1. GPCR/G Protein
  2. GLP Receptor
  3. Liraglutide TFA

Liraglutide (TFA) is an agonist of glucagon-like peptide 1 receptor (GLP-1). Liraglutide (TFA) can activate GLP-1, leading to the release of insulin in the presence of increased glucose concentration. Liraglutide (TFA) also reduces glucagon secretion in a glucose-dependent manner. Liraglutide (TFA) can be studied in research on type 2 diabetes.

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Liraglutide TFA

Liraglutide TFA Chemical Structure

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Top Publications Citing Use of Products

    Liraglutide TFA purchased from MedChemExpress. Usage Cited in: Am J Physiol Renal Physiol. 2020 Sep 1;319(3):F458-F468.  [Abstract]

    Representative Western blot showing FN protein abundance in HMCs cultured in media containing 5.5 mM glucose (NG) or 5.5 mM glucose + 19.5 mM mannitol (NG+M) or 25 mM glucose (HG) in the absence or presence of liraglutide at different concentrations (1 nM, 10 nM, 100 nM, 1000 nM) for 24h.

    Liraglutide TFA purchased from MedChemExpress. Usage Cited in: Mol Med Rep. 2016 Oct;14(4):3662-8.  [Abstract]

    Effects of Liraglutide treatment on Alp and OC protein expression levels, and matrix mineralization. Following culture in commercial osteogenic differentiation medium for 14 days, MC3T3-E1 cells are cultured for an additional 14 days in basal culture medium with various concentrations of Liraglutide (0, 0.1, 0.5, 1, 2 and 4 nM). MC3T3-E1 cells maintained in DMEM for 28 days with no treatment are used as the NC; cells cultured in the commercial osteogenic differentiation medium for 14 days and in
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    Description

    Liraglutide (TFA) is an agonist of glucagon-like peptide 1 receptor (GLP-1). Liraglutide (TFA) can activate GLP-1, leading to the release of insulin in the presence of increased glucose concentration. Liraglutide (TFA) also reduces glucagon secretion in a glucose-dependent manner. Liraglutide (TFA) can be studied in research on type 2 diabetes[1].

    Molecular Weight

    3751.20 (free base)

    Formula

    C172H265N43O51.xC2HF3O2

    Sequence

    His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-{Lys(γGlu-C16 acid)}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly

    Sequence Shortening

    HAEGTFTSDVSSYLEGQAA-{Lys(γGlu-C16 acid)}-EFIAWLVRGRG

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Liraglutide TFA
    Cat. No.:
    HY-P0014B
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