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ALA

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2502

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

2756

Peptides

101

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Recombinant Proteins

Isotope-Labeled Compounds

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Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010162

*H-Ala-Ala-OH* L-ALAnyl-L-ALAnine; ALA-ALA	Amino Acid Derivatives	Others
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-N0728A

α-Linolenic acid sodium ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3	Akt PI3K	Cardiovascular Disease Cancer
α-Linolenic acid sodium, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid sodium can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid sodium possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-P4527

Ala-Ala-βNA	Prolyl Endopeptidase (PREP)	Others
Ala-Ala-βNA is a dipeptidyl-fl-naphthylamide (βNA). Ala-Ala-βNA is readily hydrolyzed, with optimum hydrolysis pH of 8.5-9.0 .

HY-137164A

Ala-Ala-Phe-AMC TFA	Fluorescent Dye	Others
Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .

HY-W013460

**Ala-Ala-Ala**	Amino Acid Derivatives	Others
Ala-Ala-Ala is an alanine derivative .

HY-W010162R

*H-Ala-Ala-OH (Standard)* L-ALAnyl-L-ALAnine (Standard); ALA-ALA (Standard)	Amino Acid Derivatives Reference Standards	Others
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) (Standard) is the analytical standard of H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala). This product is intended for research and analytical applications. H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-P3558

Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met	Amino Acid Derivatives	Others
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met

HY-165153

Ala-D-γ-Glu-Lys-D-Ala-D-Ala TFA A0910 TFA; ALA-D-isoGlu-Lys-D-ALA-D-ALA TFA	Endogenous Metabolite	Others
Ala-D-γ-Glu-Lys-D-Ala-D-Ala TFA is the pentapeptide tail of the peptidoglycan precursor UDPMurNAc-l-Ala-γ-d-Glu-l-Lys(Gly)(5)-d-Ala-d-Ala .

HY-P10471B

Ala-MPSD	MARCKS PKC	Others
Ala-MPSD is a control peptide for MPSD (HY-P10471). In Ala-MPSD, the four serine residues of MPSD are substituted by alanines .

HY-129360

Ala-Ala-Asn-PAB	ADC Linker	Cancer
Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) .

HY-P3162

*(Ala13)-Apelin-13*	Apelin Receptor (APJ)	Cardiovascular Disease
(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway .

HY-137164

Ala-Ala-Phe-AMC	Endogenous Metabolite	Others
Ala-Ala-Phe-AMC serves as a fluorogenic substrate that exhibits positively charged properties, making it suitable for assessing proteolytic activity.

HY-129360A

Ala-Ala-Asn-PAB TFA	ADC Linker	Cancer
Ala-Ala-Asn-PAB TFA is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) .

HY-P4464

Ala-Phe-Pro-pNA	Ser/Thr Protease	Cancer
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .

HY-P5896

Ala5-Galanin (2-11)	Neuropeptide Y Receptor	Neurological Disease
Ala5-Galanin (2-11) is a galanin receptor 2 (GAL₂R) specific agonist with a K_i of 258 nM .

HY-P4528

Ala-Phe-Pro-βNA	Ser/Thr Protease	Others
Ala-Phe-Pro-βNA is the subsrate of prolyl tripeptidyl aminopeptidase, which is from Porphyromonas gingivalis. Ala-Phe-Pro-βNA binds to H-Ala-Ile-pyrrolidin-2-yl boronic acid for PTP39 and the E636A mutant with K_i values of 88.1 nM and 48.8 nM, respectivley .

HY-P3648

Ala-Ala-Pro-Val-chloromethylketone AAPV-CMK	Elastase	Inflammation/Immunology
Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases .

HY-129407

AAF-CMK TFA ALA-ALA-phe-chloromethylketone tfa; N-ALA-ALA-Phe-CMK; Tripeptidyl Peptidase inhibitor II	Proteasome	Infection
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

HY-N5203

Ala0-Actagardine	Antibiotic Bacterial	Infection
Ala0-Actagardine is a lantibiotic found in the cultures of Actinoplanes liguriae ATCC 31048 .

HY-P4464A

Ala-Phe-Pro-pNA TFA	Ser/Thr Protease	Cancer
Ala-Phe-Pro-pNA TFA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA TFA can be used to test tripeptidyl peptidase activity .

HY-P3162A

*(Ala13)-Apelin-13 TFA*	Apelin Receptor (APJ)	Cardiovascular Disease
(Ala13)-Apelin-13 TFA is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 TFA inhibits gastric motility through vagal cholinergic pathway .

HY-P4339

Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Ala-Phe-Lys-AMC is a fluorogenic substrate, which can be used for residual plasmin activity assay .

HY-P10711

ALA-A2 peptide	Autophagy	Cancer
ALA-A2 is an anticancer peptide discovered in alpha-lactalbumin that selectively kills cancer cells by inducing Autophagy. ALA-A2 has cell-penetrating capabilities, allowing it to effectively enter cells without relying on membranolytic effects. In A549 lung cancer cells, ALA-A2 demonstrates significant dose-dependent anticancer activity. ALA-A2 holds promise for research in cancer therapy and autophagy regulation .

HY-145367

Ala-CO-amide-C4-Boc	ADC Linker	Cancer
Ala-CO-amide-C4-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P5372

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-P5372A

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA	Protease Activated Receptor (PAR)	Cancer
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .

HY-137901

L-Alanine 4-nitroanilide hydrochloride, 99% ALA-4-nitroanilide, 99%; H-ALA-pNA, 99%	Biochemical Assay Reagents	Others
L-Alanine 4-nitroanilide hydrochloride, 99% is a detection substrate for L-alanine aminopeptidase.

HY-166997

AL-A12	Liposome	Others
AL-A12 is a short-chain amino lipid with high gene delivery efficiency and low toxicity, and can be used in drug delivery research .

HY-W012161

Alanylphenylalanine L-ALAnyl-L-phenylALAnine; H-ALA-Phe-OH	Endogenous Metabolite	Cancer
Alanylphenylalanine is a potential antitumor agent that targets DNA via metal coordination. The complex of Alanylphenylalanine and Au (III) can bind to DNA and inhibit tumor cell proliferation[1][2].

