|
GI50 |
2 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SF539 cells after 72 hrs by MTS assay
Growth inhibition of human SF539 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SF-539
|
GI50 |
2 μM
Compound: SAHA; NSC759852
|
Cytotoxicity against human SF-539 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
Cytotoxicity against human SF-539 cells assessed as cell growth inhibition incubated for 24 hrs by MTT assay
|
[PMID: 36306372]
|
|
SGC-7901
|
IC50 |
0.64 μM
Compound: 1; SAHA
|
Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
|
[PMID: 34656899]
|
|
SGC-7901
|
IC50 |
|
Antiproliferative activity against human SGC7901 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human SGC7901 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
|
[PMID: 31400938]
|
|
SGC-7901
|
IC50 |
1.4 μM
Compound: Vorinostat
|
Antiproliferative activity against human SGC-7901 cells
Antiproliferative activity against human SGC-7901 cells
|
[PMID: 37875056]
|
|
SGC-7901
|
IC50 |
|
Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34628244]
|
|
SGC-7901
|
IC50 |
|
Antiproliferative activity against human SGC-7901 cells measured after 48 hrs by MTT assay
Antiproliferative activity against human SGC-7901 cells measured after 48 hrs by MTT assay
|
[PMID: 35041998]
|
|
SGC-7901
|
IC50 |
|
Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 38261411]
|
|
SGC-7901
|
IC50 |
3.3 μM
Compound: Vorinostat
|
Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay
|
[PMID: 35608269]
|
|
SGC-7901
|
IC50 |
|
Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
SH-SY5Y
|
EC50 |
|
Antiproliferative activity against human SH-SY5Y cells after 72 hrs by XTT assay
Antiproliferative activity against human SH-SY5Y cells after 72 hrs by XTT assay
|
[PMID: 21548582]
|
|
SH-SY5Y
|
EC50 |
|
Antiproliferative activity against human SH-SY5Y cells after 48 hrs by XTT assay
Antiproliferative activity against human SH-SY5Y cells after 48 hrs by XTT assay
|
[PMID: 21548582]
|
|
SH-SY5Y
|
EC50 |
|
Antiproliferative activity against human SH-SY5Y cells after 24 hrs by XTT assay
Antiproliferative activity against human SH-SY5Y cells after 24 hrs by XTT assay
|
[PMID: 21548582]
|
|
SH-SY5Y
|
IC50 |
|
Inhibition of HDAC in human SHSY5Y cells by fluorimetric cellular activity assay
Inhibition of HDAC in human SHSY5Y cells by fluorimetric cellular activity assay
|
[PMID: 19344175]
|
|
SH-SY5Y
|
IC50 |
|
Antiproliferative activity against human SH-SY5Y cells harboring ALK F1174L mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
Antiproliferative activity against human SH-SY5Y cells harboring ALK F1174L mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
|
[PMID: 34237620]
|
|
SH-SY5Y
|
IC50 |
|
Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 19344175]
|
|
SH-SY5Y
|
IC50 |
3.59 μM
Compound: Vorinostat
|
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 72 hrs by MUH reagent based spectrophotometric analysis
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 72 hrs by MUH reagent based spectrophotometric analysis
|
[PMID: 38911150]
|
|
SH-SY5Y
|
IC50 |
32.2 μM
Compound: Vorinostat
|
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 24 hrs by MUH reagent based spectrophotometric analysis
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 24 hrs by MUH reagent based spectrophotometric analysis
|
[PMID: 38911150]
|
|
SH-SY5Y
|
IC50 |
5.43 μM
Compound: Vorinostat
|
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 48 hrs by MUH reagent based spectrophotometric analysis
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 48 hrs by MUH reagent based spectrophotometric analysis
|
[PMID: 38911150]
|
|
SH-SY5Y
|
IC50 |
|
Cytotoxicity against human SH-SY5Y cells assessed as cell viability measured after 36 hrs by CCK8 assay
Cytotoxicity against human SH-SY5Y cells assessed as cell viability measured after 36 hrs by CCK8 assay
|
[PMID: 36645952]
|
|
SK-BR-3
|
EC50 |
2.1 μM
Compound: 1a, SAHA
|
Antiproliferative activity against human SK-BR-3 cells after 48 hrs by cell titer-glo assay
Antiproliferative activity against human SK-BR-3 cells after 48 hrs by cell titer-glo assay
|
[PMID: 20218673]
|
|
SK-BR-3
|
GI50 |
1.2 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human SK-BR-3 cells after 72 hrs by WST1 assay
Cytotoxicity against human SK-BR-3 cells after 72 hrs by WST1 assay
|
[PMID: 24015327]
|
|
SK-BR-3
|
IC50 |
|
Antiproliferative activity against human SKBR3 cells
Antiproliferative activity against human SKBR3 cells
|
[PMID: 18247554]
|
|
SK-BR-3
|
IC50 |
|
Antiproliferative activity against human SK-BR-3 cells after hrs by ATP content assay
Antiproliferative activity against human SK-BR-3 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
SK-BR-3
|
IC50 |
2.13 μM
Compound: Vorinostat
|
Antiproliferation activity against human SK-BR-3 cells incubated for 72 hrs by MTT assay
Antiproliferation activity against human SK-BR-3 cells incubated for 72 hrs by MTT assay
|
[PMID: 33493830]
|
|
SK-BR-3
|
IC50 |
|
Antiproliferative activity against human SK-BR-3 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
Antiproliferative activity against human SK-BR-3 cells expressing HER2 assessed as reduction in cell viability measured after 48 hrs by MTT assay
|
[PMID: 27769671]
|
|
SK-BR-3
|
IC50 |
|
Cytotoxicity against human SKBR3 cells
Cytotoxicity against human SKBR3 cells
|
[PMID: 17691763]
|
|
SK-BR-3
|
IC50 |
|
Cytotoxicity against human SKBR3 cells overexpressing HER2 by resazurin dye reduction assay
Cytotoxicity against human SKBR3 cells overexpressing HER2 by resazurin dye reduction assay
|
[PMID: 21080629]
|
|
SK-BR-3
|
IC50 |
|
Cytotoxicity against human SKBR3 cells after 72 hrs by MTT assay
Cytotoxicity against human SKBR3 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
SK-HEP1
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human SK-HEP1 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human SK-HEP1 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
SK-HEP1
|
IC50 |
1.85 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human SK-HEP1 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human SK-HEP1 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
SK-HEP1
|
IC50 |
|
Anticancer activity against human SK-HEP1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Anticancer activity against human SK-HEP1 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 34634618]
|
|
SK-HEP1
|
IC50 |
|
Antiproliferative activity against human SKHEP1 cells after hrs by ATP content assay
Antiproliferative activity against human SKHEP1 cells after hrs by ATP content assay
|
[PMID: 20143778]
|
|
SK-HEP1
|
IC50 |
|
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
SK-MEL-2
|
GI50 |
1.3 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SK-MEL-2 cells after 72 hrs by MTS assay
Growth inhibition of human SK-MEL-2 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SK-MEL-28
|
GI50 |
1 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTS assay
Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SK-MEL-28
|
IC50 |
0.482 μM
Compound: 1; SAHA
|
Antiproliferative activity against human SK-MEL-28 cells after 72 hrs by resazurin dye based fluorescence assay
