2. Natural Products
  3. Plants Terpenoids
  4. Leguminosae Labiatae Diterpenoids
  5. Samanea saman (Jacq.) Merr.
  6. Dihydroisotanshinone II

Dihydroisotanshinone II is a Diterpenoids product that can be isolated from the roots of Salvia miltiorrhiza.

For research use only. We do not sell to patients.

Dihydroisotanshinone II

Dihydroisotanshinone II Chemical Structure

CAS No. : 260397-58-8

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Dihydroisotanshinone II Related Antibodies

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Description

Dihydroisotanshinone II is a Diterpenoids product that can be isolated from the roots of Salvia miltiorrhiza[1].

Cellular Effect
Cell Line Type Value Description References
AGS IC50
> 20 μM
Compound: 8, dihydroisotanshinone ii
Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
[PMID: 17583950]
AGS IC50
> 50 μM
Compound: 8, dihydroisotanshinone ii
Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay
Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay
[PMID: 17583950]
Hep 3B2 IC50
> 20 μM
Compound: 8, dihydroisotanshinone ii
Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
[PMID: 17583950]
Hep 3B2 IC50
> 50 μM
Compound: 8, dihydroisotanshinone ii
Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay
Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay
[PMID: 17583950]
Molecular Weight

278.30

Formula

C18H14O3
CAS No.
SMILES

O=C1C2=C(C3=CC=CC(C)=C3C=C2)C4=C([C@@H](CO4)C)C1=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Dihydroisotanshinone II Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydroisotanshinone II260397-58-8OthersInhibitorinhibitorinhibit

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Dihydroisotanshinone II
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HY-N8674
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