HY-N6708

Alamethicin 1 Publications Verification	Antibiotic Bacterial	Infection
Alamethicin is a linear 20-amino acid antibiotic, which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic α-helical structure in biological membranes .

HY-P2098

Alamethicin F 50	Antibiotic Bacterial Fungal	Infection
Alamethicin F 50 is an antibiotic. Alamethicin F 50 is composed of membrane-active peptide, containing 75% Alamethicin F 50/5 and 10% Alamethicin F 50/7. Alamethicin F 50 is exhibits antifungal and antibacterial activity by disrupting the integrity of microbial cell membranes, resulting in leakage of cell contents and death of the microorganisms. Alamethicin F 50 is able to reduce the surface tension of water, which can be used as a surfactant or detergent .

HY-P3108

Alamandine 1 Publications Verification	Angiotensin Receptor Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Alamandine, a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine targets to protect the kidney and heart through anti-hypertensive actions .

HY-W336442

*H-His-Ala-OH* L-histidyl-L-ALAnine	Biochemical Assay Reagents	Others
H-His-Ala-OH is a dipeptide -type substrate that can be utilized in biochemical assay .

HY-P4353

*D-{Ala-Ala-Ala}*	Bacterial	Others
D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations .

HY-P4350

*Suc-Ala-Ala-Ala-AMC*	Elastase	Others
Suc-Ala-Ala-Ala-AMC is a peptide substrate of elastase or elastase-like .

HY-136626

*Z-Ala-Ala-Asn-AMC* 3 Publications Verification Cbz-ALA-ALA-Asn-AMC	Fluorescent Dye	Cancer
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .

HY-P4706

*Boc-Ala-Ala-pNA*	Amino Acid Derivatives	Others
Boc-Ala-Ala-pNA is a serine peptidase

HY-P4453

*Boc-Ala-Ala-Asp-pNA*	Caspase	Cancer
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .

HY-P4126

*Suc-Ala-Ala-Pro-Val-AMC*	Elastase	Others
Suc-Ala-Ala-Pro-Val-AMC, a tetrapeptide, is an elastasesubstrate. Suc-Ala-Ala-Pro-Val-AMC can be used for determining elastase activity .

HY-P4362

*Suc-Ala-Pro-Ala-AMC*	Elastase	Others
Suc-Ala-Pro-Ala-AMC is a tripeptide substrate of elastase .

HY-P4549

*H-D-Ala-D-Ala-D-Ala-D-Ala-OH*	Aminopeptidase	Others
H-D-Ala-D-Ala-D-Ala-D-Ala-OH is a substrate for D-aminopeptidase .

HY-P10004

*Z-Ala-Ala-Asp-CMK* 1 Publications Verification Z-AAD-CMK	Caspase Apoptosis Reactive Oxygen Species (ROS) Interleukin Related	Inflammation/Immunology Cancer
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer .

HY-P3106

*(Z-Ala-Ala-Ala-Ala)2Rh110* (Z-ALA-ALA-ALA-ALA)2Rhodamine110; bis-CBZ-L-ALAnyl-L-arginine amide Rhodamine 110	Fluorescent Dye	Others
(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.

HY-136705

*MeO-Suc-Ala-Ala-Pro-Ala-CMK* MSACK	Elastase	Inflammation/Immunology
MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE), with an IC₅₀ of 20.3 μM. MeO-Suc-Ala-Ala-Pro-Ala-CMK can inhibit the hydrolysis of substrates such as elastin in lung tissue by HNE. MeO-Suc-Ala-Ala-Pro-Ala-CMK can be used in the research of related diseases such as chronic obstructive pulmonary disease (COPD) .

HY-W015450R

*D-Ala-D-Ala* (Standard)**	Reference Standards Endogenous Metabolite	Others
D-Ala-D-Ala (Standard) is the analytical standard of D-Ala-D-Ala. This product is intended for research and analytical applications. D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase .

HY-W015450

D-Ala-D-Ala	Endogenous Metabolite	Others
D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase .

HY-148463

*MP-Ala-Ala-PAB*	ADC Linker	Cancer
MP-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-148462

*Fmoc-Ala-Ala-PAB*	ADC Linker	Cancer
Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-148464

*MC-Ala-Ala-PAB*	ADC Linker	Cancer
MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P4346

*MeOSuc-Ala-Ala-Pro-Met-AMC*	Elastase	Others
MeOSuc-Ala-Ala-Pro-Met-AMC is a peptide substrate of elastases and chymotrypsin-like serine peptidases .

Cat. No.	Product Name	Type

HY-P2685

*MeOSuc-Ala-Ala-Pro-Val-pNA*	Chromogenic Substrates
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

HY-134432B

*Boc-Gln-Ala-Arg-AMC acetate*	Dyes
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-111956B

*D-Ala-Lys-AMCA hydrochloride* 1 Publications Verification	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .

HY-P4202

*Suc-Ala-Glu-Pro-Phe-pNA* Suc-AEPF-pNA	Chromogenic Substrates
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-P2536

*Mca-Ala-Pro-Lys(Dnp)-OH*	Fluorescent Dyes/Probes
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .

HY-P3120

*Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2*	Chromogenic Substrates
Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).

HY-111956

*D-Ala-Lys-AMCA*	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .

HY-111956A

*D-Ala-Lys-AMCA TFA*	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm) .

HY-137928

*H-Ala-4MβNA hydrochloride*	Fluorescent Dyes/Probes
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .

HY-P4202A

*Suc-Ala-Glu-Pro-Phe-pNA TFA* Suc-AEPF-pNA TFA	Chromogenic Substrates
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-D1154

β-Ala-Lys(AMCA)

Dyes

β-Ala-Lys(AMCA) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-P3749

*Mca-(ala7,lys(dnp)9)-bradykinin*	Fluorescent Dyes/Probes
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .

HY-131498

MOCAc-PLGL(Dpa)AR Mca-Pro-Leu-Gly-Leu-Dpa-ALA-Arg-NH2	Fluorescent Dyes/Probes
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2), MMP-7 and MMP-9. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues .

