Mn(II) protoporphyrin IX

Name: Mn(II) protoporphyrin IX
Brand: MedChemExpress
SKU: HY-136476A
Rating: 4.5 (1 reviews)

Cat. No.: HY-136476A: Data Sheet Handling Instructions
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Mn(II) protoporphyrin IX is a potential intravenous paramagnetic magnetic resonance contrast agent. Mn(II) protoporphyrin IX maintains strong paramagnetic properties.

For research use only. We do not sell to patients.

Mn(II) protoporphyrin IX Chemical Structure

CAS No. : 21393-64-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Mn(II) protoporphyrin IX:

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Biological Activity
Purity & Documentation
References
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Description

Mn(II) protoporphyrin IX is a potential intravenous paramagnetic magnetic resonance contrast agent. Mn(II) protoporphyrin IX maintains strong paramagnetic properties^[1].

In Vivo

Mn(II) protoporphyrin IX causes marked reduction of T1 in the liver, with less pronounced effects on other body tissues^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

615.58

Formula

C₃₄H₃₂MnN₄O₄

CAS No.

21393-64-6

Appearance

Solid

Color

Brown to black

SMILES

[O-]C(CCC(C1=CC(C(CCC([O-])=O)=C2C)=[N](C2=C3)[Mn+2]4([N-]5C3=C6C)[N-]1C7=CC(C(C=C)=C8C)=[N]4C8=CC5=C6C=C)=C7C)=O.[H+].[H+]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

1 M Ammonium hydroxide : 10 mg/mL (16.24 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6245 mL	8.1224 mL	16.2448 mL
5 mM	0.3249 mL	1.6245 mL	3.2490 mL
10 mM	0.1624 mL	0.8122 mL	1.6245 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jackson LS, et al. Manganese protoporphyrin IX. A potential intravenous paramagnetic NMR contrast agent: preliminary communication. Invest Radiol. 1985;20(2):226-229. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

1 M Ammonium hydroxide	1 mM	1.6245 mL	8.1224 mL	16.2448 mL	40.6121 mL
	5 mM	0.3249 mL	1.6245 mL	3.2490 mL	8.1224 mL
	10 mM	0.1624 mL	0.8122 mL	1.6245 mL	4.0612 mL
	15 mM	0.1083 mL	0.5415 mL	1.0830 mL	2.7075 mL