Antiproliferative activity against human SK-MEL-28 cells after 72 hrs by resazurin dye based fluorescence assay
|
[PMID: 29456804]
|
|
SK-MEL-5
|
GI50 |
0.63 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SK-MEL-5 cells after 72 hrs by MTS assay
Growth inhibition of human SK-MEL-5 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SK-MES-1
|
EC50 |
|
Cytotoxicity against human SKMES1 cells after 72 hrs by trypan blue exclusion assay
Cytotoxicity against human SKMES1 cells after 72 hrs by trypan blue exclusion assay
|
[PMID: 19093884]
|
|
SK-MES-1
|
IC50 |
|
Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
|
[PMID: 22260166]
|
|
SK-N-AS
|
IC50 |
0.7 μM
Compound: Vorinostat
|
Antiproliferative activity against human SK-N-AS cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
Antiproliferative activity against human SK-N-AS cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay
|
[PMID: 31391882]
|
|
SK-N-BE(2)
|
IC50 |
0.21 μM
Compound: Vorinostat
|
Antiproliferative activity against human SK-N-BE(2) cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human SK-N-BE(2) cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
SK-N-BE(2)
|
IC50 |
|
Antiproliferative activity against human SK-N-BE(2) cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
Antiproliferative activity against human SK-N-BE(2) cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
|
[PMID: 37079967]
|
|
SK-OV-3
|
EC50 |
|
Inhibition of human SKOV3 cells
Inhibition of human SKOV3 cells
|
[PMID: 18247554]
|
|
SK-OV-3
|
EC50 |
2.5 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human SK-OV-3 cells
Effective Concentration of compound to inhibit the growth of human SK-OV-3 cells
|
[PMID: 15715470]
|
|
SK-OV-3
|
GI50 |
1 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SKOV3 cells after 72 hrs by MTS assay
Growth inhibition of human SKOV3 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SK-OV-3
|
GI50 |
2.5 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
SK-OV-3
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human SK-OV-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human SK-OV-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
SK-OV-3
|
IC50 |
1.66 mM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
|
[PMID: 20171895]
|
|
SK-OV-3
|
IC50 |
|
Antiproliferative activity against human SKOV3 cells after 72 hrs by MTT assay
Antiproliferative activity against human SKOV3 cells after 72 hrs by MTT assay
|
[PMID: 31177073]
|
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SK-OV-3 cells
Cytotoxicity against human SK-OV-3 cells
|
[PMID: 17691763]
|
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells overexpressing HER2 by resazurin dye reduction assay
Cytotoxicity against human SKOV3 cells overexpressing HER2 by resazurin dye reduction assay
|
[PMID: 21080629]
|
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells
Cytotoxicity against human SKOV3 cells
|
[PMID: 23906422]
|
|
SK-OV-3
|
IC50 |
|
Cytotoxicity against human SKOV3 cells after 72 hrs by MTT assay
Cytotoxicity against human SKOV3 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
SMMC-7721
|
IC50 |
|
Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
|
[PMID: 31120744]
|
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC7721 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human SMMC7721 cells incubated for 48 hrs by MTT assay
|
[PMID: 30851694]
|
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
|
[PMID: 31991336]
|
|
SMMC-7721
|
IC50 |
5.46 μM
Compound: 1; CTCL
|
Cytotoxicity against human SMMC-7721 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
Cytotoxicity against human SMMC-7721 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
|
[PMID: 33143937]
|
|
SMMC-7721
|
IC50 |
5.46 μM
Compound: 1; SAHA
|
Cytotoxicity against human SMMC-7721 cells
Cytotoxicity against human SMMC-7721 cells
|
[PMID: 33077264]
|
|
SMMC-7721
|
IC50 |
5.46 μM
Compound: Vorinostat
|
Cytotoxicity against human SMMC-7721 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human SMMC-7721 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
|
[PMID: 29288941]
|
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
|
[PMID: 30108831]
|
|
SMMC-7721
|
IC50 |
|
Antiproliferative activity against human SMMC-7721 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human SMMC-7721 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
SN12C
|
GI50 |
2 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SN12C cells after 72 hrs by MTS assay
Growth inhibition of human SN12C cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SNB-19
|
GI50 |
0.63 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SNB19 cells after 72 hrs by MTS assay
Growth inhibition of human SNB19 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SNB-75
|
GI50 |
0.79 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SNB75 cells after 72 hrs by MTS assay
Growth inhibition of human SNB75 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SNB-75
|
GI50 |
|
Antiproliferative activity against human SNB75 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human SNB75 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
SNB-78
|
EC50 |
|
Inhibition of human SNB78 cells
Inhibition of human SNB78 cells
|
[PMID: 18247554]
|
|
SNB-78
|
EC50 |
16 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human SNB-78 cells
Effective Concentration of compound to inhibit the growth of human SNB-78 cells
|
[PMID: 15715470]
|
|
SNB-78
|
GI50 |
16 μM
Compound: 2, (SAHA, vorinostat)
|
Growth inhibition of human SNB78 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human SNB78 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 19419205]
|
|
SNU-16
|
IC50 |
0.29 μM
Compound: 3; SAHA
|
Antiproliferative activity against human SNU-16 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human SNU-16 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 36449947]
|
|
SNU-387
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human SNU-387 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human SNU-387 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
SNU-387
|
IC50 |
2.45 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human SNU-387 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human SNU-387 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
SNU-398
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human SNU-398 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human SNU-398 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
SNU-398
|
IC50 |
1.39 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human SNU-398 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human SNU-398 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
SNU-423
|
IC50 |
|
Antiproliferative activity against human SNU-423 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human SNU-423 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 34509167]
|
|
SQ20B
|
IC50 |
|
Inhibition of human SQ20B cells
Inhibition of human SQ20B cells
|
[PMID: 18247554]
|
|
SR
|
GI50 |
|
Antiproliferative activity against human SR cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human SR cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
