2. GPCR/G Protein
  3. Secretin Receptor
  4. Secretin (33-59), rat TFA

Secretin (33-59), rat TFA  (Synonyms: Secretin (rat) (TFA))

Cat. No.: HY-P1244A Purity: 98.11%
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Handling Instructions Technical Support

Secretin (33-59), rat (TFA) is a 27-aa peptide, which acts on secretin receptor, and enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Secretin (33-59), rat TFA

Secretin (33-59), rat TFA Chemical Structure

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Secretin (33-59), rat TFA:

Secretin (33-59), rat TFA Related Antibodies

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Description

Secretin (33-59), rat (TFA) is a 27-aa peptide, which acts on secretin receptor, and enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas[1][2].

IC50 & Target

Secretin receptor[2]
Molecular Weight

3141.37

Formula

C131H217F3N42O44
Appearance

Solid

Color

White to off-white

Sequence

His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Gln-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2
Sequence Shortening

HSDGTFTSELSRLQDSARLQRLLQGLV-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (31.83 mM; Need ultrasonic)

DMSO : 100 mg/mL (31.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3183 mL 1.5917 mL 3.1833 mL
5 mM 0.0637 mL 0.3183 mL 0.6367 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.3183 mL 1.5917 mL 3.1833 mL 7.9583 mL
5 mM 0.0637 mL 0.3183 mL 0.6367 mL 1.5917 mL
10 mM 0.0318 mL 0.1592 mL 0.3183 mL 0.7958 mL
15 mM 0.0212 mL 0.1061 mL 0.2122 mL 0.5306 mL
20 mM 0.0159 mL 0.0796 mL 0.1592 mL 0.3979 mL
25 mM 0.0127 mL 0.0637 mL 0.1273 mL 0.3183 mL
30 mM 0.0106 mL 0.0531 mL 0.1061 mL 0.2653 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Secretin (33-59), rat TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Secretin (33-59), ratSecretin (rat) (TFA)Secretin ReceptorSCTRInhibitorinhibitorinhibit

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