2. GPCR/G Protein Immunology/Inflammation Stem Cell/Wnt MAPK/ERK Pathway
  3. CXCR ERK
  4. Peptide R analogue 10

Peptide R analogue 10 (compound 10) is an analog of the CXCR4 antagonist peptide Peptide R (HY-P4111) with stronger antagonistic potency, specificity and plasma stability. Peptide R analogue 10 can inhibit CXCL12-mediated cell migration, ERK phosphorylation and CXCR4 internalization. Peptide R analogue 10 can be used in the study of CXCR4 overexpressing leukemia and colon cancer.

For research use only. We do not sell to patients.

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Peptide R analogue 10 Chemical Structure

Peptide R analogue 10 Chemical Structure

CAS No. : 1998129-59-1

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Peptide R analogue 10 Related Antibodies

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Description

Peptide R analogue 10 (compound 10) is an analog of the CXCR4 antagonist peptide Peptide R (HY-P4111) with stronger antagonistic potency, specificity and plasma stability. Peptide R analogue 10 can inhibit CXCL12-mediated cell migration, ERK phosphorylation and CXCR4 internalization. Peptide R analogue 10 can be used in the study of CXCR4 overexpressing leukemia and colon cancer[1].

IC50 & Target

CXCR4

 

Molecular Weight

1884.24

Formula

C82H118N26O18S4
CAS No.
Sequence

Ac-Arg-Ala-cyclo{{d-Cys}-Arg-Phe-Phe-Cys}-COOH
Sequence Shortening

Ac-RA-cyclo{{d-Cys}RFFC}-COOH
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Peptide R analogue 10 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Peptide R analogue 101998129-59-1Peptide R analogue10Peptide R analogue-10CXCRERKCXC chemokine receptorsC-X-C motif chemokine receptorsExtracellular signal regulated kinasesInhibitorinhibitorinhibit

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HY-P10973
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