SR
|
GI50 |
0.4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SR cells after 72 hrs by MTS assay
Growth inhibition of human SR cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SU-DHL-6
|
IC50 |
0.43 μM
Compound: Vorinostat
|
Cytotoxicity against human SU-DHL-6 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human SU-DHL-6 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
SU-DHL-6
|
IC50 |
0.58 μM
Compound: Vor; SAHA
|
Antiproliferative activity against human SU-DHL-6 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
Antiproliferative activity against human SU-DHL-6 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay
|
[PMID: 29360358]
|
|
SU-DHL10
|
IC50 |
0.47 μM
Compound: 1; SAHA
|
Antiproliferative activity against human SU-DHL-10 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human SU-DHL-10 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36153841]
|
|
SU.86.86
|
IC50 |
|
Antiproliferative activity against human SU.86.86 cells after 72 hrs by MTT assay
Antiproliferative activity against human SU.86.86 cells after 72 hrs by MTT assay
|
[PMID: 18642892]
|
|
SU.86.86
|
IC50 |
|
Antiproliferative activity against human SU-8686 cells by MTT assay
Antiproliferative activity against human SU-8686 cells by MTT assay
|
[PMID: 19419863]
|
|
SU.86.86
|
IC50 |
1.3 μM
Compound: 1a, SAHA
|
Growth inhibition of human SU-8686 cells after 72 hrs by MTS assay
Growth inhibition of human SU-8686 cells after 72 hrs by MTS assay
|
[PMID: 20055418]
|
|
SU.86.86
|
IC50 |
|
Cytotoxicity against human SU 86.86 cells after 72 hrs by MTT assay
Cytotoxicity against human SU 86.86 cells after 72 hrs by MTT assay
|
[PMID: 18494463]
|
|
SUM-159-PT
|
IC50 |
|
Cytotoxicity against human SUM159PT cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human SUM159PT cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
SUM-159-PT
|
IC50 |
|
Cytotoxicity against human SUM159PT cells harboring wild type BRCA1 and wild type BRCA2 assessed as reduction in cell viability
Cytotoxicity against human SUM159PT cells harboring wild type BRCA1 and wild type BRCA2 assessed as reduction in cell viability
|
[PMID: 36053318]
|
|
SW-620
|
GI50 |
0.54 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human SW620 cells after 48 hrs by SRB assay
Cytotoxicity against human SW620 cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
SW-620
|
GI50 |
0.63 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SW620 cells after 72 hrs by MTS assay
Growth inhibition of human SW620 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SW-620
|
GI50 |
0.63 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human SW620 cells after 72 hrs by MTS assay
Growth inhibition of human SW620 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
SW-620
|
IC50 |
|
Cytotoxicity against human SW620 cells
Cytotoxicity against human SW620 cells
|
[PMID: 22036991]
|
|
SW-620
|
IC50 |
|
Inhibition of human SW620 cells
Inhibition of human SW620 cells
|
[PMID: 18247554]
|
|
SW-620
|
IC50 |
|
Cytotoxicity against human SW620 cells by colorimetric method
Cytotoxicity against human SW620 cells by colorimetric method
|
[PMID: 32916298]
|
|
SW-620
|
IC50 |
1.12 μM
Compound: Vorinostat
|
Antiproliferative activity against human SW620 cells incubated for 72 hrs by colorimetric method
Antiproliferative activity against human SW620 cells incubated for 72 hrs by colorimetric method
|
[PMID: 37875056]
|
|
SW-620
|
IC50 |
1.44 μM
Compound: Vorinostat
|
Antiproliferative activity against human SW620 cells incubated for 48 hrs by colorimetric method
Antiproliferative activity against human SW620 cells incubated for 48 hrs by colorimetric method
|
[PMID: 37875056]
|
|
SW-620
|
IC50 |
1.7 μM
Compound: SAHA; 112
|
Antiproliferative activity against human SW620 cells assessed as inhibition of cell proliferation by CCK-8 assay
Antiproliferative activity against human SW620 cells assessed as inhibition of cell proliferation by CCK-8 assay
|
[PMID: 31881454]
|
|
SW-620
|
IC50 |
1.7 μM
Compound: Vorinostat
|
Cytotoxicity against human SW620 cells assessed as reduction in cell viability
Cytotoxicity against human SW620 cells assessed as reduction in cell viability
|
[PMID: 30660827]
|
|
SW-620
|
IC50 |
2.8 μM
Compound: Vorinostat
|
Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 32791404]
|
|
SW-620
|
IC50 |
|
Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 48 hrs by MTT assay
|
[PMID: 31546197]
|
|
SW-620
|
IC50 |
3.7 μM
Compound: SAHA, Vorinostat, Zolinza
|
Antiproliferative activity against human SW620 cells after 48 hrs by SRB assay
Antiproliferative activity against human SW620 cells after 48 hrs by SRB assay
|
[PMID: 24185378]
|
|
SW-620
|
IC50 |
|
Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
|
[PMID: 28987602]
|
|
SW-620
|
IC50 |
4.31 μM
Compound: Vorinostat
|
Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by SRB assay
Cytotoxicity against human SW620 cells assessed as inhibition of cell growth by SRB assay
|
[PMID: 32791404]
|
|
SW-620
|
IC50 |
|
Antiproliferative activity against human SW620 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human SW620 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26555243]
|
|
SW-620
|
IC50 |
403 nM
Compound: Vorinostat
|
Antiproliferative activity against human SW620 cells
Antiproliferative activity against human SW620 cells
|
[PMID: 37875056]
|
|
SW-620
|
IC50 |
|
Antiproliferative activity against human SW620 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
Antiproliferative activity against human SW620 cells assessed as reduction in cell viability measured after 24 to 48 hrs by MTT assay
|
[PMID: 32153186]
|
|
SW1990
|
IC50 |
|
Antiproliferative activity against human SW1990 cells after 96 hrs by MTT assay
Antiproliferative activity against human SW1990 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
SW1990
|
IC50 |
|
Antiproliferative activity against human SW1990 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human SW1990 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36097406]
|
|
SW480
|
IC50 |
|
Antiproliferative activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
SW480
|
IC50 |
|
Antiproliferative activity against human SW480 cells measured after 72 hrs
Antiproliferative activity against human SW480 cells measured after 72 hrs
|
[PMID: 35697181]
|
|
SW480
|
IC50 |
|
Antiproliferative activity against human SW480 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human SW480 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 26555243]
|
|
Sf21
|
IC50 |
|
Inhibition of Flag tagged human recombinant HDAC3 expressed in Sf21 cells coexpressing SMRT DAD domain
Inhibition of Flag tagged human recombinant HDAC3 expressed in Sf21 cells coexpressing SMRT DAD domain
|
[PMID: 21080629]
|
|
Sf21
|
IC50 |
|
Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assay
Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assay
|
[PMID: 26890116]
|
|
Sf21
|
IC50 |
0.306 μM
Compound: 1; SAHA
|
Inhibition of full length human recombinant C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
