2. Natural Products
  3. Plants Terpenoids
  4. Meliaceae Triterpenes
  5. Aglaia crassinervia Kurz ex Hiern
  6. Cabraleadiol

Cabraleadiol (3-Epiocotillol II) is isolated from the MeOH extract of the bark of Aglaia crassinervia.

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Cabraleadiol

Cabraleadiol Chemical Structure

CAS No. : 67253-01-4

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Based on 1 publication(s) in Google Scholar

Cabraleadiol Related Antibodies

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Description

Cabraleadiol (3-Epiocotillol II) is isolated from the MeOH extract of the bark of Aglaia crassinervia[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 50 μM
Compound: 15
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 24547740]
HepG2 IC50
> 50 μM
Compound: 15
Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 24547740]
MCF7 IC50
> 50 μM
Compound: 15
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 24547740]
RAW264.7 IC50
> 100 μM
Compound: 15
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay
[PMID: 24547740]
Molecular Weight

460.73

Formula

C30H52O3
CAS No.
SMILES

C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@]4(O[C@@H](CC4)C(C)(O)C)C)C)([H])[C@@]5([C@@](C(C)([C@@H](CC5)O)C)([H])CC1)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cabraleadiol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cabraleadiol67253-01-43-Epiocotillol IIOtherscabraleadiolMEOHAglaia crassinerviaInhibitorinhibitorinhibit

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HY-N2975
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