2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. Cytokeratin 5/6 Antibody (YA5599)

Cytokeratin 5/6 Antibody (YA5599)

Cat. No.: HY-P85907
User Guide for Antibodies Technical Support

Cytokeratin 5/6 Antibody (YA5599) is a mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Cytokeratin 5/6. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human.

For research use only. We do not sell to patients.

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100 μL   Get quote  

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Cytokeratin 5/6 Antibody (YA5599) is a mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Cytokeratin 5/6. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human.
Background

CK5 is required for the formation of keratin intermediate filaments in the basal epidermis and maintains the skin barrier function in response to mechanical stress (by similarity). It potentially regulates the recruitment of Langerhans cells to the epidermis by modulating the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines, and CTNND1 localization in keratinocytes (by similarity).
Gene ID
SwissProt ID
Synonyms
58 kDa cytokeratin; CK-5; CK5; Cytokeratin-5; Cytokeratin5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K2C5_HUMAN; K5; keratin 5; epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types; Keratin 5; Keratin; keratin complex 2, basic, gene 5; keratin, type II cytoskeletal 5; Keratin-5; Keratin5; KRT 5; Krt5; KRT5A; type II cytoskeletal 5; Type-II keratin Kb5; CK 6A; CK 6B; CK 6C; CK 6D; CK 6E; CK-6B; CK-6C; CK-6E; Cytokeratin 6a; Cytokeratin 6B; Cytokeratin 6C; Cytokeratin 6D; Cytokeratin 6E; Cytokeratin-6B; Cytokeratin-6C; Cytokeratin-6E; K2C6C_HUMAN; K6a keratin; K6b keratin; K6C; K6c keratin; K6d keratin; K6e keratin; Keratin; Keratin K6h; Keratin type II cytoskeletal 6A; Keratin type II cytoskeletal 6B; Keratin type II cytoskeletal 6C; Keratin type II cytoskeletal 6D; Keratin type II cytoskeletal 6E; Keratin-6C; KRT6A; KRT6B; KRT6C; KRT6D; KRT6E; type II cytoskeletal 6C; Type-II keratin Kb12; 58 kDa Cytokeratin antibody; CK-5 antibody; CK5 antibody; Cytokeratin-5 antibody; Cytokeratin5 antibody; DDD antibody; DDD1 antibody; EBS2 antibody; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody; K2C5_HUMAN antibody; K5 antibody; keratin 5; epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types; antibody; Keratin 5 antibody; Keratin antibody; keratin complex 2, basic, gene 5 antibody; keratin, type II cytoskeletal 5 antibody; Keratin-5 antibody; Keratin5 antibody; KRT 5 antibody; Krt5 antibody; KRT5A antibody; type II cytoskeletal 5 antibody; Type-II keratin Kb5 antibody
Molecular Weight

Observed band size: 60,62 kDa
Purity

Protein G
Conjugation

Non-conjugated
Modification

Unmodified
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Mouse
Reactivity

Human
Dilution Ratio

IHC: 1:200-1000; WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:1000-5000
Application

IHC-P, WB, ICC/IF, ELISA
Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG2a
Immunogen

Synthesized peptide derived from human Cytokeratin 5 and Cytokeratin 6 AA range: C terminal amino acids 500-590 of Cytokeratin 5 and N terminal amino acids 2-100 of Cytokeratin 6
Documentation
User Guide for Antibodies (1077 KB)

Cytokeratin 5/6 Antibody (YA5599) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cytokeratin 5/6 Antibody (YA5599)
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