1. Peptides
  2. Peptide and Derivatives
  3. Peptide Epitopes
  4. GADGVGKSA

GADGVGKSA is a mutant KRAS G12D 9mer peptide. GADGVGKSA can be used as an immunogenic neoantigen for cancer immunotherapy research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GADGVGKSA Chemical Structure

GADGVGKSA Chemical Structure

CAS No. : 2032119-68-7

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Based on 1 publication(s) in Google Scholar

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Description

GADGVGKSA is a mutant KRAS G12D 9mer peptide. GADGVGKSA can be used as an immunogenic neoantigen for cancer immunotherapy research[1].

Molecular Weight

760.79

Formula

C30H52N10O13

CAS No.
Appearance

Solid

Color

Colorless to off-white

Sequence

Gly-Ala-Asp-Gly-Val-Gly-Lys-Ser-Ala

Sequence Shortening

GADGVGKSA

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (131.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3144 mL 6.5721 mL 13.1442 mL
5 mM 0.2629 mL 1.3144 mL 2.6288 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3144 mL 6.5721 mL 13.1442 mL 32.8606 mL
5 mM 0.2629 mL 1.3144 mL 2.6288 mL 6.5721 mL
10 mM 0.1314 mL 0.6572 mL 1.3144 mL 3.2861 mL
15 mM 0.0876 mL 0.4381 mL 0.8763 mL 2.1907 mL
20 mM 0.0657 mL 0.3286 mL 0.6572 mL 1.6430 mL
25 mM 0.0526 mL 0.2629 mL 0.5258 mL 1.3144 mL
30 mM 0.0438 mL 0.2191 mL 0.4381 mL 1.0954 mL
40 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.8215 mL
50 mM 0.0263 mL 0.1314 mL 0.2629 mL 0.6572 mL
60 mM 0.0219 mL 0.1095 mL 0.2191 mL 0.5477 mL
80 mM 0.0164 mL 0.0822 mL 0.1643 mL 0.4108 mL
100 mM 0.0131 mL 0.0657 mL 0.1314 mL 0.3286 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GADGVGKSA
Cat. No.:
HY-P3488
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