Inhibition of full length human recombinant C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in sf21 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
|
[PMID: 27541357]
|
|
Sf21
|
IC50 |
|
Inhibition of Flag tagged human recombinant HDAC8 expressed in Sf21 cells
Inhibition of Flag tagged human recombinant HDAC8 expressed in Sf21 cells
|
[PMID: 21080629]
|
|
Sf21
|
IC50 |
|
Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf21 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf21 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
|
[PMID: 30245394]
|
|
Sf9
|
IC50 |
0.0058 μM
Compound: 1; SAHA
|
Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 5 hrs by electrophoretic mobility shift assay
Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 5 hrs by electrophoretic mobility shift assay
|
[PMID: 31938464]
|
|
Sf9
|
IC50 |
0.00657 μM
Compound: 1; SAHA
|
Inhibition of recombinant full length human HDAC3 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 3 hrs by electrophoretic mobility shift assay
Inhibition of recombinant full length human HDAC3 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 3 hrs by electrophoretic mobility shift assay
|
[PMID: 31938464]
|
|
Sf9
|
IC50 |
0.0097 μM
Compound: Vorinostat
|
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay
|
[PMID: 31762274]
|
|
Sf9
|
IC50 |
0.02 μM
Compound: 1; SAHA
|
Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells preincubated with enzyme followed by fluorogenic Arg-His-Lys-Lys(Ac)-AMC substrate addition measured after 2 hrs by fluorescence assay
|
[PMID: 27541357]
|
|
Sf9
|
IC50 |
|
Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells using RHK-K(Ac)-AMC as substrate incubated for 90 mins by fluorescence assay
Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in sf9 cells using RHK-K(Ac)-AMC as substrate incubated for 90 mins by fluorescence assay
|
[PMID: 26890116]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC6 expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
Inhibition of recombinant full length human HDAC6 expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
|
10.1039/C4MD00203B
|
|
Sf9
|
IC50 |
0.038 μM
Compound: Vorinostat
|
Inhibition of recombinant human full length C-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
Inhibition of recombinant human full length C-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
|
[PMID: 31420257]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC1 (1 to 482 amino acids) expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
Inhibition of recombinant full length human HDAC1 (1 to 482 amino acids) expressed in Baculovirus infected insect Sf9 cells incubated for 30 mins measured by fluorescence assay
|
10.1039/C4MD00203B
|
|
Sf9
|
IC50 |
|
Inhibition of C-terminal GST-tagged human recombinant HDAC2 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
Inhibition of C-terminal GST-tagged human recombinant HDAC2 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
|
[PMID: 26907204]
|
|
Sf9
|
IC50 |
0.089 μM
Compound: Vorinostat
|
Inhibition of recombinant human full length C-terminal Flag/His-tagged HDAC1 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
Inhibition of recombinant human full length C-terminal Flag/His-tagged HDAC1 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
|
[PMID: 31420257]
|
|
Sf9
|
IC50 |
0.102 μM
Compound: Vorinostat
|
Inhibition of human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells ZMAL as substrate incubated for 90 mins by fluorescence assay
Inhibition of human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells ZMAL as substrate incubated for 90 mins by fluorescence assay
|
[PMID: 31762274]
|
|
Sf9
|
IC50 |
0.105 μM
Compound: Vorinostat
|
Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
|
[PMID: 31420257]
|
|
Sf9
|
IC50 |
0.111 μM
Compound: Vorinostat
|
Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate incubated for 90 mins by fluorescence assay
Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate incubated for 90 mins by fluorescence assay
|
[PMID: 31762274]
|
|
Sf9
|
IC50 |
0.146 μM
Compound: Vorinostat
|
Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay
Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay
|
[PMID: 31762274]
|
|
Sf9
|
IC50 |
0.183 μM
Compound: Vorinostat
|
Inhibition of recombinant human full length C-terminal Flag-tagged HDAC2 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
Inhibition of recombinant human full length C-terminal Flag-tagged HDAC2 expressed in baculovirus infected Sf9 cells using ZMAL as substrate incubated for 90 mins by fluorometric method
|
[PMID: 31420257]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC8 expressed in Baculovirus infected insect Sf9 cells preincubated for 30 mins followed by substrate addition measured after 15 to 45 mins by luminescence assay
Inhibition of recombinant full length human HDAC8 expressed in Baculovirus infected insect Sf9 cells preincubated for 30 mins followed by substrate addition measured after 15 to 45 mins by luminescence assay
|
10.1039/C4MD00203B
|
|
Sf9
|
IC50 |
0.497 μM
Compound: 1; SAHA
|
Inhibition of recombinant full length human HDAC8 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by electrophoretic mobility shift assay
Inhibition of recombinant full length human HDAC8 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by electrophoretic mobility shift assay
|
[PMID: 31938464]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full-length human C-terminal HDAC8 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
Inhibition of recombinant full-length human C-terminal HDAC8 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
|
[PMID: 30245394]
|
|
Sf9
|
IC50 |
|
Inhibition of human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
Inhibition of human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
|
[PMID: 30245394]
|
|
Sf9
|
IC50 |
101 nM
Compound: Vorinostat
|
Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay
Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay
|
[PMID: 31391882]
|
|
Sf9
|
IC50 |
|
Inhibition of full length recombinant GST-tagged N-terminal human HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
Inhibition of full length recombinant GST-tagged N-terminal human HDAC6 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
|
[PMID: 31531206]
|
|
Sf9
|
IC50 |
|
Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AMC preincubated for 15 mins followed by substrate addition measured after 1 hr by fluorescence assay
Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AMC preincubated for 15 mins followed by substrate addition measured after 1 hr by fluorescence assay
|
[PMID: 27186676]
|
|
Sf9
|
IC50 |
|
Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
|
[PMID: 30594434]
|
|
Sf9
|
IC50 |
144.7 nM
Compound: SAHA; Vor
|
Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence based micro plate reader analysis
Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 residues) in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence based micro plate reader analysis
|
[PMID: 32321249]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
|