HY-P1363F3

5-FAM-β-Amyloid (1-42), human Tris 5-FAM-Amyloid β-peptide (1-42) (human) Tris	Fluorescent Dyes/Probes
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).

HY-P0136AF

FAM-SAMS TFA	Dyes
FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .

Cat. No.	Product Name	Type

HY-W010162

*H-Ala-Ala-OH* L-ALAnyl-L-ALAnine; ALA-ALA	Cell Assay Reagents
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-Y0973

BOP hexafluorophosphate	Biochemical Assay Reagents
BOP (hexafluorophosphate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. BOP hexafluorophosphate can be used in stepwise solid phase synthesis to prepare fragments of [Ala ¹⁵]-GRF(1-29)-NH₂ .

HY-P5282

ApoA-I mimetic peptide	Drug Delivery
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) is an ApoA-I mimetic peptide. ApoA-I mimetic peptide has good phosphatidylcholine: cholesterol acyltransferase (LCAT) activation activity. ApoA-I mimetic peptide can be used to synthesize peptide/lipid complexes. ApoA-I mimetic peptide can be used in atherosclerosis research.

HY-W010162R

H-Ala-Ala-OH (Standard)

L-ALAnyl-L-ALAnine (Standard); ALA-ALA (Standard)

Cell Assay Reagents

H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) (Standard) is the analytical standard of H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala). This product is intended for research and analytical applications. H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-137164

Ala-Ala-Phe-AMC	Biochemical Assay Reagents
Ala-Ala-Phe-AMC serves as a fluorogenic substrate that exhibits positively charged properties, making it suitable for assessing proteolytic activity.

HY-137901

L-Alanine 4-nitroanilide hydrochloride, 99% ALA-4-nitroanilide, 99%; H-ALA-pNA, 99%	Carbohydrates
L-Alanine 4-nitroanilide hydrochloride, 99% is a detection substrate for L-alanine aminopeptidase.

HY-166997

AL-A12	Drug Delivery
AL-A12 is a short-chain amino lipid with high gene delivery efficiency and low toxicity, and can be used in drug delivery research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W012161

Alanylphenylalanine L-ALAnyl-L-phenylALAnine; H-ALA-Phe-OH	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Alanylphenylalanine is a potential antitumor agent that targets DNA via metal coordination. The complex of Alanylphenylalanine and Au (III) can bind to DNA and inhibit tumor cell proliferation[1][2].

HY-N6708

Alamethicin 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Source classification Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Alamethicin is a linear 20-amino acid antibiotic, which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic α-helical structure in biological membranes .

HY-W015450R

*D-Ala-D-Ala* (Standard)**	Natural Products Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
D-Ala-D-Ala (Standard) is the analytical standard of D-Ala-D-Ala. This product is intended for research and analytical applications. D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase .

HY-W015450

D-Ala-D-Ala	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase .

HY-133100

*5-ALA* benzyl ester hydrochloride** Benzyl-ALA hydrochloride	Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .

HY-W004066

*Ac-Ala-OH*	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Ser/Thr Protease
Ac-Ala-OH is an endogenous metabolite. Ac-ALA-OH inhibits APEH. Ac-Ala-OH can be used in breast cancer research .

HY-W004066R

*Ac-Ala-OH (Standard)*	Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Ser/Thr Protease
Ac-Ala-OH (Standard) is an analytical standard for Ac-Ala-OH. This product is intended for use in research and analytical applications. Ac-Ala-OH is an endogenous metabolite. Ac-ALA-OH inhibits APEH. Ac-Ala-OH is useful in breast cancer research .

HY-N9251

*Cyclo(Ile-Ala)* 1 Publications Verification	Alkaloids Microorganisms Classification of Application Fields Other Alkaloids Marine natural products Source classification Other Diseases Marine microorganism Disease Research Fields	Others
Cyclo(Ile-Ala) is found in marine actinomycete 11014 I. .

HY-N5203

Ala0-Actagardine	Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Ala0-Actagardine is a lantibiotic found in the cultures of Actinoplanes liguriae ATCC 31048 .

HY-P1935

*Cyclo(Ala-Pro)*	Alkaloids Microorganisms Other Alkaloids Source classification	Biochemical Assay Reagents
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-N7132

(-)-Menthyl acetate L-Menthyl acetate	Natural Products Classification of Application Fields Acacia farnesiana (Linn.) Willd. Labiatae Source classification Other Diseases Plants Disease Research Fields	Others
(-)-Menthyl acetate (L-Menthyl acetate) is a derivative of L-menthol. (-)-Menthyl acetate is effective to enhance 5-aminolevulinic acid (ALA) skin permeation .

HY-N13432

*Cyclo(Ala-Phe)*	Natural Products Rubia schumanniana E. Pritz. Source classification Rubiaceae Plants	Others
Cyclo(Ala-Phe) is a natural product .

HY-75564R

*Cyclo(Ala-Gly) (Standard)*	Natural Products Microorganisms Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Cyclo(Ala-Gly) (Standard) is the analytical standard of Cyclo(Ala-Gly). This product is intended for research and analytical applications. Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC50 values range from 9.5 to 18.1 μM[1].

HY-N10185

*Cyclo(D-Ala-L-Pro)*	Microorganisms Classification of Application Fields Cyclopeptides Source classification Other Diseases Disease Research Fields	Others
Cyclo(D-Ala-L-Pro) is a cyclodipeptide .

HY-W007035R

*H-Val-Ala-OH (Standard)*	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Amino Acid Derivatives
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .

HY-N7132R

(-)-Menthyl acetate (Standard) L-Menthyl acetate (Standard)	Natural Products Acacia farnesiana (Linn.) Willd. Labiatae Source classification Plants	Reference Standards Others
(-)-Menthyl acetate (Standard) is the analytical standard of Menthyl acetate. This product is intended for research and analytical applications. (-)-Menthyl acetate (L-Menthyl acetate) is a derivative of L-menthol. (-)-Menthyl acetate is effective to enhance 5-aminolevulinic acid (ALA) skin permeation .

HY-75564

*Cyclo(Ala-Gly)*	Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC₅₀ values range from 9.5 to 18.1 μM .

