1. Vitamin D Related/Nuclear Receptor
  2. Thyroid Hormone Receptor
  3. DPC-AJ1951 TFA

DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption.

For research use only. We do not sell to patients.

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DPC-AJ1951 TFA Chemical Structure

DPC-AJ1951 TFA Chemical Structure

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Description

DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption[1].

In Vitro

DPC-AJ1951 TFA induces intracellular Ca2+ mobilization in HEK 293 cells transfected with the human PPR (EC50 26±14 nM)[1][1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1666.99 (free base)

Formula

C76H127N23O19.xC2HF3O2

Appearance

Solid

Color

White to off-white

Sequence

{Aib}-Val-{Aib}-Glu-Ile-Gln-Leu-{Nle}-His-Gln-Arg-Ala-Lys-Tyr-NH2

Sequence Shortening

{Aib}V{Aib}EIQL{Nle}HQRAKY-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DPC-AJ1951 TFA
Cat. No.:
HY-P1418A
Quantity:
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