[PMID: 30629434]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
Inhibition of recombinant C-terminal His-tagged full length human HDAC2 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
|
[PMID: 25815139]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
|
[PMID: 31505452]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
Inhibition of recombinant N-terminal GST-tagged full length human HDAC6 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
|
[PMID: 25815139]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
Inhibition of recombinant full length human HDAC1 (1 to 482) expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
|
[PMID: 25815139]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
|
Inhibition of C-terminal His-tagged human recombinant HDAC8 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
Inhibition of C-terminal His-tagged human recombinant HDAC8 expressed in Sf9 cells after 30 mins by microtiter plate reader analysis
|
[PMID: 26907204]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant C-terminal His/FLAG-tagged HDAC1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr
Inhibition of recombinant C-terminal His/FLAG-tagged HDAC1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using Ac-peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr
|
[PMID: 31117517]
|
|
Sf9
|
IC50 |
|
Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 240 mins by fluorescence based assay
Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 240 mins by fluorescence based assay
|
[PMID: 31505452]
|
|
Sf9
|
IC50 |
|
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
34.3 nM
Compound: Vorinostat
|
Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay
Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay
|
[PMID: 31391882]
|
|
Sf9
|
IC50 |
|
Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
Inhibition of full length recombinant human C-terminal FLAG-tagged HDAC1 expressed in sf9 cells preincubated for 5 mins followed by biotinylated H3K9-Ac substrate addition and measured after 60 mins by HTRF assay
|
[PMID: 30594434]
|
|
Sf9
|
IC50 |
|
Inhibition of His-tagged human HDAC11 expressed in Sf9 cells using Ac-Arg-Gly-Lys(Ac)-AMC as substrate by fluorometric assay
Inhibition of His-tagged human HDAC11 expressed in Sf9 cells using Ac-Arg-Gly-Lys(Ac)-AMC as substrate by fluorometric assay
|
[PMID: 27055940]
|
|
Sf9
|
IC50 |
|
Inhibition of full length recombinant FLAG/His-tagged C-terminal human HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
Inhibition of full length recombinant FLAG/His-tagged C-terminal human HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL (Z-Lys(Ac)-AMC) as substrate incubated for 90 mins by fluorescence based assay
|
[PMID: 31531206]
|
|
Sf9
|
IC50 |
|
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
|
[PMID: 31505452]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay
|
[PMID: 31505452]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant C-terminal His-tagged full length human HDAC3/NcoR2 complex expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
Inhibition of recombinant C-terminal His-tagged full length human HDAC3/NcoR2 complex expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC substrate 3 after 30 mins by fluorescence assay
|
[PMID: 25815139]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full-length human HDAC11 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
Inhibition of recombinant full-length human HDAC11 expressed in baculovirus infected Sf9 insect cells using 7-AMC-labelled HDAC substrate measured after 30 mins by fluorescence assay
|
[PMID: 30245394]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC class 2a substrate after 30 mins by fluorescence assay
Inhibition of recombinant C-terminal His-tagged full length human HDAC8 expressed in baculovirus infected insect Sf9 cells using fluorogenic HDAC class 2a substrate after 30 mins by fluorescence assay
|
[PMID: 25815139]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 17 hrs by electrophoretic mobility shift assay
Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 17 hrs by electrophoretic mobility shift assay
|
[PMID: 31938464]
|
|
Sf9
|
IC50 |
|
Inhibition of recombinant full length human HDAC4 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
Inhibition of recombinant full length human HDAC4 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence assay
|
[PMID: 30629434]
|
|
Sf9
|
IC50 |
> 10000 nM
Compound: SAHA
|
Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
> 10000 nM
Compound: SAHA
|
Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
> 10000 nM
Compound: SAHA
|
Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
> 10000 nM
Compound: SAHA
|
Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
Sf9
|
IC50 |
> 10000 nM
Compound: SAHA
|
Inhibition of recombinant full length human HDAC4 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
Inhibition of recombinant full length human HDAC4 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assay
|
[PMID: 31177073]
|
|
SiHa
|
IC50 |
4.34 μM
Compound: XII; SAHA
|
Antiproliferative activity against human SiHa cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human SiHa cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 38776806]
|
|
St-4
|
EC50 |
|
Inhibition of human St4 cells
Inhibition of human St4 cells
|
[PMID: 18247554]
|
|
St-4
|
EC50 |
5.2 μM
Compound: Suberoylanilide hydroxamic acid (SAHA)
|
Effective Concentration of compound to inhibit the growth of human St-4 cells
Effective Concentration of compound to inhibit the growth of human St-4 cells
|
[PMID: 15715470]
|
|
T-24
|
EC50 |
0.12 μM
Compound: SAHA, Zolinza
|
Induction of histone H3 acetylation in human T24 cells after 3 hrs by ELISA
Induction of histone H3 acetylation in human T24 cells after 3 hrs by ELISA
|
[PMID: 19084395]
|
|
T-24
|
EC50 |
0.25 μM
Compound: SAHA, Zolinza
|
Induction of alpha tubulin acetylation in human T24 cells after 3 hrs by ELISA
Induction of alpha tubulin acetylation in human T24 cells after 3 hrs by ELISA
|
[PMID: 19084395]
|
|
T-24
|
IC50 |
|
Antiproliferative activity against human T24 cells after 72 hrs by CellTiter blue-reagent based assay
Antiproliferative activity against human T24 cells after 72 hrs by CellTiter blue-reagent based assay
|
[PMID: 30645113]
|
|
T-cell
|
EC50 |
0.6 μM
Compound: SAHA, Vorinostat
|
Reactivation of latent HIV1 NL4-3-Luc expression in human naive CD4+ T cells treated 7 days post-infection measured after 48 hrs by luminescence plate reader analysis
Reactivation of latent HIV1 NL4-3-Luc expression in human naive CD4+ T cells treated 7 days post-infection measured after 48 hrs by luminescence plate reader analysis
|
[PMID: 24495105]
|
|
T47D
|
GI50 |
|
Antiproliferative activity against human T47D cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human T47D cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
T47D
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human T47D cells after 72 hrs by MTS assay
Growth inhibition of human T47D cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
T47D
|
IC50 |
|
Antiproliferative activity against human T47D cells after 72 hrs by MTT assay