HY-W007035

*H-Val-Ala-OH* 1 Publications Verification Valyl-ALAnine	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Amino Acid Derivatives
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. H-Val-Ala-OH has a role as a metabolite and also has a bitter taste .

HY-W009602

Phenylalanylalanine Phe-ALA	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Neprilysin
Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism .

HY-N0305

5-Aminolevulinic acid hydrochloride 15+ Cited Publications 5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer	Autophagy Mitophagy Endogenous Metabolite Apoptosis
5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-W000450

5-Aminolevulinic acid 15+ Cited Publications 5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid	Cardiovascular Disease Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Amino acids Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-66007

*Ac-β-Ala-OH*	Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Ac-β-Ala-OH (N-Acetyl-β-alanine), an abnormal amino acid metabolite, is a mono-N-protected amino acid (MPAA) ligand .

HY-W971376

*Cyclo(Ala-Tyr)*	Alkaloids Microorganisms Other Alkaloids Source classification	Others
Cyclo(Ala-Tyr) is a cyclic dipeptide that can be isolated from the fermentation broth of the marine microorganism Bacillus marinus B-9987 isolated from the rhizosphere tissue of Suaeda salsa in the intertidal zone of Bohai Bay, China .

HY-112171

γ-L-Glutamyl-L-alanine 1 Publications Verification γ-Glu-ALA	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite CaSR
γ-L-Glutamyl-L-alanine (γ-Glu-Ala), composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .

HY-N9251R

*Cyclo(Ile-Ala) (Standard)*	Alkaloids Microorganisms Other Alkaloids Marine natural products Source classification Marine microorganism	Reference Standards Others
Isoferulic acid (Standard) is the analytical standard of Isoferulic acid. This product is intended for research and analytical applications. Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Isoferulic acid also has anti-influenza virus activities.

HY-W009602R

Phenylalanylalanine (Standard)	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Neprilysin
Phenylalanylalanine (H-Phe-Ala-OH) is a dipeptide composed of phenylalanine and alanine. Phenylalanylalanine is an incomplete breakdown product of protein digestion or protein catabolism .

HY-W040088

L-Alanyl-L-leucine H-ALA-Leu-OH	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Alanyl-L-leucine is an endogenous metabolite.

HY-N0196A

Baicalein hydrate 5,6,7-Trihydroxyflavone hydrate	Flavonoids Labiatae Flavonones Source classification Plants Medicago truncatula Gaertn.	Influenza Virus Ferroptosis Xanthine Oxidase
Baicalein hydrate (ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3) is a xanthine oxidase inhibitor with an IC₅₀ value of 3.12 μM.

HY-B1247

Protoporphyrin IX 15+ Cited Publications	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-112171R

γ-L-Glutamyl-L-alanine (Standard) γ-Glu-ALA (Standard)	Natural Products Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Endogenous Metabolite CaSR
γ-L-Glutamyl-L-alanine (Standard) is the analytical standard of γ-L-Glutamyl-L-alanine. This product is intended for research and analytical applications. γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .

HY-W014394R

Vanillyl butyl ether (Standard)	Monophenols other families Source classification Phenols Plants	TRP Channel Reference Standards Parasite
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-B1247R

Protoporphyrin IX (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-148285

Succinyl CoA Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Succinyl CoA is an intermediate of the citric acid cycle. Succinyl CoA can be converted to succinic acid and can also combines with glycine to form δ-amino levulinic acid (ALA) to synthesize porphyrins (heme). Succinyl CoA can be used in the study of metabolic, neurological and haematological abnormalities (such as porphyrias) caused by nutritional vitamin B12 deficiency (resulting in a deficiency in Succinyl CoA synthesis) .

HY-137808

Succinyl-Coenzyme A sodium 2 Publications Verification Succinyl-CoA sodium	Natural Products Neurological Disease Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Succinyl-Coenzyme A (Succinyl-CoA) sodium is an intermediate of the citric acid cycle. Succinyl-Coenzyme A sodium can be converted to succinic acid and can also combines with glycine to form δ-ALA to synthesize porphyrins (heme). Succinyl-Coenzyme A sodium can be used in the study of metabolic, neurological and haematological abnormalities (such as porphyrias) caused by nutritional vitamin B₁₂ deficiency (resulting in a deficiency in Succinyl-Coenzyme A synthesis) .

HY-N0305R

5-Aminolevulinic acid hydrochloride (Standard) 10+ Cited Publications 5-ALA hydrochloride (Standard); δ-Aminolevulinic acid hydrochloride (Standard); 5-Amino-4-oxopentanoic acid hydrochloride (Standard)	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Autophagy Endogenous Metabolite Apoptosis Mitophagy Reference Standards
5-Aminolevulinic acid (hydrochloride) (Standard) is the analytical standard of 5-Aminolevulinic acid (hydrochloride). This product is intended for research and analytical applications. 0

HY-Y0079

D-Phenylalanine	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-Phenylalanine is an atypical D-amino acid and an inhibitor of bacterial biofilm formation. D-Phenylalanine mainly replaces D-alanine (D-Ala) by incorporating into the fourth and fifth positions of bacterial peptidoglycan (PG), changing the cell wall structure, enhancing bacterial acid resistance and affecting biofilm formation. D-Phenylalanine may promote the secretion of peptide tyrosine tyrosine (PYY) in mammals by activating the intestinal GPR109B receptor. D-Phenylalanine can inhibit the maturation of microbial biofilms and promote the release of specific hormones. It can be used for antibacterial preservation, improving the yield of probiotics in the food industry, and studying appetite regulation and blood sugar control in metabolic diseases such as diabetes .

HY-P5708

Adenoregulin Dermaseptin b2	Animals Ketones, Aldehydes, Acids Source classification	Antibiotic Fungal Bacterial
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-P1751

Ceratotoxin B	Infection Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial
Ceratotoxins B is antibacterial peptide produced by the sexually mature females of Ceratitis capitata. Lytic and antibacterial activity .

HY-P0263

Dermaseptin	Infection Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial Fungal Antibiotic
Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .

