2. Vitamin D Related/Nuclear Receptor Others
  3. Androgen Receptor Isotope-Labeled Compounds
  4. Linuron-d6

Linuron-d6 is the deuterium labeled Linuron (HY-B1866). Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor.

For research use only. We do not sell to patients.

Linuron-d<sub>6</sub> Chemical Structure

Linuron-d6 Chemical Structure

CAS No. : 1219804-76-8

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Based on 1 publication(s) in Google Scholar

Other Forms of Linuron-d6:

Linuron-d6 Related Antibodies

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Description

Linuron-d6 is the deuterium labeled Linuron (HY-B1866). Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor[1][2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Linuron-d6 Related Antibodies
Molecular Weight

255.13

Formula

C9H4D6Cl2N2O2
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])ON(C([2H])([2H])[2H])C(NC1=CC(Cl)=C(C=C1)Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (391.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9196 mL 19.5979 mL 39.1957 mL
5 mM 0.7839 mL 3.9196 mL 7.8391 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9196 mL 19.5979 mL 39.1957 mL 97.9893 mL
5 mM 0.7839 mL 3.9196 mL 7.8391 mL 19.5979 mL
10 mM 0.3920 mL 1.9598 mL 3.9196 mL 9.7989 mL
15 mM 0.2613 mL 1.3065 mL 2.6130 mL 6.5326 mL
20 mM 0.1960 mL 0.9799 mL 1.9598 mL 4.8995 mL
25 mM 0.1568 mL 0.7839 mL 1.5678 mL 3.9196 mL
30 mM 0.1307 mL 0.6533 mL 1.3065 mL 3.2663 mL
40 mM 0.0980 mL 0.4899 mL 0.9799 mL 2.4497 mL
50 mM 0.0784 mL 0.3920 mL 0.7839 mL 1.9598 mL
60 mM 0.0653 mL 0.3266 mL 0.6533 mL 1.6332 mL
80 mM 0.0490 mL 0.2450 mL 0.4899 mL 1.2249 mL
100 mM 0.0392 mL 0.1960 mL 0.3920 mL 0.9799 mL
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Linuron-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Linuron-d61219804-76-8Androgen ReceptorIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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HY-B1866S
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