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Secretogranin-2 Protein, Human (HEK293, His)

Cat. No.: HY-P70134
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Secretogranin-2 Protein, a neuroendocrine member of the granin family, orchestrates the biogenesis of secretory granules, playing a pivotal role in their formation and maturation. It interacts with Secretogranin III/SCG3, highlighting its engagement in dynamic molecular networks crucial for finely tuned mechanisms in secretory granule development and function. Secretogranin-2 Protein, Human (HEK293, His) is the recombinant human-derived Secretogranin-2 protein, expressed by HEK293 , with C-6*His labeled tag.

For research use only. We do not sell to patients.

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Description

Secretogranin-2 Protein, a neuroendocrine member of the granin family, orchestrates the biogenesis of secretory granules, playing a pivotal role in their formation and maturation. It interacts with Secretogranin III/SCG3, highlighting its engagement in dynamic molecular networks crucial for finely tuned mechanisms in secretory granule development and function. Secretogranin-2 Protein, Human (HEK293, His) is the recombinant human-derived Secretogranin-2 protein, expressed by HEK293 , with C-6*His labeled tag.

Background

Secretogranin-2, a neuroendocrine protein belonging to the granin family, plays a pivotal role in orchestrating the biogenesis of secretory granules. Its regulatory influence is integral to the intricate processes governing the formation and maturation of these specialized cellular compartments. Notably, Secretogranin-2 engages in interactions with Secretogranin III/SCG3, underscoring its participation in dynamic molecular networks that contribute to the finely tuned mechanisms of secretory granule development and function.

Species

Human

Source

HEK293

Tag

C-6*His

Accession

P13521 (S29-M617)

Gene ID
Molecular Construction
N-term
Secretogranin-2 (S29-M617)
Accession # P13521
6*His
C-term
Synonyms
rHuSecretogranin-2/SCG2, His; Secretogranin-2; Chromogranin-C; Secretogranin II; SgII.
AA Sequence

SFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQAENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPLDSQSIYQLIEISRNLQIPPEDLIEMLKTGEKPNGSVEPERELDLPVDLDDISEADLDHPDLFQNRMLSKSGYPKTPGRAGTEALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPKAAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM

Molecular Weight

85-95 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Secretogranin-2 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Secretogranin-2 Protein, Human (HEK293, His)
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HY-P70134
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