1. Peptides
  2. Peptide and Derivatives
  3. Peptides for Drug Delivery
  4. Cell-penetrating Peptides
  5. gH625

gH625 is a cell-penetrating viral peptide which is a part of glycoprotein H of Herpes simplex virus type I. gH625 is able to cross the cell membrane and to transport many conjugated cargoes into the cytosol. gH625 is permeable to the blood-brain barrier (BBB) and can enter the rat brain in vivo without toxic effects. gH625 can be used for siRNA delivery research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

gH625 Chemical Structure

gH625 Chemical Structure

CAS No. : 1360823-60-4

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Description

gH625 is a cell-penetrating viral peptide which is a part of glycoprotein H of Herpes simplex virus type I. gH625 is able to cross the cell membrane and to transport many conjugated cargoes into the cytosol. gH625 is permeable to the blood-brain barrier (BBB) and can enter the rat brain in vivo without toxic effects. gH625 can be used for siRNA delivery research[1].

Molecular Weight

2297.62

Formula

C106H161N33O25

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

His-Gly-Leu-Ala-Ser-Thr-Leu-Thr-Arg-Trp-Ala-His-Tyr-Asn-Ala-Leu-Ile-Arg-Ala-Phe-NH2

Sequence Shortening

HGLASTLTRWAHYNALIRAF-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (43.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4352 mL 2.1762 mL 4.3523 mL
5 mM 0.0870 mL 0.4352 mL 0.8705 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4352 mL 2.1762 mL 4.3523 mL 10.8808 mL
5 mM 0.0870 mL 0.4352 mL 0.8705 mL 2.1762 mL
10 mM 0.0435 mL 0.2176 mL 0.4352 mL 1.0881 mL
15 mM 0.0290 mL 0.1451 mL 0.2902 mL 0.7254 mL
20 mM 0.0218 mL 0.1088 mL 0.2176 mL 0.5440 mL
25 mM 0.0174 mL 0.0870 mL 0.1741 mL 0.4352 mL
30 mM 0.0145 mL 0.0725 mL 0.1451 mL 0.3627 mL
40 mM 0.0109 mL 0.0544 mL 0.1088 mL 0.2720 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
gH625
Cat. No.:
HY-P10153
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