HY-P5670

Maximin 31	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 31 is an antimicrobial peptide derived from the toad brain. Maximin 31 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 37.5, 75 μg/mL, respectively .

HY-P5692

Maximin 77	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 77 is an antimicrobial peptide. Maximin 77 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 77 has hemolytic activities against human red cells .

HY-P5686

Maximin 78	Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 78 is an antimicrobial peptide. Maximin 78 has antibacterial activity against C. albicans, S. aureus, B. subtilis (MIC: 37.5, 4.7, 37.5 μg/mL). Maximin 78 has hemolytic activities against human and rabbit red cells .

HY-P5685

Maximin 49	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 49 is an antimicrobial peptide. Maximin 49 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 49 has hemolytic activities against human and rabbit red cells .

HY-P5621

Maximin 63	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 63 is an antimicrobial peptide derived from the brain of a toad. Maximin 63 has strong activity against S.aureus (MIC: 18.8 μg/mL) .

HY-P5683

Maximin 45	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 45 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus, E. coli, B. subtilis (MIC: 4.7, 9.4, 75 μg/mL). Maximin 45 has hemolytic activities against human and rabbit red cells .

HY-P0017

Aprotinin 25+ Cited Publications	Cardiovascular Disease Natural Products Animals Source classification Disease Research Fields	Influenza Virus Ser/Thr Protease
Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with K_is of 0.06 pM and 9 nM, respectively.

HY-P1539A

Cecropin A TFA	Anti-inflammation/Immunoregulatory Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Anticancer Inflammation/Immunology Disease Research Fields Cancer	Bacterial Antibiotic
Cecropin A TFA is a linear 37-residue antimicrobial polypeptide isolated from Hyalaphora cecropia pupae. Cecropin A TFA exhibits anti-bacterial, anti-inflammatory and anti-cancer activity .

HY-P0246

Mastoparan	Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

HY-N7491

Verticilide	Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Calcium Channel
Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at an IC₅₀ value of 4.2 μM (whereas inhibition against mouse ryanodine receptors was weak (IC₅₀=53.9 μM)) .

HY-P5671

Maximin 32	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 32 is an antimicrobial peptide derived from the toad brain. Maximin 32 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 9.4, 18.8 μg/mL, respectively .

Species:	Human (3) Mouse (1)
Tag:	His (3) Tag Free (1) GST (1)
Source:	HEK293 (2) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P76272

	CNDP1 Protein, Mouse (HEK293, His) Beta-ALA-His dipeptidase; CNDP dipeptidase 1; Cn1	Mouse	HEK293
	The CNDP1 protein is critical in cellular processes and catalyzes the hydrolysis of the Xaa-His dipeptide, with the highest activity against carnosine and anserine. This enzyme specificity highlights the critical role of CNDP1 in regulating the breakdown of specific dipeptides, especially those involving histidine. CNDP1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CNDP1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71641

	IFIH1 Protein, Human (His) CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140kDa; DEAD/H (Asp Glu ALA Asp/His) box polypeptide; DEAD/H box polypeptide; Helicard; Helicase with 2 CARD domains; Hlcd; MDA-5	Human	E. coli
	The IFIH1 protein is an innate immune receptor that detects viral nucleic acids and triggers an antiviral response. IFIH1 is critical for type I interferon induction and recognizes ligands such as mRNA lacking 2'-O-methylation and long double-stranded RNA. IFIH1 Protein, Human (His) is the recombinant human-derived IFIH1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P7740

	Carnosine Dipeptidase 1/CNDP1 Protein, Human (HEK293, His) rHuCarnosine Dipeptidase 1, His; Beta-ALA-His Dipeptidase; CNDP Dipeptidase 1; Carnosine Dipeptidase 1; Glutamate Carboxypeptidase-Like Protein 2; Serum Carnosinase; CNDP1; CN1; CPGL2	Human	HEK293
	Carnosine Dipeptidase 1 Protein, Human (HEK293, His) is a human carnosine dipeptidase 1 protein with a his-flag, expressed in HEK293 cells. Carnosine Dipeptidase 1 is a member of the M20 metalloprotease family, encoded by the CNDP1 gene.

HY-P703438

	hemA Protein, Rhodobacter capsulatus 5-aminolevulinate synthase; 5-aminolevulinic acid synthase; Delta-ALA synthase; Delta-aminolevulinate synthase; hemA; Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003); Acyltransferase; Transferase; 2.3.1.37	Others	E. coli
	hemA Protein, Rhodobacter capsulatus is the recombinant hemA, expressed by E. coli , with tag Free labeled tag.

HY-P71534

	DDX39B Protein, Human (GST) 0610030D10Rik; 4F2-LC6; 56kDa U2AF65-associated protein; AI428441; ATP-dependent RNA helicase p47; B(0,+)-type amino acid transporter 1; BAT1; Bat1a; D17H6S81E; D17H6S81E-1; D6S81E; D6S81Eh; DDX39B; DEAD (Asp-Glu-ALA-Asp) box polypeptide 39B; DEAD box protein UAP56; DX39B_HUMAN; EC 3.6.1.-; Glycoprotein-associated amino acid transporter b0,+AT1; HLA-B-associated transcript 1 protein; HLA-B-associated transcript 1A; HLA-B-associated transcript-1; MGC127051; MGC19235; MGC38799; nuclear RNA helicase (DEAD family); OTTHUMP00000029229; OTTHUMP00000165889; OTTHUMP00000165890; p47; Solute carrier family 7 member 9; Spliceosome RNA helicase BAT1; Spliceosome RNA helicase DDX39B; U2AF65-associayed protein; 56-KD; UAP56	Human	E. coli
	The DDX39B protein intricately coordinates nuclear mRNA export and is specifically associated with spliced mRNA as a key component of the TREX complex. This coupling of mRNA transcription, processing, and export involves rounds of ATP-dependent hydrolysis, recruiting components such as ALYREF/THOC and CHTOP. DDX39B Protein, Human (GST) is the recombinant human-derived DDX39B protein, expressed by E. coli , with N-GST labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W004066S

*Ac-Ala-OH-d3*
Ac-Ala-OH-d₃ is the deuterium labeled Ac-Ala-OH. Ac-Ala-OH is an endogenous metabolite.

