ddx24 Antibody (YA6847)

Cat. No.: HY-P87154: Data Sheet User Guide for Antibodies
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ddx24 Antibody (YA6847) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ddx24.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ddx24 Antibody (YA6847) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ddx24.

Host

Mouse

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 94.5 kDa

Species Reactivity

Zebrafish

SwissProt ID

Q9GZR7

Gene ID

57062 [NCBI]

Immunogen

Recombinant protein within zebrafish ddx24 aa 562-819 / 832.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:50

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：ATP-dependent RNA helicase that plays a role in various aspects of RNA metabolism including pre-mRNA splicing and is thereby involved in different biological processes such as cell cycle regulation or innate immunity (PubMed:24204270, PubMed:24980433). Plays an inhibitory role in TP53 transcriptional activity and subsequently in TP53 controlled cell growth arrest and senescence by inhibiting its EP300 mediated acetylation (PubMed:25867071). Negatively regulates cytosolic RNA-mediated innate immu

Subcellular Localization：Cytoplasm; Nucleus

Subunit：Interacts with FADD (PubMed:24204270). Interacts with RIPK1; this interaction disrupts RLR signaling activation of IFN-dependent transcription factor IRF7 (PubMed:24204270). Interacts with NIP7 (PubMed:24980433). Interacts with EP300; this interaction prevents TP53 acetylation mediated by EP300 (PubMed:25867071)

Synonyms

DEAD (Asp-Glu-Ala-Asp) box helicase 24 antibody; ddx24 antibody;

Documentation

User Guide for Antibodies (1077 KB)