Phospholipase C gamma 1 Antibody (YA3851)

Cat. No.: HY-P84154: Data Sheet User Guide for Antibodies
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Phospholipase C gamma 1 Antibody (YA3851) is a mouse-derived and non-conjugated IgG1 antibody, targeting to PLCG1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

Biological Activity
Technical Parameters
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Description	Phospholipase C gamma 1 Antibody (YA3851) is a mouse-derived and non-conjugated IgG1 antibody, targeting to PLCG1. It can be applicated for WB, IHC-P, ICC/IF, FC, ELISA assays, in the background of human, mouse.
Background	Phospholipase C gamma 1 (PLCγ1) mediates the production of second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3), playing a crucial role in regulating intracellular signaling cascades. It becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3, and FGFR4 (By similarity). PLCγ1 is involved in actin reorganization and cell migration. Additionally, it acts as a guanine nucleotide exchange factor, binding to the GTPase DNM1 and catalyzing GDP dissociation to facilitate GTP binding, thereby enhancing DNM1-dependent endocytosis (By similarity).
Gene ID	5335 [NCBI]
SwissProt ID	P19174
Synonyms	PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
Molecular Weight	Predicted band size: 149 kDa; Observed band size: 149 kDa
Purity	affinity purified.
Conjugation	Non-conjugated
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse
Dilution Ratio	WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000
Application	WB, IHC-P, ICC/IF, FC, ELISA
Appearance	Liquid
Formulation	Supplied in PBS with 0.05% sodium azide
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG1
Immunogen	Purified recombinant fragment of human PLCG1 (AA: 1192-1291) expressed in E. Coli.
Documentation	Data Sheet (234 KB) User Guide for Antibodies (1077 KB)

Phospholipase C gamma 1 Antibody (YA3851) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospholipase C gamma 1 Antibody (YA3851)

Biological Activity

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Phospholipase C gamma 1 Antibody (YA3851) Related Classifications

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