2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. Drug-Linker Conjugates for ADC Topoisomerase
  4. Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan

Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan (compound 12) is a Drug-Linker Conjugate for ADC. Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan contains the ADC linker (Mc-Lys(PEG12)-Cap-Ala-Ala-PABC) (HY-178146) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan can be used for the development of ADC targeting HER2-positive breast cancer.

For research use only. We do not sell to patients.

Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan

Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan Chemical Structure

CAS No. : 3067680-81-0

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Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan Related Antibodies

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Description

Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan (compound 12) is a Drug-Linker Conjugate for ADC. Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan contains the ADC linker (Mc-Lys(PEG12)-Cap-Ala-Ala-PABC) (HY-178146) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan can be used for the development of ADC targeting HER2-positive breast cancer[1].

Molecular Weight

1731.95

Formula

C86H123FN10O26
CAS No.
SMILES

CC[C@]1(C(OCC2=C1C=C3C4=NC5=CC(F)=C(C6=C5C([C@H](CC6)NC(OCC7=CC=C(C=C7)NC([C@@H](NC([C@@H](NC(CCCCCNC([C@@H](NC(CCCCCN8C(C=CC8=O)=O)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)C)=O)C)=O)=O)=C4CN3C2=O)C)=O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan Related Classifications

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Keywords:

Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan3067680-81-0Drug-Linker Conjugates for ADCTopoisomerasebreast cancerInhibitorinhibitorinhibit

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Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan
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