Antiproliferative activity against human T47D cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
T47D
|
IC50 |
|
Antiproliferative activity against human T47D cells
Antiproliferative activity against human T47D cells
|
[PMID: 37652098]
|
|
T47D
|
IC50 |
|
Cytotoxicity against human T47D cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human T47D cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 32823005]
|
|
T47D
|
IC50 |
3.01 μM
Compound: Vorinostat
|
Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
|
[PMID: 29518312]
|
|
T47D
|
IC50 |
|
Antiproliferative activity against human T47D cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human T47D cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
TAMH
|
IC50 |
7.86 μM
Compound: 1; SAHA
|
Antiproliferative activity against mouse TAMH cells after 24 hrs by CellTiter-Glo assay
Antiproliferative activity against mouse TAMH cells after 24 hrs by CellTiter-Glo assay
|
[PMID: 27541357]
|
|
TAMH
|
IC50 |
|
Cytotoxicity against TAMH cells assessed as cell viability after 24 hrs by CellTiter-Glo assay
Cytotoxicity against TAMH cells assessed as cell viability after 24 hrs by CellTiter-Glo assay
|
[PMID: 28953386]
|
|
TE-1
|
IC50 |
|
Antiproliferative activity against human TE-1 cells assessed as inhibition of cell growth by MTT assay
Antiproliferative activity against human TE-1 cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 39102466]
|
|
THP-1
|
GI50 |
|
Growth inhibition of human THP-1 cells
Growth inhibition of human THP-1 cells
|
[PMID: 37429084]
|
|
THP-1
|
GI50 |
|
Growth inhibition of human THP-1 cells
Growth inhibition of human THP-1 cells
|
[PMID: 32320239]
|
|
THP-1
|
IC50 |
0.18 μM
Compound: Vorinostat
|
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37979441]
|
|
THP-1
|
IC50 |
|
Antileishmanial activity against amastigote stage of Leishmania donovani infected in human THP1 cells after 48 hrs by Alamar blue assay
Antileishmanial activity against amastigote stage of Leishmania donovani infected in human THP1 cells after 48 hrs by Alamar blue assay
|
[PMID: 25240614]
|
|
THP-1
|
IC50 |
|
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850]
|
|
THP-1
|
IC50 |
|
Antiproliferative activity against human THP-1 cells incubated for 24 to 48 hrs by CCK-8 assay
Antiproliferative activity against human THP-1 cells incubated for 24 to 48 hrs by CCK-8 assay
|
[PMID: 39145486]
|
|
THP-1
|
IC50 |
|
Cytotoxicity against human THP1 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human THP1 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 28368585]
|
|
THP-1
|
IC50 |
18 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against human THP1 cells assessed as reduction in cell viability
Cytotoxicity against human THP1 cells assessed as reduction in cell viability
|
[PMID: 26264503]
|
|
THP-1
|
IC50 |
|
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth incubated for 72 hrs by celltiter glo assay
|
[PMID: 37086699]
|
|
THP-1
|
IC50 |
|
Antiproliferative activity against human THP-1 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human THP-1 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
THP-1
|
IC50 |
|
Antiproliferative activity against human THP1 cells after 96 hrs by MTT assay
Antiproliferative activity against human THP1 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
THP-1
|
IC50 |
> 10 μg/mL
Compound: SAHA
|
Cytotoxicity against human THP1 cells after 48 hrs by Alamar blue assay
Cytotoxicity against human THP1 cells after 48 hrs by Alamar blue assay
|
[PMID: 25240614]
|
|
TK-10
|
GI50 |
0.63 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human TK10 cells after 72 hrs by MTS assay
Growth inhibition of human TK10 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
TPC1
|
IC50 |
3 μM
Compound: Vorinostat
|
Antiproliferative activity against human TPC1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human TPC1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
TSGH
|
IC50 |
2.09 μM
Compound: 1, SAHA, Vorinostat
|
Cytotoxicity against human TSGH cells by MTT assay
Cytotoxicity against human TSGH cells by MTT assay
|
[PMID: 24766560]
|
|
U-251
|
GI50 |
1.53 μM
Compound: Zolinza, NSC 701852
|
Cytotoxicity against human U251 cells after 48 hrs by SRB assay
Cytotoxicity against human U251 cells after 48 hrs by SRB assay
|
[PMID: 24015327]
|
|
U-251
|
GI50 |
|
Antiproliferative activity against human U251 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
Antiproliferative activity against human U251 cells assessed as cell growth inhibition measured after 48 hrs by SRB assay
|
[PMID: 32212730]
|
|
U-251
|
GI50 |
1.6 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human U251 cells after 72 hrs by MTS assay
Growth inhibition of human U251 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
U-251
|
GI50 |
|
Cytotoxicity against human U251 cells by MTT assay
Cytotoxicity against human U251 cells by MTT assay
|
[PMID: 23538115]
|
|
U-251
|
GI50 |
|
Cytotoxicity against human U251 cells after 48 hrs by MTT assay
Cytotoxicity against human U251 cells after 48 hrs by MTT assay
|
[PMID: 20605448]
|
|
U-251
|
IC50 |
1 μM
Compound: Vorinostat
|
Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay
Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay
|
[PMID: 30660827]
|
|
U-251
|
IC50 |
17.87 μM
Compound: 1; SAHA
|
Cytotoxicity against human TMZ-sensitive U251 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human TMZ-sensitive U251 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 35005974]
|
|
U-251
|
IC50 |
|
Cytotoxicity against human U-251 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human U-251 cells incubated for 72 hrs by MTT assay
|
[PMID: 38452727]
|
|
U-251
|
IC50 |
|
Antiproliferative activity against human U-251 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Antiproliferative activity against human U-251 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
|
[PMID: 37399711]
|
|
U-266
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
U-266
|
IC50 |
|
Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
|
[PMID: 31865013]
|
|
U-266
|
IC50 |
|
Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
|
[PMID: 28757101]
|
|
U-266
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human U-266 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
U-266
|
IC50 |
|
Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
U-266
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-266 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human U-266 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
U-266
|
IC50 |
|
Cytotoxicity against human U266 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human U266 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 26349626]
|
|
U-266
|
IC50 |
|
Antiproliferative activity against human U266 cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human U266 cells incubated for 48 hrs by MTT assay
|
[PMID: 32267687]
|
|
U-266
|
IC50 |
|
Growth inhibition of human U266 cells after 72 hrs by MTT assay
Growth inhibition of human U266 cells after 72 hrs by MTT assay
|
[PMID: 30594434]
|
|
U-266
|
IC50 |
|
Cytotoxicity against human U266 cells after 72 hrs by MTT assay