HY-W009204S

*Fmoc-Ala-OH-15N*
Fmoc-Ala-OH- ¹⁵N is the ¹⁵N labeled Fmoc-Ala-OH .

HY-W009204S5

*Fmoc-Ala-OH-13C3*
Fmoc-Ala-OH- ¹³C3 is a ¹³C-labeled Fmoc-Ala-OH (HY-W009204). Fmoc-Ala-OH is an alanine derivative .

HY-W004066S1

*Ac-Ala-OH-d4*
Ac-Ala-OH-d₄ is the deuterium labeled Ac-Ala-OH. Ac-Ala-OH is an endogenous metabolite.

HY-W009204S8

*Fmoc-Ala-OH-d1*
Fmoc-Ala-OH-d is the deuterium labeled Fmoc-Ala-OH .

HY-41121S6

*Boc-L-Ala-OH-d*
Boc-L-Ala-OH-d is the deuterium labeled Boc-L-Ala-OH .

HY-W009204S6

*Fmoc-Ala-OH-d4*
Fmoc-Ala-OH-d₄ is the deuterium labeled Fmoc-Ala-OH .

HY-41121S1

*Boc-L-Ala-OH-3-13C*
Boc-L-Ala-OH-3- ¹³C is a ¹³C-labeled Boc-L-Ala-OH (HY-41121). Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein .

HY-41121S2

*Boc-L-Ala-OH-2-13C*
Boc-L-Ala-OH-2- ¹³C is a ¹³C-labeled Boc-L-Ala-OH (HY-41121). Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein .

HY-41121S4

*Boc-L-Ala-OH-15N*
Boc-L-Ala-OH- ¹⁵N is the ¹⁵N labeled Boc-L-Ala-OH.

HY-41121S5

*Boc-L-Ala-OH-d4*
Boc-L-Ala-OH-d₄ is the deuterium labeled Boc-L-Ala-OH .

HY-41121S3

*Boc-L-Ala-OH-d3*
Boc-L-Ala-OH-d₃ is the deuterium labeled Boc-L-Ala-OH .

HY-W012713S

*Ac-D-Ala-OH-d4*
Ac-D-Ala-OH-d₄ is the deuterium labeled Ac-D-Ala-OH.

HY-W008072S

*Fmoc-D-Ala-OH-d3*
Fmoc-D-Ala-OH-d₃ is the deuterium labeled Fmoc-D-Ala-OH.

HY-W009204S3

*Fmoc-Ala-OH-3-13C*
Fmoc-Ala-OH-3- ¹³C is the ¹³C labeled Fmoc-Ala-OH .

HY-W010389S2

*Ac-DL-Ala-OH-d4*
Ac-DL-Ala-OH-d₄ is the deuterium labeled Ac-DL-Ala-OH .

HY-W009204S2

*Fmoc-Ala-OH-1-13C*
Fmoc-Ala-OH-1- ¹³C is the ¹³C labeled Fmoc-Ala-OH .

HY-41121S

*Boc-Ala-OH-1-13C*
Boc-Ala-OH-1- ¹³C is the ¹³C labeled Boc-Ala-OH .

HY-W007497S

*H-β-Ala-NH2.-d4HCl*
H-β-Ala-NH2.-d₄ HCl is the deuterium labeled H-β-Ala-NH2.HCl .

HY-W009204S4

*Fmoc-Ala-OH-13C3,15N*
Fmoc-Ala-OH- ¹³C₃, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Fmoc-Ala-OH (HY-W009204). Fmoc-Ala-OH is an alanine derivative .

HY-W009204S1

*Fmoc-Ala-OH-3,3,3-d3*
Fmoc-Ala-OH-3,3,3-d₃ is the deuterium labeled Fmoc-Ala-OH-3,3,3 .

HY-173103S

*FYDPL(Ala-13C3,15N)GK TFA*
FYDPL(Ala- ¹³C₃, ¹⁵N)GK TFA is the ¹³C- and ¹⁵N-labeled FYDPL(Ala)GK TFA.

HY-P0058S

*Pramlintide-(Ala-13C3,15N)*
Pramlintide-(Ala- ¹³C₃, ¹⁵N) is the ¹³C- and ¹⁵N-labeled Pramlintide. Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer .

HY-158994S

*MEGDSRGG-(Ala-13C3,15N)-GGEA-(Leu-13C6,15N)-DPESAASSLSGAS TFA*
MEGDSRGG-(Ala- ¹³C₃, ¹⁵N)-GGEA-(Leu- ¹³C₆, ¹⁵N)-DPESAASSLSGAS TFA is a ¹³C- and ¹⁵N-labeled peptide containing ¹³C₃, ¹⁵N-labeled alanine (Ala) and ¹³C₆, ¹⁵N-labeled leucine (Leu).

HY-W751082

*H-N-Me-Ala-OH-13C,d3*
H-N-Me-Ala-OH- ¹³C,d₃ (N-Methyl-L-alanine- ¹³C,d₃) is the deuterium and ¹³C labeled H-N-Me-Ala-OH (HY-W015926). H-N-Me-Ala-OH is an alanine derivative .

HY-W052227S

*Fmoc-DL-Ala-OH-d1*
Fmoc-DL-Ala-OH-d is the deuterium labeled DL-Alanine-2-N-fmoc.

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-P6696S

*β-CL, Ala(13C3,15N) TFA*
β-CL, Ala(sup>13C₃, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled β-CL TFA.

HY-N0305S

5-Aminolevulinic acid-15N hydrochloride
5-Aminolevulinic acid- ¹⁵N (hydrochloride) is the ¹⁵N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-P1142S

*GLP-2(rat) (Ala-13C3,15N)*
GLP-2(rat) (Ala- ¹³C3, ¹⁵N) is ¹³C and ¹⁵N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).

