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  4. Leguminosae

Leguminosae

 

Leguminosae (884):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1756
    Rotenone 83-79-4 99.74%
    Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.
    Rotenone
  • HY-18085
    Quercetin 117-39-5 99.80%
    Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.
    Quercetin
  • HY-14596
    Genistein 446-72-0 99.82%
    Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
    Genistein
  • HY-N0750
    Monocrotaline 315-22-0 99.96%
    Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid. Monocrotaline inhibits OCT-1 and OCT-2 with IC50s of 36.8 µM and 1.8 mM, respectively. Monocrotaline has antitumor activity and is cytotoxic to hepatocellular carcinoma cells. Monocrotaline is used to induce a model of pulmonary hypertension in rodents. [2][6][8].
    Monocrotaline
  • HY-N0184
    Glycyrrhizic acid 1405-86-3 99.84%
    Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.
    Glycyrrhizic acid
  • HY-N6020R
    (-)-Butin (Standard) 492-14-8
    (-)-Butin (Standard) is the analytical standard of (-)-Butin (HY-N6020). This product is intended for research and analytical applications. (-)-Butin is a enantiomer of Butin (HY-N6020B). Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities.
    (-)-Butin (Standard)
  • HY-N6020AR
    (+)-Butin (Standard) 74628-42-5
    (+)-Butin (Standard) is the analytical standard of (+)-Butin (HY-N6020A). This product is intended for research and analytical applications. (+)-Butin is the R-enantiomer of Butin (HY-N6020B). Butin is a bioactive flavonoid. Butin can be isolated from the heartwood of Dalbergia cocos. Butin exhibits potent antioxidant, antiplatelet, and anti-inflammatory activities.
    (+)-Butin (Standard)
  • HY-N11759
    2′-Hydroxydihydrodaidzein 94388-77-9
    2′-Hydroxydihydrodaidzein is an isoflavonoid phytoalexin that can be extacted from the Fungus-inoculated Leaflets of Erythrina Species. 2′-Hydroxydihydrodaidzein has antioxidant acitivity.
    2′-Hydroxydihydrodaidzein
  • HY-N0171A
    Beta-Sitosterol (purity>98%) 83-46-5 99.74%
    Beta-Sitosterol (purity>98%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc.
    Beta-Sitosterol (purity>98%)
  • HY-N0431
    Astragaloside IV 84687-43-4 99.93%
    Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
    Astragaloside IV
  • HY-N0148
    Rutin 153-18-4 98.09%
    Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress.
    Rutin
  • HY-N7038
    Phytohemagglutinin 9008-97-3
    Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β.
    Phytohemagglutinin
  • HY-N0145
    Puerarin 3681-99-0 98.92%
    Puerarin is an isoflavone extracted from Pueraria root and is a 5-HT2C receptor antagonist. Puerarin inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which in turn leads to decreased fat absorption.
    Puerarin
  • HY-13715A
    Norepinephrine hydrochloride 329-56-6 99.95%
    Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors.
    Norepinephrine hydrochloride
  • HY-N0183
    Formononetin 485-72-3 98.99%
    Formononetin is a potent FGFR2 inhibitor with an IC50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth.
    Formononetin
  • HY-N0100
    Naringenin 480-41-1 99.28%
    Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
    Naringenin
  • HY-N0019
    Daidzein 486-66-8 99.72%
    Daidzein is a soy isoflavone, which acts as a PPAR activator.
    Daidzein
  • HY-N0102
    Isoliquiritigenin 961-29-5 98.07%
    Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM.
    Isoliquiritigenin
  • HY-N0776
    Isorhamnetin 480-19-3 99.94%
    Isorhamnetin is a flavonoid compound extracted from the Chinese herb Hippophae rhamnoides L.. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3K.
    Isorhamnetin
  • HY-N0018
    Daidzin 552-66-9 99.77%
    Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption.
    Daidzin