Cytotoxicity against human U266 cells after 72 hrs by MTT assay
|
[PMID: 26443078]
|
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U-87 MG cells incubated for 48 hrs by MTT assay
Antiproliferative activity against human U-87 MG cells incubated for 48 hrs by MTT assay
|
[PMID: 37563016]
|
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U87 cells after 96 hrs by MTT assay
Antiproliferative activity against human U87 cells after 96 hrs by MTT assay
|
[PMID: 31117517]
|
|
U-87MG ATCC
|
IC50 |
|
Cytotoxicity against human U87MG cells
Cytotoxicity against human U87MG cells
|
[PMID: 17691763]
|
|
U-87MG ATCC
|
IC50 |
15.71 μM
Compound: 1; SAHA
|
Antiproliferation activity against human U-87 MG cells assessed as growth inhibition measured after 1 hr by MTT assay
Antiproliferation activity against human U-87 MG cells assessed as growth inhibition measured after 1 hr by MTT assay
|
[PMID: 33744690]
|
|
U-87MG ATCC
|
IC50 |
15.71 μM
Compound: I; SAHA
|
Cytotoxicity against human U-87 MG cells assessed as inhibition of cell growth by MTT assay
Cytotoxicity against human U-87 MG cells assessed as inhibition of cell growth by MTT assay
|
[PMID: 36630883]
|
|
U-87MG ATCC
|
IC50 |
4.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 37875056]
|
|
U-87MG ATCC
|
IC50 |
|
Antiproliferative activity against human U-87 MG cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human U-87 MG cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
U-937
|
CC50 |
0.78 μM
Compound: Vorinostat
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Glo luminescent cell viability assay
Cytotoxicity against human U937 cells assessed as reduction in cell viability after 48 hrs by CellTiter-Glo luminescent cell viability assay
|
[PMID: 29541372]
|
|
U-937
|
CC50 |
|
Antiproliferative activity against human U937 cells after 72 hrs by celltiter-blue cell viability assay
Antiproliferative activity against human U937 cells after 72 hrs by celltiter-blue cell viability assay
|
[PMID: 19441846]
|
|
U-937
|
EC50 |
0.82 μM
Compound: 1a, SAHA
|
Antiproliferative activity against human U937 cells after 48 hrs by cell titer-glo assay
Antiproliferative activity against human U937 cells after 48 hrs by cell titer-glo assay
|
[PMID: 20218673]
|
|
U-937
|
EC50 |
|
Growth inhibition of human U937 cells after 44 hrs by MTT assay
Growth inhibition of human U937 cells after 44 hrs by MTT assay
|
[PMID: 28337317]
|
|
U-937
|
EC50 |
|
Cytotoxicity against human U937 cells assessed as decrease in cell viability after 44 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as decrease in cell viability after 44 hrs by MTT assay
|
[PMID: 29150330]
|
|
U-937
|
EC50 |
|
Compound was tested for anti-proliferative activity in U-937 human leukemia cell line
Compound was tested for anti-proliferative activity in U-937 human leukemia cell line
|
[PMID: 14698179]
|
|
U-937
|
GI50 |
1.42 μM
Compound: vorinostat, SAHA
|
Antiproliferative activity against human U937 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Antiproliferative activity against human U937 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 25218912]
|
|
U-937
|
GI50 |
|
Antiproliferative activity against human U937 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human U937 cells after 72 hrs by CCK8 assay
|
[PMID: 26331334]
|
|
U-937
|
GI50 |
|
Growth inhibition of human U937 cells after 72 hrs by SRB assay
Growth inhibition of human U937 cells after 72 hrs by SRB assay
|
[PMID: 20884208]
|
|
U-937
|
GI50 |
450 nM
Compound: SAHA, vorinostat
|
Antiproliferative activity against human U937 cells after 72 hrs by WST-1 assay
Antiproliferative activity against human U937 cells after 72 hrs by WST-1 assay
|
[PMID: 21080647]
|
|
U-937
|
IC50 |
0.19 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
U-937
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
U-937
|
IC50 |
0.37 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 26100440]
|
|
U-937
|
IC50 |
0.52 μM
Compound: 1; SAHA
|
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo luminescent assay
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo luminescent assay
|
[PMID: 38456618]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
|
[PMID: 28419930]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
Antiproliferative activity against human U937 cells after 72 hrs by MTT assay
|
[PMID: 28601509]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 29954683]
|
|
U-937
|
IC50 |
0.73 μM
Compound: 1; SAHA
|
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 3 days in presence of atamparib by celltiter-glo luminescent assay
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 3 days in presence of atamparib by celltiter-glo luminescent assay
|
[PMID: 38456618]
|
|
U-937
|
IC50 |
0.88 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Antiproliferative activity against human U-937 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37875056]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 25462271]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U-937 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Antiproliferative activity against human U-937 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
|
[PMID: 37660833]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U-937 cells assessed as cell growth inhibition after 72 hrs by CCK8 assay
Antiproliferative activity against human U-937 cells assessed as cell growth inhibition after 72 hrs by CCK8 assay
|
[PMID: 34454126]
|
|
U-937
|
IC50 |
1.24 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-937 cells measured after 72 hrs by CCK-8 assay
Antiproliferative activity against human U-937 cells measured after 72 hrs by CCK-8 assay
|
[PMID: 37875056]
|
|
U-937
|
IC50 |
1.41 μM
Compound: Vorinostat
|
Antiproliferative activity against human U-937 cells by MTT assay
Antiproliferative activity against human U-937 cells by MTT assay
|
[PMID: 37875056]
|
|
U-937
|
IC50 |
1.45 μM
Compound: SA, SAHA
|
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 24694055]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 29500131]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 30879863]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U-937 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay
Antiproliferative activity against human U-937 cells assessed as reduction in cell viability measured for 48 hrs by MTT assay
|
[PMID: 36996717]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
|
[PMID: 28757101]
|
|
U-937
|
IC50 |
100 μM
Compound: SAHA, Vorinostat
|
Cytotoxicity against human U937 cells assessed as reduction in cell viability
Cytotoxicity against human U937 cells assessed as reduction in cell viability
|
[PMID: 26264503]
|
|
U-937
|
IC50 |
|
Inhibition of human U937 cell proliferation after 48 hrs by MTT assay
Inhibition of human U937 cell proliferation after 48 hrs by MTT assay
|
[PMID: 23493449]
|
|
U-937
|
IC50 |
2.83 μM
Compound: SAHA, Zolinza
|
Antiproliferative activity against human U937 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
Antiproliferative activity against human U937 cells assessed as inhibition of cell growth after 72 hrs by MTT-based assay