HY-W000450S

5-Aminolevulinic acid-13C
5-Aminolevulinic acid- ¹³C is the ¹³C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-N0305S2

5-Aminolevulinic acid-13C hydrochloride
5-Aminolevulinic acid- ¹³C (hydrochloride) is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-P1142S1

*GLP-2(rat) (Ala-13C3,15N) TFA*
GLP-2(rat) (Ala- ¹³C3, ¹⁵N) TFA is ¹³C and ¹⁵N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).

HY-W749251

5-Aminolevulinic acid-13C2,15N hydrochloride
5-Aminolevulinic acid- ¹³C₂, ¹⁵N (5-ALA- ¹³C₂, ¹⁵N; δ-Aminolevulinic acid- ¹³C₂, ¹⁵N) is ¹³C- and ¹⁵N-labeled 5-Aminolevulinic acid (HY-W000450) .

HY-P1363S1

β-Amyloid (1-42), human, Ala(13C3,15N) TFA

β-Amyloid (1-42), human, Ala( ¹³C₃, ¹⁵N) TFA is the ¹³C and ¹⁵N-labeled β-Amyloid (1-42), human (HY-P1363A). β-Amyloid (1-42) (Amyloid β-peptide (1-42)), human, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 ℃, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 ℃ to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .

HY-W585933S

Fructose-alanine-13C6

Fructose-alanine- ¹³C₆ is ¹³C labeled Fructose-alanine. Fructose-alanine, an amadori compound, is an aroma precursor that formed in the initial phase of the Maillard reaction (MR). Fructose-alanine can be isolated from tobacco, miso and white wine. Fructose-alanine significantly induces oxidative browning and correlates with Maillard product (furfuryl alcohol) with a roasted and sweet aroma. Fructose-alanine can be used for food industry and tobacco processing research .

HY-W141858S

N-(3-Indolylacetyl)-L-alanine-d4
N-(3-Indolylacetyl)-L-alanine-d₄ (Indoleacetylalanine-d₄) is the deuterium labeled N-(3-Indolylacetyl)-L-alanine (HY-W141858). N-(3-Indolylacetyl)-L-alanine is an indoleacetylamino acid. N-(3-Indolylacetyl)-L-alanine appears to increase callus growth and reduces the ability of growths to differentiate into shoots of Phalaenopsis orchids .

HY-N0305S1

5-Aminolevulinic acid-d2 hydrochloride
5-Aminolevulinic acid-d₂ (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

HY-P10324

TAT-p16
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .

HY-P10285S

d-KLA Peptide-d30

d-KLA Peptide-d₃₀ (D-(KLAKLAK)2-d₃₀) is the deuterium labeled d-KLA Peptide (HY-P10285). d-KLA Peptide is a synthetic pro-apoptotic peptide. d-KLA Peptide can specifically target mitochondria and induce apoptosis by destroying the mitochondrial membrane. d-KLA Peptide activates biochemical pathways associated with apoptosis, including the activation of caspase family proteins and PARP (poly ADP ribose polymerase). d-KLA Peptide can be used to carry and deliver genes or small molecules to enhance anti-tumor effects .

HY-P0014AS

Liraglutide-d8 tetraTFA
Liraglutide-d₈ tetraTFA is deuterium labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the study of type 2 diabetes mellitus .

HY-P0014S2

Liraglutide-13C6,15N TFA
Liraglutide- ¹³C₆, ¹⁵N (TFA)is the ¹³C and ¹⁵N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .

HY-P0014S1

Liraglutide-13C5,15N TFA
Liraglutide- ¹³C₅, ¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .

HY-P1363S

β-Amyloid-15N (1-42), human TFA
β-Amyloid- ¹⁵N (1-42), human (TFA) is the ¹⁵N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .

HY-P6422S

LAVYQAGA-Arg(13C6,15N4) TFA
LAVYQAGA-Arg( ¹³C₆, ¹⁵N₄) TFA is a peptide containing ¹³C₆ and ¹⁵N₄ labeled Arg .

HY-P6423S

CLAVYQAGA-Arg(13C6,15N4) TFA
CLAVYQAGA-Arg( ¹³C₆, ¹⁵N₄) TFA is a peptide containing ¹³C₆ and ¹⁵N₄ labeled Arg .

HY-173105S

TPEEAHALSA(Pro-13C5,15N)TSR TFA
TPEEAHALSA(Pro- ¹³C₅, ¹⁵N)TSR TFA is the ¹³C- and ¹⁵N-labeled TPEEAHALSA(Pro)TSR TFA.

HY-176177S

DEKM(Leu-13C6,15N)VLWVVALSGISTLFFAA
DEKM(Leu- ¹³C₆, ¹⁵N)VLWVVALSGISTLFFAA is the ¹³C- and ¹⁵N-labeled DEKMVLWVVALSGISTLFFAA.

HY-159192S

SADDNIKTPAE(Arg-13C6,15N4)LLGPLPPSADDNLKT TFA
SADDNIKTPAE(Arg- ¹³C6, ¹⁵N4)LLGPLPPSADDNLKT (TFA) is the ¹³C and ¹⁵N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .

HY-P4229

([D8]Val7,10)-C-Peptide (human)
([D8]Val7,10)-C-Peptide (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83276

	ALAS1 Antibody (YA3021) ALAS1; ALAS-H; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; ALAS3; ALASH	WB, ICC/IF	Human
	ALAS1 Antibody (YA3021) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ALAS1.

HY-P81106

	IL-8/CXCL8 Antibody 1 Publications Verification Interleukin 8; Interleukin8; (ALA-IL-8)77; (Ser-IL-8)72; 3 10C; 310C; AMCF1; b ENAP; CXC chemokine ligand 8; CXCL 8; CXCL8; Emoctakin; GCP-1; GCP1; IL 8; IL-8; IL-8(1-77); IL-8(9-77); IL8; LYNAP; MDNCF; MDNCF-b; MDNCF-c; MONAP; NAF; NAP-1; NAP1; Protein 3 10C; Protein 3-10C; SCYB 8; SCYB8; TSG1.	ELISA, IHC-P, IHC-F, ICC/IF	Human, Rabbit
	IL-8/CXCL8 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to IL-8/CXCL8.

