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LAH4-L1 Is a histidine-rich cell penetrating peptide. LAH4-L1 can form complexes with DNA or siRNA and help their transport.

For research use only. We do not sell to patients.

LAH4-L1 Chemical Structure

LAH4-L1 Chemical Structure

CAS No. : 882690-68-8

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Based on 1 publication(s) in Google Scholar

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Description

LAH4-L1 Is a histidine-rich cell penetrating peptide. LAH4-L1 can form complexes with DNA or siRNA and help their transport[1].

Molecular Weight

2779.46

Formula

C132H228N38O27

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Lys-Ala-Leu-Leu-Ala-His-Ala-Leu-His-Leu-Leu-Ala-Leu-Leu-Ala-Leu-His-Leu-Ala-His-Ala-Leu-Lys-Lys-Ala

Sequence Shortening

KKALLAHALHLLALLALHLAHALKKA

SMILES

OC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC1=CN=CN1)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC2=CN=CN2)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(C)C)NC([C@H](C)NC([C@@H](NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (7.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.3598 mL 1.7989 mL 3.5978 mL
5 mM 0.0720 mL 0.3598 mL 0.7196 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.3598 mL 1.7989 mL 3.5978 mL 8.9946 mL
5 mM 0.0720 mL 0.3598 mL 0.7196 mL 1.7989 mL
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LAH4-L1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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LAH4-L1
Cat. No.:
HY-P10733
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