|
[PMID: 25874326]
|
|
U-937
|
IC50 |
2.83 μM
Compound: Vorinostat
|
Antiproliferative activity against human U937 cells incubated for 72 hrs by MTT assay
Antiproliferative activity against human U937 cells incubated for 72 hrs by MTT assay
|
[PMID: 25953722]
|
|
U-937
|
IC50 |
|
Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 26349626]
|
|
U-937
|
IC50 |
|
Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
10.1039/C4MD00203B
|
|
U-937
|
IC50 |
4.82 μM
Compound: 1, SAHA
|
Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
|
[PMID: 26122774]
|
|
U-937
|
IC50 |
5.49 μM
Compound: 6, SAHA
|
Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human U937 cells assessed as growth inhibition after 48 hrs by MTT assay
|
[PMID: 25906087]
|
|
U-937
|
IC50 |
|
Antiproliferative activity against p53 null human U937 cells after 72 hrs by MTT assay
Antiproliferative activity against p53 null human U937 cells after 72 hrs by MTT assay
|
[PMID: 27505848]
|
|
U2932
|
IC50 |
|
Antiproliferative activity against human U2932 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human U2932 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
U2932
|
IC50 |
|
Antiproliferative activity against human U2932 cells after 72 hrs by MTT assay
Antiproliferative activity against human U2932 cells after 72 hrs by MTT assay
|
[PMID: 29150335]
|
|
U2OS
|
IC50 |
|
Anticancer activity against human U2OS cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
Anticancer activity against human U2OS cells assessed as cell growth inhibition incubated for 3 days by methylene blue staining based colorimetric assay
|
[PMID: 36244186]
|
|
U2OS
|
IC50 |
5.7 μM
Compound: Vorinostat
|
Cytotoxicity against human U2OS cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
Cytotoxicity against human U2OS cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
|
[PMID: 32791404]
|
|
UACC-257
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human UACC257 cells after 72 hrs by MTS assay
Growth inhibition of human UACC257 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
UACC-62
|
GI50 |
0.4 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human UACC62 cells after 72 hrs by MTS assay
Growth inhibition of human UACC62 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
UO-31
|
GI50 |
0.5 μM
Compound: SAHA, Zolinza
|
Growth inhibition of human UO31 cells after 72 hrs by MTS assay
Growth inhibition of human UO31 cells after 72 hrs by MTS assay
|
[PMID: 22435669]
|
|
Vero
|
EC50 |
|
Cytotoxicity against african green monkey Vero cells cells assessed as cell proliferation after 70 hrs by MTS assay
Cytotoxicity against african green monkey Vero cells cells assessed as cell proliferation after 70 hrs by MTS assay
|
[PMID: 25974739]
|
|
Vero
|
IC50 |
0.9 μM
Compound: SAHA, vorinostat
|
Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 72 hrs by MTT assay
Cytotoxicity against african green monkey Vero cells assessed as growth inhibition after 72 hrs by MTT assay
|
[PMID: 23786452]
|
|
Vero
|
IC50 |
|
Cytotoxicity against African green monkey Vero cells assessed as cell growth inhibition after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as cell growth inhibition after 72 hrs by MTT assay
|
[PMID: 28057407]
|
|
Vero
|
IC50 |
1.375 μg/mL
Compound: SAHA
|
Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS assay
|
[PMID: 20669972]
|
|
Vero
|
IC50 |
1.45 μM
Compound: 1; SAHA
|
Cytotoxicity against African green monkey Vero cells
Cytotoxicity against African green monkey Vero cells
|
[PMID: 33077264]
|
|
Vero
|
IC50 |
|
Cytotoxicity against African green monkey Vero cells
Cytotoxicity against African green monkey Vero cells
|
[PMID: 30245394]
|
|
Vero
|
IC50 |
1200 ng/mL
Compound: SAHA
|
Cytotoxicity against african green monkey Vero cells after 1 to 2 days by neutral red assay
Cytotoxicity against african green monkey Vero cells after 1 to 2 days by neutral red assay
|
[PMID: 19914074]
|
|
Vero
|
IC50 |
|
Antiproliferative activity against green monkey Vero cells assessed as inhibition of cell growth incubated for 3 to 5 days by CCK-8 assay
Antiproliferative activity against green monkey Vero cells assessed as inhibition of cell growth incubated for 3 to 5 days by CCK-8 assay
|
[PMID: 38367494]
|
|
Vero
|
IC50 |
261.6 ng/mL
Compound: SAHA
|
Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
|
[PMID: 19914074]
|
|
Vero
|
IC50 |
|
Antiproliferative activity against african green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTT assay
Antiproliferative activity against african green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTT assay
|
[PMID: 25993269]
|
|
Vero
|
IC50 |
|
Antiproliferative activity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Antiproliferative activity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
|
[PMID: 33965842]
|
|
Vero
|
IC50 |
|
Cytotoxicity against African Green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTS assay
Cytotoxicity against African Green monkey Vero cells assessed as inhibition of cell viability after 72 hrs by MTS assay
|
[PMID: 32061484]
|
|
Vero
|
IC50 |
478.9 ng/mL
Compound: SAHA
|
Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 infected in African green monkey (Cercopithecus aethiops) Vero cells assessed as parasite LDH activity after 72 hrs by Malstat reagent method
|
[PMID: 19914074]
|
|
WI-38
|
GI50 |
|
Antiproliferative activity against human WI38 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human WI38 cells after 72 hrs by CCK8 assay
|
[PMID: 26331334]
|
|
WI-38
|
IC50 |
10.07 μM
Compound: 1; SAHA
|
Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 36242988]
|
|
WI-38
|
IC50 |
|
Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
|
[PMID: 34628244]
|
|
WI-38
|
IC50 |
> 30 μM
Compound: SAHA; NSC759852
|
Cytotoxicity against human WI-38 cells assessed as reduction in cell survival incubated for 30 mins by methylene blue staining based analysis
Cytotoxicity against human WI-38 cells assessed as reduction in cell survival incubated for 30 mins by methylene blue staining based analysis
|
[PMID: 36306372]
|
|
YAC-1
|
IC50 |
0.199 μM
Compound: Vorinostat
|
Antiproliferative activity against mouse YAC-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
Antiproliferative activity against mouse YAC-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay
|
[PMID: 37875056]
|
|
Z-138
|
IC50 |
|
Antiproliferative activity against human Z138 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
Antiproliferative activity against human Z138 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay
|
[PMID: 34772529]
|
|
ZR-75-1
|
IC50 |
1629 nM
Compound: 1; SAHA
|
Antiproliferative activity against human ZR-75-1 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human ZR-75-1 cells assessed as reduction of cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 36934335]
|
|
ZR-75-1
|
IC50 |
6.86 μM
Compound: SAHA; 6
|
Antiproliferative activity against human ZR-75-1 cells incubated for 72 hrs by celltiter-glo luminescent assay
Antiproliferative activity against human ZR-75-1 cells incubated for 72 hrs by celltiter-glo luminescent assay
|
[PMID: 39178382]
|