2. Vitamin D Related/Nuclear Receptor Epigenetics
  3. Androgen Receptor Epigenetic Reader Domain
  4. Antiproliferative agent-71

Antiproliferative agent-71 (Compound II-5) is an orally active dual inhibitor against the androgen receptor (AR) and bromodomain-containing protein 4 (BRD4). Antiproliferative agent-71 effectively inhibits tumor cell growth and proliferation by simultaneously blocking the functions of AR and BRD4. Antiproliferative agent-71 is promising for research of prostate cancer.

For research use only. We do not sell to patients.

Antiproliferative agent-71 Chemical Structure

Antiproliferative agent-71 Chemical Structure

CAS No. : 3083307-42-7

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Antiproliferative agent-71 Related Antibodies

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Description

Antiproliferative agent-71 (Compound II-5) is an orally active dual inhibitor against the androgen receptor (AR) and bromodomain-containing protein 4 (BRD4). Antiproliferative agent-71 effectively inhibits tumor cell growth and proliferation by simultaneously blocking the functions of AR and BRD4. Antiproliferative agent-71 is promising for research of prostate cancer[1].

IC50 & Target

BRD4

 

Molecular Weight

907.09

Formula

C50H54N10O5S
CAS No.
SMILES

N#CC1=C(OC)C=C(O[C@@H]2C(C)(C)[C@@H](NC(C3=CN=C(N4CCC5(CC(OC6=CC=C(C7=N[C@@H](CC8=NC=CO8)C9=NN=C(C)N9C%10=C7C(C)=C(C)S%10)C=C6)C5)CC4)N=C3)=O)C2(C)C)C=C1
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Purity & Documentation
References
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Antiproliferative agent-71 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiproliferative agent-713083307-42-7Antiproliferative agent71Antiproliferative agent 71Androgen ReceptorEpigenetic Reader DomainARBRD4tumor cellprostate cancerInhibitorinhibitorinhibit

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