HY-P87154

	ddx24 Antibody (YA6847) DEAD (Asp-Glu-ALA-Asp) box helicase 24 antibody; ddx24 antibody;	IHC-P, IF-Tissue	Zebrafish
	ddx24 Antibody (YA6847) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ddx24.

HY-P85604

	DDX3 Antibody (YA5296) ATP dependent RNA helicase DDX3X; ATP-dependent RNA helicase DDX3X; CAP Rf; DBX; DDX14; DDX3X; DDX3X_HUMAN; DEAD; Asp Glu ALA Asp; box polypeptide 3 X linked; DEAD box; DEAD box protein 3; DEAD box protein 3 X-chromosomal; DEAD box X isoform; DEAD/H; Asp Glu ALA Asp/His; box polypeptide 3; DEAD/H box 3; DEAD/H box 3, X-linked; Fibroblast Growth Factor Inducible 14; Fin14; Helicase like protein 2; Helicase-like protein 2; HLP2; X isoform; X-chromosomal.	WB, IP, ICC	Human, Rat, Mouse, Monkey
	DDX3 Antibody (YA5296) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to DDX3.

HY-P85498

	IL-8/CXCL8 Antibody (YA5190) ALA-IL-8; 77; Ser-IL-8; 72; 3 10C; 310C; AMCF 1; AMCF1; b ENAP; Bbeta thromboglobulin like protein; Beta thromboglobulin like protein; C-X-C motif chemokine 8; CXC chemokine ligand 8; CXCL 8; CXCL8; Emoctakin; GCP 1; GCP-1; GCP/IL-8 protein I; GCP/IL-8 protein II; GCP/IL-8 protein III; GCP/IL-8 protein IV; GCP/IL-8 protein V; GCP/IL-8 protein VI; GCP1; Granulocyte chemotactic protein 1; IL 8; IL-8; IL-8; 1-77; IL-8; 9-77; IL8; IL8/NAP1 form I; IL8/NAP1 form II; IL8/NAP1 form III; IL8/NAP1 form IV; IL8/NAP1 form V; IL8/NAP1 form VI; IL8_HUMAN; Inteleukin 8; Interleukin8; K 60; K60; LECT; LUCT; Lymphocyte derived neutrophil activating factor; Lymphocyte-derived neutrophil-activating factor; LYNAP; MDNCF; MDNCF-b; MDNCF-c; MONAP; Monocyte derived neutrophil activating peptide; Monocyte derived neutrophil activating protein; Monocyte derived neutrophil chemotactic factor; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; NAF; NAP 1; NAP-1; NAP1; Neutrophil activating factor; Neutrophil activating peptide 1; Neutrophil activating protein 1; Neutrophil-activating factor; Neutrophil-activating protein 1; Protein 3 10C; Protein 3-10C; SCYB 8; SCYB8; Small inducible cytokine subfamily B member 8; T cell chemotactic factor; T-cell chemotactic factor; TSG 1; TSG1;	WB, ELISA	Human
	IL-8/CXCL8 Antibody (YA5190) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to IL-8/CXCL8.

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Cat. No.	Product Name		Classification

HY-162946

Alkyne-P60		Alkynes
Alkyne-P60 is a potent 15-mer peptide inhibitor of Foxp3. Alkyne-P60 can bind with Foxp3, hinder its nuclear translocation, and diminish Foxp3-mediated inhibition of NFKB and NFAT functions. Alkyne-P60 is a ligand for target protein for PROTAC (HY-162943).

HY-141152

*Azido-PEG4-Ala-Ala-Asn(Trt)-PAB*		Azide
Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a cleavable ADC linker.

HY-141150

*Azido-PEG5-Ala-Ala-Asn-PAB*		Azide ADC Synthesis
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140850

Azide-PEG3-C1-Ala		PROTAC Synthesis Azide
Azide-PEG3-C1-Ala is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG3-C1-Ala is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W591373

*DBCO-PEG4-Val-Ala-PAB*		DBCO
DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.

HY-151664

*H-alpha-Prg-D-Ala-OH*		Alkynes
H-alpha-Prg-D-Ala-OH is a click chemistry reagent containing an azide group .

HY-W591374

*DBCO-PEG4-Val-Ala-PAB-PNP*		DBCO
DBCO-PEG4-Val-Ala-PAB-PNP is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility. PNP is a good leaving group.

HY-151740

*4-Pentynoyl-Val-Ala-PAB-PNP*		ADC Synthesis Alkynes
4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates . 4-Pentynoyl-Val-Ala-PAB-PNP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140849

*Azido-PEG3-Ala-Boc*		Azide PROTAC Synthesis
Azido-PEG3-Ala-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-Ala-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151739

*4-Pentynoyl-Val-Ala-PAB*		Alkynes
4-Pentynoyl-Val-Ala-PAB is a click chemical class ADC linker. Click chemistry has good biological orthogonality characteristics: biocompatible, fast and highly specific in the biological environment, and has great application potential in the binding between nucleic acids, lipids, proteins and other molecules .

HY-P10928

BCY17901 TFA		Azide
BCY17901 TFA is a potent irreversible transferrin receptor 1 (TfR1) inhibitor (K_i=12 nM). BCY17901 TFA inhibits TfR1-mediated endocytosis and iron transport, and suppresses the proliferation of tumor cells dependent on iron metabolism. BCY17901 TFA can be used in the research of solid tumors (such as breast cancer, glioblastoma) and neurodegenerative diseases .

Cat. No.	Product Name		Classification

HY-111627

5-Aza-7-deazaguanine 1 Publications Verification		Nucleoside Analogs Guanosine
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides .

HY-132610A

Givosiran sodium 1 Publications Verification ALN-AS1 sodium		siRNAs siRNA drugs
Givosiran (ALN-AS1) sodium is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran sodium downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran sodium demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran sodium can be used for the research of acute hepatic porphyria (AHP) .

HY-132610

Givosiran 1 Publications Verification ALN-AS1		siRNAs siRNA drugs
Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran can be used for the research of acute hepatic porphyria (AHP) .

HY-166997

AL-A12		Cationic Lipids
AL-A12 is a short-chain amino lipid with high gene delivery efficiency and low toxicity, and can be used in drug delivery research .

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