1. Cytoskeleton
  2. Integrin
  3. Integrin signaling inhibitor, mP13

Integrin signaling inhibitor, mP13 is an inhibitor of integrin signaling. Integrin signaling inhibitor, mP13 inhibits inside-out and outside-in signaling, including fibrinogen binding, platelet adhesion, and clot retraction.

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Integrin signaling inhibitor, mP13 Chemical Structure

Integrin signaling inhibitor, mP13 Chemical Structure

CAS No. : 1335046-19-9

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Based on 1 publication(s) in Google Scholar

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Description

Integrin signaling inhibitor, mP13 is an inhibitor of integrin signaling. Integrin signaling inhibitor, mP13 inhibits inside-out and outside-in signaling, including fibrinogen binding, platelet adhesion, and clot retraction[1].

Molecular Weight

1876.16

Formula

C87H138N22O24

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Myr}-Lys-Phe-Glu-Glu-Glu-Arg-Ala-Arg-Ala-Lys-Trp-Asp-Thr

Sequence Shortening

{Myr}-KFEEERARAKWDT

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (53.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5330 mL 2.6650 mL 5.3300 mL
5 mM 0.1066 mL 0.5330 mL 1.0660 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5330 mL 2.6650 mL 5.3300 mL 13.3251 mL
5 mM 0.1066 mL 0.5330 mL 1.0660 mL 2.6650 mL
10 mM 0.0533 mL 0.2665 mL 0.5330 mL 1.3325 mL
15 mM 0.0355 mL 0.1777 mL 0.3553 mL 0.8883 mL
20 mM 0.0267 mL 0.1333 mL 0.2665 mL 0.6663 mL
25 mM 0.0213 mL 0.1066 mL 0.2132 mL 0.5330 mL
30 mM 0.0178 mL 0.0888 mL 0.1777 mL 0.4442 mL
40 mM 0.0133 mL 0.0666 mL 0.1333 mL 0.3331 mL
50 mM 0.0107 mL 0.0533 mL 0.1066 mL 0.2665 mL
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Integrin signaling inhibitor, mP13 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Integrin signaling inhibitor, mP13
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