2. GPCR/G Protein
  3. Natriuretic Peptide Receptor (NPR)
  4. ANP [Des18-22] 4-23 amide (rat)

ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C.

For research use only. We do not sell to patients.

ANP [Des18-22] 4-23 amide (rat)

ANP [Des18-22] 4-23 amide (rat) Chemical Structure

CAS No. : 111863-73-1

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Based on 1 publication(s) in Google Scholar

ANP [Des18-22] 4-23 amide (rat) Related Antibodies

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Description

ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C[1][2].

Molecular Weight

1594.82

Formula

C64H107N25O19S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Cys-NH2 (disulfide bridge:Cys4-Cys15)
Sequence Shortening

RSSCFGGRIDRIGAC-NH2 (disulfide bridge:Cys4-Cys15)
SMILES

O=C([C@H](CSSC[C@H](NC([C@@H](NC(CNC([C@](NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC(CNC(CNC1=O)=O)=O)CCCNC(N)=N)=O)([H])[C@@H](C)CC)=O)CC(O)=O)=O)CCCNC(N)=N)=O)([H])[C@@H](C)CC)=O)=O)C)=O)C(N)=O)NC([C@H](CO)NC([C@H](CO)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)N[C@H]1CC2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (15.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6270 mL 3.1352 mL 6.2703 mL
5 mM 0.1254 mL 0.6270 mL 1.2541 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6270 mL 3.1352 mL 6.2703 mL 15.6758 mL
5 mM 0.1254 mL 0.6270 mL 1.2541 mL 3.1352 mL
10 mM 0.0627 mL 0.3135 mL 0.6270 mL 1.5676 mL
15 mM 0.0418 mL 0.2090 mL 0.4180 mL 1.0451 mL
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ANP [Des18-22] 4-23 amide (rat) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ANP [Des18-22] 4-23 amide (rat)111863-73-1Natriuretic Peptide Receptor (NPR)Natriuretic Peptide ReceptorNPRNPR-ANPR-BNPR-CCHOrat mesangial cellsInhibitorinhibitorinhibit

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